Principles and Target Product Criteria. Roadmap January 12, 2015
Clinical management standard operating procedures.
Ebola virus disease (EVD) is a life-threatening multisystem illness associated with fever and gastrointestinal (GI) symptoms that frequently leads to hypovolaemia, metabolic acidosis, hypoglycaemia
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, and multi-organ failure. The prolonged 2013–2016 EVD outbreak in West Africa allowed for an evolution of care such that by outbreak end many patients received individualized and optimized supportive care (oSoC), including volume resuscitation, symptom control, laboratory and bedside monitoring of glucose, electrolyte levels and organ dysfunction, as well as rapid detection and treatment of co-infections, potentially contributing to the downward trend in the case fatality rate (CFR).
This guidance should serve as a foundation for oSoC that should be followed to ensure both the best possible chance for survival and allow for reliable comparison of investigational therapeutic interventions as part of a randomized controlled trial. This guideline provides recommendations for the management of adults and children.
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The funding requested in this supplementary appeal will enable UNHCR to enhance preventive, preparedness and response measures against EVD, participate in the regional and country inter-agency response and ensure continuity of operations, including preparations for the resumption of the voluntary re
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patriation of Ivorian refugees, in the face of the Ebola crisis
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This clinical management manual for Ebola Viral Disease in Liberia was developed after several ETUs were established in the country following the outbreak early this year. As the outbreak evolved, it became evident that different SOPs were being use
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d by clinicians across these treatment facilities. As a result of discussions held by the National Case Management Committee of the Incident Management System, various stakeholders were brought together to contribute their time and expertise to the development of this manual.
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The Emergency Ministerial meeting on Ebola Virus Disease (EVD) with Health Ministers agreeing on a range of priority actions to end the Ebola outbreak in West
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Africa. The scale of the ongoing outbreak is unprecedented with reports of over 750 cases and 445 deaths in Guinea, Sierra Leone and Liberia since March 2014.
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The main objective of this mission was to assess the level of preparedness of Guinea-Bissau in respect of the WHO consolidated checklist. The checklist helps countries to assess and test their level of readiness it is being used to identify concrete action to be taken and where countries will requir
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e support from partners. It lists 10 key components and tasks for both countries and the international community that should be completed within 30, 60 and 90 days from the date of issue of the list, with minimal requirements for equipment, material and human resources.
The components include: overall coordination; rapid response teams; public awareness and community engagement; infection prevention and control; epidemiological and laboratory surveillance; contact tracing; points of entry; laboratory; social mobilization and risk communication; budget.
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CAFOD Policy Briefing Paper
This document provides information to assist countries in developing exit screening plans and Standard Operating Procedures (SOP). This includes the method, tools, and sequence of screening; determining resource needs; communication messages; and the legal considerations of screening
This interim guidance to national health authorities and blood transfusion services outlines the steps required to collect convalescent whole blood (CWB) or plasma (CP) from Ebola virus disease (EVD) recovered patients for transfusion to patients w
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ith early EVD, as an empirical treatment modality.
Document contents:
Guidance on donor selection, screening, donation and handling of blood and plasma units;
guidance on transfusion of convalescent whole blood or plasma;
other considerations.
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Ebola Virus Disease Outbreak Response Plan in West Africa July to December 2014. Annex 1
Sierra Leone Trial to Introduce a Vaccine against Ebola (STRIVE)