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Cystic Fibrosis - What Is Cystic Fibrosis

National Heart, Lung, and Blood Institute (NHLBI) U.S. Department of Health and Human Services (2024) CC2

The "Cystic Fibrosis Fact Sheet" by the National Heart, Lung, and Blood Institute provides an overview of cystic fibrosis (CF), a chronic and often fatal genetic disorder affecting the respiratory and digestive systems. The document outlines the causes, genetic inheritance patterns, and symptoms of ... more

The Burden of Pediatric Asthma

Ferrante, G.; La Grutta, S. Frontiers in Pediatrics (2018) CC

Asthma is the most common chronic disease in children, imposing a consistent burden on health system. In recent years, prevalence of asthma symptoms became globally increased in children and adolescents, particularly in Low-Middle Income Countries (LMICs). Host (genetics, atopy) and environmental fa... more

Risk factors for asthma among schoolchildren who participated in a casecontrol study in urban Uganda

Mpairwe, H.; Namutebi, M.; Nkurunungi, G. et al. eLife (2019) CC

Data on asthma aetiology in Africa are scarce. We investigated the risk factors for asthma among schoolchildren (5–17 years) in urban Uganda. We conducted a case-control study, among 555 cases and 1115 controls. Asthma was diagnosed by study clinicians. The main risk factors for asthma were tertia... more

Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

Worldwide rates of diagnosis and effective treatment for cystic fibrosis

Guo, J.; Garratt, A.; Hill, A. Journal of Cystic Fibrosis (2022) CC

Time has seen management for Cystic Fibrosis (CF) advance drastically, most recently in the development of the disease-modifying triple combination therapy ivacaftor/tezacaftor/elexacaftor. There is currently limited evidence regarding both the global epidemiology of CF and access to this transforma... more

Polio Vaccine Security Framework

Global Polio Eradication Initiative GPEI (2025) CC

Long-term polio vaccine security – the timely, sustained, and uninterrupted supply of suitable types of affordable, quality-assured polio vaccines – is essential in the global effort to achieve and maintain a polio free world. However, fragmented approaches and short-term planning pose considera... more

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Safety and quality of water used with fresh fruits and vegetables

Food and Agriculture Organization of the United Nations FAO; World Health Organization (WHO) (2021) C_WHO

During fresh fruit and vegetables (FFV) production, water is used for a variety of purposes. Even the water was conventionally treated and disinfected, it may still potentially contain human pathogens, albeit at low concentrations. A risk assessment, appropriate to the national or local production c... more

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Recommandations de l’OMS concernant les soins prénatals pour que la grossesse soit une expérience positive. Résumé d’orientation

Organisation mondiale de la Santé (OMS) (2016) C_WHO

En 2016, en ce début de l’ère des objectifs de développement durable (ODD), la morbidité et la mortalité évitables liées à la grossesse restent inacceptablement élevées. Bien que des progrès substantiels aient été enregistrés, les pays doivent consolider et faire progresser ces acqui... more

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Module: Other significant mental health complaints

WHO WHO (2015) C_WHO

Overview Learning objectives • Promote respect and dignity for people with other significant mental health complaints. • Know the common presentation of other significant mental health complaints. • Know the assessment principles of other significant mental health complaints. • Know the... more

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Review on palliative care with focus on 18 high tuberculosis priority countries

World Health Organization WHO, Regional Office of Europe (2021) C_WHO

Tuberculosis (‎TB)‎ is, and should be, a curable disease; however, each year significant numbers of patients acquire or develop drug-resistant TB, which has a much lower cure rate. Patients with drug-resistant TB have a high prevalence of symptoms; hence, staff caring for these patients should h... more

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Manual de Biossegurança Laboratorial. Quarta Edição

Organización Mundial de la Salud OMS PAHO (2021) C_WHO

Esta quarta edição do manual se baseia no esquema de avaliação de risco apresentado na terceira edição. Uma avaliação completa, baseada em evidências e transparente dos riscos permite que as medidas de segurança sejam equilibradas com o risco real de trabalhar com agentes biológicos, caso... more

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Training manual for surveillance of suicide and self-harm in communities via key informants

World Health Organisation (WHO) (2023) C_WHO

More than 700 000 people lose their life to suicide every year. A core foundation of suicide prevention is the timely registration and regular monitoring of suicide and self-harm. Surveillance data can be used to show important progress towards reaching global targets, such as reducing the suicide r... more

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AidData's Methodology for Tracking Underreported Financial Flows, Version 1.1.

Strange, A. M.; B. O’Donnell; D. Gamboa et al. AidData at William & Mary (2013) CC

AidData has developed a set of open source data collection methods to track project-level data on suppliers of official finance who do not participate in global reporting systems. This codebook outlines the version 1.1 set of TUFF procedures that have been developed, tested, refined, and implemented... more

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Informe sobre la situación mundial de la salud bucodental: hacia la cobertura sanitaria universal para la salud bucodental de aquí a 2030: resumen ejecutivo

World Health Organisation (WHO) (2022) C_WHO

El resumen ejecutivo del Informe de la OMS sobre la situación mundial de la salud bucodental presenta una instantánea de los datos más recientes sobre las principales enfermedades bucodentales, los factores de riesgo, los retos para los sistemas de salud y las oportunidades de reforma. La clara c... more

Rapport d'évaluation des capacités nationales pour la réduction des risques, la préparation et la réponse aux urgences au Burkina Faso

Ministère de la Santé, Burkina Faso (2015) C2

Le Burkina Faso est un pays sahélien sans littoral d’une superficie de 274 000 km2 et une population estimée à 17,4 millions d’habitants en 2013 avec une croissance démographique de 3,1%. C’est l’un des pays les plus pauvres du monde avec un Produit intérieur brut par tête de 684 US... more

Cultures constructives locales pour la résilience et le développement

The International Federation of Red Cross and Red Crescent Societies IFRC; CRA Terre; et al. (2017) CC

Partout dans le monde, les sociétés ont produit, adapté et fait évoluer leur habitat pour répondre au mieux à leurs besoins et aspirations, et ce en faisant le meilleur usage des ressources naturelles disponibles localement et en développant leurs propres capacités. Les stratégies qui e... more

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Expanding the Roles of Nurses in Primary Health Care

Pan American Health Organization (PAHO), World Health Organization - Regional Office for the Americas (WHO) (2018) C_WHO

[Preface]. For more than forty years Primary Health Care (PHC) has been recognized as the cornerstone of an effective and responsive health system. The Alma-Ata Declaration of 1978 reaffirmed the right to the highest attainable level of health, with equity, solidarity and the right to health as its ... more

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How to use the ICF: A practical manual for using the International Classification of Functioning, Disability and Health (ICF). Exposure draft for comment.

World Health Organization (WHO) (2013) C_WHO

The ICF Practical Manual provides information on how to use ICF. Anyone interested in learning more about use of the International Classification of Functioning, Disability and Health (ICF, WHO 2001) may benefit from reading this Practical Manual. The ICF is presently used in many different contexts... more

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2015 Size Estimation of Key Affected Populations in the Philippines

Philippines, Department of Health, Epidemiology Bureau (2016) C1

Estimating the size of key affected populations (KAP) provides important data for planning and implementing an effective response to the HIV epidemic. In the Philippines, these KAP include males who have sex with males (MSM), female sex workers (FSW), and injecting drug users (IDU). Given the diffic... more

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Pharmaceutical pollution of the world’s rivers

Wilkinson, J.L.; A.B. A. Boxall, D. W. Kolpin, et al. (2022) CC

PNAS 119 (8) e2113947119 | https://doi.org/10.1073/pnas.2113947119 Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, m... more