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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

Guidance note for practitioners leveraging climate-smart agriculture for peace: Insights from a bundle of interventions in Ghana

Alliance of Bioversity & CIAT; CGIAR (2024) CC

Climate change is one of the biggest crises of our time. Climate threats range from higher temperatures, heavy rainfalls and floods, erratic precipitation, droughts, desertification, and land degradation. This has negative implications on the quality and quantity of natural resources, such as land a... more

16 Days of Activism against Gender-Based Violence 25 November - 10 December 2024

UN Women (2024) CC2

TOWARDS 30 YEARS OF THE BEIJING DECLARATION AND PLATFORM FOR ACTION: UNITE TO END VIOLENCE AGAINST WOMEN Concept Note

Operational Guidance: Breastfeeding Counselling in Emergencies

Emergency Nutrition Network ENN (2021) C2

Women and children, especially pregnant girls and women, infants and young children and postpartum women, are populations that are extremely vulnerable in emergencies. Breastfeeding provides children with hydration, comfort, connection, high quality nutrition and protection against disease, shieldin... more

Guía Operativa: Asesoramiento Sobre Lactancia Materna en Situaciones de Emergencia

Emergency Nutrition Network ENN (2024) C2

El asesoramiento sobre lactancia materna es una interacción bidireccional entre un/a asesor/a con formación en lactancia materna y una o varias mujeres embarazadas, madres u otras personas cuidadoras de niños/as menores de dos años (normalmente). El proceso consiste en escuchar inquietudes, ab... more

Considerations for wastewater and environmental surveillance for monkeypox virus: interim guidance, 25 November 2024

World Health Organization WHO (2024) C_WHO

interim guidance, 25 November 2024

Multiple first-line therapies as part of the response to antimalarial drug resistance

World Health Organization WHO (2024) C_WHO

Effective malaria case management requires quick access to diagnostics and antimalarial treatments to reduce illness and death. Artemisinin-based combination therapy (ACT) has been essential to malaria treatment since 2001, as it combines artemisinin for rapid parasite reduction with a partner drug ... more

Sanitation inspections User guide

World Health Organization WHO (2024) C_WHO

Safe sanitation is essential for health, from preventing infections to improving and maintaining mental and social well-being. Lack of adequate sanitation contributes to diarrhoeal diseases, parasitic infections, and undernutrition, as well as posing significant risks and causing anxiety, especial... more

Overview of capacity building opportunities in “One Health”, internationally and with focus on Africa

Deutsche Gesellschaft für Internationale Zusammenarbeit GIZ (2022) CC2

An interdisciplinary approach to address global health challenges such as the Covid-19 pandemic, climate change, loss of biodiversity, human migration has been framed by the One Health approach. This approach is promoted at global level by the Tripartite of the World Health Organisation, the World A... more

The failure of community-based health insurance schemes in Tanzania: opening the black box of the implementation process

Kigume, R.; Maluka, S. (2021) CC2

Globally, there is increased advocacy for community-based health insurance (CBHI) schemes. Like other low and middle-income countries (LMICs), Tanzania officially established the Community Health Fund (CHF) in 2001 for rural areas; and Tiba Kwa Kadi (TIKA) for urban population since 2009. This study... more

Global update on implementation of preventive chemotherapy against neglected tropical diseases (‎NTDs)‎ in 2023 and status of donated medicines for NTDs in 2024

World Health Organization WHO (2024) C_WHO

760 WEEKLY EPIDEMIOLOGICAL RECORD, NOS. 51/52, 20 DECEMBER 2024, pp.760-769. In French and English

Essential and actionable measures for enhancing country preparedness for Viral Haemorrhagic Fever outbreaks in the WHO African Region
recommended

World Health Organization WHO (2024) C_WHO

The target audience of this document (and the associated online companion tool) includes WHO country offices in Member States of the African Region; Member States’ ministries of health and their public health emergency operation centres; relevant external assessment teams; and partners looking... more

Beyond illness: Understanding the social determinants in the life of a middle-aged Pakistani woman

World Health Organization WHO EMHJ – Vol. 30 No. 12 – 2024 (2025) C_WHO

Poverty is both a cause and a consequence of poor health, and the scarcity of resources limits access to essential health care services.

An Infographic Guide to Technology-facilitated Gender-based Violence (TFGBV)

UNFPA (2025) C2

An Infographic Guide to Technology-facilitated Gender-based Violence (TFGBV) offers a visually engaging toolkit designed to raise awareness and deepen understanding of the pervasive and harmful impact of TFGBV on women and girls in all their diversity.

Transformar cada escola da Região das Américas em uma escola promotora de saúde: Guia de implementação para instituições educacionais

Pan American Health Organization PAHO (2024) CC

As escolas realizam diariamente inúmeras atividades que ajudam a promover a saúde e o bem-estar dos alunos, famílias e comunidades. Existem evidências claras dos benefícios da abordagem das escolas promotoras da saúde (EPS), que visam melhorar os resultados globais de saúde da comunidade educ... more

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Guidance on couples HIV testing and counselling including antiretroviral therapy for treatment and prevention in serodiscordant couples: recommendations for a public health approach

World Health Organization WHO (2012) C_WHO

Taking Care of a Baby at Home After Birth: What Families Need to Do

CoreGroup; Safe the Children; USAID; et al. (2011)

This flipbook, released in Nov. 2011, contains key messages that pregnant women and their families need in order to plan care of an infant at home right after birth. It focuses on essential actions families can take both to prevent newborn death and illness and to promote healthy newborn development... more

Ethiopia Demographic and Health Survey

Central Statistical Agency [Ethiopia] and ICF International (2012) C1

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National Guidelines for the Diagnosis, Treatment and Prevention of Malaria in Kenya
recommended

Ministry of Public Health and Sanitation, Ministry of Medical Services (2010) C1

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Sensibilisation et éducation du public à la réduction des risques de catastrophe. Un guide

International Federation of Red Cross And Red Crescent Societies (2014) CC

Essential and actionable measures for enhancing country preparedness for Viral Haemorrhagic Fever outbreaks in the WHO African Region recommended

National Guidelines for the Diagnosis, Treatment and Prevention of Malaria in Kenya recommended

Essential and actionable measures for enhancing country preparedness for Viral Haemorrhagic Fever outbreaks in the WHO African Region
recommended

National Guidelines for the Diagnosis, Treatment and Prevention of Malaria in Kenya
recommended