PlosOne January 20, 2021
https://doi.org/10.1371/journal.pone.0241899
Antibiotic fixed dose combinations (FDCs) can have clinical advantages such as improving effectiveness and adherence to therapy. However, high use of potentially inappropriate FDCs has been reported, with implications for antim...icrobial resistance (AMR) and toxicity.
more
This report alerts responders to the importance of language in building trust and effective communication with people facing Ebola and other epidemics.
Ce rapport attire l’attention des intervenants sur le fait que la langue est importante pour établir la confiance avec les personnes touchées par le virus Ebola et d’autres épidémies et pour une communication efficace avec ces dernières.
1 February 2021 to 31 January 2022
On this page we provide an overview of excess mortality along with charts to explore the data. You can learn in more depth about different measures of excess mortality, their strengths and limitations, and their comparability across countries
This technical guidance aims to provide guidelines to laboratories and relevant stakeholders in the European Union (EU), European Economic Area (EEA) and other countries in the WHO European region in making decisions on establishing sequencing capacities and capabilities, in making decisions on whic...h technologies to use and/or in deciding on the role of sequencing for SARS-CoV-2 diagnostics, research, outbreak investigations and surveillance. It addresses the most used sequencing technologies and their applications and proposes a central standardisation process to analyse and report the findings of SARS-CoV-2 genetic characterisations.
more
Contact tracing is a key element of WHO’s recommended approach to control the spread of COVID-19 by breaking the chains of human-to-human transmission.
This document provides guidance to health authorities at all levels to improve the success rate of contact tracing by informing efforts with RCCE... principles, evidence and activities, and provides ready-to-use tools for professionals involved in contact-tracing efforts to inform their practices with RCCE principles and likewise improve their success rate.
more
28 Jan. 2021. L’objet de ce document est de fournir des orientations provisoires sur la sécurité biologique en laboratoire applicable à l’analyse d’échantillons cliniques issus de patients.
The International Organization for Migration (IOM) is appealing for USD 158.9 million to respond to the urgent humanitarian needs of millions of Afghans and to support recovery and resilience within the country and the region.
IOM’s Comprehensive Action Plan for Afghanistan and Neighbouring Cou...ntries aims to help the most vulnerable populations by combining humanitarian, development and peace interventions, known as the HDP nexus.
more
This publication provides managers with guidance on how to create basic HIV prevention cascades as a starting point to enhance their ability to monitor and improve their programming and to facilitate comparisons of programme effectiveness across sites.
Journal of Cancer Education
https://doi.org/10.1007/s13187-020-01935-7
Seit über einem Jahr hat die Corona-Pandemie große Veränderungen für alle Menschen in nahezu jedem Lebensbereich herbeigeführt. Geflüchtete in (Erst-) Aufnahmeeinrichtungen und Gemeinschaftsunterkünften sind in besonderem Maße von der Pandemie betroffen, da die vorgefundenen Wohnbedingungen ...einen kaum ausreichenden Schutz zulassen. Obwohl gerade die Bewohner*innen von Sammelunterkünften dem Virus stark ausgesetzt sind, hat diese Gruppe nicht ausreichend Beachtung und Schutz gefunden. Ergriffene Maßnahmen wie etwa Kollektiv- oder auch Kettenquarantänen haben die Lebensbedingungen der Bewohner*innen noch weiter erschwert, mit gravierenden Auswirkungen auf das Asylverfahren, Gesundheit, Beruf, Ausbildung und Schule und so letztendlich auch auf ihre soziale Teilhabe.
more
Herd immunity by mass vaccination offers the potential to substantially limit the continuing spread of COVID-19, but high levels of vaccine hesitancy threaten this goal. In a cross-country analysis of vaccine hesitant respondents across Latin America in January 2021, we experimentally tested how fiv...e features of mass vaccination campaigns—the vaccine’s producer, efficacy, endorser, distributor, and current population uptake rate—shifted willingness to take a COVID-19 vaccine. We find that citizens preferred Western-produced vaccines, but were highly influenced by factual information about vaccine efficacy. Vaccine hesitant individuals were more responsive to vaccine messengers with medical expertise than political, religious, or media elite endorsements. Citizen trust in foreign governments, domestic leaders, and state institutions moderated the effects of the campaign features on vaccine acceptance. These findings can help inform the design of unfolding mass inoculation campaigns.
more
The roadmap describes the actions needed to
achieve the three development goals for TB
vaccines set by the WHO:
1. A safe, effective and affordable TB vaccine
for adolescents and adults.
2. An affordable TB vaccine for neonates and
infants with improved safety and efficacy.
3. A therapeutic v...accine to improve TB
treatment outcomes
more
The larval stage of the parasite Taenia solium can encyst in the central nervous system causing neurocysticercosis, which is the main cause of acquired epilepsy in the countries in which the parasite is endemic. Endemic areas are those with the presence (or likely presence) of the full life cycle of... Taenia solium. The parasite is most prevalent in poor and vulnerable communities in which pigs roam free, open defecation is practiced, basic sanitation is deficient, and health education is absent or limited. Several tools are available for the control of Taenia solium. Preventive chemotherapy for Taenia solium taeniasis, which is directed at the adult tapeworm, is one of them. Other tools focus on pig management, pig vaccination and treatment, sanitation and hygiene, and community education. Three potential drugs—niclosamide, praziquantel, and albendazole—have been considered for use for preventive chemotherapy in Taenia solium taeniasis control programs through mass drug administration or targeted chemotherapy. In this Guideline, we provide recommendations for preventive chemotherapy in Taenia solium-endemic areas using niclosamide, praziquantel, or albendazole, including at which dose and in which population groups.
more