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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

Instruments internationaux sur l’utilisation des antimicrobiens dans les secteurs de la santé humaine, des animaux et des plantes

the Food and Agriculture Organization of the United Nations (FAO), the World Organisation for Animal Health (OIE) and the World Health Organization (WHO) (2020) C_WHO

La publication fournit une vue d'ensemble et une analyse des instruments internationaux qui établissent des normes relatives à l'utilisation des antimicrobiens dans les secteurs humain, animal et végétal, et à leur rejet dans l'environnement. L'objectif de ce document est d'identifier les instr... more

FEEDcities project A comprehensive characterization of the street food environment in cities (2019)

World Health Organization WHO (2019) C_WHO

Project protocol Introduction Ready-to-eat food sold in the street represents a global phenomenon, more common in urbanized areas, that constitutes an important dietary source in populations from low- and middle-income countries. However, research on the kind of street food offered and its composit... more

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Plan de acción mundial sobre la resistencia a los antimicrobianos

World Health Organisation (WHO) (2016) C_WHO

dades infecciosas. Los antimicrobianos eficaces son imprescindibles para las medidas preventivas y curativas, para proteger a los pacientes frente a enfermedades potencialmente mortales y para garantizar que se puedan llevar a cabo procedimientos complejos, como la cirugía y la quimioterapia, con e... more

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Política Nacional multisectorial de Salud al 2030 "Perú, País Saludable"

Ministerio de Salud - Peru (2022) CC

La salud es un estado de perfecto (completo) bienestar físico, mental y social, y no sólo la ausencia de enfermedad. El Estado Peruano reconoce a la salud como derecho fundamental, estableciendo que toda persona tiene derecho a la protección de su salud, la del medio familiar y la de la comunidad... more

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A framework for the quantification and economic valuation of health outcomes originating from health and non-health climate change mitigation and adaptation action

World Health Organization WHO (2023) C_WHO

This report presents a framework to link science, policy and practice for a comprehensive assessment of climate mitigation and adaptation investments and their impact on human health.The framework proposes to use weather and climate data to forecast health impacts over time, as well as biophysical a... more

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Lineamientos para la acción en salud mental

Ministerio de Salud - Peru (2004) CC

El presente documento tiene como objetivo brindar un conjunto de orientaciones que puedan constituirse en bases de toda la planificación de acciones en salud mental, así como para la elaboración de un nuevo Plan Nacional de Salud Mental. Para ello, en primer lugar, se parte de un Marco Conceptua... more

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Liste nationale des médicaments essentiels Haiti

Joseph, F. J.-J. Ministère de la Santé Publique et de la Population, Haiti (2012) C_WHO

Cette première édition de LNME constitue un grand pas dans la mise en oeuvre de la Politique Pharmaceutique Nationale. Le MSPP, à travers la Direction de la Pharmacie, du Médicament et de la Médecine Traditionnelle, s’engage à mettre à jour la présente Liste Nationale de Médicaments Essen... more

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USA National Action Plan for Combating Antibiotic Resistant Bacteria 2020-2025

U.S. Government (2020) C2

The National Action Plan for Combating Antibiotic-Resistant Bacteria (CARB), 2020-2025, presents coordinated, strategic actions that the United States Government will take in the next five years to improve the health and wellbeing of all Americans by changing the course of antibiotic resistance. T... more

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Guide to Prudent Use of Antimicrobial Agents in Dairy Production

International Dairy Federation (2013) C2

Antimicrobial agents play an indispensable role in animal health and welfare management. At the same time, the need for prudent use is obvious to ensure good food safety outcomes and to manage the potential risk of antimicrobial resistance. The emergence of multi-resistant bacteria is posing challen... more

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Antibiotic Resistance in Food Animals in Africa: A Systematic Review and Meta-Analysis

Founou, L.L.; D. Gyamfi Amoako, R. Carrel Founou, et al. (2015) C2

MICROBIAL DRUG RESISTANCEVolume 24, Number 5, 2018ªMary Ann Liebert, Inc.DOI: 10.1089/mdr.2017.0383 Antibiotic resistance (ABR) is a worldwide publichealth concern, with serious health, economic, and so-cietal repercussions. Its emergence is attributed to the se-lective pressure exerted by antib... more

Guidelines for the use of antibiotics in production animals: Cattle, pigs, sheep and goats

The Swedish Veterinary Association SVS (2017) C2

In 1998 the Swedish Veterinary Association decided to adopt a general policy for the use of antibiotics in animals. Since then specifi c policies for the use of antibiotics in dogs and cats have been adopted and in 2011 Guidelines for the use of Antibiotics in Production animals – Cattle and Pigs,... more

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Sierra Leone: National Strategy Plan for Combating Antimicrobial Resistance

Ministry of Health and Sanitation Sierra Leone (2018) C_WHO

Antimicrobials have been a critical public health tool since the discovery of penicillin in 1928, saving the lives of millions of people around the world. Today, however, the emergence of drug resistance is reversing the miracles of the past eighty years, with drug choices for the treatment of many ... more

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Reproductive, Maternal, Neonatal and Child Health Program Overview and Pharmaceuticals Management Training for Pharmacy Professionals. Participant Manual

Ministry of Health, Federal Democratic Republic of Ethiopia (2018) CC

The Federal Ministry of Health (FMOH) has been coordinating sector wide reforms that aim to improve equity and quality of maternal and child health services. As part of these efforts, the ministry is also exerting concerted efforts to improve availability and use of quality... more

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National Guidelines for Accreditation, Supervision and Regulation of ART Clinics in India

Ministry of Health and Family Welfare Government of India; Indian Council of Medical Research; National Academy of Medical Sciences (2005) C1

Combination file of all the documents related to the national guidelines for accreditation, supervision and regulation of ART clinics in India. Documents included: National Guidelines for Accreditation, Supervision & Regulation of ART Clinics in India | Preliminary Pages | Corrigendum | Chapter 1 ... more

Ethical considerations for use of unregistered interventions for Ebola viral disease

World Health Organization (2014)

West Africa is experiencing the largest, most severe, most complex outbreak of Ebola virus disease in history. On 11 August 2014, WHO convened a consultation where the participants concluded that in the particular context of the current Ebola outbreak in West Africa, it is ethically acceptable to of... more

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Ebola virus disease preparedness strengthening team Guinea-Bissau country visit 12–20 November 2014

World Health Organization (2014)

The main objective of this mission was to assess the level of preparedness of Guinea-Bissau in respect of the WHO consolidated checklist. The checklist helps countries to assess and test their level of readiness it is being used to identify concrete action to be taken and where countries will requir... more

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Burundi Regional Refugee Response Plan: January - December 2018

United Nations High Commissioner for Refugees (UNHCR) (2017) C1

As the Burundi refugee crisis enters its fourth year, some 430,000 Burundian refugees are being hosted across the region by the governments and people of Tanzania, Rwanda, the Democratic Republic of the Congo, and Uganda. Although the spectre of mass violence in Burundi has receded, with the politic... more

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Management of Children with Intellectual and Developmental Disability in an African Setting

Maroufou Jules Alao, Blaise Ayivi and Didier Lacombe (2012) CC

Chapter 2 in "Latest Findings in Intellectual and Developmental Disabilities Research" Edited by Üner Tan, ISBN 978-953-307-865-6, 404 pages, Publisher: InTech, Chapters published February 15, 2012 under CC BY 3.0 license | Intellectual and Developmental Disabilities presents reports on a wide rang... more

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Expanding the Roles of Nurses in Primary Health Care

Pan American Health Organization (PAHO), World Health Organization - Regional Office for the Americas (WHO) (2018) C_WHO

[Preface]. For more than forty years Primary Health Care (PHC) has been recognized as the cornerstone of an effective and responsive health system. The Alma-Ata Declaration of 1978 reaffirmed the right to the highest attainable level of health, with equity, solidarity and the right to health as its ... more