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Recommendation regarding the use of Ivermectin as a treatment for COVID-19
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Pan American Health Organization PAHO, World Health Organization WHO (2020) C_WHO
A recent study informed that ivermectin was successfully used in vitro for the treatment of SARS-CoV-2 in experimentally infected cells and two preprint publications on observational clinical studies reported the apparent utility of ivermectin to treat patients with COVID-19 needing mechanical venti... more
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COVID-19 vaccine tracker and landscape
recommended

World Health Organization WHO (2022) C_WHO
The COVID-19 vaccine tracker and landscape compiles detailed information of each COVID-19 vaccine candidate in development by closely monitoring their progress through the pipeline. The COVID-19 vaccine tracker: Provides summary tables of COVID-19 vaccine candidates in both clinical and pre-... more
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Enhancing mental health pre-service training with the mhGAP Intervention Guide: experiences and lessons learned

World Health Organization WHO (2020) C_WHO
This document was designed to inform educators, amongst others, about enhancing the pre-service curriculum with mental health Gap Action Programme Intervention Guide (mhGAP-IG) materials, which can provide future professionals with the theoretical and clinical knowledge they need to provide mental h... more
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Antigen-detection in the diagnosis of SARS-CoV-2 infection
recommended

World Health Organization WHO (2021) C_WHO
Interim guidance, 6 October 2021 Direct detection of SARS-CoV-2 viral proteins (antigens) in nasal swabs and other respiratory secretions using lateral flow immunoassays (also known as rapid diagnostic tests, RDTs) offers a faster and less expensive method to test for SARS-CoV-2 than the reference ... more
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COVID-19 Vaccine Development and Access Strategy

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1
Available in English, French, Portuguese and Arabic Successful immunization of a critical mass of the African population with one or several safe and efficacious COVID-19 vaccines.Key objectives1. Accelerate African involvement in the clinical development of a vaccine. 2. Ensur... more
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Ongoing Living Update of Potential COVID-19 Therapeutics: Summary of Rapid Systematic Reviews. Rapid Review

Pan American Health Organisation PAHO (2020) C_WHO
As of 31 October 2020 This is the tenth edition of this summary of rapid systematic reviews, which includes the results of a rapid systematic review of currently available literature. More than 200 therapeutic options or their combinations are being investigated in more than 1,700 clinical trials. I... more
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How are vaccines developed?

World Health Organization WHO (2021) C_WHO
This article is part two in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. This article focuses on the ingredients in a vaccine and the three clinical trial phases. Part three outlines the nex... more
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How does the Pfizer COVID vaccine work?

BioDigital (2020) CC
Exciting news this week with @Pfizer reporting their mRNA vaccine is 90% effective, based on their Phase III clinical trial data. Dr. Tom looks inside the virus to break down how mRNA vaccines work, and whether news this promising means we can finally relax.
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Manufacturing, safety and quality control of vaccines

World Health Organization WHO (2020) C_WHO
This document is part three in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. Part two focused on the ingredients in a vaccine and the three clinical trial phases. This document outlines the... more
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Major new lineages of SARS-CoV-2 emerge and spread in South Africa during lockdown

Tegally, H.; et al. (2020) CC
doi: https://doi.org/10.1101/2020.10.28.20221143 This article is a preprint and has not been peer-reviewed [what does this mean?]. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice.
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High global consumption of potentially inappropriate fixed dose combination antibiotics: Analysis of data from 75 countries

Bortone, B.; et al. (2021) CC
PlosOne January 20, 2021 https://doi.org/10.1371/journal.pone.0241899 Antibiotic fixed dose combinations (FDCs) can have clinical advantages such as improving effectiveness and adherence to therapy. However, high use of potentially inappropriate FDCs has been reported, with implications for antim... more
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The different types of COVID-19 vaccines

World Health Organization WHO (2020) C_WHO
This article is part four in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. Part two focused on the ingredients in a vaccine and the three clinical trial phases. Part three focused on the ste... more
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ChAdOx1-S [recombinant], COVID-19 vaccine

World Health Organization WHO (2021) C_WHO
Manufacturers: SK Bioscience Co. Ltd. [COVID-19 Vaccine (ChAdOx1-S [recombinant])] Serum Institute of India Pvt. Ltd. [COVISHIELD™, ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant)] Efficacy shown in clinical trials in participants who received the full series of vaccine (2 doses) ir... more
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Laboratory biosafety guidance related to coronavirus disease (COVID-19) , Arabic Version

World Health Organization WHO (2021) C_WHO
28 January 2021. The purpose of this document is to provide interim guidance on laboratory biosafety related to the testing of clinical specimens of patients.
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Guidelines: updated recommendations on HIV prevention, infant diagnosis, antiretroviral initiation and monitoring
recommended

World Health Organization WHO (2021) C_WHO
These guidelines provide new and updated recommendations on the use of point-of-care testing in children under 18 months of age and point-of-care tests to monitor treatment in people living with HIV; the treatment monitoring algorithm; and timing of antiretroviral therapy (ART) among people living w... more
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Updated Recommendations Onservice Delivery For The Treatment And Care Of People Living With HIV. Summary Slides
recommended

World Health Organization WHO (2021) C_WHO
These guidelines provide new and updated recommendations on the use of point-of-care testing in children under 18 months of age and point-of-care tests to monitor treatment in people living with HIV; the treatment monitoring algorithm; and timing of antiretroviral therapy (ART) among people living w... more
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Protocolo De Manejo Clínico Do Corona Vírus (Covid-19) Na Atenção Primária Á Saúde

Ministério da Saúde, Brazil (2020) CC
O objetivo deste documento é definir o papel dos serviços de APS/ESF no manejo e controle da infecção COVID-19, bem como disponibilizar os instrumentos de orientação clínica para os profissionais que atuam na porta de entrada do SUS a partir da transmissão comunitária de COVID-19 no Brasil.
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AstraZeneca ChAdOx1-S/nCoV-19 [recombinant], COVID-19 vaccine

World Health Organization WHO (2021) C_WHO
10 May 2021. Manufactureres: SK Bioscience Co. Ltd. [COVID-19 Vaccine (ChAdOx1-S [recombinant])] Serum Institute of India Pvt. Ltd. [COVISHIELD™, ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant)] The ChAdOx1-S/nCoV-19 [recombinant] vaccine is a replication-deficient adenoviral vecto... more
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Medical Ethics and Bedside Rationing in Low‐Income Countries: Challenges and Opportunities

Kapiriri, L. ResearchGate (2017) CC
Bioethics - Medical, Ethical and Legal Perspectives There’s evidence that implementing the four medical ethics principles may be challenging especially in low income country contexts with extreme resource scarcity and limited capacity to facilitate deliberations on the different ethical dilemmas.... more
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Primary Care International - Website

Primary Care International (2021) CC
PCI works with partners to strengthen the primary healthcare workforce and the systems around them, with a particular focus on NCDs. We advise and support our partners across a range of building blocks of primary care to improve the quality of care and to strengthen clinical and community-based mana... more