This short paper aims to identify key evidence gaps in our knowledge of livestock- and fisheries-linked antimicrobial resistance in the developing world, and to document on-going or planned research initiatives on this topic by key stakeholders.
The antimicrobial resistant (AMR) infections in anima...ls that are of most potential risk to human health are likely to be zoonotic pathogens transmitted through food, especially Salmonella and Campylobacter. In addition, livestock associated methicillin resistant Staphylococcus aureus (LA MRSA) and extended spectrum beta lactamase E. coli (ESBL E. coli) are emerging problems throughout the world.
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HIV infection, due to the immunosuppressant that leads, nowadays constitutes an aggravating factor of endemic tuberculosis. Tuberculosis remains a huge burden to human health, even in the early 21st century. The situation is deteriorating in many countries, particularly because of the synergy with t...he HIV epidemic and the emergence of multidrug-resistant (MDR) and extensively drug resistant (XDR) tuberculosis. The urgent development of new tools that can improve the diagnosis, prevention and/or treatment of tuberculosis and other major mycobacterium diseases depends largely on the progress of basic and applied research. Faced with this situation, there is an urgent need for effective strategies and actions to permanently solve the problem of this endemic disease whose impact is too negative on people’s lives.
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This is the first NAP on the Prevention and Containment of AMR in Kenya. It has been developed based on the National Policy on Prevention and Containment of AMR and the recommendations of the situation analysis on AMR conducted in 2011 and updated in 2016. This strategy provides a regulatory and imp...lementation framework to establish and strengthen systems to contain the emergence and spread of AMR. Implementation of this strategy will require substantial funding and high-level political commitment. Because AMR is a multidisciplinary and intersectoral issue, successful implementation of this strategy will require effective coordination and collaboration among different sectors.
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Antibiotics have been a critical public health tool since the discovery of Penicillin in 1928, saving the lives of millions of people around the world. In developing country like ours, where the burden of treatable disease is very high and access to health facilities and laboratories is difficult, a...ntibiotics have long acted as miracle drugs. Today, however, the emergence of drug
resistance in bacteria is reversing the miracles of the past eighty years, with drug choices for the treatment of many bacterial infections becoming increasingly limited, expensive, and in some cases, nonexistent. Diseases previously regarded as relatively easy to manage are much harder to treat as doctors must use “last-resort” drugs that are more costly, take longer to work
and are often unavailable or unaffordable in developing countries. Moreover, regular prescription of antibiotics, random treatment, over the counter sales, inadequate dosage, inclusion of antibiotics in animal feeds and agriculture has contributed equally to emergence of antibiotics resistance as silent epidemic within the country.
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It is intended for clinicians who are working in intensive care units (ICUs) in low and middle-income countries and managing adult and pediatric patients with severe forms of acute respiratory infection (SARI), including severe pneumonia, acute respiratory distress syndrome (ARDS), sepsis and septic... shock. It is a hands-on practical guide to be used by health care professionals involved in clinical care management during outbreaks of influenza virus (seasonal) human infection due avian influenza virus (H5N1, H7N9), MERS-CoV, COVID-19 or other emerging respiratory viral epidemics.
This course is also available in the following languages:
français - русский - Português - Bahasa Indonesia - Tiếng Việt - Español - македонски - العربية - Tetun
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Social distancing is an action taken to minimise contact with other individuals; social distancing measures comprise one category of non-pharmaceutical countermeasures (NPCs)1 aimed at reducing disease transmission and thereby also reducing pressure on health services.
This document builds upon exi...sting ECDC documents, including guidelines for the use of non-pharmaceutical measures to delay and mitigate the impact of 2019-nCoV, a rapid risk assessment: outbreak of novel coronavirus disease – 5th update, a technical report on the use of evidence in decision-making during public health emergencies, and a guidance document on community engagement for public health events caused by communicable disease threats in the EU/EEA.
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MICROBIAL DRUG RESISTANCEVolume 24, Number 5, 2018ªMary Ann Liebert, Inc.DOI: 10.1089/mdr.2017.0383
Antibiotic resistance (ABR) is a worldwide publichealth concern, with serious health, economic, and so-cietal repercussions. Its emergence is attributed to the se-lective pressure exerted by antib...iotic use in the community, hospitals, veterinary health, agriculture, aquaculture, and the environment. Additionally aggravating the situation is the fact that very few new antibiotics have recently been produced by pharmaceutical companies. It is widely acknowledged that food animals are key reservoirs of antibiotic-resistant bacteria and that antibiotic usage in this population favors the emergence, selection, and spread of resistance among animals and humans, both through zoonoses (infectious diseases trans-mitted between animals and humans) and the food chain.
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Handbook of COVID-19 Prevention and Treatment, expecting to share their invaluable practical advice and references with medical staff around the world. This handbook compared and analyzed the experience of other experts in China, and provides good reference to key departments such as hospital infect...ion management, nursing, and outpatient clinics. This handbook provides comprehensive guidelines and best practices by China's top experts for coping with COVID-19.
This handbook, provided by the First Affiliated Hospital of Zhejiang University, describes how organizations can minimize the cost while maximizing the effect of measures to manage and control the coronavirus outbreak. The handbook also discusses why hospitals and other healthcare institutions should have command centers when encountering a large-scale emergency in the context of COVID-19. This handbook also includes the following:
- Technical strategies for addressing issues during emergencies.
- Treatment methods to treat the critically ill.
- Efficient clinical decision-making support.
- Best practices for key departments like inflection management and outpatient clinics.
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O Plano Nacional de Preparação e Resposta para a doença por novo coronavírus (COVID-19) é uma ferramenta estratégica de preparação e resposta a uma potencial epidemia pelo vírus SARS-CoV-2. Este Plano tem como referencial as orientações da Organização Mundial da Saúde e do Centro Europ...eu de Prevenção e Controlo de Doenças, sendo o documento de referência nacional no que respeita ao planeamento da resposta a COVID-19. Apesar do conhecimento atualmente disponível em relação a características do SARSCoV-2 nomeadamente o seu comportamento patogénico, potencial de transmissibilidade e outros fatores determinantes não estar completo, é útil considerar, para efeitos de implementação de medidas, uma analogia entre a atual epidemia por SARS-CoV-2 e a gripe pandémica. Apesar de desafiantes, estas características tornam ainda mais premente o planeamento estruturado para diferentes cenários nesta emergência de saúde pública.
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Antibiotics have been useful in fighting infectious diseases in our country for decades, but because of the overuse and misuse of these agents, an increasing number of organisms are now resistant to them. The Philippines, like other Southeast Asian countries, has already been encountering the many c...hallenges of antimicrobial resistance (AMR) which include increasing social and economic costs and rising patient mortality. Although considered a global threat, it is already an emerging local health concern which calls for an urgent collaboration among different sectors to provide solutions addressing this growing problem.
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San Salvador, 11 de abril de 2020
En una situación de crisis como la que estamos viviendo es muy probable que los profesionales de salud que atiendan a pacientes con COVID-19 avanzado, enfrenten situaciones nuevas y complejas en que se noten con limitaciones en el actuar e incapaces para toma de... decisiones difíciles.
Además, los sistemas de salud pueden verse desbordados en capacidad de atención: los servicios de emergencia, las instalaciones de hospitalización y los servicios de medicina intensiva e intermedia. La limitación de instrumental de trabajo, medicamentos, equipos de protección puede llevar a tomar medidas no compasivas ni equitativas.
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How should humanitarian organisations prepare and respond to COVID-19 in humanitarian settings in low- and middle-income countries?
This Rapid Learning Review outlines 14 actions, insights and ideas for humanitarian actors to consider in their COVID-19 responses. It summarises and synthesises the... best available knowledge and guidance for developing a health response to COVID-19 in low- and middle-income settings as at April 2020
The paper, supported by the UN Under-Secretary-General for Humanitarian Affairs and Emergency Relief Coordinator Mark Lowcock, will be updated throughout 2020 to reflect emerging knowledge and evidence on the most effective approaches to respond to the COVID-19 Pandemic.
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The main finding is that health services have been partially or completely disrupted in many countries. More than half (53%) of the countries surveyed have partially or completely disrupted services for hypertension treatment; 49% for treatment for diabetes and diabetes-related complications; 42% fo...r cancer treatment, and 31% for cardiovascular emergencies.
Rehabilitation services have been disrupted in almost two-thirds (63%) of countries, even though rehabilitation is key to a healthy recovery following severe illness from COVID-19.
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Policy Brief 2 June 2020
The COVID-19 pandemic is a health and human crisis threatening the food security and nutrition of millions of people around the world. Hundreds of millions of people were already suffering from hunger and malnutrition before the virus hit and, unless immediate action is tak...en, we could see a global food emergency. In the longer term, the combined effects of COVID-19 itself, as well as corresponding mitigation measures and the emerging global recession could, without large-scale coordinated action, disrupt the functioning of food systems. Such disruption can result in consequences for health and nutrition of a severity and scale unseen for more than half a century.
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NHỮNG CÂN NHẮC VÀ KHUYẾN NGHỊ THIẾT THỰC CHO CÁC NHÀ LÃNH ĐẠO TÔN GIÁO VÀ CỘNG ĐỒNG TÔN GIÁO TRONG BỐI CẢNH COVID-19
Practical considerations and recommendations for religious leaders and faith-based communities in the context of COVID-19
Religious leaders, faith...-based organizations, and faith communities can play a major role in saving lives and reducing illness related to COVID-19.1 They are a primary source of support, comfort, guidance, and direct health care and social service, for the communities they serve. Religious leaders of faith-based organizations and communities of faith can share health information to protect their own members and wider communities, which may be more likely to be accepted than from other sources. They can provide pastoral and spiritual support during public health emergencies and other health challenges and can advocate for the needs of vulnerable populations.
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Este documento fornece orientações aos Estados-Membros da União Africana sobre considerações fundamentais em matéria de saúde mental e apoio psicossocial (MHPSS) em relação à pandemia de coronavírus de 2019 (COVID-19). Contém orientações úteis sobre o MHPSS para a comunidade, profissi...onais de saúde, prestadores de cuidados de saúde a populações vulneráveis e pessoas em quarentena, isolamento ou centros de tratamento(1)
(2). Estas orientações têm como objectivo proporcionar medidas práticas para reduzir o stress, a ansiedade, o estigma e as perturbações psicológicas associadas à COVID-19 e melhorar a saúde mental e o bem-estar em geral. Estas orientações podem ser utilizadas para fins de planeamento por decisores políticos e ministérios de
saúde e instituições que coordenam a resposta de emergência à resposta da COVID-19 por parte dos Estados-Membros. Pode também ser divulgada às partes interessadas.
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The consolidated guidelines are complemented by an operational handbook which is designed to assist with implementation of the WHO recommendations by Member States, technical partners and others who are involved in the management of patients with DR-TB. The WHO Operational Handbook on Tuberculosis, ...Module 4: Treatment - Drug-Resistant Tuberculosis Treatment provides practical guidance on how to put in place the recommendations at the scale needed to achieve national and global impact.
The document provides information on different aspects of care and support for TB patients. In particular, the handbook provides practical guidance on the implementation of the interventions that enable treatment adherence such as social support, treatment administration options, digital adherence technologies. The practical guidance also includes models of care for all TB patients, models of care for children and adolescents, integrated care for TB, HIV and comorbidities, engagement of private sector, managing of TB in health emergencies. This new practical handbook also includes two important chapters on health education and counselling, and palliative care for patients with TB.
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v.1 (3 de abril de 2020)
Este guia de prática clínica fornece recomendações baseadas em evidências para o controle de infecção, coleta de amostras, cuidados de suporte, tratamento medicamentoso e prevenção de complicações. As recomendações são dirigidas a todos os profissionais de sa...de que atendem os pacientes no serviço de urgência/emergência e na unidade de terapia intensiva (UTI) (médicos com especialidade em medicina de urgência, pneumologia, medicina intensiva, clínica médica, anestesiologia, infectologia, fisioterapeutas respiratórios, enfermeiros e farmacêuticos). O guia deve ser usado por tomadores de decisão e membros de entidades governamentais relacionados com o tratamento de pacientes com COVID-19 em UTI na região das Américas. Este guia não incluirá aspectos relacionados com a nutrição, fisioterapia (exceto fisioterapia respiratória) e tratamento de complicações.
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Immunization is one of the most cost-effective public health interventions to date, saving an estimated 2 to 3 million lives each year. As a direct result of immunization, the world is closer than ever to eradicating polio, and deaths from measles – a major child killer – have declined by 73 per... cent worldwide between 2000 and 2018, saving an estimated 23.2 million children’s lives. The emergence of COVID-19, however, threatens to reverse this progress by severely limiting access to life-saving vaccines.
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El Plan de Respuesta Humanitaria con Panorama de Necesidades Humanitarias Venezuela 2020 tiene por objeto proporcionar asistencia humanitaria a 4,5 millones de venezolanos y venezolanas vulnerables. Para ello, hace un llamado de $762,5 millones de dólares. El Plan se basa en la labor humanitaria qu...e se llevó a cabo en 2019 mediante tres objetivos estratégicos: prestar asistencia de emergencia para salvar vidas; asegurar los medios de vida mediante un mejor acceso a los servicios básicos; y garantizar la protección de los más vulnerables.
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