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Multi-country outbreak of mpox, External situation report #42- 9 November 2024

World Health Organisation (WHO) (2024) C_WHO

This is the 42nd situation report for the multi-country outbreak of mpox, which provides an update on the epidemiological situation of mpox in Africa (including countries in the WHO African Region and some countries in the WHO Eastern Mediterranean Region), with data as of 3 November 2024.

Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

Standards and recommendations for burns care in mass casualty incidents

World Health Organization WHO (2024) C_WHO

Caring for burns patients from the incident scene to definitive treatment can be a complex, resource-consuming process with the potential to overwhelm health system capacity.This document provides practical guidance for building capacity and capability for burns care from clinical, human resources a... more

Health Cluster Guide

World Health Organization, IASC (2020) CC

A practical handbook. This Health Cluster Guide (2nd edition, 2020) provides practical advice on how WHO, Health Cluster Coordinators and partners can work together during a humanitarian crisis to achieve the aims of reducing avoidable mortality, morbidity and disability, and restoring the delivery ... more

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Minimum Standards in Shelter, Settlement and Non-Food Items
recommended

The Sphere Project (2016) C1

Links to the Humanitarian Charter and international law

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Emergency Field Handbook

UNICEF (2005)

A Guide for UNICEF Staff

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View PDF (3248)

Prevention and Control of Noncommunicable Diseases: Guidelines for Primary Health Care in Low-Resource Settings
recommended

S. Bahendeka, S.Colagiuri, S. Mendis, et al. WHO (2012) C_WHO

Cancer, diabetes, heart disease and stroke, chronic respiratory disease

Guidelines for assessment in emergencies
recommended

ICRC and International Federation of Red Cross and Red Crescent Societies (2008)

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Standards for Maternal and Neonatal Care

WHO (2007)

Integrated Management of pregnancy and childbirth

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Philippines: Typhoon Haiyan Situation Report No. 34 (as of 28 January 2014)

OCHA (2014)

South Sudan Humanitarian Crisis Health Emergency Response Funding Proposal

WHO South Sudan (2014)

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Inter-agency Field Manual on Reproductive Health in Humanitarian Settings: 2010 Revision for Field-testing (bahasa)

Inter-agency Working Group on Reproductive Health in Crises (2010) C1

Response to Ebola Virus Disease (EVD)

Vitillo, B. Caritas Internationalis (2014)

Guidelines for planning and provision of pastoral and social support services

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Plague manual: epidemiology, distribution, surveillance and control Chapter 3-5

World Health Organization (1999) C_WHO

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Ebola virus disease preparedness strengthening team Ghana country visit 10–15 Novmeber 2014

World Health Organization (2014)

The preparedness strengthening team deployed to Ghana focused on specific objectives in order to assist the country in becoming as operationally prepared as possible to detect, investigate and report potential EVD cases effectively and safely and to mount an effective response to prevent a larger o... more

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Ebola Virus Disease Emergency Appeals (Guinea, Liberia, Sierra Leone and Global Coordination & Preparedness): Combined Ebola Operations Update No°24

International Federation of Red Cross And Red Crescent Societies (2015)

International and local/diaspora actors in the Syria response - A diverging set of systems?

Eva-Svoboda; Sara Pantuliano ODI_ Humanitarian Policy Group (2015)

This paper examines how diaspora and local organisations have responded to the crisis in Syria, how they evolved and the challenges that they face - and how international aid organisations and disapora and local groups can better work together in a new aid model.

Kenya: Transforming Health: Accelerating Attainment of Universal Health Coverage

Kenya Health Sector Strategic and Investment Plan (KNSSP) (2014) C1

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Disaster Response and Preparedness in Southern Africa - A guide to international tools and services available to governments

UN Office for the Coordination of Humanitarian Affairs (2015)

The Guide has been developed to enhance the knowledge capabilities of NDMAs and their local partners. This is accomplished by exposing them to the existing tools and services developed by the international community to facilitate effective disaster response to any scale of disaster (small, medium an... more

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GO pre-deployment training: participant handbook
recommended

World Health Organization WHO (2015) C_WHO

This is a pre-deployment training, tailored specially to the Ebola outbreak in West Africa, offered to WHO personnel, consultants, and key partners. The material covered in modules 1-4 is applicable and useful to frontline response workers, national and international. Only Module 5, which focuses on... more

Minimum Standards in Shelter, Settlement and Non-Food Items recommended

Prevention and Control of Noncommunicable Diseases: Guidelines for Primary Health Care in Low-Resource Settings recommended

Guidelines for assessment in emergencies recommended

GO pre-deployment training: participant handbook recommended

Minimum Standards in Shelter, Settlement and Non-Food Items
recommended

Prevention and Control of Noncommunicable Diseases: Guidelines for Primary Health Care in Low-Resource Settings
recommended

Guidelines for assessment in emergencies
recommended

GO pre-deployment training: participant handbook
recommended