April 2022 Volume 35 Issue 2 e00152-21
Population movements have turned Chagas disease (CD) into a global public health problem. Despite the successful implementation of subregional initiatives to control vectorial and transfusional Trypanosoma cruzi transmission in Latin American settings where t...he disease is endemic, congenital CD (cCD) remains a significant challenge. In countries where the disease is not endemic, vertical transmission plays a key role in CD expansion and is the main focus of its control. Although several health organizations provide general protocols for cCD control, its management in each geopolitical region depends on local authorities, which has resulted in a multitude of approaches. The aims of this review are to (i) describe the current global situation in CD management, with emphasis on congenital infection, and (ii) summarize the spectrum of available strategies, both official and unofficial, for cCD prevention and control in countries of endemicity and nonendemicity. From an economic point of view, the early detection and treatment of cCD are cost-effective. However, in countries where the disease is not endemic, national health policies for cCD control are nonexistent, and official regional protocols are scarce and restricted to Europe. Countries of endemicity have more protocols in place, but the implementation of diagnostic methods is hampered by economic constraints. Moreover, most protocols in both countries where the disease is endemic and those where it is not endemic have yet to incorporate recently developed technologies. The wide methodological diversity in cCD diagnostic algorithms reflects the lack of a consensus. This review may represent a first step toward the development of a common strategy, which will require the collaboration of health organizations, governments, and experts in the field.
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Arsenical monotherapies were previously very successful for treating human African trypanosomiasis (HAT).
Melarsoprol resistance emerged as early as the 1970s and was widespread by the late 1990s.
Melarsoprol resistance represents the only example of widespread drug resistance in HAT patients wher...e the genetic mechanism has been established.
The current goal of elimination of HAT as a public health problem by 2020 may be undermined by the emergence and spread of resistance to current or new drugs.
Insights into potential resistance mechanisms for current and new drugs will facilitate predictions of the likelihood of resistance and will also facilitate rational approaches to minimizing, monitoring, and tackling the future emergence of resistance.
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En 2014, le taux de mortalité maternelle au Cambodge était estimé à 170 décès pour 100 000 naissances vivantes, et le taux de mortalité néonatale à 18 décès pour 1000 naissances vivantes, selon l’enquête démographique et de santé menée au Cambodge en 2014 . Ces chiffres signifient q...ue le Cambodge a atteint les cibles des Objectifs du Millénaire pour le Développement (OMD) en 2015 pour la mortalité maternelle, la mortalité néonatale et d’autres indicateurs majeurs de la santé de la
mère, du nouveau-né et de l’enfant tels que les accouchements avec l’assistance de personnel qualifié, les accouchements dans des établissements de santé, les deuxièmes consultations de soins prénatals (ANC2+), les accouchements par césarienne et le ratio d’établissements d’orient
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Rabies is a devastating and societally important zoonotic disease, which is transmitted principally to humans through the bite of infected dogs. This acute, progressive viral encephalitis has the highest case fatality of any infectious disease and kills tens of thousands of people annually, with chi...ldren and impoverished communities being affected disproportionately.
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L'anthrax est une maladie bactérienne, causée par Bacillus anthracis, qui peut se transmettre des animaux
herbivores à l'homme par contact étroit, en mangeant de la viande d'animaux infectés, ou par contamination
environnementale. L'anthrax peut être une maladie grave nécessitant un diagnos...tic et un traitement précoces
pour éviter une issue fatale, un handicap ou une charge financière pour les patients et leurs familles. e. La
maladie affecte également le bien-être de l'homme lorsque le bétail constitue son moyen de subsistance et
un élément important de la pratique agricole. La prévention est un mayen efficace de lutte contre la maladie.
Ces observations fournissent des données sur la survenue des cas d’anthrax dans les communes de Alafia
et Douekiré dans la région de Tombouctou ; les caractéristiques des populations et la description de la zone
en appliquant une approche One Health et la vaccination du cheptel. L’objectif était de Vacciner au moins
80% du cheptel identifié des communes de Alafia dans le cercle de Tombouctou, et de Douekiré dans le
cercle Goundam contre le charbon bactéridien afin de prévenir une épizootie de pathologie infectieuse
zoonotique.
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Organisation mondiale de la Santé. (2022). Normes et recommandations techniques minimales pour les soins de santé reproductive et de santé de la mère, du nouveau-né et de l’enfant pour les équipes médicales d’urgence. Organisation mondiale de la Santé.
L'application de la technologie de santé numérique se développe rapidement en Afrique, dans
le but d'améliorer la prestation des services de santé et d'atteindre plus efficacement les
communautés éloignées et mal desservies. D'autre part, l'absence de lignes directrices et de
normes da...ns l'ensemble du continent rend difficile le partage des données de manière
significative sur l'ensemble du continent. C'est pourquoi les Centres africains de contrôle et
de prévention des maladies (Africa CDC) ont mis en place un groupe de travail composé de 24
membres afin de fournir une expertise et des conseils pour l'élaboration des lignes directrices
et des normes de l'UA en matière de HIE. Les membres du groupe de travail étaient des
experts en la matière travaillant en Afrique et au niveau international sur la collecte, l'analyse
et l'échange d'informations sur la santé. Certains de ces experts avaient participé à des
consultations antérieures sur la définition de la stratégie des systèmes d'information sur la
santé d'Afrique CDC. Un président, un coprésident et un secrétaire ont été élus pour impliquer
les membres de la tasé force dans différents groupes de travail techniques.
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Diagnosis, Case Management Prevention and Control of Leptospirosis
Background: In 2015, 5.3 million babies died in the third trimester of pregnancy and first month following birth. Progress in reducing neonatal mortality and stillbirth rates has lagged behind the substantial progress in reducing postneonatal and maternal mortality rates. The benefits to prenatal an...d neonatal health (PNH) from maternal and child health investments cannot be assumed. Methods: We analysed donor funding for PNH over the period 2003–2013. We used an exhaustive key term search followed by manual review and classification to identify official development assistance and private grant (ODA+) disbursement records in the Countdown to 2015 ODA+ Database.
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In 2014, the World Heart Federation (WHF) launched
an initiative to develop a series of Roadmaps [1e6]. Their
aim is to identify potential roadblocks on the pathway to
effective prevention, detection, and management of cardiovascular disease (CVD), along with evidence-based
solutions to overcome... them. The resulting documents
provide a framework to translate strategic intent into action
on integrating epidemiology, population, and cardiovascular outcome trial data into national plans for optimal
CVD management.
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Produced by UNICEF and IRC, with the support of the German Corporation for International Cooperation GmbH (GIZ) and the generous funding from the German Federal Ministry of Economic Cooperation and Development (BMZ), the Caring for Child Survivors of Sexual Abuse (CCS) Resource Package (Second Editi...on, 2023) is a revision of the original CCS Guidelines and associated Training (First Edition, 2012). The Second Edition offers an up-to-date global technical guidance on providing a model of quality care for children and families affected by sexual abuse in humanitarian settings. The new resources include both revised and content additions based on practitioner feedback, the most recent evidence and learning. In particular, the Guidelines aim to bring a stronger focus on gender inequality, intersectionality, as well as the connections between the best interests of the child and a survivor-centered approach.
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The Public Health Burden of Commercial Tobacco Use
The burden of disease and death from commercial tobacco* use in the United States is
overwhelmingly caused by cigarettes and other combustible tobacco products.
Chronic respiratory diseases, such as asthma and
chronic obstructive pulmonary disease, kill more than
four million people every year and affect hundreds
of millions more. These diseases erode the health
and well-being of the patients and have a negative
impact on families and societies. Women ...and
children are particularly vulnerable, especially those
in low and middle income countries, where they are
exposed on a daily basis to indoor air pollution from
solid fuels for cooking and heating. In high income
countries, tobacco is the most important risk factor
for chronic respiratory diseases, and in some of
these countries, tobacco use among women and
young people is still increasing.
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У цьому модулі описано основні принципи медичної допомоги людям, які її потребують, зокрема людям з ПНПР-розладами, а також їхнім доглядачам.
У першому підрозділі ...ього модуля подаються загальні принципи клінічної практики.
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