Since the start of the pandemic, the region has been hit by multiple natural and biological disasters. At the same time, climate change has continued to warm the world, exacerbating the impacts of many of these disasters. The *Asia-Pacific Disaster Report 2021, *also launched today, shows that the p...andemic, combined with the persistent reality of climate change, has reshaped and expanded the disaster “riskscape” in Asia and the Pacific.
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The Scientific Conceptual Framework for Land Degradation Neutrality (LDN) provides a scientific foundation for understanding, implementing and monitoring LDN. It has been designed to create a bridge between the vision and the practical implementation of LDN, by defining LDN in operational terms. The... conceptual framework is a product of the UNCCD Science-Policy Interface.
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Open access book describing tools for engaging communities in resilience strategies
Based on practical experience from participatory positive futures visioning in nine Latin American and US cities
For students and professionals of different sectors including sustainability, engineering, ec...ology and urban planning
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This study examines the effectiveness of a low-cost, targeted social media campaign to encourage COVID-19 vaccine uptake
among Arabic, Turkish and Russian speakers in Germany. The study involved a series of online experiments on the social media platform Facebook.
PLoS Neglected Tropical Diseases https://doi.org/10.1371/journal.pntd.0004762
This study shows the importance of an integrated entomological and medical surveillance for the evaluation of arboviral disease risk, which is a precondition for designing cost-effective vector control programs.
In response to the recent publication “Is onchocerciasis elimination in Africa feasible by 2025: a perspective based on lessons learnt from the African control programmes” by Dadzie et al., it is important to clarify and highlight the positive and unequivocal research and operational contributio...ns from the American experience towards the worldwide elimination of human onchocerciasis (river blindness).
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Taenia saginata is a zoonotic tapeworm that is of economic importance in countries where cattle are kept. The parasite is transmitted from human tapeworm carriers (taeniosis) to bovines (cysticercosis) by excretion of eggs or proglottids containing eggs into the environment via the stool. Bovines ca...n then ingest the eggs through contaminated feed or water. After ingestion, the eggs hatch and release oncospheres in the small intestines, where the oncospheres penetrate the intestinal wall to reach the blood circulation. This distributes them throughout the body, but primarily to muscle tissue, where they develop into cysticerci. For humans to become infected with T. saginata, raw or undercooked bovine meat or offal containing infective cysts must be consumed. Bovine cysticercosis has been associated with various environmental factors related to water sources, such as animals having access to surface water, flooding of pastures and proximity to wastewater sources.
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The guidance in this publication consists of generic definitions and methodologies for the characterization of extreme weather and climate events. This publication contribute to ensuring consistent exchange of information that underpins the WMO State of the Climate Reports, Climate Watches, climate ...change studies and other emerging applications.
The purpose of the present guidelines is not to change the practice at the national level. Instead, it provides guidance for generic definitions, which are useful in contributing to WMO State of the Climate reports, climate watches, climate change studies and other emerging applications, including the recently adopted methodology for cataloguing hazardous events (WMO-CHE). These applications require regional and/or international exchange of information on extreme events.
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The Mapping Antimicrobial Resistance and Antimicrobial Use Partnership (MAAP) project has conducted a multi-year, multi-country study that provides stark insights on the under-reported depth of the antimicrobial resistance (AMR) crisis across Africa and lays out urgent policy recommendations to addr...ess the emergency.
MAAP reviewed 819,584 AMR records from 2016-2019, from 205 laboratories across Burkina Faso, Cameroon, Eswatini, Gabon, Ghana, Kenya, Malawi, Nigeria, Senegal, Sierra Leone, Tanzania, Uganda, Zambia, and Zimbabwe. MAAP also reviewed data from 327 hospital and community pharmacies and 16 national-level AMC datasets.
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Patients with diabetes are at increased risk of developing cardiovascular disease (CVD) with its manifestations of coronary artery disease (CAD), heart failure (HF), atrial fibrillation (AF), and stroke, as well as aortic and peripheral artery diseases. In addition, diabetes is a major risk factor f...or developing chronic kidney disease (CKD), which in itself is associated with developing CVD. The combination of diabetes with these cardio-renal comorbidities enhances the risk not only for cardiovascular (CV) events but also for CV and all-cause mortality. The current European Society of Cardiology (ESC) Guidelines on the management of cardiovascular disease in patients with diabetes are designed to guide prevention and management of the manifestations of CVD in patients with diabetes based on data published until end of January 2023. Over the last decade, the results of various large cardiovascular outcome trials (CVOTs) in patients with diabetes at high CV risk with novel glucose- lowering agents, such as sodium–glucose co-transporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists (RAs), but also novel non-steroidal mineralocorticoid receptor antagonists (MRAs), such as finerenone have substantially expanded available therapeutic op-
tions, leading to numerous evidence-based recommendations for the management of this patient population.
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Long Acting Muscarinic Antagonists (LAMA) such as tiotropium and glycopyrronium are used in the management of COPD1. They have been shown to improve lung function, quality of life and exercise tolerance. They have also been associated with reduced COPD-related exacerbations, associated hospitalisati...ons and duration of hospital stay. Both the South African Thoracic Society (SATS) and Global Initiative for Chronic Obstructive Lung Disease (GOLD), guidelines recommend the use of long acting anticholinergic drugs (or long acting beta agonists) in moderate to very severe disease as defined by lung function (FEV1). The most up to date guideline, utilizing the GRADE methodology (European Respiratory Society guidelines of 2017), confirms their superiority over long acting β agonists (LABA) as monotherapy for COPD in that LAMA's have demonstrated greater efficacy in terms of exacerbation reduction, with similar safety profile.2 These recommnedations are supported by published peer-reviewed
evidence including individual papers and Cochrane reviews.
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Under-diagnosis of asthma in ‘under-fives’ may be alleviated by improved inquiry into disease history. We assessed a questionnaire-based screening tool for asthma among 614 ‘under-fives’ with severe respiratory illness in Uganda. The questionnaire responses were compared to post hoc consensu...s diagnoses by three pediatricians who were guided by study definitions that were based on medical history, physical examination findings, laboratory and radiological tests, and response to bronchodilators. Children with asthma or bronchiolitis were categorized as “asthma syndrome”. Using this approach, 253 (41.2%) had asthma syndrome. History of and present breathing difficulties and present cough and wheezing was the best performing combination of four questionnaire items [sensitivity 80.8% (95% CI 77.6–84.0); specificity 84.7% (95% CI 81.8–87.6)]. The screening tool for asthma syndrome in ‘under-fives’ may provide a simple, cheap and quick method of identifying children with possible asthma. The validity and reliability of this tool in primary care settings should be tested.
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he aetiology of asthma and allergic disease remains poorly understood, despite considerable research. The International Study of Asthma and Allergies in Childhood (ISAAC), was founded to maximize the value of epidemiological research into asthma and allergic disease, by establishing a standardized m...ethodology and facilitating international collaboration. Its specific aims are: 1) to describe the prevalence and severity of asthma, rhinitis and eczema in children living in different centres, and to make comparisons within and between countries; 2) to obtain baseline measures for assessment of future trends in the prevalence and severity of these diseases; and 3) to provide a framework for further aetiological research into genetic, lifestyle, environmental, and medical care factors affecting these diseases. The ISAAC design comprises three phases. Phase 1 uses core questionnaires designed to assess the prevalence and severity of asthma and allergic disease in defined populations. Phase 2 will investigate possible aetiological factors, particularly those suggested by the findings of Phase 1. Phase 3 will be a repetition of Phase 1 to assess trends in prevalence.
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Leitfaden für Fachpersonen des Gesundheitswesens. Grundlage des vorliegenden Handbuchs sind die aktuellen internationalen Leitlinien zur Diagnose und Behandlung der Tuberkulose.
Die vorliegende gekürzte Fassung ergänzt und aktualisiert das «Handbuch Tuberkulose 2012
Ausgabe 2015 (kommentierte Version); gemäß § 4 Abs. 2 des Gesetzes zur Verhütung und Bekämpfung von Infektionskrankheiten beim Menschen (Infektionsschutzgesetz - IfSG
In dieser Version sind die wichtigsten Änderungen zur Vorversion der Falldefinitionen markiert und durch Randnotizen erläuter...t. Zudem enthält diese Version als zusätzliche Informationen die ICD-10-Kodierungen, die den jeweiligen Übermittlungskategorien entsprechen sowie einen Vergleich mit den EU-Falldefinitionen.
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Epidemiologisches Bulletin; 14. März 2016 Nr. 10/11 ;DOI 10.17886/EpiBull-2016-014
In diesem gemeinsamen Forderungspapier formulieren der Deutsche Behindertenrat (DBR) und der Verband Entwicklungspolitik und Humanitäre Hilfe (VENRO)1 Anforderungen an die Fortschreibung der Nationalen Nachhaltigkeitsstrategie im Hinblick auf die Inklusion von Menschen mit Behinderungen
Viele der derzeit in Deutschland lebenden Älteren mit Migrationsgeschichte sind im Zielland ihrer Migration unter spezifischen Bedingungen, die mit dem Migrations- und Integrationsprozess einhergehen können, älter geworden. Allerdings ist bislang wenig über diese Gruppe bekannt. Wie wirkt sich d...as biografische Ereignis „Migration“ auf die Lebensqualität, die sozioökonomische Situation und die Gesundheit im Alter aus? Welche Unterschiede gibt es zwischen der älteren Bevölkerung mit und ohne Migrationsgeschichte? Diese Research Note gibt einen Überblick über die einschlägige Forschungsliteratur. Sie beschreibt den Forschungsstand in ausgewählten Lebensbereichen und identifiziert Erkenntnislücken sowie zukünftige Forschungsfragen an der Schnittstelle Migration und Alter(n). Darüber hinaus wird die Lebenssituation älterer Menschen mit Migrationsgeschichte nicht nur dargestellt, sondern auch zugrunde liegende Ursachen für mögliche Unterschiede in den Lebensverhältnissen im Vergleich zu Gleichaltrigen ohne Migrationsgeschichte skizziert.
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