The pharmacological management of asthma has changed considerably in recent decades, as it has come to be understood that it is a complex, heterogeneous disease with different phenotypes and endotypes. It is now clear that the goal of asthma treatment should be to achieve and maintain control of the... disease, as well as to minimize the risks (of exacerbations, disease instability, accelerated loss of lung function, and adverse treatment effects). That requires an approach that is personalized in terms of the pharmacological treatment, patient education, written action plan, training in correct inhaler use, and review of the inhaler technique at each office visit. A panel of 22 pulmonologists was invited to perform a critical review of recent evidence of pharmacological treatment of asthma and to prepare this set of recommendations, a treatment guide tailored to use in Brazil. The topics or questions related to the most significant changes in concepts, and consequently in the management of asthma in clinical practice, were chosen by a panel of experts. To formulate these recommendations, we asked each expert to perform a critical review of a topic or to respond to a question, on the basis of evidence in the literature. In a second phase, three experts discussed and structured all texts submitted by the others. That was followed by a third phase, in which all of the experts reviewed and discussed each recommendation. These recommendations, which are intended for physicians involved in the treatment of asthma, apply to asthma patients of all ages.
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Chronic respiratory diseases, such as asthma and
chronic obstructive pulmonary disease, kill more than
four million people every year and affect hundreds
of millions more. These diseases erode the health
and well-being of the patients and have a negative
impact on families and societies. Women ...and
children are particularly vulnerable, especially those
in low and middle income countries, where they are
exposed on a daily basis to indoor air pollution from
solid fuels for cooking and heating. In high income
countries, tobacco is the most important risk factor
for chronic respiratory diseases, and in some of
these countries, tobacco use among women and
young people is still increasing.
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Long-term polio vaccine security – the timely, sustained, and uninterrupted supply of suitable types of affordable, quality-assured polio vaccines – is essential in the global effort to achieve and maintain a polio free world. However, fragmented approaches and short-term planning pose considera...ble challenges to securing long-term polio vaccine security.
This framework is designed to enhance the efforts of existing structures and workstreams within the Global Polio Eradication Initiative (GPEI) and other stakeholders by improving communication and coordination on vaccine security. Ensuring vaccine security is crucial for maintaining a timely, sustained, and uninterrupted supply of affordable, quality-assured polio vaccines in the global fight to achieve and sustain a polio-free world. However, challenges such as fragmented approaches, short-term planning, a dynamic policy environment, and a diverse product pipeline present significant risks to long-term vaccine security. This framework emphasizes the need for alignment and coordination across key polio operational domains, including Poliovirus Containment, Research and Development, and Vaccine Manufacturing and Supply. It also underscores the critical role of normative frameworks and policies in shaping long-term vaccine strategies that guide these operational areas. Additionally, it highlights the importance of cross-cutting elements such as financing and access to resources, along with the integration of communication, coordination, and advocacy efforts, as essential enablers for achieving vaccine security. To secure long-term vaccine supply, it is imperative to enhance alignment and strengthen coordinated efforts across workstreams and with stakeholders, including vaccine manufacturers.
Recognizing that vaccine security is an ongoing endeavor, requiring continuous monitoring and adaptation, this framework will undergo regular updates and revisions. Initially, the management of the framework will be carried out by the GPEI Vaccine Supply Group (VSG).
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Teil II beschreibt den wissenschaftlichen Sachstand zur Inflünzapandemieplanung und Inflünzapandemiebewältigung. Hierbei wird das RKI bei der Bewertung der wissenschaftlichen Informationen durch den Expertenbeirat Inflünza beraten. Der wissenschaftliche Teil dient als fachliche Grundlage... für Entscheidungen über Massnahmen zur Vorbereitung auf den Pandemiefall sowie Massnahmen im konkreten Pandemiefall.
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Identification and initial management of cases. Clinical guidance
Der Nationale Pandemieplan besteht aus zwei Teilen. Teil I beschreibt Strukturen und Massnahmen, Teil II stellt die wissenschaftlichen Grundlagen für die Inflünzapandemieplanung und -bewältigung dar. Der vorliegende Teil I wurde von der Arbeitsgruppe Infektionsschutz der Arbeitsgemeinschaft der O...bersten Landesgesundheitsbehörden unter Mitwirkung des Bundesministeriums für Gesundheit, des Robert Koch- Instituts, des Paul-Ehrlich-Instituts und der Bundeszentrale für gesundheitliche Aufklärung erstellt. Er beschreibt die Strukturen auf Bundesund Länderebene, erörtert Massnahmen und gibt Empfehlungen zur Vorbereitung auf eine Inflünzapandemie sowie für die Pandemiebewältigung auf unterschiedlichen Planungs- und Handlungsebenen. Damit dient er als Grundlage für die Pandemieplanung im medizinischen und nichtmedizinischen Bereich und in der öffentlichen Verwaltung.
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Projekt „Monitoring des Managements von Ausbruechen durch respiratorische Erreger in Pflegeeinrichtungen"
Em 22 de janeiro de 2020, foi ativado o Centro de Operações de Emergências em Saúde Pública para o novo Coronavírus (COE – nCoV), estratégia prevista no Plano Nacional de Resposta às Emergências em Saúde Pública do Ministério da Saúde.
O novo Coronavírus (2019-nCoV) é um vírus ide...ntificado como a causa de um surto de doença respiratória detectado pela primeira vez em Wuhan, China.
Desde 2005, o Sistema Único de Saúde (SUS) está aprimorando suas capacidades de responder às emergências por síndromes respiratórias, dispondo de planos, protocolos, procedimentos e guias para identificação, monitoramento e resposta às emergências em saúde pública.
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Проект от 3 февраля 2020 г.
Эпидемиологические данные свидетельствуют о том, что 2019-нКоВ может передаваться от человека к человеку. Во время предшествующих вспышек, ...вызванных коронавирусами, в том числе коронавирусом ближневосточного респираторного синдрома (БВРС-КоВ) и коронавиру- сом тяжелого острого респираторного синдрома (ТОРС-КоВ), передача от человека к человеку чаще всего происходила капельным путем, при личном контакте и через зараженные предме- ты. Способы передачи 2019-нКоВ, по всей вероятности, те же.
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Проект – 24 января 2020 г.
WHO/2019-nCoV/Readiness/v2020.2
Временное руководство в.2 26 января 2020 г. WHO/2019-nCoV/RCCE/v2020.2
В настоящем документе представлены контрольные перечни, разработанные ВОЗ для обеспечения готовности и пр...нятия первоначальных мер реагирования в области информирования о рисках и взаимодействия с местными сообществами (ИРВС) в связи со вспышкой инфекции, вызванной новым коронавирусом 2019 г. (2019-nCoV), недавно выявленным в г. Ухань провинции Хубэй в Китае (2019-nCoV). Задача данного документа – предоставить странам практически выполнимое руководство по реализации эффективных стратегий ИРВС, которые помогут обеспечить защиту здоровья населения на раннем этапе реагирования на вспышку инфекции, вызванной nCoV.
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