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Yaws, an infectious disease caused by Treponema pallidum subspecies pertenue, is endemic in many parts of the world. A community-wide treatment program in Papua New Guinea, in which a single dose of azithromycin was administered, showed substantial ... more
Leptospirosis is an infectious disease caused by bacteria. It can lead to potentially fatal infections of the kidney, liver, brain, lung or heart.
Leishmaniasis is an infectious disease caused by protozoan parasites of the genus, Leishmania. Protozoa are microscopic, single-celled organisms. The parasites that cause the disease are transmitted to people through the bites of certain species of ... more

Progress towards Yaws eradication: successes and challenges

Handley, B. The Royal Societey of Tropical Medicine and Hygiene (2020) CC
Yaws is a chronic tropical skin disease that mainly affects children in remote, tropical and often impoverished areas. The disease presents with highly infectious lesions of the skin which can spread to the cartilage and bone. It is one of three end ... more
The available data on antimicrobial stewardship programmes in Africa are scarce. The aims of this study were to assess the implementation of an antimicrobial stewardship programme in a setting with limited infectious disease resources. Articles| ... more
WHO Fact sheets, questions and answers. Trachoma is a disease of the eye and the leading infectious cause of blindness worldwide.
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The region of Latin America and the Caribbean (LAC) has high levels of income inequality and urbanization. This leaves a large percentage of the population exposed and vulnerable to infectious disease outbreaks (1). The COVID-19 outbreak occurred su ... more
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All lyssaviruses have evolved closely with distinct natural reservoir hosts. The latter are animals species in which a pathogen of an infectious disease are maintained independently. For lyssaviruses, these are a wide range of mammalian species with ... more
The World Health Organization (WHO) Global Tuberculosis Report 2021 estimated that, in 2020, tuberculosis (TB) was the second most common infectious disease killer after coronavirus disease (COVID-19) and the 13th leading cause of death (1). Twenty- ... more
The World Health Organization (WHO) Global Tuberculosis Report 2021 estimated that, in 2020, tuberculosis (TB) was the second most common infectious disease killer after coronavirus disease (COVID-19) and the 13th leading cause of death (1). Twenty- ... more
Technical package for cardiovascular disease management in primary health care.
Research and Reports in Tropical Medicine 2022:13 25–40. Chagas disease (CD) is caused by the parasite Trypanosoma cruzi, and it is endemic in Central, South America, Mexico and the South of the United States. It is an important cause of early mortality and morbidity, and it is associated with po ... more

Laboratory diagnosis of Buruli ulcer

Portaels, F- World Health Organization WHO (2014) C_WHO
A manual for health care providers. This manual provides expert guidance on the laboratory techniques and procedures used in the diagnosis of Buruli ulcer, a disease caused by Mycobacterium ulcerans. Aimed at laboratory technicians and scientists working on this disease, the manual details the exac ... more
This document focuses on making recommendations for the diagnosis and treatment of Chagas disease, an infection caused by Trypanosoma cruzi, the protozoan agent of a systemic parasitic disease. Methodology: These clinical practice guidelines were prepared following the WHO handbook for guideline dev ... more
The World Heart Federation (WHF) has been advocating globally for stronger legislation and policy regarding cardiovascular disease (CVD) for many years. Now, as focus shifts from global to national progress, we call on members and colleagues to advocate for greater action on CVD in your local setti ... more
Effective malaria case management requires quick access to diagnostics and antimalarial treatments to reduce illness and death. Artemisinin-based combination therapy (ACT) has been essential to malaria treatment since 2001, as it combines artemisinin for rapid parasite reduction with a partner drug ... more
This fourth annual report monitors global progress towards the 2023 target for global elimination of industrially produced trans-fatty acids (TFA), highlighting achievements during the past year (October 2021 – September 2022). Countries are responding to the World Health Organization (WHO) call t ... more