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Advances in preclinical approaches to Chagas disease drug discovery

Villalta, F.; Rachakonda, G. (2019) CC

Chagas disease affects 8-10 million people worldwide, mainly in Latin America. The current therapy for Chagas disease is limited to nifurtimox and benznidazole, which are effective in treating only the acute phase of the disease but with severe side effects. Therefore, there is an unmet need for new... more

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Estimating total spending by source of funding on routine and supplementary immunisation activities in low-income and middle-income countries, 2000–17: a financial modelling study

Ikilezi, G.; A. Micah; S. Bachmeier et al. Lancet (2021) CC

Childhood immunisation is one of the most cost-effective health interventions. However, despite its known value, global access to vaccines remains far from complete. Although supply-side constraints lead to inadequate vaccine coverage in many health systems, there is no comprehensive analysis of the... more

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Education Materials for Your Patients | Cancer Handouts and Flyers

American Cancer Society (2024) C2

Website last accessed on 16.03.2024 Inform your patients about cancer, treatment, side effects, and more with these easy-to-read materials.

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Medicine Information for Primary Care in Zimbabwe

Ministry of Health and Social Welfare, Zimbabwe (2012) C1

The objective of this book is to provide health workers with easily accessible information on important aspects of the medicines commonly used at primary care level in Zimbabwe. Medicines are a crucial part of the management of most of our patients, yet many medicines are potentially dangerous if no... more

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WASH in Ebola Q&A Platform on KnowledgePoint

Wash Cluster (2014)

This page enables users to be directly linked to the technical Q&A platform in order to ask questions to Ebola Specialists in real-time. It also aims at providing up-to-date WASH guidelines, manuals and news in evolving Ebola response. Users can access the platform by clicking the link below or dire... more

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Guide national pour la prise en charge et le soutien alimentaire et nutrionnels des personnes vivant avec le VIH en Haiti
recommended

Ministère de la Santé Publique et de la Population, Haiti Fanta project (2010) CC

FANTA provided technical support to Haiti’s Ministry of Public Health and Population for the development of national guidelines and an accompanying flipchart, which provide practical solutions to nutrition problems for people living with HIV, as well as guidance on nutritionally managing the sympt... more

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After Diagnosis. Guide for Patients

American Cancer Society; Federal Ministry of Health, Ethiopia; John Hopkins Center for Communication Programs; et al. (2016)

Offers expanded content on social/emotional aspects of having cancer and how to talk with others including children; Features many direct quotes from patients, caregivers, providers; Specifies that cancer is not contagious; Corrects perception that sin or wrongdoing causes cancer; Gives... more

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Antidepressant medication in comparison with psychological treatment for moderate to severe depressive disorder
recommended

World Health Organization WHO (2015) C_WHO

Q7. SCOPING QUESTION: In adults with moderate-severe depressive disorder, what is the effectiveness and safety of antidepressant medication (ADM) in comparison with psychological treatment? The WHO mhGAP programme’s existing guidelines recommend that either structured brief psychological treatm... more

Antibiotic Stewardship - From Principles to Practice / Ebook

British Society for Antimicrobial Chemotherapy BSAC (2019) C2

This book provides significantly expanded content and experience in relation to a broader stewardship context- for example, stewardship in specific populations, different countries as well as the role of different professions in stewardship to political and media engagement. We hope this book has so... more

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Social Protection and Jobs Responses to COVID-19

Gentilini U., M. Almenfi, I. Orton (2020) C2

This second edition of the “living paper” contributes to the global knowledge on how countries are responding to the pandemic by documenting real-time actions in a key area of response – that is, social protection measures planned or implemented by governments. For the purpose of this revie... more

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Beware long-term damage to human rights and refugee rights from the coronavirus pandemic: UNHCR

UNHCR (2020) CC

The coronavirus pandemic has deepened the plight of people fleeing war, conflict and persecution. As countries battle to protect their populations and economies, fundamental norms of refugee and human rights law are at risk. “The core principles of refugee protection are being put to test – b... more

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Can ‘‘Giving Preference to My Patients’’ be Explained as a Role Related Duty in Public Health Care Systems?

Holm, S Health Care Analysis (-2011) CC

One of the most obvious ways in which to ensure impartiality in a health care system is to require impartiality of all actors in the system, i.e. to give health care professionals a duty to treat everyone impartially and to deny them the ‘right’ to give their patients preferential treatment. And... more

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An agroecological Europe by 2050: What impact on land use, trade and global food security?

Schiavo M., Le Mouël C., Poux X., et. al. (2021) C2

This Study presents the key results of a research that analyses the implications of an ambitious agroecological transition across Europe, following the TYFA scenario. Published in 2018, what it proposes by 2050 is fully aligned with the objectives that the European Farm to Fork and Biodiversity stra... more

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Donation of medicines, medical devices and IVDs -Version 3

South African Health Products Regulatory Authority (SAPHRA) SAPHRA (2020) CC

This guideline aims to improve the quality of donations and the management thereof and serve as the basis for policies of the State and other organizations in the giving and receiving of donations of medicines, medical devices and IVDs. Over the last three or four decades, there has been an enorm... more

Hesitation and Refusal Factors in Individuals' Decision-Making Processes Regarding a Coronavirus Disease 2019 Vaccination

Cerda A. A., Garcia L. Y. (2021) C2

Introduction: Considering the global prevalence of coronavirus disease 2019 (COVID-19), a vaccine is being developed to control the disease as a complementary solution to hygiene measures—and better, in social terms, than social distancing. Given that a vaccine will eventually be produced, informa... more

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Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcer

Scherr, N.; R. Bieri, S.S. Thomas, et al. (2018) CC

Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are... more

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Pathology of Schistosomiasis

Roy, S. (2022) CC

DNA studies of Egyptian mummies shows evidence of the existence of Schistosomiasis about 5000 years ago. Schistosomiasis is increasing in prevalence, affecting nearly 10% of the world’s population and ranking second only to malaria as a cause of morbidity & mortality. Schistosoma haematobium are... more

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Accelerating towards human African trypanosomiasis elimination: Issues and opportunities

Ozioko ,KU.; Okoye, CI.; Obiezue, RN.; Idika, IK.; Awudu, RA.; Ezewudo, BI.; Ezea, CO. (2019) CC

Human African trypanosomiasis (HAT) has been an alarming global public health issue. The disease affects mainly poor and marginalized people in low-resource settings and is caused by two subspecies of haemoflagellate parasite, Trypanosoma brucei and transmitted by tsetse flies. Progress made in HAT ... more

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In Control: A Practical Handbook for Professionals Working in Health Emergencies Internationally RKI

Robert Koch Institut RKI (2023) CC

The greatest risk to persons engaging in international medical emergency response is poor preparation. The In Control handbook hopes to provide a remedy. At the time of writing, we are living through the Coronavirus (COVID-19) pandemic, a health emergency that disregards physical borders, brin...gs into focus social inequalities and affects people on every continent. This shared challenge requires unprecedented measures and the collaboration of the brightest minds to support global health protection through this crisis and beyond. Healthcare infrastructures have to be strengthened, public health capacities and processes upgraded, medical countermeasures and vaccinations found and psychosocial side-effects treated. Solidarity is the normative order of the day and the human species has to collaborate to face this invisible threat. Hiding and living in fear is not an option in this interconnected world. We have both a responsibility and an opportunity to make substantial contributions to a safer, healthier and more sustainable future for us all. The existence of this handbook is an impressive example of solidarity. Over 50 authors from more than 15 institutes and organisations have come together voluntarily within a very short time to make their expertise available and enable cross-sectoral thinking. Knowledge is bundled, resources are combined, information gaps are filled. The In Control handbook is not a theoretical treatise of possible dangers, but a collection of subject-matter expertise, written by experts and practitioners who have shaped health topics over the past 20 years in the most diverse corners of the world. The Centre for International Health Protection at the Robert Koch Institute (RKI) is collaborating with its partners and investing heavily in the build-up of operational know-how and capacity to support health crisis response abroad. This is done by preparing and enabling professionals to deploy safely across the world to assist those in need. In Control addresses the multi-faceted challenges of an international deployment. Readers will find not only technical medical information, but also insights into, for example, the fragility of our environment, the cultural differences that influence risk communication or the dilemmas arising from social distancing. Legal principles are highlighted, along with ethical guidance to ensure that our actions and decisions correspond to the highest moral standards. more

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COLERA: INFORMAÇA O PARA PROMOTORES DE SAUDE ou ACTIVISTAS

World Health Organisation (WHO) (2019) C2

The PDF "COLERA: Informação para Promotores de Saúde" provides essential guidance for health promoters and activists on cholera. It explains that cholera is characterized by severe watery diarrhea, often resembling rice water, and sometimes vomiting. If not treated promptly, it can lead to death ... more

Guide national pour la prise en charge et le soutien alimentaire et nutrionnels des personnes vivant avec le VIH en Haiti recommended

Antidepressant medication in comparison with psychological treatment for moderate to severe depressive disorder recommended

Guide national pour la prise en charge et le soutien alimentaire et nutrionnels des personnes vivant avec le VIH en Haiti
recommended

Antidepressant medication in comparison with psychological treatment for moderate to severe depressive disorder
recommended