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The goal of this Global Action Plan is to articulate synergistic actions that will be required to prevent HIVDR from undermining efforts to achieve global targets on health and HIV, and to provide the most effective treatment to all people living with HIV including adults, key populations, pregnant ... more
The HIV drug resistance report 2021 summarizes findings from 38 countries that had finalized the surveys by the time of this report and shared data with WHO. Pretreatment HIVDR to non-nucleoside reverse-transcriptase inhibitors (NNRTI) can affect more than 10% of adults starting therapy and is fo ... more
Politique et plan stratégique intégré de lutte contre les maladies non transmissibles (PSIMNT) 2012-2015
Polymerase Chain Reaction (‎PCR)‎ has significantly helped in early diagnosis and commencement of specific interventions for diseases control. It also plays a critical role in understanding the disease epidemiology and unraveling the transmission dynamics of the disease. This manual intends to p ... more
This document provides a generic model that can be used for risk assessment of exposure to insecticide products applied as indoor residual sprays. It aims to harmonize the risk assessment of such insecticides for public health use in order to generate comparable data for their registering and labell ... more
Long-lasting insecticidal nets (LNs) constitute a core vector control intervention against malaria. A number of new LN products are under development and will require assessment of risks to humans. This document provides an updated generic model that can be used for the risk assessment of exposure t ... more
The plan contains the latest available evidence on the extent of insecticide resistance around the world, and puts forward a strategy for global and country levels, identifying clear roles and timelines for all stakeholders. The GPIRM also summarizes information about innovative new products being d ... more
Guidelines for the registration of microbial, botanical and semiochemical pest control agents for plant protection and public health uses. These guidelines are intended to guide pesticide regulatory authorities in the registration of microbial, botanical, and semiochemical pest control agents for p ... more
En s’appuyant sur les ODD et sur la Stratégie mondiale, ainsi que sur la Convention relative aux droits de l’enfant (CRC) et sur la Convention sur l’élimination de toutes les formes de discrimination à l’égard des femmes (CEDAW ), l’UNICEF imagine un monde où aucun enfant ne décède ... more
Dans la présente étude, le Haut-Commissariat des Nations Unies aux droits de l’homme expose les normes relatives à l’égalité et à la non discrimination à l’égard des personnes handicapées à la lumière de l’article 5 de la Convention relative aux droits des personnes handicapées. ... more
Disinfection of drinking-water supplies has been one of the most significant public health advancements of the last century with respect to reducing waterborne disease.
Although chlorine has been used as the disinfectant of choice for public drinking-water supplies for the past century, a numbe ... more
This study aimed to understand the patterns of HIV drug resistance in pregnant women in Mozambique. This might help in tailoring optimal regimens for prevention of mother to child transmission of HIV (pMTCT) and antenatal care.
Following the encouraging initial results of the pilot project, the Ministry of Health is committed to increasing access to MDR-TB diagnosis, treatment and care. An expansion plan for the programmatic management of drug-resistant TB has been developed and forms part of the Five Year National Strateg ... more
Specific measures are being taken within the National Tuberculosis Control Programme (NTP) to address the MDR TB problem through appropriate management of patients and strategies to prevent the propagation and dissemination of MDR TB.
The term "Programmatic Management of Drug Resistant TB" (PMD ... more
INT J TUBERC LUNG DIS 22(2):197–205 http://dx.doi.org/10.5588/ijtld.17.0245

Field Guide for the Management of Drug-Resistant Tuberculosis

A. Piubello The International Union Against Tuberculosis and Lung Disease (2018)
A practical tool to help health workers in the clinical and operational management of multidrug-resistant tuberculosis with special focus on the introduction, implementation and management of the nine-month treatment regimen.
Prepared as an outcome of ICMR Subcommittee on Breast Cancer |.This consensus document on management of breast cancers summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular markers and research questions. It also inter ... more
Prepared as an outcome of ICMR Subcommittee on Colorectal Cancer | Coordinated by Division of Non Communicable Diseases | This Consensus Document on Management of Colorectal Cancer summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative ca ... more
Prepared as an outcome of ICMR Subcommittee on Soft Tissue Sarcoma and Osteosarcoma | This consensus document on Management of Soft Tissue Sarcoma and Osteosarcoma summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and molecular ... more
These Guidelines are intended to provide knowledge to the treating ophthalmologists, pediatricians, ocular oncologists, pediatric oncologists, and general physicians to arrive at an early diagnosis of retinoblastoma in the settings of district hospital, in private clinics and hospitals. The guidelin ... more
As of October 2017, the global database comprised almost 30 000 records, including results from bioassays to measure phenotypic resistance, and biochemical and molecular tests for resistance mechanisms. The current report presents an overview of data on malaria vector resistance for 2010 to 2016. It ... more
This user guide is designed to provide national malaria control programmes with general information on glucose-6-phosphate dehydrogenase (G6PD) deficiency. Individuals with this condition may be at risk of adverse effects from medicines commonly used to cure Plasmodium vivax malaria, as well as from ... more

Raport mondial sur le vieillissement et la santé

Organisation mondiale de la Santé (2016) C_WHO
Catalogage à la source : Bibliothèque de l’OMS Rapport mondial sur le vieillissement et la santé. 1.Vieillissement. 2.Espérance de vie. 3.Sujet âgé. 4.Services de santé pour personnes âgées. 5.Santé mondiale. 6.Dynamique des populations. 7.Prestations des soins de santé. I.Organisation ... more
Includes a Special Report on the Financial and Personal Benefits of Early Diagnosis 2018 Alzheimer’s Disease Facts and Figures is a statistical resource for U.S. data related to Alzheimer’s disease, the most common cause of dementia. Background and context for interpretating the data are con ... more
20 February 2013 Update on 2004 Background Paper (Written by Saloni Tanna) Priority Medicines for Europe and the World "A Public Health Approach to Innovation"
Ein kompakter Ratgeber 23. aktualisierte Auflage Bei der Bewältigung der Alzheimer-Krankheit und anderer Formen der Demenz müssen viele Personen zusammenwirken: der Patient selbst, seine Angehörigen, Freunde und Bekannte, der Hausarzt und spezialisierte Ärzte, oft auch die Mitarbeiter von Be ... more

Epilepsy - A manual for Medical and Clinical Officers in Africa

International League Against Epilepsy; World Health Organization; International Bureau for Epilepsy (2002) C_WHO
J Mov Disord > Volume 11(2); 2018 > Article Review Article J Mov Disord 2018; 11(2): 53-64. Published online: May 30, 2018 DOI: https://doi.org/10.14802/jmd.17028

Developmental Disabilities

Institute of Medicine (US); Committee on Nervous System Disorders in Developing Countries; National Academy of Sciences (2001) C2
Neurological, Psychiatric, and Developmental Disorders: Meeting the Challenge in the Developing World Institute of Medicine (US) Committee on Nervous System Disorders in Developing Countries. Washington (DC): National Academies Press (US); 2001.
The present Consolidated guidelines include a comprehensive set of WHO recommendations for the treatment and care of DR-TB, derived from these WHO guidelines documents. The consolidated guidelines include policy recommendations on treatment regimens for isoniazid-resistant TB (Hr-TB) and MDR/RR-TB, ... more

Résumé analytique, conclusions et incidences stratégique

Office des Nations Unies contre la drogue et le crime (2018) C2
Rapport mondial sur les drogues 2018
This publication seeks to describe the best treatments and practices based on the scientific evidence available at the time of writing as evaluated by the authors and may change as a result of new research. Readers need to apply this knowledge to patients in accordance with the guidelines and laws o ... more
retard mental, est définie comme un arrêt du développement mental ou un développement mental incomplet, caractérisé essentiellement par une insuffisance des facultés qui déterminent le niveau global d’intelligence, c’est-à-dire les fonctions cognitives, le langage, la motricité et l ... more
Introduction Chapter A.13

Diagnosis and management of epilepsy in adults

Healthcare Improvement Scotland Scottish Intercollegiate Guideline Network (2018) C1
SIGN 143. A national clinical guideline Published May 2015, Revised 2018
This is the first global report on epilepsy summarizing the available evidence on the burden of epilepsy and the public health response required at global, regional and national levels. The reports highlights major gaps in awareness, diagnosis, treatment, and health policies through a series of a ... more
WHO today published the new edition of its Model Lists of Essential Medicines and Essential Medicines for Children, which include new treatments for various cancers, insulin analogues and new oral medicines for diabetes, new medicines to assist people who want to stop smoking, and new antimicrobials ... more
Report of the 23rd WHO Expert Committee on the selection and use of essential medicines This executive summary reports the recommendations made by the Expert Committee for the 2021 update of the WHO Model List of Essential Medicines (EML) and the Model List of Essential Medicine for Children (EMLc) ... more
Поэтому уже давно возникала мысль о том,что подробный комментарий по вопросам научных знаний и практическогоопыта, лежащих в основе политики ВОЗ по борьбе ... more
6th edition
Etude de cas

Pathophysiology of the human immunodeficiency virus

N. R. Calles; D. Evans; D.L. Terlonge Baylor International Pediatric AIDS Initiative (BIPAI) (2019) C2
Accessed: 03.09.2019
Research Article Hindawi Publishing Corporation AIDS Research and Treatment Volume 2011, Article ID 621078, 7 pages doi:10.1155/2011/621078
PLOS ONE | DOI:10.1371/journal.pone.0144057 December 14, 2015
Evaluation Report Evaluation Office
EClinicalMedicine 1 (2018) 21–27 https://doi.org/10.1016/j.eclinm.2018.06.005 2589-5370/© 2018 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). EClinicalMedicine: journal homepage: https://www.jo ... more
The aim of the operational framework is to ensure 1) accurate collection, handling, shipment and storage of specimens collected in countries implementing HIV drug resistance surveillance; and 2) the availability of quality-assured HIV genotyping laboratory services producing comparable and reliable ... more
Technical Report
L’accessibilité géographique et financière constante des médicaments essentiels de qualité, sûrs et efficaces aux populations est un objectif majeur des politiques pharmaceutiques nationales. Pour atteindre cet objectif, le Ministère de la Santé du Burkina Faso a mis en place un systèm ... more
Le cancer du col de l’utérus et le cancer du sein constituent de véritables problèmes de santé publique en raison de leur fréquence. A titre d'exemple, environ 275 000 femmes meurent chaque année d’un cancer du col de l’utérus dans le monde et la plupart de ces décès surviennent dans ... more
Training materials for healthcare workers

Introduction to ART

i-base (2018) C2
May 2018 HIV i-Base ISSN 1475-2077 www.i-Base.info Watch for out-of-date information First questions You and your doctor Resistance and adherence Treatment choices

HIV Pipeline 2018

i-base (2018) C2
htb supplement: 2018 Vol 19:(1) New drugs in development July 2018 www.i-Base.info
Plan Stratégique de Developpement des Ressources Humaines du Secteur Santé 2009-2018
Dans cette perspective, nous espérons que notre expérience pratique dans ces domaines constituera un apport aux prochaines éditions de ce guide. Et si le renforcement des systèmes de santé peut ne pas être une science exacte et que l’approche universelle n’existe pas, cette publication dé ... more

Plan national de gestion de la résistance des vecteurs du paludisme aux insecticides au Sénégal 2017-2020

Mr Moussa Balade, Dr Ibrahima Dia, Dr Mawlouth Diallo et. al. Programme national de lutte contre le paludisme - Sénégal, Ministère de la santé et de l'actoin sociale (2018) C2
Au Sénégal, la LAV repose principalement sur deux interventions majeures: la promotion de l’utilisation des Moustiquaires Imprégnées d’Insecticide à longue durée d’Action (MILDA) et l’Aspersion Intra Domiciliaire d’insecticide à effet rémanent (AID). Même si ces deux interventions ... more
Accessed Febr. 6, 2020
Accessed Febr. 6, 2020
La présente étude avait pour objectif principal de documenter la culture de l’utilisation des MI. Plus particulièrement, elle a documenté la valeur accordée aux différents moyens préventifs, en particulier la MI, les perceptions de l’utilité, du coût d’opportunité de leur utilisation ... more

Responsible use of antibiotics in aquaculture

Hernández Serrano, P. Food and Agriculture Organization (FAO) (2005) C2
In aquaculture, antibiotics have been used mainly for therapeutic purposes and as prophylactic agents. The contribution to antimicrobial resistance of antibiotics used in aquaculture is reviewed here, using a risk analysis framework. Some recommendations on responsible conduct in this context are pr ... more
To save the lives of mothers and their babies, mitigate complications, and limit the spread of disease, it is critical that recommendations are made on the prevention, treatment, and surveillance of women who are exposed to EVD, acquire EVD during pregnancy or breastfeeding, or survive EVD with ongo ... more
Antimicrobial resistance (AMR) both in human and veterinary medicine has reached alarming levels in most parts of the world and has now been recognized as a significant emerging threat to global public health and food security. In June 2015, the Food and Agriculture Organization of the United Nati ... more
A WHO guide to inform & harmonize national & international pandemic preparedness and response The main updates from the 2013 interim guidance are: Alignment with other relevant United Nations policies for crisis and emergency management, and Inclusion of the significant development in re ... more
Guide de l’OMS pour prisede décisions éclairéeset harmonisation,à l’échelle nationale et internationale, dela préparation et la réponseen cas de grippe pandémique
This briefing paper provides an overview of pre-exposure prophylaxis (PrEP) for people planning, commissioning or providing HIV prevention activities in the UK. It does this by reviewing thirty key questions about PrEP and how it might be implemented in the UK.
This guideline provides advice in regards to applications for Marketing Authorisations for antimicrobial veterinary medicinal products (VMPs) on the data required and the methodology to be used for performing an assessment of the risk to public health from antimicrobial resistance (AMR) due to use o ... more
In Vietnam, most of the examination and treatment facilities are facing with of spread of bacteria resistant to many antibiotics. The level and speed of drug resistance are increasing, at alarming level. The burden of drug resistance is increasing due to the increasing cost of treatment, prolonged t ... more
Version 9.0 Octobre 2017
L'objectif de la cartographie est d'obtenir une vision claire et précise des systèmes et politiques d'approvisionnement, de distribution et de financement des produits pharmaceutiques existants au Burkina Faso et de déterminer leur pertinence, leur cohérence et leurs forces et faiblesses en term ... more
Guide de formation à l’usage des paramédicaux Le présent guide de formation sur la prise en charge globale des personnes vivant avec le VIH est désormais à la disposition des personnels paramédicaux, des écoles et structures de formation de ces personnels dans la région africaine franco ... more
The information contained in this document, be it guidelines, recommendations, diagnostic algorithms or treatment regimens, are offered in this document in the public interest. To the best of the knowledge of the guideline writing team, the information contained in these guidelines is correct. Imple ... more
The current document is anupdate of the guidelines developed by the EUCAST subcommittee on detection of resistance mechanisms. The EUCAST Steering Committee has carried out the current update. The document has been developed mainly for routine use in clinical laboratories and doesnot cover technical ... more
The guidelines are to be used to guide the management of adults with lower respiratory tract infection (LRTI). As will be seen in the following text, this diagnosis, and the other clinical syndromes within this grouping, can be difficult to make accurately. In the absence of agreed definitions of th ... more

Situation Analysis and Recommendation: Antibiotic Use and Resistance in Tanzania

Aboud S., R. Mdegela Global Antibiotic Resistance Partnership—Tanzania Working Group (2015) C2
Antibiotics and other antimicrobial agents are invaluable life savers, particularly in resource-limited countries where infectious diseases are abundant. Both uncomplicated and severe infections are potentially curable as long as the aetiological agents are susceptible to the ... more
Jin et al. Military Medical Research (2020) 7:4 https://doi.org/10.1186/s40779-020-0233-6 Position Article und Guideline
Using the WHO model list of essential medicines to update a national essential medicines list Since 1977, WHO has been working with countries to design the package of essential medicines as an integral component of treatment within the continuum of care, developing and disseminating the Model List ... more
Interium guidance, 25 June 2021Timely and accurate diagnostic testing is an essential tool in preventing and controlling the spread of COVID-19. This document describes recommendations for national testing strategies and the use of PCR and rapid antigen tests in different transmission scenarios of t ... more
First published in 2020, this toolkit is intended for clinicians working in acute care, managing adult and paediatric patients with acute respiratory infection, including severe pneumonia, acute respiratory distress syndrome, sepsis and septic shock. The main objective is to provide key tools for us ... more
Improvements in water sanitation and hygiene (WASH) and wastewater management in all sectors are critical elements of preventing infections and reducing the spread of antimicrobial resistance (AMR) as identified in the Global Action Plan to combat AMR. Yet, at present, WASH and wastewater management ... more
While much progress has been achieved over the past year, the Region of the Americas has stubbornly remained the epicenter of the COVID-19 pandemic. PAHO is launching its 2021 COVID-19 Response Strategy and Donor Appeal to continue supporting Latin American and Caribbean countries and territories i ... more
The consolidated guidelines are complemented by an operational handbook which is designed to assist with implementation of the WHO recommendations by Member States, technical partners and others who are involved in the management of patients with DR-TB. The WHO Operational Handbook on Tuberculosis, ... more
8 July 2020
Visite au sein des Fondations Ad Lucem et Promhandicam
Ainsi, le présent profil peint le faciès épidémiologique du pays pour l’année 2015 avec un clin d’œil sur le niveau de réalisation des Objectifs du millénaire pour le développement (OMD) et un focus particulier sur l’appropriation des Objectifs de développement durable (ODD). Il e ... more
Au cours des derniers mois, la situation sécuritaire et humanitaire s'est rapidement détériorée dans les régions du Nord, du CentreNord, du Sahel, de la Boucle du Mouhoun et de l’Est du Burkina Faso. Cette dégradation a entraîné un accroissement substantiel des déplacements internes et ag ... more
Sepsis remains a leading cause of mortality and morbidity, especially during the first five days of life and in low and middle-income countries (LMIC) [1]. Hospital infection also remains a major cause of mortality in children despite progress encountered in the last decades.
Interim guidance, 6 October 2021 Direct detection of SARS-CoV-2 viral proteins (antigens) in nasal swabs and other respiratory secretions using lateral flow immunoassays (also known as rapid diagnostic tests, RDTs) offers a faster and less expensive method to test for SARS-CoV-2 than the reference ... more
This document aims to provide guidance to healthcare facilities and healthcare providers in the European Union/European Economic Area (EU/EEA) and the United Kingdom (UK) on preparedness and infection prevention and control (IPC) measures for the management of possible and confirmed cases of COVID-1 ... more
Antimalarial drug resistance has emerged as a threat to global malaria control efforts, particularly in the Greater Mekong subregion. Drawing on data collected through more than 1000 therapeutic efficacy studies as well as molecular marker studies of Plasmodium falciparum drug resistance, the Report ... more
8 January 2021 Sequencing enabled the world to rapidly identify SARS-CoV-2 and develop diagnostic tests and other tools for outbreak management. Continued genome sequencing supports the monitoring of the disease’s spread and evolution of the virus. Accelerated integration of genome sequencing int ... more
22 December 2020 The COVID-19 vaccine safety guidance manual has been developed upon recommendation and guidance of GACVS members, as well as by experts incorporating current and available information critical to all stakeholders when COVID-19 vaccines will be introduced. For ease of use, the man ... more