This document updates recommendations for HIV testing by laboratories in the United States and offers approaches for reporting test results to persons ordering HIV tests and to public health authorities. The recommended algorithm is a sequence of tests used in combination to improve the accuracy of ...the laboratory diagnosis of HIV based on testing of serum or plasma specimens. The updated recommendations also include tests for HIV antigens and HIV nucleic acid because studies from populations at high risk for HIV demonstrate that antibody testing alone might miss a considerable percentage of HIV infections detectable by virologic tests
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4th edition
The WHO Laboratory Biosafety Manual (LBM) has been in broad use at all levels of clinical and public health laboratories, and other biomedical sectors globally, serving as a de facto global standard that presents best practices and sets... trends in biosafety.
LBM encouraged countries to accept and implement basic concepts in biological safety and to develop national codes of practice for the safe handling of biological agents in laboratories within their geographical borders.
This fourth edition of the manual builds on the risk assessment framework introduced in the third edition. A thorough, evidence-based and transparent assessment of the risks allows safety measures to be balanced with the actual risk of working with biological agents on a case-by-case basis.
This novel evidence- and risk-based approach will allow optimised resource use and sustainable laboratory biosafety and biosecurity policies and practices that are relevant to their individual circumstances and priorities, enabling equitable access to clinical and public health laboratory tests and biomedical research opportunities without compromising safety.
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"Achieving, maintaining and improving accuracy, timeliness and reliability are major challenges for health laboratories. Countries worldwide committed themselves to build national capacities for the detection of, and response to, public health events of international concern when they decided to eng...age in the International Health Regulations implementation process. Only sound management of quality in health laboratories will enable countries to produce test results that the international community will trust in cases of international emergency. This handbook is intended to provide a comprehensive reference on Laboratory Quality Management System for all stakeholders in health laboratory processes, from management, to administration, to bench-work laboratorians. This handbook covers topics that are essential for quality management of a public health or clinical laboratory. They are based on both ISO 15189 and CLSI GP26-A3 documents"--Page 7.
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Due to the anticipated significant rise in VL testing occasioned by Ghana’s adaptation of 2016 ART guidelines, it has become necessary to develop this VL scale-up and operational plan to assure complete client access to laboratory monitoring towar...ds the achievement of the third 90 of the HIV care cascade. The plan will enhance VL testing, monitoring whilst improving the clinical and laboratory interface for improved client care.
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The aim of the operational framework is to ensure 1) accurate collection, handling, shipment and storage of specimens collected in countries implementing HIV drug resistance surveillance; and 2) the availability of quality-assured HIV genotyping laboratory... services producing comparable and reliable results at the national, regional and global levels.
This publication updates the WHO HIVResNet HIV drug resistance laboratory operational framework published in 2017 and reflects technical and strategic developments over the past three years.
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Rabies has an enormous impact on both agriculture and conservation biology, but its greatest burden is undeniably on public health. As such, routine methods for rapid risk assessment after human exposures to rabies as well as applications for laboratory...pan>-based surveillance, production of biologicals and management of this infectious disease are critical. Given its mandate to improve human health and control disease among its Member States, WHO has led the production of this fifth edition of Laboratory techniques in rabies.
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This document provides up-to-date guidance on laboratory studies as well as smallscale (semi-field) and large-scale field trials to assess the efficacy and determine field
application rates of new molluscicide products for control of schistosomia...sis.
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Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 23, No. 11, November 2017
O recente aumento dos casos de microcefalia e outras patologias neurológicas potencialmente associadas à infecção pelo vírus Zika provocou um aumento da procura de testes laboratoriais para detectar a infecção. Os grupos prioritários para os testes de diagnóstico devem ser
indivíduos sin...tomáticos e mulheres grávidas assintomáticas com possível exposição ao vírus Zika. O presente documento fornece orientações sobre as actuais estratégias de testes da infecção pelo vírus Zika. Este documento será revisto e actualizado à medida que surgirem novas informações.
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Los coronavirus son un grupo de virus ARN altamente diversos de la familia Coronaviridae que se dividen en
4 géneros: alfa, beta, gamma y delta, y que causan enfermedades de leves a graves en humanos y animales
(1-3). Existen coronavirus humanos endémicos como los alfacoronavirus 229E y NL63 y l...os betacoronavirus
OC43 y HKU1 que pueden causar enfermedades de tipo influenza o neumonía en humanos. Sin embargo,
tres betacoronavirus zoonóticos que pueden causar enfermedad severa en humanos han emergido: el
coronavirus del Síndrome respiratorio agudo grave (SARS-CoV), el coronavirus del Síndrome respiratorio de
Oriente Medio (MERS-CoV) y el virus de COVID-19 (SARS-CoV-2).
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Expert opinion of the European Tuberculosis Laboratory Initiative core group members for the WHO European Region.
Copenhagen, Denmark, 24–25 August 2017