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Capturing the evidence on access to essential antibiotics in refugee and migrant populations

WHO TEAM Health and migration programme, Surveillance, Prevention and Control World Health Organization WHO (2022) C_WHO

The GEHM series is an evidence-informed normative product of the WHO Health and Migration Programme to inform policy-makers on migrationrelated public health priorities. These reviews aim to respond to policy questions identified as priorities by s... more

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Making the Invisible Visible. An evidence-based analysis of gender in the regional response to the war in Ukraine.

Regional Gender Task Force CARE Evaluations (2022) C2

The escalation of the war in Ukraine began on 24 February 2022, causing thousands of civilian casualties; destroying civilian infrastructure, including hospitals, and triggering the fastest- growing displacement crisis in Europe since World War II. The demographic profile of Ukraine, combined wit... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

Supporting the routine use of evidence during the policy-making process: a WHO checklist

World Health Organisation (WHO) (2023) C_WHO

This checklist is for any organization or person supporting the routine use of evidence in the process of policy-making. Evidence-informed policy-making (EIPM) is essential for achieving the Sustai... more

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Financing the SDGs: Evidence in Four Countries

Jennifer Turner AidData at William & Mary (2019) CC

Achieving the Sustainable Development Goals (SDGs) will require the international community to mobilize significant additional financing over the next decade. Tracking and analyzing this funding is central to measuring progress and making more informed choices to direct financial flows where they wi... more

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Men and HIV: evidence-based approaches and interventions

World Health Organization WHO (2023) C_WHO

Men experience increased risk of morbidity and mortality across all ten major contributors to poor health and continue to lag behind women regarding HIV services and other health outcomes. Globally, men now account for the majority of new HIV infections. In 2022, only 72% of men living with HIV (age... more

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Reproductive health priorities: evidence from a resource tracking analysis of official development assistance in 2009 and 2010

Hsu J.; Berman P.; Mills A. The Lancet (2013) CC

nformation is scarce about the extent to which official development assistance (ODA) is spent on reproductive health to provide childbirth care; support family planning; address sexual health; and prevent, treat, and care for sexually transmitted infections, including HIV. We analysed flows of ODA t... more

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HIV/AIDS, Prevention, Testing and Treatment: Evidence from Cochrane systematic reviews

MRC South Africa; The South African Cochraine Centre; The Cochrane HIVAIDS Group (2014)

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Mobile health in Sierra Leone: Evidence and implications for health systems

the Government of Sierra Leone, the Medical Research Centre, the University of Sierra Leone, the Royal Tropical Institute (KIT), Text to Change, and MannionDaniels (2014) C1

Technical Brief

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Zika Virus and Birth Defects — Reviewing the Evidence for Causality

Sonja A. Rasmussen, M.D., Denise J. Jamieson, M.D., M.P.H., Margaret A. Honein, Ph.D., M.P.H., and Lyle R. Petersen, M.D., M.P.H. New England Journal of Medicine (2016) C3

published online April 13, 2016, DOI: 10.1056/NEJMsr1604338. Please download directly from the webpage: http://www.nejm.org/doi/pdf/10.1056/NEJMsr1604338

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HIV Epidemic Appraisals in Nigeria: Evidence for Prevention Programme Planning and Implementation: Data from the first eight States

Federal Ministry of Health, Nigeria; National Agency for the Control of Aids (NACA) (2013) C1

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Treatment of tuberculosis - Annex 3 Grade evidence profiles

World Health Organization (2017) C_WHO

Guidelines for treatment of drug-susceptible tuberculosis and patient care 2017 update

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Poverty and Risky Sexual Behaviors: Evidence from Tanzania

Silas, Joel ICF International (2013) C2

DHS Working Papers No. 88 education, wealth, mobility, employment, and media exposure

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International technical guidance on sexuality education. An evidence-informed approach.

UNESCO (2018) CC

This revised and fully updated edition of the International technical guidance on sexuality education benefits from a new review of the current evidence, and reaffirms the position of sexuality education within a framework of human rights and gen... more

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Vitamin A Supplementation Programs and Country-Level Evidence of Vitamin A Deficiency

Wirth, James P.; Petry, Nicolai and others (2017) CC

Vitamin A supplementation (VAS) programs targeted at children aged 6–59 months are implemented in many countries. By improving immune function, vitamin A (VA) reduces mortality associated with measles, diarrhea, and other illnesses. There is currently a debate regarding the relevance of VAS, but a... more

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Posttraumatic Stress Disorder: Overview of Evidence-Based Assessment and Treatment

Lancaster, C.L., Teeters, J.B., Gros, D.F., Back, S.E. Journal of Clinical Medicine (2016) CC

Abstract: Posttraumatic stress disorder (PTSD) is a chronic psychological disorder that can develop after exposure to a traumatic event. This review summarizes the literature on the epidemiology, assessment, and treatment of PTSD. We provide a review of the characteristics of PTSD along with associa... more

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New heroin-assisted treatment - Recent evidence and current practices of supervised injectable heroin treatment in Europe and beyond

J. Strang; T. Groshkova; N. Metrebian European Monitoring Centre for Drugs and Drug Addiction; Publications Office (2019) C2

EMCDDA Insights - 11 Accessed: 14.03.2019

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Slowing of the HIV Epidemic in Ukraine: Evidence from Case Reporting and Key Population Surveys, 2005–2012

C. R. Vitek; J.-I. Cakalo; Y .V. Kruglov; et al. PLOS One (2014) C2

PLOS ONE | www.plosone.org September 2014 | Volume 9 | Issue 9 | e103657

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Optimizing Clinical Trial Design to Maximize Evidence Generation in Pediatric HIV

D. Ford; R. Turner; A. Turkova; et al. JAIDS Journal of Acquired Immune Deficiency Syndromes; Ovid (2018) C2

Supplement Article www.jaids.com J Acquir Immune Defic Syndr Volume 78, Supplement 1, August 15, 2018

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WHO recommends HIV self-testing – evidence update and considerations for success

World Health Organization WHO (2019) C_WHO

Policy brief. HIV self-testing (HIVST) is a convenient and confidential option for HIV testing. In 2016 WHO recommended HIVST as a safe, accurate and effective way to reach people who may not test otherwise, including people from key populations, men and young people. Lay users can perform HIVST r... more