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A clinical case definition of post COVID-19 condition by a Delphi consensus, 6 October 2021 (Arabic Version)
recommended

World Health Organization WHO (2021) C_WHO
WHO has developed a clinical case definition of post COVID-19 condition by Delphi methodology that includes 12 domains, available for use in all settings. This first version was developed by patients, researchers and others, representing all WHO regions, with the understanding that the definition ma... more
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Clinical management of East African trypanosomiasis in South Africa: Lessons learned

Frean J., Sieling W., Pahad H. et al International Journal of Infectious Diseases (2018) C2
Background: East African trypanosomiasis is an uncommon, potentially lethal disease if not diagnosed and treated in a timely manner. South Africa, as a centre for emergency medical evacuations from much of sub-Saharan Africa, receives a high proportion of these patients, mostly tourists and expatria... more
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Algorithm for asthma diagnosis and management at Chitungwiza Central Hospital, Zimbabwe

Ndarukwa, P.; Chimbari, M.J.; Sibanda, E.N. (2020) CC2
asthma is a chronic inflammatory and a heterogeneous condition of respiratory system whose pathogenesis is linked with variable structural changes. The clinical manifestation of asthma includes attacks of breathlessness, cough, chest tightness and wheezing. Provision of basic equipment and test for ... more
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Dengue clinical management : facilitator's training manual

World Health Organization WHO (2013) C_WHO
This facilitator’s manual is designed to support the implementation of the Dengue Clinical Management training course. The guide contains specific instructions for the facilitator and provides: - a detailed description of the clinical course of dengue illness, which reflects the dynamic and sys... more
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Radiation Emergency Medical Management (REMM) - Guidance on Diagnosis and Treatment for Healthcare Providers

U.S. Department of Health & Human Services (2018) C1
What are the goals of this site? 1. Provide guidance for health care providers, primarily physicians, about clinical diagnosis and treatment of radiation injury during radiological and nuclear emergencies. 2. Provide just-in-time, evidence-based, usable information with sufficient background and co... more
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Tool for the diagnosis and care of patients with suspected arboviral diseases

Pan American Health Organization PAHO ; World Health Organization WHO (2017) C_WHO
It is Zika virus (ZIKV) that most often causes these neurological effects it appears to be the only arbovirus than can cause congenital malformations such as microcephaly. In any case, more scientific tests are needed to establish the causal relationship between the virus and this malformation (7-10... more
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Guidelines - European AIDS Clinical Society (EACS)

European AIDS Clinical Society (EACS) European AIDS Clinical Society (EACS) (2020) C2
Version 10.1_5 October 2020 These Guidelines are available in different formats: As a paper booklet, a PDF, a mobile app, and now also as a website. The 2019 version of the Guidelines introduces a new drug-drug interaction panel and now consists of six main sections, including a general overview ... more
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Antigen-detection in the diagnosis of SARS-CoV-2 infection
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World Health Organization WHO (2021) C_WHO
Interim guidance, 6 October 2021 Direct detection of SARS-CoV-2 viral proteins (antigens) in nasal swabs and other respiratory secretions using lateral flow immunoassays (also known as rapid diagnostic tests, RDTs) offers a faster and less expensive method to test for SARS-CoV-2 than the reference ... more
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Guidelines: updated recommendations on HIV prevention, infant diagnosis, antiretroviral initiation and monitoring
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World Health Organization WHO (2021) C_WHO
These guidelines provide new and updated recommendations on the use of point-of-care testing in children under 18 months of age and point-of-care tests to monitor treatment in people living with HIV; the treatment monitoring algorithm; and timing of antiretroviral therapy (ART) among people living w... more
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Chagas heart disease: An overview of diagnosis, manifestations, treatment, and care

Saraiva R.M., Mediano M.F.F., Mendes F.S. et al World Journal of Cardiology (WJC) (2021) C2
Chagas heart disease (CHD) affects approximately 30% of patients chronically infected with the protozoa Trypanosoma cruzi. CHD is classified into four stages of increasing severity according to electrocardiographic, echocardiographic, and clinical criteria. CHD presents with a myriad of clinical man... more
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First Colombian consensus on congenital Chagas and clinical approach for women of child-bearing age diagnosed with Chagas

Cucunubá Z.M., Valencia-Hernándeza C.A. , Puerta C.J. et al (2017) C2
Congenital transmission of Chagas disease has not been extensively studied in Colombia, and there are no standardized processes in the health system regarding the specific diagnosis, treatment and follow-up of this disease. To generate recommendations on congenital Chagas disease and Chagas in wom... more
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Hypertension in adults: diagnosis and management

the National Institute for Health and Care Excellence (NICE) the National Institute for Health and Care Excellence (NICE) (2023) CC
The NICE guideline "Hypertension in Adults: Diagnosis and Management" outlines recommendations for diagnosing and managing hypertension in adults over 18, including those with type 2 diabetes. It emphasizes accurate blood pressure measurement, recommending ambulatory or home monitoring to confirm di... more
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Establishing a national laboratory quality system for HIV diagnosis and monitoring in resource-limited settings: Experience from Senegal

Mbengue M.A.S., Moussa S., Papa A. D. et. al. African Journal of Laboratory Medicine (2016) C2
Senegal has adopted the World Health Organization–Joint United Nations Programme on HIV/AIDS recommended 90-90-90 targets.5 The adoption of this strategy means that the country is expected, by 2020, to have 90% of its population living with HIV diagnosed, 90% of all those diagnosed receiving susta... more
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Interim guidance for healthcare providers and Zika virus laboratory diagnosis
recommended

European Centre for Disease Prevention and Control (2016) C1
This document aims to present an algorithm for deciding whom to test and provide guidance on the laboratory tests for Zika virus infection diagnosis in order to support clinical diagnostic and case reporting through surveillance among EU Member States. The algorithm is not intended for clinical man... more
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The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies

Maguire, B.; Dahal, P.; Rashan, S.; et al. (2021) CC
PLoS Neglected Tropical diseases August 16, 2021 https://doi.org/10.1371/journal.pntd.0009697 Chagas disease, also known as American trypanosomiasis, is a neglected tropical disease transmitted by triatomine insects, first identified in 1909. Chagas disease affects approximately 6–7 million peop... more
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Leptospiral Infection, Pathogenesis and Its Diagnosis

Samrot, A.; Sean, T.; Bhavya, K.; et al. (2021) CC
Leptospirosis is a perplexing conundrum for many. In the existing literature, the pathophysiological mechanisms pertaining to leptospirosis is still not understood in full. Considered as a neglected tropical zoonotic disease, leptospirosis is culminating as a serious problem worldwide, seemingly exi... more
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European Respiratory Society guidelines for the diagnosis of asthma in adults

Renaud, L.; Imran, S.; Inigo, O., et al. European Respiratory Journal (2022) CC
Although asthma is very common, affecting 5–10% of the population, the diagnosis of asthma in adults remains a challenge in the real world, which results in both over- and under-diagnosis. A taskforce was set up by the European Respiratory Society to systematically review the literature on the dia... more
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Essential Medicines List for Management of Patients Admitted to Intensive Care Units with Suspected or Confirmed COVID-19 Diagnosis
recommended

World Health Organization WHO (2020) C_WHO
Updated 10 August 2020 This document presents an essential medicines list (EML) to manage patients in intensive care units (ICUs) with suspected or confirmed COVID-19 diagnosis, which includes active ingredients with dosage form and concentration, and are preferably in the WHO Model Lists of Essent... more
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Leishmaniasis - NIH

Clinical Info - HIV.gov (2023) C2
Website last accessed on 04.06.2023 Treatment options for Visceral Leishmaniasis in HIV-coinfected people include oral miltefosine; find additional information on diagnosis and ART treatment.