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This publication is an updated version of the Management of Tuberculosis and HIV Coinfection clinical protocol released in 2007 by the WHO Regional Office for Europe. It is intended for all health care workers involved in preventing, diagnosing, treating and caring for people living with TB and HIV ... more
Programmatic update April 2012 Executive Summary

Sexually Transmitted Diseases Treatment Guidelines, 2015

Centers for Disease Control and Prevention (2015) CC
Sixth Edition
A global Review of evidence and practice
Provide guidance to HIV care practitioners on the optimal use of antiretroviral (ARV) agents for the treatment of HIV infection in adults and adolescents.
Second Edition AIDS Medicines and diagnostics services July 2015
The TB section of the toolkit presents selected (a) programmatic output and (b) outcome and impact indicators for TB. In addition to recommended monitoring programs and measuring the outcomes and impact of TB programs, indicators for the strengthening of health systems, strengthening of community sy ... more
The main aim of these guidelines is to enable the central units of national TB and HIV/AIDS programmes to support districts to plan, coordinate and implement collaborative TB/HIV activities. These guidelines reinforce current medical understanding, that highly active antiretroviral treatment (HAART) ... more
Combination file of all the documents related to the national guidelines for accreditation, supervision and regulation of ART clinics in India. Documents included: National Guidelines for Accreditation, Supervision & Regulation of ART Clinics in India | Preliminary Pages | Corrigendum | Chapter 1 ... more

National Guidelines For the Management of HIV and AIDS

Ministry of Health and Social Welfare, Tanzania Ministry of Health and Social Welfare, Tanzania (2015) CC
5th edition.
The updated List of Essential Diagnostics contains 46 general tests that can be used for routine patient care as well as for the detection and diagnosis of a wide array of disease conditions, and 69 tests intended for the detection, diagnosis and monitoring of specific diseases. The List is divid ... more
WHO’s sentinel surveys of acquired HIV resistance to dolutegravir among people receiving dolutegravir-containing antiretroviral therapy is intended for easy and frequent implementation. Results from sentinel surveys provide insight into the prevalence and year-over-year trends of dolutegravir resi ... more
The objectives of these WHO guidelines are to provide updated evidence- based recommendations for the treatment of persons with hepatitis C infection using, where possible, all DAA-only combinations. The guidelines also provide recommendations on the preferred regimens based on a patient’s HCV gen ... more
The message contained in this publication is clear: countries need a public health system that can respond to the deliberate release of chemical and biological agents. Regrettable though this message may be, the use of poison gas in the war between Iraq and the Islamic Republic of Iran in the 19 ... more

Laboratory diagnosis of Buruli ulcer

Portaels, F- World Health Organization WHO (2014) C_WHO
A manual for health care providers. This manual provides expert guidance on the laboratory techniques and procedures used in the diagnosis of Buruli ulcer, a disease caused by Mycobacterium ulcerans. Aimed at laboratory technicians and scientists working on this disease, the manual details the exac ... more

Diagnostic de l’ulcère de Buruli au laboratoire

Portaels, F. Organisation Mondiale de la Santé (2014) C_WHO
Manuel destiné au personnel de santé. Le présent manuel est un guide spécialisé sur les techniques et les méthodes de laboratoire à utiliser pour le diagnostic de l’ulcère de Buruli, une maladie provoquée par Mycobacterium ulcerans. Destiné aux techniciens et aux scientifi ques de labora ... more
The manual is written for clinicians working at the district hospital (first-level referral care) who diagnose and manage sick adolescents and adults in resource constrained settings. It aims to support clinical reasoning, and to provide an effective clinical approach and protocols for the managemen ... more
The purpose of this pocketbook is to provide clear guidance on current best management practices for VHF across health-care facilities
This Tuberculosis guide has been developed jointly by Médecins Sans Frontières and Partners In Health. It aims at providing useful information to the clinicians and health staff for the comprehensive management of tuberculosis. Forms of susceptible and resistant tuberculosis, tuberculosis in child ... more
This Framework offers a coherent approach for eliminating tuberculosis (TB) in low-incidence countries. It is designed to guide national policy-makers and those responsible for technical aspects of the national TB response in accelerating efforts towards elimination. The document will also be inform ... more
Reach the Unreached - FIND, TREAT, CURE TB, SAVE LIVES
This guide is a resource for physicians and other health care professionals who provide care and treatment to patients with drug-resistant tuberculosis.
J. European Academy of Dermatology and Venereology, 4 August 2014
Interim Assessement Report The EMA review was started by the Agency’s Committee for Medicinal Products for Human Use (CHMP) to support decision-making by health authorities. This first interim report includes information on seven experimental medicines intended for the treatment of people infecte ... more
This clinical management manual for Ebola Viral Disease in Liberia was developed after several ETUs were established in the country following the outbreak early this year. As the outbreak evolved, it became evident that different SOPs were being used by clinicians across these treatment facilities. ... more
Up-to-date Literature review current through: Jan 2015. | This topic last updated: Jan 29, 2015.
Semi-annual Update
The recommendations in these guidelines promote the use of simple, non-invasive diagnostic tests to assess the stage of liver disease and eligibility for treatment; prioritize treatment for those with most advanced liver disease and at greatest risk of mortality; and recommend the preferred use of n ... more
MMWR Morbidity and Mortality Weekly Report December 19, 2014 / 63(50);1205-1206
NATIONAL TUBERCULOSIS AND LEPROSY PROGRAMME
Fourth Edition
COVID-19 infection affects all age groups including newborns, however, literature is scarce on the fetal and neonatal outcomes of babies exposed in-utero, especially in Africa. The objectiveof this study was to document the perinatal outcomes of COVID-19 pregnancies and del ... more
Clinical guideline for paediatric care of tuberculosis and TB-HIV co-infection
Second editon
Revised National Tuberculosis Control Programme
3rd edition
A Provisional Document. The purpose of this manual is to provide guidance to public health professionals tasked with managing a response to viral hepatitis. As every country’s needs are different with respect to its epidemiology and the current level of response, people would use this manual in di ... more
Caribbean Sub-regional Training Workshop. Introducing the new guidelines: Preparedness and Response for Chikungunya Virus Introduction in the Americas in the context of Dengue
Baseado no livro Preparación y respuesta ante la eventual introducción del virus chikungunya en las américas
J Infect Dis. (2012) 206 (suppl. 1): S61-S67 Influenza data gaps in sub-Saharan Africa include incidence, case fatality, seasonal patterns, and associations with prevalent disorders. The authors found that the burden of influenza was small during 2007–2010 in this paediatric hospital in Kenya. In ... more
Healthcare Waste Management Toolkit for Global Fund Practitioners and Policy Makers. Part B
Stellungnahme der Arbeitsgruppe AWMFLeitlinie Tuberkulose im Kindes- und Jugendalter: Diagnostik, Prävention und Therapie unter Federführung der Deutschen Gesellschaft für Pädiatrische Infektiologie. Monatsschr Kinderheilkd 2015 · 163:1287–1292 DOI 10.1007/s00112-015-0007-5 © Deutsche Gesel ... more
The goals of Ebola virus disease (EVD) surveillance during Phase 3 of the Ebola response are to promptly detect new, suspected EVD cases and deaths so as to trigger appropriate response, including rapid diagnosis, case isolation and management, contact tracing, safe burials, and the identification o ... more
The report presents current information (updated to September 2015) on candidate vaccines, therapies and medical devices for Ebola and gives an overview of completed and on-going trials.
Interim Guidance.
A number of medical problems have been reported in survivors, including mental health issues. Ebola virus may persist in some body fluids, including semen. Ebola survivors need comprehensive support for the medical and psychosocial challenges they face and also to minimize the ... more
The aim of this document is to provide interim guidance for interventions to reduce the risk of maternal Zika virus infection and to manage potential complications during pregnancy. This guidance is based on the best available research evidence and covers areas prioritized by an international, multi ... more
The use of safe and efficacious insecticides against the adult and larval populations of mosquito vectors is one of the most effective ways to rapidly interrupt transmission of Zika virus, as well as other viruses transmitted by Aedes mosquitoes such as chikungunya and dengue.
The training focuses on building the capacity of health care workers at the primary and secondary level to address and manage TB in children.
Teil II beschreibt den wissenschaftlichen Sachstand zur Inflünzapandemieplanung und Inflünza­pandemie­bewältigung. Hierbei wird das RKI bei der Bewertung der wissenschaftlichen Informationen durch den Expertenbeirat Inflünza beraten. Der wissen­schaft­liche Teil dient als fachliche Grundlage ... more
The survey aimed at evaluating the quality of selected antimalarials in six countries of sub-Saharan Africa (Cameroon, Ethiopia, Ghana, Kenya, Nigeria and the United Republic of Tanzania). These countries have been supported by WHO to strengthen their regulatory controls o ... more
The prevalence, availability, and use of antimalarial medicines (AMLs) were studied in six Cambodian provinces along the Thai-Cambodian border. The study was divided into two parts: the first looked at the quality of AMLs available in Pursat, Pailin, Battambang, Bantey Meanchey, Oddar Meanchey, and ... more
Working document from an informal consultation of experts. A Protocol for risk assessment at the field level. The purpose of document is to provide guidance on the methodology to be used for assessing, at field level, the yellow fever virus circulation in areas at risk, and is primarily intended fo ... more
Empfehlungen zur Diagnostik und Therapie nichttuberkulöser Mykobakteriosen des Deutschen Zentralkomitees zur Bekämpfung der Tuberkulose (DZK) und der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin (DGP). Schönfeld N et al. Recommendations of the German Central Committee… Pneumolo ... more
The objective of this document is to guide the preparation and implementation of national preparedness plans for the safety of substances of human origin during outbreaks of Zika virus infection, both in affected and non-affected areas.
WHO has published the first-ever guidance on the clinical management of diphtheria. The only previously available guidance was an operational protocol. The new guidance followed the rigorous process for developing guidance at WHO. It addresses the use of Diphtheria Antitoxin (DAT) in the treatmen ... more
Overcoming barriers in low- and middle-income countries For the first time, this year’s report includes information on hepatitis C diagnostics. With a focus on selected countries with diverse HCV epidemics, the report provides updates on the various dimensions of access to HCV diagnostics and pha ... more
Guidelines HIV drug resistance July 2017

HIV/AIDS Diagnostics Technology Landscape - 5th edition

Unitaid; World Health Organization (2015) C_WHO
October 2015
3rd editon
BMC Medicine201614:112 DOI: 10.1186/s12916-016-0660-0