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Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcer

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Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite ... more
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Standard treatment guidelines medicine (Respiratory Diseases) India

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Burden of disease from inadequate water, sanitation and hygiene for selected adverse health outcomes: An updated analysis with a focus on low- and middle-income countries

Prüss-Ustün A., Wolf J., Bartram J., et al. (2019) CC
Int J Hyg Environ Health. 2019 Jun; 222(5): 765–777. doi: 10.1016/j.ijheh.2019.05.004; To develop updated estimates in response to new exposure and exposure-response data of the burden of diarrhoea, r ... more
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Report - Invisible numbers: the true extent of noncommunicable diseases and what to do about them

World Health Organization (WHO) World Health Organization (WHO) (2022) C_WHO
Noncommunicable diseases (NCDs) – chief among them, cardiovascular diseases (heart disease and stroke), cancer, diabetes and chronic respiratory diseases – along with mental health, cause nearly three quarters of deaths in ... more
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Invisible numbers; The true extent of noncommunicable diseases and what to do about them 2022

World Health Organization (WHO) World Health Organization (WHO) (2022) C_WHO
Noncommunicable diseases (NCDs) – chief among them, cardiovascular diseases (heart disease and stroke), cancer, diabetes and chronic respiratory diseases – along with mental health, cause nearly three quarters of deaths in ... more
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Antibiotic Stewardship in the Hospital Environment Getting Started Guide

Best Care Always South Africa (2011) C2
The era of effective antibiotics is coming to a close. In just a few generations, many “miracle medicines”have been beaten into ineffectiveness by the bacteria they were i ... more
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Measuring the availability of human resources for health and its relationship to universal health coverage for 204 countries and territories from 1990 to 2019
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GBD 2019 Human Resources for Health Collaborators The Lancet (2022) CC
A systematic analysis for the Global Burden of Disease Study 2019. The Lancet Vol.399 Issue 10341 p.2129-2154 Human resources for health (HRH) in ... more
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COVID-19: Guidelines for case-finding, diagnosis, management and public health response in South Africa
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Bham A., J. Bhiman, F. Bongweni et al. Centre for Respiratory Diseases and Meningitis and Outbreak Response (2020) C2
The information contained in this document, be it guidelines, recommendations, diagnostic algorithms or treatment regimens, are offered in this document in the public interest. To ... more
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Global, regional, and national sex differences in the global burden of tuberculosis by HIV status, 1990–2019: results from the Global Burden of Disease Study 2019

GBD 2019 Tuberculosis Collaborators (2022) CC
Lancet Infect Dis 2022; 22: 222–4
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Guidance for the prevention of COVID-19 infections among high-risk individuals in urban settings

Caroline Favas London School of Hygiene and Tropical Medicine (2020) C2
This document provides guidance on the implementation of the shielding approach in urban areas in LICs and crisis-affected regions. It is intended for the ... more
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Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries

Hsia Y., B. R Lee, A. Versporten, et al The Lancet (2019) C2
Improving the quality of hospital antibiotic use is a major goal of WHO’s global action plan to combat antimicrobial resistance. The WHO Essential Medicines List Access, Watch, and Reserve (AWaRe) ... more
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Expanding our understanding of post COVID-19 condition: report of a WHO webinar

World Health Organization WHO (2021) C_WHO
On 9 February 2021, a first webinar entitled “Expanding our understanding of Post COVID-19 condition” was held under the auspices of WHO and in consultation with the International Severe Acute ... more
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Prevalence of Common Diseases in Indigenous People in Colombia

Bauer, H.; Mendoza, G.; Kreienbrock, L. et al. National Library of Medicine (2022) CC
The Indigenous tribe called the Wiwa lives retracted in the Sierra Nevada de Santa Marta, Colombia. Little is known about their health status and w ... more
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Clinical features and management of human monkeypox: a retrospective observational study in the UK
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H. Adler, Gould, S.; Hine, P.; et al. The Lancet (2022) CC
Cases of human monkeypox are rarely seen outside of west and central Africa. There are few data regarding viral kinetics or the duration of viral shedding and no licensed treatments. Two oral drugs, brincidofovir and tecovirimat, have been approved ... more
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Global mortality of snakebite envenoming between 1990 and 2019

Nature Communications (2022) CC
Snakebite envenoming affects millions of people worldwide annually and is a significant source of mortality. Preventing and treating the problem is complex and requires collaboration among the field ... more
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Transmission of Ebola Viruses: What We Know and What We Do Not Know

Michael T. Osterholma, Kristine A. Moorea, Nicholas S. Kelley et al. (2015)
mBio, Vol. 6 Issue 2, March/April 2015 Available evidence demonstrates that direct patient contact and contact with infectious body fluids are the primary modes for Ebola virus transmission, but this is based on a limited number of studies. In this ... more
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WHO package of essential noncommunicable (PEN) disease interventions for primary health care

World Health Organization (WHO) World Health Organization (WHO) (2020) C_WHO
The "WHO Package of Essential Noncommunicable (PEN) Disease Interventions for Primary Health Care" provides a set of cost-effective, evidence-based interventions to address noncommunicable diseases (NCDs) such as cardiovascular diseases, diabetes, c ... more
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Guidelines for the vaccination of HIV-infected adolescents and adults in South Africa

S. K. Dlamini; S. A. Madhi; R. Muloiwa; et al. Southern African Journal of HIV Medicine; AOSIS (2018) CC
Southern African Journal of HIV Medicine ISSN: (Online) 2078-6751, (Print) 1608-9693 http://www.sajhivmed.org.za Published: 23 May 2018
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A cross-country qualitative analysis of teachers’ perceptions of asthma care in sub-Saharan Africa

Naidoo, K.L.; Dladla, S.; Mphahlele, R.E. et al. npj Primary Care Respiratory Medicine (2023) CC2
Asthma is the most common chronic respiratory disease among school-going adolescents worldwide. However, the burden of severe asthma is highest in ... more
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A position statement and practical guide to the use of particulate filtering facepiece respirators (N95, FFP2, or equivalent) for South African health workers exposed to respiratory pathogens includin

Dheda, K.; et al. (2022) CC
Afr J Thoracic Crit Care Med 2021;27(4):Published online 22 October 2021. https://doi.org/10.7196/AJTCCM.2021.v27i4.173