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Publication Years
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The objective of the study was the validation and implementation of GeneXpert MTB/RIF for routine use in the rapid detection of tuberculosis and sensitivity to rifampicin in clinical samples; for this, 1592 respiratory samples were collected and ana ... more
The Updated guidelines on Management of tuberculosis in children and adolescents include new recommendations that cover diagnostic approaches for TB, shorter treatment for children with non-severe drug-susceptible TB, a new option for the treatment ... more
The practical guidance in the operational handbook aims to inform the development or revision of national policies and related implementation guidance on the management of TB in children and adolescents under programmatic circumstances and at different levels of the health system. The operational ha ... more
El agente etiológico de la tuberculosis es el Mycobacterium tuberculosis o bacilo de Koch. Se trata de un bacilo aerobio estricto, ácido-alcohol resistente, sin movilidad, de crecimiento lento y q ... more
Este documento presenta modelos de algoritmos que permiten investigar por métodos bacteriológicos a los pacientes para el diagnóstico de tuberculosis (TB), TB asociada al Virus de Inmunodeficiencia Humana (TB-HIV) y TB drogorresistente (TBDR).
In Paraguay, 1.8% of the population are indigenous people. The Maká community 29 mainly live in urbanized areas in the Central Region. This study focuses on the epidemiology 30 of tuberculosis (TB) among indigenous Maká and the non-indigenous pe ... more
Rev Panam Salud Publica. 2021;45:e74. Some characteristics of patients and healthcare providers influence treatment success in MDR-TB cases. Physicians’ and nurses’ knowledge about MDR-TB must be improved, and follow-up of MDR-TB patients who are living with HIV and of those affiliated with the ... more
El objetivo de este artículo es analizar las condiciones de acceso a servicios de salud de las personas con tuberculosis en América Latina y el Caribe (ALC), reflexionando desde la bioética sobre los aspectos de salud pública implicados. Se rea ... more
La presente guía tiene además como objetivo, ser un respaldo y no una camisa de fuerza para los médicos, pues pretendemos con ella proveer evidencia sólida respecto a los riesgos, beneficios o consecuencias que puede generar la toma de una decisión en pacientes con ... more
The Democratic Republic of Timor-Leste has the highest TB incidence rate in the South East Asian Region - 498 per 100,000, which is the seventh highest in the world. In Timor-Leste TB is the eighth most common cause of death. The salient observations are as follows: In 2018, 487 (12.5%) of the ... more
This publication is an updated version of the Management of Tuberculosis and HIV Coinfection clinical protocol released in 2007 by the WHO Regional Office for Europe. It is intended for all health care workers involved in preventing, diagnosing, tre ... more
This report has been developed, based on data provided by the TB & ORD surveillance system from across Rwanda. It provides a comprehensive picture of the occurrence and management of TB & ORD and Leprosy in Rwanda. It is structured based on the 2013-2018 Rwanda TB national strategic plan (2013-2018 ... more
The goal of this addendum is to help management and staff 
minimize the risk of TB transmission at facilities in resource limited settings in which a.) HIV-infected persons receive diagnosis, care, treatment, 
and/or support, and b.) there is a high prevalence of HIV infection, both known 
and ... more

Diagnostic atlas of intrathoracic tuberculosis in children

Robert Gie International Union Against Tuberculosis and Lung Disease (The Union) (2003)
A Guide for low income countries
A rapid situation analysis in three districts
Summary of current WHO recommendations and guidance on programmatic approaches
Policy Guidance.

Diagnostics atlas of intrathoracic tuberculosis in children

R. Gie International Union Against Tuberculosis and Lung Disease (2003)
Interim policy guidance.
Technical Brief
Towards ending tuberculosis and multidrug-resistant tuberculosis.
11-17 April 2012
This handbook builds on lessons learned from surveys implemented 2015-2017 and advice provided by the Global task force on TB patient cost surveys. It provides a standardized methodology for conducting health facility-based cross-sectional surveys to assess the direct and indirect costs incurred by ... more
The mandate of the National Tuberculosis Control Programme is to provide leadership and stewardship to accelerate intense and coordinated efforts to reduce the adult TB burden of 290 per 100,000 population recently established in the 2013 National T ... more
This study consists of a descriptive analysis of M. tuberculosis isolates from Beira Central Hospital, Mozambique, during 2014–2015, being the first report of a genotypic testing used to provide information about second line drug resistance in Moz ... more
The review’s objectives are to review progress in TB control with emphasis on DOTS strategy implementation, summarize the experience, lessons learnt and methods of work and to make recommendations for international donors, technical agencies and the Ministry of Health.

Field Guide for the Management of Drug-Resistant Tuberculosis

A. Piubello The International Union Against Tuberculosis and Lung Disease (2018)
A practical tool to help health workers in the clinical and operational management of multidrug-resistant tuberculosis with special focus on the introduction, implementation and management of the nine-month treatment regimen.
The revised guidelines contain recommendations for specific administrative, environmental controls and respiratory protection, following the assessment made by an external group of experts convened as members of the Guideline Development Group. Moreover, these guidelines focus on interventions speci ... more

Tuberculosis and HIV co-infection in Vietnam

Q.M. Trinh; H.L. Nguyen; T.N. Do; et al. International Journal of Infectious Diseases (2016) C2
International Journal of Infectious Diseases 46 (2016) 56–60

Guideline Treatment of tuberculosis in patients with HIV co-infection

Department of Health; Queensland Government (2019) C2
Version 3.0 Accessed: 24.11.2019
African Journal of Emergency Medicine Volume 11, Issue 1, March 2021, Pages 165-170
Revista Peruana de Medicina Experimental y Salud Pública 2017 Vol 34 (2) En el presente artículo se desarrolla la situación epidemiológica de la TB en el Perú al 2015, los avances en su control, de acuerdo a tres enfoques: biomédico, de gestión pública y de determinantes sociales de la salu ... more
El presente compendio normativo agrupa las principales normas que enmarcan las intervenciones del sector salud y establecen los mecanismos y procedimientos referidos a la coordinación entre el sector público y privado vinculados a la prevención y control de la ... more
Tuberculosis (‎TB)‎ is, and should be, a curable disease; however, each year significant numbers of patients acquire or develop drug-resistant TB, which has a much lower cure rate. Patients with drug-resistant TB have a high prevalence of sympto ... more
Tuberculosis (TB) is the leading cause of death from a single infectious agent even if is largely curable and preventable. In 2019 an estimated 2.9 million of the 10 million people who fell ill with TB were not diagnosed or rep ... more
Volumen 5 / Número 1 , 1025-1028 • http://www.revistabionatura.com To describe the behavior of Tuberculosis/Human Immunodeficiency Virus co-infection in a cohort of people affected by sensitive ... more
Public Health Surveillance Protocol Tuberculosis
Lancet Infect Dis 2022; 22: 222–4
Screening programmes for tuberculosis (TB) among immigrants rarely consider the heterogeneity of risk related to migrants’ country of origin. We assess the performance of a large screening programme in asylum seekers by analysing (i) the differen ... more
Tuberculosis continues to represent a severe public health problem in the Region of the Americas, even more so in the case of indigenous peoples, whose TB incidence is much higher than that of the general population. To achieve ... more
Health Policy and Planning, Volume 35, Issue 1, February 2020, Pages 47–57, https://doi.org/10.1093/heapol/czz122 Colombia has an underreporting of 30% of the total cases, according to World Health Organization (WHO) estimations. In 2016, successful tub ... more
Three classess of tests are now recommended in the latest consolidated guideles on tests for tuberculosis infection. It includes for the first-time a new class of Mycobacterium tuberculosis antigen- ... more
The Practical manual on laboratory strengthening, 2022 update provides practical guidance on implementation of WHO recommendations and best practices for TB laboratory strengthening. It is an updated version of the GLI Practical Guide to Laboratory Strengthening published in 2017 and provides the la ... more
This brief update on tuberculosis (TB) in the African region covers the state of TB in the WHO African region, strategic priorities and targets and the impact of COVID-19 on essential services. This is followed by key figures for the region, the rol ... more
People affected by impairments and disabilities associated with TB are even more likely to belong to marginalized segments of society and are more likely to have their human rights unprotected. The challenges faced by people affected by TB include the consequences of impairment and disability associ ... more
Undernutrition increases the risk of tuberculosis (TB) and in turn TB can lead to malnutrition. Undernutrition is therefore highly prevalent among people with TB. It has been demonstrated that undernutrition is a risk factor for progression from TB ... more

Guidelines for Clinical and Operational Management of Drug-Resistant Tuberculosis

José A. Caminero International Union Against Tuberculosis and Lung Disease (The Union) (2013)
2nd edition. Like the original, this second edition of the guidance aims to inform the revision of existing national guidelines and standards for managing Tuberculosis (TB), many of which include guidance on children. It includes recommendations, b ... more
A technical guide for sputum smear microscopy, initiated by the International Union against Tuberculosis, is designed to be an easy to use reference standard for the collection, storage and transport of sputum specimens and for the examination of sp ... more

A Framework for Integrating Childhood Tuberculosis into Community-based Child Health Care

Detjen A, Gnanashanmugam D, Talens A International Union Against Tuberculosis and Lung Disease (The Union), CORE Group (2013) C_WHO
3rd edition.

Prevalence of drug-resistant tuberculosis in Nigeria: A systematic review and metaanalysis

C. C. Onyedum, I. Alobu, K. N. Ukwaja PLOS One; O. Neyrolles (Institut de Pharmacologie et de Biologoie Structurale) (2017) CC
PLoS ONE 12(7): e0180996. https://doi.org/10.1371/journal.pone.0180996
Working Document, September 2017

Finding the Missing Tuberculosis Patients

D. P. Chin, C. L. Hanson The Journal of Infectious Disease; IDSA; Oxford, et al. (2017) C2
Supplement article The Journal of Infectious Diseases® 2017;216(S7):S675–8 DOI: 10.1093/infdis/jix368 Finding the Missing Tuberculosis Patients • JID 2017:216 (Suppl 7) • S675 Downloaded from https://academic.oup.com/jid/article-abs ... more
World's largest Science, Technology & Medicine Open Access book publisher Chapter 7 from the book People's Movements in the 21st Century - Risks, Challenges and Benefits

El control de la Tuberculosis en prisones

A. Bone; A. Aerts, M. Grzemska Organizaición Mundial de la Salud; Comité internacional de la Cruz roja (2000) C_WHO
Manual para directores de programas
Literature Review on TB Control in Prisons 11/18/2008
Rev Esp Sanid Penit 2012; 14: 11-16 11
Review Article: Journal of Nutritional Health & Food Science Vitamin Deficiency and Tuberculosis: Need for Urgent Clinical Page 1- 6
Review Article: The American Journal of the Medical Sciences 2011;341(6):493–498.]
Improving the management of childhood tuberculosis within national tuberculosis programmes: research priorities based on a literature review WHO/HTM/TB/2007.381, 07.02
First report of a demonstration project
An in-depth analysis of the health-seeking behaviour of patients and health system response in seven countries of the Eastern Mediterranean Region
One key aim of tuberculosis (TB) prevention and care is to render them more people-centred, which means further boosting and improving ambulatory care models across the countries of Eastern Europe and central Asia. This note is intended to remind in ... more
This is an update of a seven-year TB and Leprosy national strategic plan (TBL-NSP), which extends from 2013 to 2020. The update focuses on the plan covering from 2017-20 and is based on the 2017 external mid-term programme review key findings and recommendations; the global and national End TB strat ... more
braz j infect dis. 2014;18(5):491–495 http://dx.doi.org/10.1016/j.bjid.2014.02.004 1413-8670/© 2014 Elsevier Editora Ltda. Este é um artigo Open Access sob a licença de CC BY-NC-ND
The consolidated guidelines are complemented by an operational handbook which is designed to assist with implementation of the WHO recommendations by Member States, technical partners and others who are involved in the management of patients with DR-TB. The WHO Operational Handbook on ... more
These guidelines group all recommendations on TB care and support in one document and are complemented by an operational handbook. The guidelines are to be used primarily by national TB programmes, or their equivalents in Ministries of Health, stakeholders and technical organizations working on ... more
Rev Panam Salud Publica. 2020;44:e153. Este analisis publicada de la Revista Panamericana de Salud Pública determina el comportamiento de los indicadores de incidencia de tuberculosis (TB) y número de muertes por TB en el marco de la meta 3 ... more
N Engl J Med 2022; 386:911-922, DOI: 10.1056/NEJMoa2104535 Four months of antituberculosis treatment was noninferior to 6 months of treatment in children with drug-susceptible, nonsevere, smear-negative tuberculosis (SHINE Study)
Third edition.
РУКОВОДСТВО ДЛЯ АКТИВИСТОВ ПО ИНСТРУМЕНТАМ ДЛЯ ДИАГНОСТИКИ ТУБЕРКУЛЕЗА ЯНВАРЬ.