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A century after its discovery, Chagas' disease still represents a major public health challenge in Latin America. Moreover, because of growing population movements, an increasing number of cases of imported Chagas'
...
disease have now been detected in non-endemic areas, such as North America and some European countries. This parasitic zoonosis, caused by Trypanosoma cruzi, is transmitted to humans by infected Triatominae insects, or occasionally by non-vectorial mechanisms, such as blood transfusion, mother to fetus, or oral ingestion of materials contaminated with parasites. Following the acute phase of the infection, untreated individuals enter a chronic phase that is initially asymptomatic or clinically unapparent. Usually, a few decades later, 40-50% of patients develop progressive cardiomyopathy and/or motility disturbances of the oesophagus and colon. In the last decades several interventions targeting primary, secondary and tertiary prevention of Chagas' disease have been attempted. While control of both vectorial and blood transfusion transmission of T cruzi (primary prevention) has been successful in many regions of Latin America, early detection and aetiological treatment of asymptomatic subjects with Chagas' disease (secondary prevention) have been largely underutilised. At the same time, in patients with established chronic disease, several pharmacological and non-pharmacological interventions are currently available and have been increasingly used with the intention of preventing or delaying complications of the disease (tertiary prevention). In this review we discuss in detail each of these issues.
more
ECDC Technical Report
In line with ECDC’s recommendations provided in the ’Risk Assessment of HTLV-1/2 transmission by tissue/cell transplantation’ dated 14 March 2012, this Directive replaces the term ‘incidence’ with ‘prevalence’ in the description of endemic areas of HTLV-1/2 i ... nfection. According to the new requirements ‘HTLV-1 antibody testing must be performed for donors living in, or originating from high-prevalence areas or with sexual partners originating from those areas or where the donor’s parents originate from those areas’ and this applies to both donors of non-reproductive tissues and cells and reproductive cells.
ECDC contracted experts from the Institut Pasteur in Paris to systematically review the published evidence on the distribution of HTLV-1 infection prevalence throughout the world and to identify high-prevalence countries and areas. more
In line with ECDC’s recommendations provided in the ’Risk Assessment of HTLV-1/2 transmission by tissue/cell transplantation’ dated 14 March 2012, this Directive replaces the term ‘incidence’ with ‘prevalence’ in the description of endemic areas of HTLV-1/2 i ... nfection. According to the new requirements ‘HTLV-1 antibody testing must be performed for donors living in, or originating from high-prevalence areas or with sexual partners originating from those areas or where the donor’s parents originate from those areas’ and this applies to both donors of non-reproductive tissues and cells and reproductive cells.
ECDC contracted experts from the Institut Pasteur in Paris to systematically review the published evidence on the distribution of HTLV-1 infection prevalence throughout the world and to identify high-prevalence countries and areas. more
Biosafety involves the implementation of containment principles, technologies and practices to prevent unintentional exposure to biological agents. Biosecurity involves the protection, control and accountability of biological materials and informati
...
on related to these materials and dualuse research, to prevent their unauthorized access, loss, theft, misuse, diversion or intentional release.
more
Africa CDC Institute of Pathogen Genomics (IPG) was launched in November 2019 and operates under the Division of Laboratory Systems and Networks.
IPG coordinate the implementation of molecular diagnostics, pathogen genomics and bioinformatics in National Public Health Institutions (NPHIs) and/or Re
...
fe-
-rence Laboratories (NRLs) across Africa.
Africa CDC and APHF are coordinating a continental initiative to maximize the benefits of molecular approaches and pathogen genomics for more effective
outbreak preparedness, prevention, response, and for the control and elimination of endemic diseases in Africa. One of Africa CDC’s flagship initiative is the Africa
Pathogen Genomics Initiative (Africa PGI), a partnership that aims to strengthen laboratory systems and enhance genomic surveillance by equipping the continent’s
public health institutions with the tools, training, and data infrastructure.
About the Project
In 2023, 166 outbreaks and public health events were reported in Africa. This calls for a resilient laboratory systems for timely detection and reporting of current and future outbreaks. This project aims to scale up molecular diagnostic and genomic sequencing-based detection and characterization of outbreaks.
Africa CDC is working with Member States to develop guidance, diagnostic algorithm, training and capacity building to enable outbreak detection, and reporting to inform public health response.
more
Infection prevention and control measures for Ebola virus disease
This document provides guidance on the application of non-pharmaceutical countermeasures to minimise the spread of the 2019 novel coronavirus (2019-nCoV) in the population. Some of the measures proposed refer specifically to certain phases of the epidemic (containment or mitigation phases), and can
...
be adapted depending on the assessed severity/impact of the infection. Other measures are valid for all phases of an epidemic.
The guidance is based on the current knowledge of the 2019-nCoV and evidence available on other viral respiratory pathogens, mainly the Severe Acute Respiratory Syndrome coronavirus (SARS-CoV), the Middle East Respiratory Syndrome-related coronavirus (MERS-CoV) and seasonal or pandemic influenza viruses.
more
Non-pharmaceutical interventions (NPI) are public health measures that aim to prevent and/or control SARS-CoV-2 transmission in the community. As long as there is no effective and safe vaccine to protect those at risk of severe COVID-19, NPI are the
...
most effective public health interventions against COVID-19. These ECDC guidelines detail available options for NPI in various epidemiologic scenarios, assess the evidence for their effectiveness and address implementation issues, including potential barriers and facilitators.
more
This clinical job aid addresses the importance of maternal health and antiretroviral therapy adherence, as well as care and testing for the HIV-exposed infant until the infant’s final HIV diagnosis after the end of breastfeeding.
Prevention Stigma Poster
The Guideline for Disinfection and Sterilization in Healthcare Facilities, 2008, presents evidence-
based recommendations on the preferred methods for cleaning, disinfection and sterilization of patient-
care medical devices and for cleaning and disinfecting the healthcare environment. This docume
...
nt
supercedes the relevant sections contained in the 1985 Centers for Disease Control (CDC) Guideline for
Handwashing and Environmental Control. 1 Because maximum effectiveness from disinfection and
sterilization results from first cleaning and removing organic and inorganic materials, this document also
reviews cleaning methods. The chemical disinfectants discussed for patient-care equipment include
alcohols, glutaraldehyde, formaldehyde, hydrogen peroxide, iodophors, ortho-phthalaldehyde, peracetic
acid, phenolics, quaternary ammonium compounds, and chlorine. The choice of disinfectant,
concentration, and exposure time is based on the risk for infection associated with use of the equipment
and other factors discussed in this guideline. The sterilization methods discussed include steam
sterilization, ethylene oxide (ETO), hydrogen peroxide gas plasma, and liquid peracetic acid. When
properly used, these cleaning, disinfection, and sterilization processes can reduce the risk for infection
associated with use of invasive and noninvasive medical and surgical devices. However, for these
processes to be effective, health-care workers should adhere strictly to the cleaning, disinfection, and
sterilization recommendations in this document and to instructions on product labels.
LAST UPDATE 2019
more
If you’re interested in preventing type 2 diabetes, this guide can help you get started. Congratulations on taking the first step! By reading this, you’re already on your way. Prediabetes puts you on the road to possibly getting type 2 diabetes. Find out now, in less than 1 minute, if you may ha
...
ve prediabetes by taking the Prediabetes Risk Test. If your result shows you’re at high risk for type 2 diabetes, talk to your doctor about getting a simple blood sugar test to confirm it. Then, if you’re diagnosed with prediabetes, consider joining a lifestyle change program offered by the National Diabetes Prevention Program (National DPP). This program is proven to cut the risk for type 2 diabetes in half.
more
Prevention
Crisis and Emergency Risk Communication is an approach to communicating effectively during emergencies. These principles are used by public health professionals and public information officers to provide information that helps individuals, stakeholders, and entire communities make the best possible
...
decisions for themselves and their loved ones. CERC recognizes that during emergencies, we work under impossible time constraints and must accept the imperfect nature of our choices. CERC draws from lessons learned during public health emergencies and research in the fields of public health and emergency risk communication.
The CERC program consists of 1) training, 2) resources, and 3) shared learning.
more
Social distancing is an action taken to minimise contact with other individuals; social distancing measures comprise one category of non-pharmaceutical countermeasures (NPCs)1 aimed at reducing disease transmission and thereby also reducing pressure
...
on health services.
This document builds upon existing ECDC documents, including guidelines for the use of non-pharmaceutical measures to delay and mitigate the impact of 2019-nCoV, a rapid risk assessment: outbreak of novel coronavirus disease – 5th update, a technical report on the use of evidence in decision-making during public health emergencies, and a guidance document on community engagement for public health events caused by communicable disease threats in the EU/EEA.
more
In 2006, the Special Session of African Union Health Ministers adopted the Maputo Plan of Action for implementing the Continental Policy Framework on sexual and reproductive health and rights (SRHR), which expired at the end of 2015. The goal was for all stakeholders and partners to join forces and
...
re-double efforts, so that together, the effective implementation of the Continental Policy framework including universal access to sexual and reproductive health by 2015 in all countries in Africa can be achieved. The Revised Maputo Plan of Action (MPoA) 2016 – 2030 was subsequently endorsed by the African Union Heads of State at the 27th AU Summit in July 2016 in Kigali, Rwanda. The plan reinforces the call for universal access to comprehensive sexual and reproductive health services in Africa and lays foundation to the Sustainable Development Goals, particularly Goal 3 and 5, as well as the African Union Agenda 2063.
more
Sexually Transmitted Diseases Treatment Guidelines, 2015
Centers for Disease Control and Prevention
(2015)
CC
Introduction to the Core Curriculum on Tuberculosis: What the Clinician Should Know
Center for Disease Control and Prevention
(2013)
Sixth Edition
Clinician Outreach and Communication Activity (COCA) Call
April 12, 2016
The purpose of this interim guidance is to provide information and insight to assist public policy and
health system leaders in preparing for and responding to an MCE caused by terrorist use of explosives
(TUE). This document provides practical information to promote comprehensive mass casualty ca
...
re
in the event of a TUE event and focuses on two areas:
1. leadership in preparing for and responding to a TUE event, and
2. effective care of patients in the prehospital and hospital environments during a TUE event.
more
This factsheet describes the work and activities of the Center for Disease Control and Prevention (CDC) in Mozambique as well as its impact in this
...
country.
more
The Pocket Guide to Managing Contraceptive Supplies addresses one of
the most important components of any program that provides family
planning services—the logistics system that manages the delivery,
quality, and storage of contraceptive supplies. These supplies are
essential; without them, f
...
amily planning services cannot be provided.
This guide is for the staff of family planning or health clinics who
manage contraceptive supplies and for the supervisor who oversees
these logistics activities. This booklet is not a complete logistics text;
its purpose is to be a quick reference for logistics formulas and
principles to help you manage your supplies (both contraceptives and
other commodities) correctly and efficiently.
more
Formularies are lists of antibiotics that are suggested for certain healthcare settings. In developing a recommended formulary, countries should consider the needs of patients and facilities where they receive care. For example, clinicians in rural or primary health centers may need wide access to f
...
irst-line antibiotics (e.g., penicillin, ampicillin, TMP-SMX), but last resort antibiotics such as carbapenems or colistin might be limited to tertiary care hospitals. Efforts to create antibiotic formularies may be linked to efforts within countries to create or update essential medicine lists (EML).
more
Preventing Suicide: A Technical Package of Policy, Programs, and Practices
Stone, D.; K. Holland, B. Bartholow, et al.
Centers for Disease Control and Prevention CDC
(2017)
C_CDC
This technical package represents a select group of strategies based on the best available evidence to help communities and states sharpen their focus on prevention activities with the greatest potential to prevent suicide
Veterinarians are leaders and stewards in preserving the effectiveness of antibiotics for animals and people. Working with animal owners and producers, veterinarians can slow antibiotic resistance by implementing disease
...
prevention strategies and improving the use of antibiotics while also guaranteeing high-quality medical care for animal patients.
more
Healthcare-associated infections (HAI) are a significant burden globally, with millions of patients affected each year. These infections affect both high- and limited-resource healthcare settings, but in limited-resource settings, rates are approximately twice as high as high-resource settings (15 o
...
ut of every 100 patients versus 7 out of every 100 patients). Furthermore, rates of infections within certain patient populations are significantly higher in limited-resource settings, including surgical patients, patients in intensive-care units (ICU) and neonatal units. It is well documented that environmental contamination plays a role in the transmission of HAIs in healthcare settings. Therefore, environmental cleaning is a fundamental intervention for infection prevention and control (IPC).It is a multifaceted intervention that involves cleaning and disinfection (when indicated) of the environment alongside other key program elements to support successful implementation (e.g., leadership support, training, monitoring, and feedback mechanisms). To be effective, environmental cleaning activities must be implemented within the framework of the facility IPC program, and not as a standalone intervention. It is also essential that IPC programs advocate for and work with facility administration and government officials to budget, operate and maintain adequate water, sanitation and hygiene (WASH) infrastructure to ensure that environmental cleaning can be performed according to best practices.
more
Recommendations from the American Nurses Association/Centers for Disease Control and Prevention Workgroup on the Role of Registered Nurses in Hospi
...
tal Antibiotic Stewardship Practices
more
Manufacturing Facility Assessment Toolkit
recommended
Tools and resources for occupational safety and health professionals and state and local public health officials assessing manufacturing facilities.
Occupational safety and health professionals and state and local public health officials can use these tools to assess coronavirus
...
disease 2019 (COVID-19) infection prevention and control measures at manufacturing facilities, as well as these facilities’ overall hazard assessment and control plans
more
MMWR Morb Mortal Wkly Rep. ePub: 4 December 2020. DOI: http://dx.doi.org/10.15585/mmwr.mm6949e2
Pwoteje Manje ak Dlo Apre yon Dezas oswa Sitiyasyon Ijans
Rete lwen danje apre yon Siklòn
Leishmaniasis is a parasitic disease that is found in parts of the tropics, subtropics, and southern Europe. Leishmaniasis is caused by infection with Leishmania parasites, which are spread by the bite of infected sand flies. There are several diffe
...
rent forms of leishmaniasis in people. The most common forms are cutaneous leishmaniasis, which causes skin sores, and visceral leishmaniasis, which affects several internal organs (usually spleen, liver, and bone marrow).
more
Website last accessed on 18.03.2023
Education and information about ascariasis, including fact sheets and information on prevention and control, epidemiology, diagnosis and treatment.
Website last accessed on 18.03.2023
Education and information about hookworm including fact sheets and information on prevention and control, epidemiology, diagnosis and treatment.
Website last accessed in 24.03.2023
CDC provides continuing education for professionals involved in rabies prevention and control. While CDC provides some resources directly, others are offered
...
through partnerships and collaborations with other public health entities. This page contains a collection of course notifications, education materials, and continuing education courses related to rabies prevention and control.
more
The Public Health Burden of Secondhand Exposure to Commercial Tobacco Smoke Secondhand smoke, the combination of smoke from burning commercial tobacco* products and the smoke breathed out by a person who is smoking, is deadly.
Epidemiology of Primary Multidrug-Resistant Tuberculosis, Vladimir Region, Russia
J. V. Ershova, G. V. Volchenkov, D. A. Kaminski, et al.
Centers for Disease Control and Prevention
(2015)
C_CDC
Emerging Infectious Diseases; Vol. 21, No. 11, November 2015
In order to maintain daily operations and patient care services, health care facilities need to develop an Emergency Water Supply Plan (EWSP) to prepare for, respond to, and recover from a total or partial interruption of the facilities’ normal water supply. Water supply interruption can be caused
...
by several types of events such as natural disaster, a failure of the community water system, construction damage or even an act of terrorism.
The planning guide provides a four step process for the development of an EWSP:
1. Assemble the appropriate EWSP Team and the necessary background documents for your facility;
2. Understand your water usage by performing a water use audit;
3. Analyze your emergency water supply alternatives; and
4. Develop and exercise your EWSP more
The planning guide provides a four step process for the development of an EWSP:
1. Assemble the appropriate EWSP Team and the necessary background documents for your facility;
2. Understand your water usage by performing a water use audit;
3. Analyze your emergency water supply alternatives; and
4. Develop and exercise your EWSP more
Clinical Presentation and Management for Haiti Cholera Outbreak, 2010
Fason pou Gen Laviktwa sou Kolera
recommended
The document titled "Fason pou Gen Laviktwa sou Kolera" (How to Achieve Victory over Cholera) provides comprehensive guidelines on the clinical presentation and management of cholera, particularly in the context of the 2010 Haiti outbreak. It emphasizes rapid rehydration as a lifesaving measure, det
...
ailing protocols for both oral rehydration solutions (ORS) and intravenous (IV) fluids. The document outlines appropriate antibiotic treatments based on patient categories, underscores the importance of proper sanitation, and offers strategies for effective outbreak control. Additionally, it provides guidance on recognizing severe dehydration and the necessity of immediate medical intervention to reduce mortality associated with cholera.
more
Community Assessment For Public Health Emergency Response (Casper) Toolkit; third edition 3.2
recommended
2nd edition
Pink Book's chapter
The CDC document "How to make oral rehydration solution (ORS)" provides clear, step-by-step instructions for preparing and using ORS to treat dehydration caused by diarrhea. It emphasizes the importance of using clean water, salt, and sugar in precise proportions to create the solution. The document
...
is particularly relevant in emergency settings, such as during cholera outbreaks or in areas with limited medical resources, like Haiti. It highlights the effectiveness of ORS in saving lives by rehydrating individuals suffering from severe diarrhea and encourages its use as a simple, accessible treatment method.
more
Accessed June 2014
Accessed June 2014
Accessed June 2014
Accessed June 2014
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Accessed June 2014
Accessed June 2014
Accessed June 2014
Accessed June 2014
Accessed June 2014
Accessed June 2014
Accessed June 2014
Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations
Bernard M. Branson, S. Michele Owen, Laura G. Wesolowski et
Centers for Disease control and Prevention
(2014)
C_CDC
This document updates recommendations for HIV testing by laboratories in the United States and offers approaches for reporting test results to persons ordering HIV tests and to public health authorities. The recommended algorithm is a sequence of tests used in combination to improve the accuracy of
...
the laboratory diagnosis of HIV based on testing of serum or plasma specimens. The updated recommendations also include tests for HIV antigens and HIV nucleic acid because studies from populations at high risk for HIV demonstrate that antibody testing alone might miss a considerable percentage of HIV infections detectable by virologic tests
more
Listen and download Ebola Radio Health Messages in Local Languages from the website http://www.cdc.gov/vhf/ebola/outbreaks/guinea/radio-spots.html
For use with travelers who may have symptoms consistent with Ebola and were recently in an area affected by an Ebola outbreak, but have no other known exposures
For use with travelers who might have been exposed to patients with Ebola and are sick with symptoms consistent with Ebola infection and require further evaluation
Possible Exposure: Ebola: What you need to do
CDC course for volunteers going to Africa. Please find out mor infos on the CDC website
Morbidity and Mortality Weekly Report Suppl. Vol.63/3
Please download from the webiste: Large File 24,4 MB!
