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Multi-country outbreak of mpox, External situation report #42- 9 November 2024

World Health Organisation (WHO) (2024) C_WHO

This is the 42nd situation report for the multi-country outbreak of mpox, which provides an update on the epidemiological situation of mpox in Africa (including countries in the WHO African Region and some countries in the WHO Eastern Mediterranean Region), with data as of 3 November 2024.

Young People’s Guide to Climate Change and Children’s Health

UN Children's Fund UNICEF (2024) CC

“We must not forget that no matter where we are or how old we are, we can all work for life and take action.” Francisco Vera, 15, UNICEF Child Advocate The Young Climate Activists toolkit was created by advocates of all ages who, like you, are deeply concerned about our planet's future. Havin... more

Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

Antimicrobial Resistance Surveillance Guidance for the African Region

Africa Center for Disease Control and Prevention (2024) CC

Antimicrobials are medicines, including antibiotics, antivirals, antifungals, and antiparasitics, that are used to prevent and treat infections in humans, animals, and plants. Antimicrobial Resistance (AMR) arises when bacteria, viruses, fungi, and parasites no longer respond to these medicines, ren... more

Multiple first-line therapies as part of the response to antimalarial drug resistance

World Health Organization WHO (2024) C_WHO

Effective malaria case management requires quick access to diagnostics and antimalarial treatments to reduce illness and death. Artemisinin-based combination therapy (ACT) has been essential to malaria treatment since 2001, as it combines artemisinin for rapid parasite reduction with a partner drug ... more

Beyond diagnosis and treatment The social protection landscape for people affected by TB in the WHO South-East Asia Region, 2024

World Health Organization WHO (2024) C_WHO

The social protection landscape for people affected by TB in the WHO South-East Asia Region

Regional training package on integrated care for health and development of newborns and children under five at home: participant manual

World Health Organization WHO (2024) C_WHO

Regional training package

Community health workers to improve uptake of maternal healthcare services: A clusterrandomized pragmatic trial in Dar es Salaam, Tanzania

Geldsetzer, P.; Mboggo, E.; Larson, E.; et al. (2019) CC2

PLoS Med 16(3): e1002768. https://doi.org/10.1371/journal.pmed.1002768 Home delivery and late and infrequent attendance at antenatal care (ANC) are responsible for substantial avoidable maternal and pediatric morbidity and mortality in sub-Saharan Africa. This cluster-randomized trial aimed to de... more

Essential and actionable measures for enhancing country preparedness for Viral Haemorrhagic Fever outbreaks in the WHO African Region
recommended

World Health Organization WHO (2024) C_WHO

The target audience of this document (and the associated online companion tool) includes WHO country offices in Member States of the African Region; Member States’ ministries of health and their public health emergency operation centres; relevant external assessment teams; and partners looking... more

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Adolescent HIV Care and Treatment: A Training Curriculum for Health Workers . Module 6 Presentation Manual

ICAP; CDC; University Teaching Hospital, et al. (2011)

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Country Profile on Disability Ethiopia

The World Bank (2002) C1

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Nigeria: National Policy And Strategic Plan of Action On Non-Communicable Diseases (NCDs)

Federal Ministry of Health, Nigeria (2013) C1

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India: Training Module on HIV/Aids (Mainstreaming Cell NACO)

National AIDS Control Organization (NACO), Ministry of Health and Family Welfare, Government of India (2014) C1

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Hiding behind the coalition

Human Rights Watch (2018)

Failure to Credibly Investigate and Provide Redress for Unlawful Attacks in Yemen

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Global action plan on the public health response to dementia 2017-2025

World Health Organization WHO (2017) C_WHO

Areas for action include: increasing prioritisation and awareness of dementia; reducing the risk of dementia; diagnosis, treatment and care; support for dementia carers; strengthening information systems for dementia; and research and innovation.

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Water, Sanitation and Hygiene Guidelines

Mercy Corps USAID (2009) C1

Community Health Worker Assessment and Improvement Matrix (CHW AIM): A Toolkit for Improving CHW Programs and Services

L. Crigler; K. Hill; R. Furth; et al. USAID From the American People (Health Care Improvement Project) (2013) C2

Revided Version September 2013

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COVID-19 in Africa: Protecting Lives and Economies

The Economic Commission for Africa (ECA) (2020) C1

The ECA, says over 300,000 Africans could lose their lives due to COVID-19. This, as the pandemic continues to impact on the Continent’s struggling economies whose growth is expected to slow down from 3.2 percent to 1.8 percent in a best-case scenario, pushing close to 27 million people into extr... more

Bench aids for the diagnosis of intestinal parasites 2nd edition
recommended

World Health Organization WHO (2019) C_WHO

2nd edition

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National Policy and Strategic Plan of Action on Prevention and Control of Non-Communicable Diseases (NCDs) Nigeria

Federal Ministry of Health Nigeria (2013) CC

As part of our commitment to the fight against NCDs, Nigeria was signatory to the political declaration at the UN General Assembly High Level Meeting on NCDs in September 2011. Thus, the purpose of this document is to develop and ensure the implementation of policies and p... more

Essential and actionable measures for enhancing country preparedness for Viral Haemorrhagic Fever outbreaks in the WHO African Region recommended

Bench aids for the diagnosis of intestinal parasites 2nd edition recommended

Essential and actionable measures for enhancing country preparedness for Viral Haemorrhagic Fever outbreaks in the WHO African Region
recommended

Bench aids for the diagnosis of intestinal parasites 2nd edition
recommended