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Waiting for a success story in prevention, control and treatment of Chagas disease in non-endemic countries

Bartoloni, A. Memorias do Instituto Oswaldo Cruz (2022) CC
Chagas disease (CD) is endemic in the Americas, being present in 21 countries, where it affects about 6 million people.(1) With such relevant numbers of people affected and disability adjusted life years lost, CD is a poverty-related and poverty-promoting disease. Although data describe a relevan... more
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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

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This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more
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WHO consolidated guidelines on tuberculosis Module 1: prevention - tuberculosis preventive treatment, second edition

World Health Organisation (WHO) (2024) C_WHO
About one fourth of the world’s population is estimated to have been infected with the tuberculosis (TB) bacilli, and about 5–10% of those infected develop TB disease in their lifetime. The risk for TB disease after infection depends on several factors, the most important being the person’s im... more
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National Review of Community Home Based Care and Access to Treatment Services in Zimbabwe

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World Health Organization (2013)
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Monitoring Guide and Toolkit for Key Population HIV Prevention, Care, and Treatment Programs

FHI 360 (2016) C1
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World Health Organization WHO, et al. (2018) C_WHO
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Recommended package of interventions for HIV, viral hepatis and STI prevention, diagnosis, treatment and care for people who inject drugs: policy brief

World Health Organisation (WHO) (2023) C_WHO
HIV, viral hepatitis and STI epidemics, particularly among people who inject drugs and other key populations, continue to be fuelled by laws and policies criminalizing sex work; drug use or possession; diverse forms of gender expression and sexuality; stigma and discrimination; gender discrimination... more
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Integrating psychosocial interventions and support into HIV services for adolescents and young adults

World Health Organisation (WHO) (2023) C_WHO
Adolescence, defined as the period between 10 and 19 years of age, is a developmental stage during which many psychosocial and mental health challenges emerge. There is a well-established link between mental health and HIV outcomes. Adolescents and young adults living with HIV typically have additio... more
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Report of the Guideline Development Group Meeting on the use of bedaquiline in the treatment of multidrug-resistant tuberculosis

World Health Organization (2017) C_WHO
A review of available evidence (2016). 28-29 June 2016; Geneva, Switzerland The END TB strategy.
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National consolidated guidelines for the prevention of mother-to-child transmission of HIV (PMTCT) and the management of HIV in children, adolescents and adults
recommended

Dept. of Health, Republic of South Africa (2015) C1
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Monitoring HIV, HCV, TB and Harm Reduction in Prisons: A Human Rights-Based Tool to Prevent Ill Treatment

G. Sander Harm Reduction International; European Union (2016) C2
February 2016
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Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with presumptive pulmonary tuberculosis

Zifodaya, J.; et al. Cochrane (2021) C1
Cochrane Database of Systematic Reviews 2021, Issue 2. Art. No.: CD009593. DOI: 10.1002/14651858.CD009593.pub5.
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Prevention of Mother-to-Child Transmission of HIV and Paediatric HIV Care and Treatment Monitoring: From Measuring Process to Impact and Elimination of Mother-to-Child Transmission of HIV

P. Idele; C. Hayashi; T. Porth; et al. AIDS and Behavior; SpringerLink (2017) C2
AIDS Behav (2017) 21:S23–S33 DOI 10.1007/s10461-016-1670-9
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The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies

Maguire, B.; Dahal, P.; Rashan, S.; et al. (2021) CC
PLoS Neglected Tropical diseases August 16, 2021 https://doi.org/10.1371/journal.pntd.0009697 Chagas disease, also known as American trypanosomiasis, is a neglected tropical disease transmitted by triatomine insects, first identified in 1909. Chagas disease affects approximately 6–7 million peop... more
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The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level data plat

Maguire, B.J.; Dahal, P.; Rashan, S. et al. PLOS Neglected Tropical Diseases (2021) CC
PLoS Negl Trop Dis 15(8): e0009697. Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations still exist in our understanding of CD. Harnessing individual participant data (IPD) from studies could support more in-depth analyses t... more