Despite the significant role of vector control in national leishmaniasis control programmes, the programmatic community perceives vector control as the weakest component of leishmaniasis control strategies in terms of resources, scientific evidence of the usefulness of interventions and capacity for... quality-assured implementation. Therefore, the main objective of this manual is to provide practical tools, techniques and procedures to strengthen sand fly control and surveillance in order to improve implementation of leishmaniasis control programmes. The manual provides a rationale for programme managers in different geographical regions on the types of vector control interventions to be used in different epidemiological and environmental settings and also how to measure their impact.
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Front Chem. 2021; 9: 622286.
Published online 2021 Mar 12. doi: 10.3389/fchem.2021.622286
En la era del cambio digital, democrático, social y político, la comunicación se ha convertido en un medio esencial para expresar ideas y desarrollar iniciativas revolucionarias, capaces de crear comunidades más fuertes, mejor informadas y más comprometidas que nunca. El surgimiento del periodi...smo ético se ha vuelto fundamental para las salas de prensa y es el pilar de las noticias periodísticas que favorecen el desarrollo de la sociedad. Al comenzar estos cambios, la cuestión del género se vuelve inseparable del tema del progreso y del periodismo ético.
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El informe de este año presenta una actualización de la situación de la seguridad alimentaria y la nutrición en América Latina y el Caribe, incluyendo también estimaciones actualizadas sobre el costo y la asequibilidad de una dieta saludable (Parte 1). Además, el informe examina el complejo e...scenario económico y social de la región y su impacto en el costo de las dietas saludables, para luego entregar un examen del costo y la asequibilidad de una dieta saludable a nivel subregional y nacional, incluyendo las asociaciones entre la inasequibilidad de una dieta saludable y los indicadores socioeconómicos y nutricionales (Parte 2). Además, esta edición del Panorama regional presenta un análisis de algunas políticas alimentarias y agrícolas que se están implementando en la región y que tienen el potencial de apoyar el acceso a dietas saludables, así como los factores y dinámicas a través de los cuales éstas actúan.
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This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita...ls in the Democratic Republic of the Congo between August 2005 and September 2009 to support the registration of pafuramidine for treatment of first stage HAT in collaboration with the United States Food and Drug Administration. Patients were treated with either 100 mg of pafuramidine orally twice a day for 10 days or 4 mg/kg pentamidine intramuscularly once daily for 7 days to assess the efficacy and safety of pafuramidine versus pentamidine. Pregnant and lactating women as well as adolescents were included.
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El maltrato infantil incluye la perpetración de violencia física, sexual y psicológica o emocional, y el descuido de bebés, niños, niñas y adolescentes de 0 a 17 años por parte de progenitores, cuidadores y otras figuras de autoridad, con mayor frecuencia en el hogar, pero también en entorno...s como escuelas y orfanatos. Es un problema importante de salud pública y
una violación de los derechos humanos fundamentales, incluido el derecho a la vida, el derecho a la protección contra todas las formas de violencia y el derecho al goce del grado más alto posible de salud. El maltrato infantil puede tener consecuencias negativas graves y, a menudo, de por vida para la salud mental y física, la salud sexual y reproductiva, el desempeño
académico y la vida social.
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Este manual se ha elaborado en el marco de la Iniciativa Global de la Organización Mundial de la Salud (OMS) para el Cáncer Infantil, CureAll Americas, con el propósito de mejorar la situación de los niños, niñas y adolescentes con cáncer en todo el mundo, para que puedan tener las mejores po...sibilidades de sobrevida, disfrutar de una vida plena y, sobre todo, alcanzar la mejor calidad de vida posible y morir sin sufrimiento. Está dirigido a los profesionales de la salud que se dedican al tratamiento de pacientes oncológicos pediátricos y que, directa o indirectamente, deben enfrentarse con las complicaciones que pueda causar el tratamiento a todos los niveles. Su contenido puede contribuir a la realización de un diagnóstico más certero de las alteraciones de la cavidad oral, así como al desarrollo de estrategias para la prevención y el tratamiento de estas manifestaciones. No se establecen orientaciones directas para responsables parentales ni cuidadores, pero sí se presenta información que sirve como guía para el cuidado bucal, de acuerdo con la estructura y la composición de los equipos de los distintos centros de tratamiento contra el cáncer.
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Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological settings and affects vulnerable populations, such as rural subsistence farmers and urban slum dwellers. Although leptospirosis is a life-threatening disease and recognized as an important cause of pulmonary haemorrhage syndrom...e, the lack of global estimates for morbidity and mortality has contributed to its neglected disease status
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Snakebite envenoming affects millions of people worldwide annually and is a significant source of mortality. Preventing and treating the problem is complex and requires collaboration among the fields of public health, medicine, ecology, and laboratory science. After being removed from the category A... neglected tropical disease (NTD) list in 2013, snakebite envenoming was reinstated in 2017 in response to antivenom shortages and advocacy from researchers and international NGOs. In 2019, the World Health Organization (WHO) set a target to halve the number of deaths and cases of snakebite envenoming by 2030.
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The WHO continuously reviews available data on SARS-CoV-2 variants of concern. For this version, the global epidemiological
situation of the COVID-19 pandemic as of 21 January 2022 – at a time when the Omicron VOC had been identified in 171
countries across all six WHO Regions and was rapidly re...placing Delta worldwide – was considered Omicron has a substantial growth advantage, higher secondary attack rates and a higher observed reproduction number than Delta.
There is now significant evidence that immune evasion contributes to the rapid spread of Omicron. Other factors may be a shorter
serial interval (by about 0.8 to 1.2 days compared to Delta) and potential increased intrinsic transmission fitness . There is
growing evidence that with Omicron, there is lower vaccine effectiveness (VE) against infection and symptomatic disease soon after vaccination compared to Delta. There is also evidence of accelerated waning of VE over time of the primary series against infection and symptomatic disease for the studied vaccines. Further studies are required to better understand the drivers of transmission and declining incidence in various settings. These factors include the intrinsic transmission fitness properties of the virus, degree of immune evasion, vaccination coverage and level of vaccine-derived and post-infection immunity, levels of social mixing and degree of application of public health and social measures (PHSM).
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Rabies is a devastating and societally important zoonotic disease, which is transmitted principally to humans through the bite of infected dogs. This acute, progressive viral encephalitis has the highest case fatality of any infectious disease and kills tens of thousands of people annually, with chi...ldren and impoverished communities being affected disproportionately.
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Rabies has an enormous impact on both agriculture and conservation biology, but its greatest burden is undeniably on public health. As such, routine methods for rapid risk assessment after human exposures to rabies as well as applications for laboratory-based surveillance, production of biologicals ...and management of this infectious disease are critical. Given its mandate to improve human health and control disease among its Member States, WHO has led the production of this fifth edition of Laboratory techniques in rabies.
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A medida que el tratamiento antirretrovírico con dolutegravir se extiende a más personas que viven con el VIH en el
mundo, adquiere más importancia estimar la frecuencia con que surge la farmacorresistencia adquirida a este
antirretrovírico en las poblaciones tratadas con esquemas que lo conti...enen. Si bien no se ha detectado resistencia
al dolutegravir en los ensayos clínicos con poblaciones no tratadas antes con antirretrovíricos en las que se ha
detectado una viremia persistente pese al tratamiento, los datos indican que puede surgir en quienes toman esquemas
con dolutegravir. La OMS recomienda a los países que estén ampliando el tratamiento con dolutegravir que acompañen
su despliegue con la vigilancia sistemática de la farmacorresistencia.
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Mothers, newborns, young children and adolescents are losing 20 percent of their health and social services due to the COVID-19 pandemic says a Panel of senior global health experts.
A aplicação da tecnologia digital de saúde está crescendo rapidamente na África, com o
objetivo de melhorar a prestação de serviços de saúde e alcançar de forma mais eficaz
comunidades remotas e carentes. A falta de diretrizes e padrões habilitadores em todo o
continente, por outro ...lado, dificulta o compartilhamento de dados de forma significativa em
todo o continente. Considerando isso, os Centros Africanos de Controle e Prevenção de
Doenças (CDC África) estabeleceram uma força-tarefa de 24 membros para fornecer
experiência e orientação no desenvolvimento de diretrizes e padrões da AU HIE. Os membros
da força-tarefa eram especialistas no assunto que trabalhavam na África e
internacionalmente na coleta, análise e troca de informações de saúde. Alguns desses
especialistas estiveram envolvidos em consultas anteriores sobre a definição da estratégia de
sistemas de informação de saúde do CDC África. Um presidente, copresidente e secretário
foram eleitos para envolver os membros da força-tarefa em diferentes grupos de trabalho
técnicos.
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El objetivo general del marco es apoyar a la OMS y a los Estados Miembros en lo relativo a la participación significativa de las personas con enfermedades no transmisibles y afecciones de salud mental y neurológicas con vistas a la creación conjunta y la mejora de políticas, programas y servicio...s que les afectan. Este marco contribuirá a avanzar en la comprensión, el conocimiento y las medidas adoptadas sobre la participación significativa y los enfoques participativos conexos a partir de una base empírica en evolución. En él se ofrece orientación práctica y medidas para pasar de la intención a la acción y hacer realidad la participación significativa. El objetivo del marco es orientar a quienes trabajan en la OMS y en los Estados Miembros para hacer realidad la participación significativa de las personas con experiencia vivida. La OMS promoverá, brindará asistencia técnica y pondrá en marcha el marco en sus tres niveles (Sede, oficinas regionales y oficinas en los países) y apoyará a los Estados Miembros en la aplicación a nivel nacional mediante los procesos y procedimientos establecidos.
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At its 48th session of Codex Committee on Food Hygiene (CCFH), the Committee noted the importance of water quality and safety in food production and processing. CCFH requested the Food and Agriculture Organization of the United Nations
(FAO) and the World Health Organization (WHO) to provide guidan...ce for those scenarios where the use of “clean water” (i.e. water that does not compromise the safety of the food in the context of its use) was indicated in Codex texts and on
where it is appropriate to use “clean water”. In particular, guidance was sought for the use of irrigation water and “clean” seawater and on the safe reuse of processing water.
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Global growth is projected to slow significantly amid high inflation, tight monetary policy, and more restrictive credit conditions. The possibility of more widespread bank turmoil and tighter monetary policy could result in even weaker global growth and lead to financial dislocations in the most vu...lnerable emerging market and developing economies (EMDEs). Comprehensive policy action is needed to foster macroeconomic and financial stability. Among many EMDEs, and especially in low-income countries, bolstering fiscal sustainability will require generating higher revenues, making spending more efficient, and improving debt management practices. Continued international cooperation is also necessary to tackle climate change, support populations affected by crises and hunger, and provide debt relief where needed.
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The Infection prevention and control in the context of coronavirus disease 2019 (COVID-19): a living guideline consolidates technical guidance developed and published during the COVID-19 pandemic into evidence-informed recommendations for infection prevention and control (IPC). This living guideline... is available both online and PDF.
**This version of the living guideline (version 5.0) **includes the following seven revised statements for the prevention, identification and management of SARS-CoV-2 infections among health and care workers:
a good practice statement on national and subnational testing strategies;
a good practice statement on passive syndromic surveillance of health and care workers;
a good practice statement on prioritizing health and care workers for SARS-CoV-2 testing;
a good practice statement on protocols for reporting and managing health and care worker exposures;
a good practice statement to limit in-person work of health and care workers with active SARS-CoV-2 infections;
a statement on high-risk exposures and quarantine; and,
a conditional recommendation on the duration of isolation for health and care workers.
Understanding the updated section
Prevention of infections in the health care setting includes a multi-pronged and multi-factorial approach that includes IPC and occupational health and safety measures and adherence to Public Health and Social Measures in the community by the health workforce. The underlying infection prevention and control strategy of this section is the notion that early identification of symptomatic cases, testing and quarantining/isolating health and care workers decreases the risk of nosocomial infection to patients and to other health and care workers.
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Access to safe blood and blood products is recognized as one of the key requirements for delivery of modern health care in the journey towards health for all. The foundation of safe and sustainable blood supplies depends on the collection of blood from voluntary non-remunerated and low-risk donors. ...Data from the WHO Global Database for Blood Safety (GDBS) brings out several inadequacies related to the supply and safety of blood and blood products. These inadequacies include a number of variations in safe blood practices across the world, including the quantity of blood donated (voluntary and replacement types), quality and adequate testing of the donated blood (immunohaematology [IH] and transfusion-transmitted infections [TTIs]), rational use of blood and blood components such as appropriate patient blood management protocols. These variations are very high in countries of the South-East Asian Region and most of them are either low- or middle-income countries (LMICs).
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