Background
Chronic congestive heart failure is a common condition that, if untreated, markedly impairs the quality of life and is associated with a high risk of recurrent hospitalization and death.
Methods
This review is based on articles retrieved by a selective search in PubMed, as well as on r...elevant guidelines.
Results
Evidence-based treatment options are available only for congestive heart failure with a low ejection fraction. Pharmacotherapy is based on neurohumoral inhibition of the renin-angiotensin-aldosterone system and the adrenergic system. The prognosis of patients with this condition has been further improved recently through the introduction of combined angiotensin receptor antagonists and neprilysin inhibitors. Modern implantable devices are a further component of treatment. Implantable defibrillators and special pacemakers for cardiac resynchronization are well established; the utility of alternative devices (baroreflex modulation or cardiac contractility modulation) needs to be investigated in further studies. It was recently shown that the catheter-based treatment of secondary mitral regurgitation with a MitraClip improves the outcome of selected patients.
Conclusion
The treatment of chronic systolic heart failure as recommended in the relevant guidelines, with drugs and implanted devices if indicated, can significantly improve the clinical outcome.
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Disease epidemiology has a deeper relationship with the dynamic nature of culture. Health behaviors in general are largely shaped by the cultural norms and customs in a society. A mere identification of a behavior could be only a layer on the outer sphere of a particular disease epidemiology and the... interventional efforts to counteract such behaviors through for example public health measures could be futile and volatile, unless the deeper cultural factors are addressed.
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This report on global leishmaniasis surveillance follows those published in 2016–2023.2–6 Six indicators of leishmaniasis are publicly available from the Global Health Observatory (GHO).7 In addition to the GHO, country profiles with up to 30 indicators are published, with detailed data received... from 45 Member States.
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Participatory Learning and Action Planning; A Facilitator's Guide
n Autumn 2013, HHI Executive Director, Vincenzo Bollettino, traveled to the Philippines to participate in an assessment of civil-military engagement in the humanitarian response to Typhoon Haiyan. The report was sponsored by the Center for Excellence in Disaster Management and Humanitarian Assistanc...e.
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Une mission d’appui d’experts diligentés par l’OMS et l’USAID s’est rendue du 17 au 24 novembre au Burkina Faso pour aider le pays dans la mise en place de son plan de prevention et de riposte à une éventuelle épidémie de maladie à virus Ebola. L’équipe a travaillé avec les acteu...rs du niveau national et les partenaires techniques et financiers du pays
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J Hepatol (2017), http://dx.doi.org/10.1016/j.jhep.2017.03.021
Diagnóstico exploratorio sobre el tráfico y/o trata de personas con fines de explotación sexual