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A pocket guide to antibiotic prescribing for adults in South Africa 2015
Wasserman, S.; T. Boyles, M. Mendelson
SOUTH AFRICAN ANTIBIOTIC STEWARDSHIP PROGRAMME (SAASP)
(2015)
C2
The international community sits at the tipping pointof a post-‐antibiotic era, where common bacterial infections are no longer treatable with the antibiotic armamentarium that exists. In South Africa, t
...
he identification of the first case of pan-‐resistant Klebsiella pneumoniae(Brink et al, J Clin Microbiol. 2013;51(1):369-‐72) marks a watershed moment and highlights ourtip of the antibiotic resistance ‘iceberg’ in this country. Multi-‐drug resistant (MDR)-‐bacterial infections, predominantly in Gram-‐negative bacteria such as Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosaand Acinetobacter baumanniiare now commonplace in South African hospitals. Whilst a number of expensive new antibiotics for Gram-‐positive bacterial infections have been manufactured recently (some of which are licenced for usein South Africa), no new antibiotics active against Gram-‐negative infections are expected in the next 10-‐15years. Hence what we have now, needs conserving
more
Временные рекомендации
13 марта 2020 г.
Настоящий документ является вторым изданием руководства (версия 1.2), которое первоначально представляло собой адаптированн
...
ый вариант Руководства по клиническому ведению тяжелой острой респираторной инфекции при подозрении на инфекцию MERS-CoV (ВОЗ, 2019 г.).
more
The infectious disease burden in India is among the highest in the world. A large amount of antibiot-ics are consumed in fighting infections, some of them saving lives, but every use adding to antibiotic resistance in bacteria. Antibiotic use is increasing steadily (table 1), particularly
...
certain antibiotic classes (beta-lactam antibacterials), most notably in the more prosperous states. Resistance follows in lock-step.
more
The escalating antimicrobial resistance (AMR) pandemic is a global public health threat with extensive health, economic and societal implications. Resistance emerges because of selection pressure from rational and indiscriminate antimicrobial use in human health as well as in the veterinary, agricul
...
ture and environmental sectors. Infections caused by resistant bacteria result in longer duration of illness, higher mortality rates and increased costs associated with alternative treatment. AMR further constrains procedures that rely on antimicrobial prophylaxis, and AMR is recognized as a threat to theworld economy.
Journal of Public Health | Vol. 39, No. 1, pp. 8–13 | doi:10.1093/pubmed/fdw015 | Advance Access Publication March 3 2016
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El abuso y el uso indebido de los antibióticos en animales y humanos están contribuyendo al aumento de la resistencia a estos fármacos. Algunos tipos de bacterias causantes de infecciones humanas graves ya son resistentes a la mayoría o a la totalidad de los tratamientos
...
disponibles, y hay muy pocas alternativas prometedoras en fase de investigació
more
A guide for practical implementation in adult and pediatric emergency department and urgent care settings
The primary focus of the plan continues to be prevention, preparedness and treatment of the the Novel Coronavirus (COVID-19) outbreak. Central to the plan are the following overall objectives:
To prevent further transmission of COVID-19 in the oPt;
To provide adequate care for patients aff
...
ected by COVID-19 and to support their families and close contacts; and
To mitigate the worst effects of the pandemic.
more
The purpose of this plan is to:
Present the GoP’s strategy and actions;
Propose an aid coordination approach;
Identify the critical support needs, including for: public health response to COVID-19; budget support to maintain government services; and diplomatic engagement with region
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al partners; and
Describe our expectations of the longer-term economic impact of COVID-19 and required economic recovery actions.
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Pakistan Global Antibiotic Resistance Partnership (GARP) was formed in the wake of international and national efforts for AMR curtailment. A group of experts from microbiology, infectious diseases and veterinary medicine formed a core group at the organizational meet
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ing of GARP in Kathmandu, Nepal in July 2016. In the meeting, this core group was expanded to include other members from different sectors with the selection of the Chair and co-chairs. These were asked to serve on a voluntary basis, in their own individual capacities, with no personal gains, or gains to the institutions to which they are affiliated. The first phase of GARP took place from 2009 to 2011 and involved four countries: India, Kenya, South Africa and Vietnam. Phase one culminated in the 1st Global Forum on Bacterial Infections, held in October 2011 in New Delhi, India. In 2012, phase two of GARP was initiated with the addition of working groups in Mozambique, Tanzania, Nepal and Uganda. Phase three has added Bangladesh, Lao PDR, Nigeria, Pakistan and Zimbabwe to the network to date.
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Haematologica has published European guidelines for empirical and targeted antibacterial therapy forfebrile neutropenic patients in the era of emerging resistance (ECIL-4). Indeed, collateral damage by broad-spectrum antibiotic therapy includes selection of multidrugresistant pathogens, and incr
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eased predisposition to infec-tion by fungi and Clostridium difficile. Antibiotic resistance has become a major public health concern, with fears expressed that we will soon run out of antibiotics.
Haematologica December 2013 98: 1821-1825; doi:10.3324/haematol.2013.091769
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Guidance Note: Protection of Children during Infectious Disease Outbreaks
Arii M., F. Baele, J. Bedford et al.
The Alliance for children protection in humanitarian action
(2020)
C2
Accessed on 31.03.2020
This Guidance Note aims to provide humanitarian child protection practitioners, particularly child protection advisors and program managers, with guidance on how to engage in responses to infectious disease outbreaks to ensure children’s protection needs are taken into ac
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count in preparedness for, and during responses to, the outbreaks. The Guidance Note draws upon lessons learned during infectious disease outbreaks globally in a variety of contexts.
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Antimicrobial resistant (AMR) organisms are increasing globally, threatening to render existing treatments ineffective against many infectious diseases. In Africa, AMR has already been documented to be a problem for HIV and the pathogens that cause malaria, tuberculosis, typhoid, cholera, meningitis
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, gonorrhea, and dysentery. Recognizing the urgent need for action, the World Health Assembly adopted the Global Action Plan on Antimicrobial Resistance in May 2015. In accordance with the Global Action Plan and to meet needs specific to Africa, Africa CDC will establish the Anti-Microbial Resistance Surveillance Network (AMRSNET). AMRSNET is a network of public health institutions and leaders from human and animal health sectors who will collaborate to measure, prevent, and mitigate harms from AMR organisms.
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Jin et al. Military Medical Research (2020) 7:4 https://doi.org/10.1186/s40779-020-0233-6
Position Article und Guideline
Interim Guidance 18th March 2020
Myanmar, as a country going through rapid socio-political transition and institutional development also suffers with a high burden of infectious disease. An ongoing challenge has been to effectively reach its 51 million population, most of whom battle tuberculosis, acute respiratory infections, diar
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rhoea and malaria including amongst under-five children.
Limited research data on the occurrence of resistant organisms in the nation have, makes it hard to estimate the exact antimicrobial resistance (AMR) scenario. Limited peer reviewed evidence indicates significant divergence from the average resistance trends in APAC region. Nevertheless, several key steps by Government of Myanmar have been instrumental in paving the way for the country to join other nations in the South East Asia Region to speed up its plan on addressing the AMR crisis. Combating antimicrobial resistance would, however, require highest political commitment, multi-sectoral coordination, sustained investment and technical assistance.
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Η ανακάλυψη πριν από 80 περίπου χρόνια ότι ουσίες που παράγονται από μύκητες ή βακτήρια μπορούν να χρησιμοποιηθούν θεραπευτικά για την ίαση διαφόρων λοιμώξεων, έφε
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ε επανάσταση στα τότε ιατρικά δεδομένα. Οι λοιμώδεις νόσοι αποτελούσαν τότε την πρώτη αιτία θανάτου για κάθε ηλικιακή ομάδα. Το γεγονός αυτό ανατράπηκε με την έναρξη της χρήσης των ουσιών αυτών, που ονομάστηκαν αντιβιοτικά λόγω της ιδιότητας τους να καταστρέφουν τα μικρόβια. Έκτοτε εκατομμύρια ζωές έχουν σωθεί με τη χορήγηση αντιβιοτικών για την αντιμετώπιση σοβαρών λοιμώξεων. Σήμερα, οκτώ δεκαετίες μετά, οι πολύτιμες αυτές για τον άνθρωπο ουσίες χάνουν με συνεχώς επιταχυνόμενο ρυθμό την αποτελεσματικότητά τους λόγω επίτασης του φαινομένου της Μικροβιακής Αντοχής στα αντιβιοτικά.
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Coronavirus disease 2019 (COVID-19) is an acute infectious respiratory disease caused by a newly discovered coronavirus (SARS-CoV-2).
Most people infected with the COVID-19 virus experience mild to moderate respiratory illness and recover without requiring special treatment, the disease presentati
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on is more likely to be severe in older people, and those with underlying medical problems like cardiovascular disease, diabetes, chronic respiratory disease, etc.
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At this time, information about COVID-19 is rapidly evolving as new details are confirmed and new questions emerge. In the
event of an outbreak in your community, as a parent/caregiver, your first concern is about how to protect and take care of
your children and family. Knowing important informat
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ion about the outbreak and learning how to be prepared can reduce your
stress and help calm likely anxieties. This resource will help you think about how an infectious disease outbreak might affect
your family—both physically and emotionally—and what you can do to help your family cope.
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Vaccines are powerful weapons in the fight against pandemic viruses as shown by responses to both the 2009 H1N1 influenza and the COVID-19 pandemics. However, planning for accessing, allocating and deploying vaccines in a pandemic situation is a complex endeavour, beset with multiple challenges at a
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ll levels – local, regional and global. The World Health Organization (WHO) and its partners have prepared this revised guidance document to assist countries update their national deployment and vaccination plans (NDVPs) by leveraging global learnings from past pandemic responses, including the recent COVID-19 vaccination effort. The development and testing of a NDVP would not only advance pandemic preparedness efforts but would also have benefits in terms of increasing national capabilities to manage other health emergencies which require emergency vaccination campaigns.
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