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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

Tool to assess impact of human resources for health investments on HIV, TB and malaria services and health outcomes

World Health Organization WHO (2022) C_WHO

The WHO Global strategy on human resources for health: workforce 2030 encourages development partners and global health initiatives to leverage their support to health systems in countries to sustainably strengthen the health workforce. To assess th... more

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Measles kit 2021 Rev.1

World Health Organization WHO (2021) C_WHO

7 June 2022. To treat complications associated with measles: severe complications with module 1 (50 cases) and mild complications with module 8 (20 cases). The new measles kit 2021 is designed to prepare for and support the treatment of non-severe ... more

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A global inventory of small floating plastic debris

van Sebille, E.; C. Wilcox, L. Lebreton et al. IOP Science (2015) CC

Environmental Research Letters Microplastic debris floating at the ocean surface can harm marine life. Understanding the severity of this harm requires knowledge of plastic abundance and distributions. Dozens of expeditions measuring microplastics... more

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The sociodemographic impacts of the COVID-19 pandemic in Latin America and the Caribbean

United Nations ECLAC (2022) C1

Latin America and the Caribbean is characterized by a matrix of social inequality whose axes —such as socioeconomic stratum, gender, stage in the life cycle, ethnicity and race, territory, disability, and immigration status— create multiple, o... more

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WHO policy brief: Clinical management of COVID-19, 14 September 2022

World Health Organization WHO (2022) C_WHO

The World Health Organization (WHO) recognizes the challenges countries face for maintaining their COVID-19 response while addressing competing public health challenges, conflicts, climate change and economic crises. WHO continues to support countri... more

Core competencies in disaster nursing: Competencies for nurses involved in emergency medical teams (Level 3)

International Council of nurses (2022) C1

Over the last decade, there have been numerous disasters and major emergencies that have profoundly impacted the lives of millions of people worldwide. To support these crises, national and international emergency medical teams (EMTs) are often depl... more

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Training and deployment of Key Informants (KIs) for case finding for children with severe visual impairment and blindness and Improving the follow up of children after cataract and other surgeries

Kilimanjaro Centre for Community Ophthalmology KCCO (2022) CC

The WHO estimates that 19 million children aged 15 years or younger are visually impaired. Of these, 1.4 million are irreversibly blind and need visual rehabilitation interventions for full psychological and personal development. The remainder have visual problems that could be prevented or treated.... more

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Elimination of human African trypanosomiasis as public health problem

World Health Organization WHO Team Control of Neglected Tropical Diseases (2022) C_WHO

More countries eliminate human African trypanosomiasis as a public health problem: Benin and Uganda (gambiense form) and Rwanda (rhodesiense form) Human African trypanosomiasis (HAT), or sleeping sickness, transmitted by tsetse flies in sub-Saharan Africa, is a ...-threatening disease that afflicts poor rural populations. It is caused by trypanosome parasites of 2 subspecies: Trypanosoma brucei gambiense in West and Central Africa, and T. b. rhodesiense in East Africa. HAT transmission can be reduced and interrupted by deploying and maintaining capacities for testing people at risk in order to detect and treat cases, and by controlling tsetse populations that are in contact with humans. more

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Regional variation in the allocation of development assistance for health

Hanlon et al. Pubmed (2014) CC

The Global Burden of Disease (GBD) 2010 Study has published disability-adjusted life year (DALY) data at both regional and country levels from 1990 to 2010. Concurrently, the Institute for Health Metrics and Evaluation (IHME) has published estimat... more

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A guide to tailoring health programmes: Using behavioural and cultural insights to tailor health policies, services and communications to the needs and circumstances of people and communities

World Health Organization WHO (2023) CC

WHO/Europe has launched a new guide, providing support to countries on how to apply behavioural and cultural insights (BCI) for health. It presents a simple step-wise approach, complemented by a rich collection of detailed considerations, tools and ... more

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UN Women Humanitarian Strategy (2022–2025) In Brief

UN Women (2023) CC

This publication provides an overview of UN Women’s commitments to the humanitarian community guided by the “UN Women strategic plan 2022–2025”. It highlights areas where UN Women has a unique advantage in advancing gender equality and the empowerment of women and girls across the humanitari... more

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8 Steps to Prevent Heart Disease and Stroke - Infographic

American Heart Association (2019) CC

These key factors can help you live a longer, healthier life and reduce your risk of heart disease and stroke. They’re part of an overall healthy lifestyle and prevention approach you can build with your health care team (doctors, nurses, pharmaci... more

MEPs Mobilising for Diabetes Blueprint for Action on Diabetes in the European Union by 2030

MEPs Mobilising for Diabetes (2021) CC2

Since the discovery of insulin nearly 100 years ago, advances in diabetes treatments and therapies have transformed the lives of people with diabetes (PwD), notably reducing the daily burden of its management. Newer technologies, including those driven by artificial intelligence, have the potentia... more

Rehabilitation Task Force Technical Note: Amputations and Prosthetics in Gaza

Health Cluster; World Health Organization WHO (2024) CC

The war in Gaza has resulted in thousands of amputations, including early estimates of over 1000 children, all of whom have immediate and life-long needs. Surgical amputations performed under extremely difficult conditions are likely to be sub-optim... more

Multi-Sector Nutrition Education and Communication Strategy (NECS) II 2021-2025

Government of Malawi; Department of Nutrition; HIV and AIDS Ministry of Health (2021) CC2

The Department of Nutrition, HIV and AIDS (DNHA) in Ministry of Health and Population is grateful to all stakeholders who contributed to the development of the Nutrition Education Communication Strategy II. The DNHA acknowledges the financial and technical ... from the World Bank and USAID through the Nutrition, HIV and AIDS project and Food and Nutrition Technical Assistance Project (FANTA III)/FHI 360, respectively. The participation of several partners including Irish Aid, the European Union (EU), Gesellschaft für Internationale Zusammenarbeit (GIZ), United Nations Children’s Fund (UNICEF), World Food Programme (WFP), World Health Organisation (WHO), Food and Agriculture Organisation (FAO), Civil Society Organisation Nutrition Alliance (CSONA), Concern Worldwide and the Clinton Health Access Initiative(CHAI). more

Trauma induced disorders and Post-Traumatic Stress Disorder (PTSD)

Ethno-Medizinisches Zentrum e. V. (2015) C1

This guide aims to inform about these illnesses - so-called ‘trauma-induced disorders’ - in general and ‘post-traumatic stress disorder’ (PTSD) in particular. It is also designed to offer support in finding treatment and counselling options.

Guidance on global monitoring for diabetes prevention and control: Framework, indicators and application

World Health Organization WHO (2024) C_WHO

The Guidance on global monitoring for diabetes prevention and control by WHO provides a comprehensive framework to support countries in tracking and managing diabetes prevention, care, and outcomes. This document outlines indicators across 4 domains... more

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Global action plan on the public health response to dementia 2017-2025

World Health Organization WHO (2017) C_WHO

Areas for action include: increasing prioritisation and awareness of dementia; reducing the risk of dementia; diagnosis, treatment and care; support for dementia carers; strengthening information systems for dementia; and research and innovation.

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Planning Guidance for Response to a Nuclear Detonation

Interagency Policy Coordination Subcommitee for Preparedness & Response to Radiological and Nuclear Threats (2010)

The purpose of this guidance is to provide emergency planners with nuclear detonationspecific response recommendations to maximize the preservation of life in the event of an urban nuclear detonation. This guidance addresses the unique effects and... more