L’utilisation excessive ou inadaptée des antibiotiques chez l’homme et chez l’animal contribue à amplifier la menace provenant de la résistance à ces produits. Certains types de bactéries susceptibles de provoquer des infections graves chez les humains sont déjà devenus ... résistants à la plupart des traitements disponibles et très peu d’options prometteuses sont actuellement en cours de développement pour prendre le relais
more
En mai 2015, en adoptant le Plan d’action mondial pour combattre la résistance aux antimicrobiens (« Plan d’action mondial »), la Soixante-Huitième Assemblée mondiale de la Santé a reconnu l’importance de cette résistance en tant que problème majeur de santé publi...que. Le Plan propose des interventions pour lutter contre cette résistance, dont la réduction des usages inutiles d’antimicrobiens chez l’homme et chez l’animal. Il souligne aussi la nécessité d’une approche intersectorielle, « Un monde, une santé », pour endiguer cette résistance, impliquant des efforts de la part d’acteurs de nombreuses disciplines, dont les médecines humaine et vétérinaire
more
Using antimicrobials responsibly is an essential component ofefforts to contain antimicrobial resistance (AMR), and to ensurethat patients receive appropriate treatment. The WHO global action plan on AMR emphasizes the importance of training healthcare professionals in antimicrobial prescribing and ...stew-ardship (AMPS). There are several challenges, however, such asthe wide range of healthcare professionals involved in the pre-scribing process, and the heterogeneity of prescribing rights and practices of different professional groups within and between countries. One way to address these challenges is through developing competencies, which define the minimum standards that all antimicrobial prescribers should reach.
Clinical Microbiology and Infection 25 (2019) 13e19
more
Antimicrobial stewardship (AMS) describes a coherent set of actions that ensure optimal use of antimicrobials to improve patient outcomes, while limiting the risk of adverse events (including antimicrobial resistance (AMR)). Introduction of AMS programmes in hospitals is part of most national action... plans to mitigate AMR, yet the optimal components and actions of such a programme remain undetermined.
more
Antibiotic stewardship refers to coordinated efforts and activities that seek to measure and improve use of antibiotics. Implementation of ASPs has demonstrated positive public health and clinical impacts including reducing costs, lengths of hospital stays, and the burden of antibiotic resistance wh...ile maintaining or improving patient outcomes. The U.S. Centers for Disease Control and Prevention (CDC) released the Core Elements of Hospital Antibiotic Stewardship Programs in 2014, which outlines essential components for ASPs in hospitals and provides practical guidance for implementing a robust ASPin an acute care facility. Variations to the Core Elements have been developed to deal with the particular challenges in small, rural or critical access hospitals in the United States and in outpatient facilities and nursing homes.
more
This small scale project aimed to optimize antibiotic prescriptions for Urinary Tract Infections (UTI) at Okhaldhunga Community Hospital in Nepal. A review of 18 months data from urine cultures taken in the hospital was completed in 2017. Presentations about antibiotic resistance, the local bacteria...l culture results and possible ways of changing prescription pattern were given for doctors, lab staff and community medical assistants (CMA). 16 months later the prescription rate of antibiotics frequently used for UTIs was followed up, with a 57% reduction of ciprofloxacin consumption!
more
App - Learn how to handle antibiotics with care & help us stop antibiotic resistance
Improve your knowledge of the spread of antimicrobial resistance in Africa and how to reduce it - Online Course
This course will offer a practical approach to prescribing antibiotic therapy and development of antimicrobial stewardship across all specialties and settings. Antibiotics are among the most frequently prescribed classes of drugs and it is estimated that approximately 50% of antibiotic use, in both... the outpatient and inpatient settings, is inappropriate. At the same time, in contrast to any other class of drugs, every antibiotic use has a potential public health consequence – inappropriate use may not harm only the individual patient, but contributes to societal harm by exerting an unnecessary selective pressure that may lead to antibiotic resistance among bacteria. This video based course will introduce learners to the basic principles of appropriate antibiotic use, demonstrate how to apply these principles to the management of common infections, and outline how to develop and maintain an antimicrobial stewardship program.
more
This module will consider the role of community pharmacy teams in tackling antimicrobial resistance. After reading this module you will be able to explain why antimicrobial resistance is a threat to patient safety, and public and global health. You will also be able to list common self-limiting infe...ctions, their usual duration, and outline the key messages that you should be sharing with the public.
more
Ce cours donnera aux cliniciens qui prescrivent régulièrement des antibiotiques les connaissances et les outils pour améliorer l’utilisation de ces médicaments essentiels dans la pratique clinique quotidienne. A l’aide d’exemples de cas, le cours mettra en évidence la façon dont les prin...cipes de bon usage des antibiotiques peuvent être appliqués à des scénarios cliniques courants. Nous verrons d’abord les connaissances cliniques fondamentales nécessaires pour utiliser correctement les antibiotiques. Puis, nous illustrerons comment les cliniciens peuvent intégrer ces connaissances dans la prise en charge des patients atteints d’infections courantes en respectant les cinq compétences principales de prescription appropriée d’antibiotiques. Ce cours fournira un cadre pour aborder chaque rencontre clinique sous l'angle de la lutte contre la résistance aux antibiotiques. Nous espérons que ce cours vous servira et vous inspirera pour devenir un champion sur le bon usage des antibiotiques.
more
Learn about superbugs from a superbug itself!
This animated video explains how bacteria develop resistance to antibiotics and eventually turn into superbugs, that are resistant to most known antibiotics.
The aim of this new short course is to increase your general understanding of antibiotic resistance and help you understand how it affects different people, including you.
In 2019, an estimated 10 million individuals fell ill with tuberculosis (TB) and 3 million of them were not reported to have beendiagnosed and notified. The gap is proportionately even wider for drug-resistant TB. Of the estimated 465 000 patients with rifampicin-resistant and multi-drug resistant T...B (RR/MDR-TB), only 206 030 (44%) were diagnosed and notified.For the first time, the World Health Organization (WHO) has provided global estimates of the incidence of isoniazid resistance: in 2019, there were 1.4 million incident cases of isoniazid-resistant TB, of which 1.1 million were susceptible to rifampicin. Most of these people were not diagnosed with drug-resistant TB and did not receive appropriate treatment.
more
In this edition, the Antimicrobial Resistance chapter discusses the growing, dangerous trend of antimicrobial resistance and the potential catastrophic consequences on global health.
The Nanomaterials chapter talks about this relatively new technology and its potential impacts on the environment a...nd health.
The Marine Protected Areas chapter draws attention to the plight of our oceans and the need for more and better managed protected areas.
The Sand and Dust Storms chapter discusses the human and environmental causes of such phenomena, their health impacts which include respiratory and cardiovascular diseases and lung cancer, and the need to manage the storms through sustainable land and water management.
The Solar Solutions chapter highlights how this renewable energy could help tackle climate change and bring much needed energy to off grid settlements.
The Environmental Displacement chapter shows how the impacts of climate change are displacing people, causing them to leave their homes.
more
Call to action by the Global Leaders Group on Antimicrobial Resistance on reducing antimicrobial discharges from food systems, manufacturing facilities and human health systems into the environment.
This is the first edition of Empiric Antibiotic Guidelines, as a guidance to all medical practitioners at North Okklapa General & Teaching Hospital.
Antibiotics are critical in the management of infection and can have a significant impact in reducing morbidity and mortality. Emerging antimicrobia...l resistance has been identified as global challenge by the World Health Organization. Careful use of antibiotics targeted to likely pathogens is an important strategy in combating development of antimicrobial resistance.
more
Did you know that they are part of Antimicrobial Resistance?
Are you clear that we can all do something to avoid them?
Marcelo Barbato, intensive care physician and Director of the ICU at Hospital Maciel, the first public hospital in Uruguay with a long history in infection control, tells us.
The AMR Multi-Stakeholder Partnership Platform aims to catalyse a global movement for action against antimicrobial resistance (AMR) by fostering cooperation between a diverse range of stakeholders at all levels across the One Health spectrum. It seeks to ensure a healthier, more sustainable and resi...lient present and future in which antimicrobials are preserved as critical lifesaving medicines accessible to everyone.
more
A view of global supply chains, pressure points, and implications for antimicrobial resistance response