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South Sudan continues to struggle with a severe health crisis affecting 8.9 million people, primarily in flood- and conflict-affected regions with population movements (displacement and returns), and disease outbreaks. The nation's health system, heavily reliant on international aid, faces staffing
...
and resource shortages. Vulnerable groups, including women, children, the elderly, and those with disabilities, have limited healthcare access and face heightened risks of mortality and illness.
The life expectancy at birth (55 years) is among the lowest globally, as mortality rates remain among the highest with neonatal, infant, under-five mortality rates estimated at 39.63, 63.76 and 98.69 deaths per 1000 live births respectively, and a maternal mortality ratio of 1,223 deaths per 100,000 live births. Although some disease specific mortality rates such as TB and AIDS-related mortality have declined, mortality due to malaria and non-communicable diseases have increased over the past five years.
The main causes of morbidity remain communicable diseases; malaria, is the top cause of morbidity (64%) and mortality (45%) among outpatients, followed by pneumonia and diarrhea.20 Several Counties report malaria cases above the threshold perennially especially during the rainy seasons, affecting mainly children under five years. The last malaria indicator survey (2017) estimated malaria prevalence of 32%, 34% and 18% among children under-five, protection of civilian’s sites, and internally displaced persons, respectively.
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Background: Atherosclerotic cardiovascular diseases (ASCVD) including myocardial infarction, stroke and peripheral arterial disease continue to be major causes of premature death, disability and healthcare expenditure globally. Preventing the accumu
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lation of cholesterol-containing atherogenic lipoproteins in the vessel wall is central to any healthcare strategy to prevent ASCVD. Advances in current concepts about reducing cumulative exposure to apolipoprotein B (apo B) cholesterol-containing lipoproteins and the emergence of novel therapies provide new opportunities to better prevent ASCVD. The present update of the World Heart Federation Cholesterol Roadmap provides a conceptual framework for the development of national policies and health systems approaches, so that potential roadblocks to cholesterol management and thus ASCVD prevention can be overcome.
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ABSTRACT
More than 500 million people worldwide live with cardiovascular disease (CVD). Health systems today face fundamental challenges in delivering optimal care due to ageing populations, healthcare workforce constraints, financing, availability
...
and affordability of CVD medicine, and service delivery.
Digital health technologies can help address these challenges. They may be a tool
to reach Sustainable Development Goal 3.4 and reduce premature mortality from
non-communicable diseases (NCDs) by a third by 2030. Yet, a range of fundamental barriers prevents implementation and access to such technologies. Health system governance, health provider, patient and technological factors can prevent or distort their implementation.
World Heart Federation (WHF) roadmaps aim to identify essential roadblocks on the pathway to effective prevention, detection, and treatment of CVD. Further, they aim to provide actionable solutions and implementation frameworks for local adaptation. This WHF Roadmap for digital health in cardiology identifies barriers to implementing digital health technologies for CVD and provides recommendations for overcoming them.
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The purpose of this course is to contribute to the reduction of morbidity and mortality in children and adolescents with cancer by strengthening the capacities of healthcare professionals on the early diagnosis of cancer with concepts and learning i
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nstruments that allow them to recognize the signs and symptoms of cancer in a timely and early manner.
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The document "Global Report on Diabetes" by the World Health Organization (WHO) provides an in-depth analysis of diabetes as a global health challenge. It covers the rising prevalence of the disease, the associated risk factors, and the increasing burden on
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healthcare systems, particularly in low- and middle-income countries. The report discusses strategies for preventing Type 2 diabetes, managing diabetes effectively, and reducing complications through integrated healthcare approaches. It emphasizes the need for global action, national policies, and collaboration across sectors to address diabetes and improve health outcomes worldwide.
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The article "Cardiovascular Diseases" on Our World in Data provides an in-depth analysis of cardiovascular diseases (CVD), the leading cause of death globally. It examines CVD trends, such as the decline in mortality rates in high-income countries due to improved
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healthcare and lifestyle changes, while low- and middle-income countries experience rising CVD burdens. The article highlights major risk factors, including high blood pressure, obesity, smoking, and poor diet. It emphasizes the importance of preventive measures and access to treatment to reduce global disparities in CVD outcomes. The data-driven approach uses visualizations to illustrate the global impact and distribution of CVD.
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Community health workers (CHWs) play a vital role in facilitating social connectedness, building trust, decrease stigma, and link communities to essential healthcare and social support services. More studies are needed to understand the factors faci
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litating these interactions among CHWs, clients, and community members.
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The document, titled "Prevention and Control of Noncommunicable Diseases: Guidelines for Primary Health Care in Low-Resource Settings," provides the World Health Organization's (WHO) recommendations for managing noncommunicable diseases (NCDs) such as cancer, heart disease, diabetes, and chronic res
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piratory illnesses in low-resource healthcare settings. It outlines cost-effective interventions for early diagnosis, treatment, and prevention within primary healthcare, focusing on accessible methods for diabetes management, blood pressure control, dietary and lifestyle guidance, and essential medication use. The guidelines aim to support healthcare professionals in delivering effective NCD care where resources are limited, ultimately improving health outcomes and reducing NCD complications.
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The document, titled "Prevention and Control of Noncommunicable Diseases: Guidelines for Primary Health Care in Low-Resource Settings," provides the World Health Organization's (WHO) recommendations for managing noncommunicable diseases (NCDs) such as cancer, heart disease, diabetes, and chronic res
...
piratory illnesses in low-resource healthcare settings. It outlines cost-effective interventions for early diagnosis, treatment, and prevention within primary healthcare, focusing on accessible methods for diabetes management, blood pressure control, dietary and lifestyle guidance, and essential medication use. The guidelines aim to support healthcare professionals in delivering effective NCD care where resources are limited, ultimately improving health outcomes and reducing NCD complications.
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The OpenWHO course titled "Interventions for Noncommunicable Diseases in Primary Health Care" provides guidance on screening, detection, diagnosis, and management of major noncommunicable diseases (NCDs) such as cardiovascular diseases, type 2 diabetes, chronic respiratory diseases (asthma and chron
...
ic obstructive pulmonary disease), and early cancer detection within primary health care settings. It emphasizes delivering high-impact essential NCD interventions through a primary healthcare approach to enhance early detection and timely treatment. This course is part of the SEARO NCD PEN-HEARTS series, which includes four courses aimed at enabling learners to plan and deliver NCD services effectively.
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People with diabetes mellitus are at an increased risk for foot ulcerations as a result of poorly controlled blood glucose which may lead to gangrene. These patients are at a high risk for lower limb amputations, higher healthcare costs, and lower q
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uality of life. This course aims to cover the prevention of foot ulcers in persons with diabetes, classification of diabetic foot ulcers, diagnosis and treatment of foot infection in people with diabetes and interventions to enhance healing of foot ulcers.
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This study investigated occupational risk factors and exposure–response relationships for airway disease among health workers (HWs) exposed to cleaning agents in two tertiary hospitals in South Africa and Tanzania.
Previous studies have demonstrated an association between asthma or respiratory
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symptoms and exposure to broad categories of cleaning-related exposures in healthcare settings. However, few studies have identified the specific cleaning agents responsible for asthma and other health outcomes. Products used for medical instrument cleaning and disinfection such as glutaraldehyde, orthophthalaldehyde (OPA) and quaternary ammonium compounds (QACs) have been implicated in the causation and exacerbation of work-related asthma (WRA) and upper airway outcomes such as rhinitis.
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Economic Burden of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review
Iheanacho, I.; Zhang, S.; King, D.; et al.
International Journal of Chronic Obstructive Pulmonary Disease
(2022)
CC2
The article "Economic Burden of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review" examines the financial impact associated with moderate-to-very severe COPD. The review analyzes studies published between 2006 and 2016 that discuss
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healthcare resource utilization (HRU), direct costs, and indirect costs related to COPD, with a focus on Europe and North America. It highlights that direct costs, including hospitalizations and medical treatments, increase with the severity of COPD and the frequency of exacerbations. Multivariate analyses identify key factors driving these costs, such as comorbidities and prior treatment history. The findings underscore the significant economic burden of COPD on healthcare systems and emphasize the need for improved management strategies to reduce costs and optimize patient care.
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Global Initiative for Chronic Obstructive Lungs Disease
Global Initiative for Chronic Obstructive Lung Disease (GOLD)
Global Initiative for Chronic Obstructive Lung Disease (GOLD)
(2024)
CC2
The GOLD website is dedicated to providing comprehensive information on Chronic Obstructive Pulmonary Disease (COPD). It offers resources and guidelines for healthcare professionals and public health authorities to improve the diagnosis, management,
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and prevention of COPD worldwide. The site includes the latest reports, strategies, and updates on COPD research, emphasizing evidence-based practices for better patient outcomes. GOLD also provides educational materials, workshops, and support for implementing COPD care programs, aiming to raise global awareness and promote effective treatments for COPD.
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The document provides information on managing chronic obstructive pulmonary disease (COPD). It emphasizes the importance of recognizing early symptoms such as persistent coughing, shortness of breath, and wheezing. The guide offers practical advice, including quitting smoking, avoiding lung irritant
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s, regular consultations with healthcare providers, and seeking support from friends and caregivers. It also highlights the value of preparing for medical visits, noting symptoms, understanding risk factors, and taking notes during appointments to maximize treatment effectiveness.
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Lung health in Africa: challenges and opportunities in the context of COVID-19
Ozho, O.B.; Mbatchou Ngahane, B.H.; Zar, H.J.; et al.
American Journal of Physiology - Lung Cellular and Molecular Physiology
(2021)
CC2
The article discusses the challenges and opportunities for lung health in Africa in the context of the COVID-19 pandemic. It highlights the strain on healthcare systems, the increase in chronic respiratory diseases like asthma and COPD, and the limi
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ted resources for managing these conditions. The pandemic has exacerbated issues like delayed diagnosis and treatment, while also impacting child lung health and increasing risks for those with tuberculosis. It emphasizes the importance of leveraging global partnerships and strategies to improve healthcare infrastructure and response in Africa.
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The COPD Foundation's website provides a range of educational resources and downloadable materials aimed at helping patients, caregivers, and healthcare professionals learn more about COPD, including information on prevention, treatment, and disease
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management.
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A worldwide increase in the prevalence of asthma has been reported in recent years. With an increase in prevalence comes an increased burden of disease in terms of morbidity, mortality and compromised quality of life. The economic burden in terms of utilisation of
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healthcare resources and limitation of the earning capacity of the individuals and families is an added problem. Various indicators such as disability-adjusted life years and healthy life years have been used to define the economic burden. The data from Asian countries regarding these parameters is scarce, underlining the need for systematic studies in these countries, especially those that are resource poor. The purpose of this review is to highlight the varying prevalence of asthma in Asia and to assess the likely economic burden for the future.
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The reader acknowledges that this report is intended as an evidence-based asthma management strategy, for the use of health professionals and policy-makers. It is based, to the best of our knowledge, on current best evidence and medical knowledge and practice at the date of publication. When assessi
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ng and treating patients, health professionals are strongly advised to use their own professional judgment, and to take into account local and national regulations and guidelines. GINA cannot be held liable or responsible for inappropriate healthcare associated with the use of this document, including any use which is not in accordance with applicable local or national regulations or guidelines.
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Several challenges face asthma management in Egypt, including the high percentage of uncontrolled patients, inadequate compliance, and overuse of short-acting beta-agonists (SABAs) leading to increased asthma-related morbidity and mortality. In this regard, the recent Global Initiative for Asthma (G
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INA) recommendations included inhaled corticosteroids containing therapy for mild asthma. Local healthcare systems and healthcare professionals (HCPs) often experience practical challenges when implementing global guidelines.
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