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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

Mpox Outbreak in Uganda Situation Update - 09 October 2024

World Health Organisation (WHO) (2024) C_WHO

Uganda confirmed the first cases of mpox on 24 July 2024 following the confirmation of two case-patients from Kasese District, Bwera Hospital by the Uganda Virus Research Institute (UVRI) through a routine sentinel surveillance system. Cumulatively, 80 confirmed cases of mpox have been registered.

Birth defects surveillance training: facilitator’s guide, second edition

World Health Organisation (WHO) (2024) C_WHO

This Birth Defect Surveillance facilitator (train-the-trainer) guide 2nd edition covers foundational skills needed to begin the development, implementation and ongoing improvement of a congenital anomaly surveillance programme, whether population-based or hospital-based, in particular for countries ... more

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Manuel Qualité Service Pharmacie

Centre Hospitalièr d'Aubenas (2005) CC

Ce manuel décrit les règles et les procédures mises en place pour assurer la qualité des prestations faites par le service de Pharmacie de l’hôpital d’Aubenas. Il s’applique à toutes les prestations faites par le service de Pharmacie à destination des différents services de l’hôp... more

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Mobilisons-nous contre l'Ebola (Textes SMS)

Ministere de la Santé et de la Lutte Contre le SIDA (2014)

L’Ebola est mortel. En cas de fièvre, diarrhée, vomissement, saignement, allez vite à l’hôpital, appelez 143 ou 101. Consultez www.prevention-ebola.gouv.ci (158 caractères) L’Ebola est mortel. Lavez-vous régulièrement les mains au savon. Désinfectez tout à l’eau de javel. Signal... more

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Prise en charge clinique de la COVID-19 : orientations évolutives, 23 juin 2022
recommended

World Health Organization WHO (2022) C_WHO

Ce document d'orientation est destiné aux cliniciens qui s'occupent de patients atteints de COVID-19 à toutes les phases de leur maladie (c'est-à-dire du dépistage à la sortie de l'hôpital). Cette mise à jour a été étendue pour répondre aux besoins des cliniciens de première ligne et fa... more

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Surveillance in Post Extreme Emergencies and Disasters (SPEED)

World Health Organization, Western Pacific Office (2011)

In the last quarter of 2009, tropical storms Ketsana, Pharma and Santi poured the heaviest rainfall on Metro Manila in more than 40 years. This caused massive flooding in the National Capital Region and Region IVA. A few weeks later, the world's biggest leptospirosis outbreak reported more than 200 ... more

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Çoçukların Hastane Bakımı

World Health Organization (2005)

This is a pocket-sized manual for use by doctors, senior nurses and other senior health workers who are responsible for the care of young children at the first referral level in developing countries. It presents up-to-date clinical guidelines which are based on a review of the available published ev... more

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Ebola surveillance in countries with no reported cases of Ebola virus disease

World Health Organization (2014) C_WHO

This document provides guidelines on the establisment of early surveillance actions to be carried out in countries where no case of Ebola virus disease has been reported. An alert system should be in place at the following sites: major land border crossing with already affected countries; capital ... more

Ebola virus disease preparedness strengthening team Cameroon Country Visit 10 to 14 November

World Health Organization (2014)

The immediate objective of the country visit to Cameroon was to ensure that the country is as operationally ready as possible to effectively and safely detect, investigate and report potential Ebola virus disease cases and to mount an effective response that will prevent a larger outbreak. After te... more

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Birth defects surveillance training: facilitator's guide

World Health Organization (WHO), National Center on Birth Defects and Developmental Disabilities from the United States Centers for Disease Control and Prevention (CDC), International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR) (2015) C_WHO

The goal of this course is to provide participants with the foundational skills needed to begin the development, implementation and ongoing improvement of a congenital anomalies surveillance programme, in particular for countries with limited resources. It focuses on the methodology needed to devel... more

Child Protection

Krishanan, S.; A. Sahoo and R. Goswami Save the Children (2015) CC

The guidebook can be used by any care giver who comes in contact with children on a daily basis and who have the primary or secondary responsibility of taking care of the children. Parents, teachers, anganwadi workers, child care institutions, hospitals can use this guide-book to help a child who is... more

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Yemen: The World’s Worst Humanitarian Crisis Enters Another Year

Andrea Carboni Armed Conflict Location and Events Dataset (2018) C1

Four years after the Houthi takeover of the capital Sana’a and the beginning of the Saudi-led military intervention, there is little to suggest that Yemen will find peace in the near future. As of January 2018, the conflict has killed tens of thousands of people and displaced millions, causing wid... more

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Guidelines for Handling Decedents Contaminated with Radioactive Materials

Wood MC, DePaolo, F, Whitaker RD Centers for Disease Control and Prevention (CDC) (2007) C_CDC

Detonation of a nuclear weapon or activation of a radiological dispersal device could cause radioactively contaminated decedents. These guidelines are designed to address both of these scenarios. They could also be applicable in other instances where decedents’ bodies are contaminated with radioa... more

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Hazardous Chemicals Handbook

Phillip Carson, Clive Mumford Butterworth Heinemann (2002) C2

"The aim of this book remains as for the first edition, namely to provide an initial point of ready reference for the identification of hazards and precautions for dangerous chemicals. It is targeted not only at those in the chemical and process industries, but also anyone likely to work with che... more

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Interim Planning Guidance for Preparedness and Response to a Mass Casualty Event Resulting from Terrorist Use of Explosives

Centers for Disease Control and Prevention; US Dept. of Health and Human Services (2010) C1

The purpose of this interim guidance is to provide information and insight to assist public policy and health system leaders in preparing for and responding to an MCE caused by terrorist use of explosives (TUE). This document provides practical information to promote comprehensive mass casualty ca... more

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Malawi Emergency Obstetric and Newborn Care Needs Assessment, 2014

Ministry of Health (Malawi), USAID, UNFPA, UNICEF, Save the Children International, Clinton Health Foundation (2015) C2

In 2014, the Ministry of Health (MOH) in Malawi conducted a nationwide assessment of emergency obstetric and newborn care (EmONC) services. This cross-sectional facility-based survey used 10 data collection modules. Data collection began on 23rd September 2014 and concluded on 17th October 2014, in ... more

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Delivering quality health services: A global imperative for universal health coverage

Kieny, Marie-Paule; Evans, Timothy Grant; Scarpetta, Stefano; Kelley, Edward T.; Klazinga, Niek; Forde, Ian; Veillard, Jeremy Henri Maurice; Leatherman, Sheila; Syed, Shamsuzzoha; Kim, Sun Mean; Nejad, Sepideh Bagheri; Donaldson, Liam World Health Organization (WHO), Organisation for Economic Co-operation and Development (OECD), and The World Bank (2018) C_WHO

Poor quality health services are holding back progress on improving health in countries at all income levels.
Today, inaccurate diagnosis, medication errors, inappropriate or unnecessary treatment, inadequate or unsafe clinical facilities or practices, or providers who lack adequate training an... more

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National Strategy for Rural Water Supply, Sanitation and Hygiene (WASH), WASH in Schools and WASH in Health Facilities 2016 - 2030

Government of the Republic of the Union of Myanmar (2016) C1

The purpose of this Strategy is to set out the way to meet the needs of the rural populations for improved domestic water supply services, access to and use of improved sanitation with elimination of open defecation, and improved hygiene behaviour by the Year 2030. It also addresses water, sanitatio... more

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Guidelines for Management of Severe Acute Malnutrition (SAM) Children at Nutrition Rehabilitation Center

Government of Gujarat (GoG), Department of Health & Family Welfare, National Rural Health Mission (2012) C1

The purpose of this Operational Guideline is to support state health authorities, programme managers and health care professionals with recommendations on appropriate management of children with SAM in the health facilities. Facility based management includes setting up and managing within the healt... more

Prise en charge clinique de la COVID-19 : orientations évolutives, 23 juin 2022 recommended

Prise en charge clinique de la COVID-19 : orientations évolutives, 23 juin 2022
recommended