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Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa.
These guidelines up
...
date the recommendations that were first released in 2018 on diagnosing, preventing, and managing cryptococcal disease. In response to important new evidence that became available in 2021, these new guidelines strongly recommend a single high dose of liposomal amphotericin B as part of the preferred induction regimen for the treatment of cryptococcal meningitis in people living with HIV. This simplified regimen - a single high dose of liposomal amphotericin B paired with other standard medicines (flucytosine and fluconazole) - is as effective as the previous WHO standard of care, with the benefits of lower toxicity and fewer monitoring demands.
The objective of these guidelines is to provide updated, evidence-informed recommendations for treating adults, adolescents and children living with HIV who have cryptococcal disease. These guidelines are aimed at HIV programme managers, policymakers, national treatment advisory boards, implementing partners and health-care professionals providing care for people living with HIV in resource-limited settings with a high burden of cryptococcal disease.
more
The HIV drug resistance report 2021 summarizes findings from 38 countries that had finalized the surveys by the time of this report and shared data with WHO.
Pretreatment HIVDR to non-nucleoside reverse-transcriptase inhibitors (NNRTI) can affect
...
more than 10% of adults starting therapy and is found up to 3 times more often in people who had previous exposure to antiretroviral drugs. In addition, nearly half of infants newly diagnosed with HIV has HIVDR to NNRTI before initiating treatment.The high levels of observed NNRTI pretreatment HIVDR among emphasize the need to fast-track the transition to WHO-recommended dolutegravir-based ART.
more
Guidelines for managing advanced HIV disease and rapid initiation of antiretroviral therapy
World Health Organization (WHO)
(2017)
C_WHO
The objectives of these guidelines are to provide recommendations outlining a public health approach to managing people presenting with advanced HIV disease, and to provide guidance on the timing of initiation of antiretroviral therapy (ART) for all
...
people living with HIV.
WHO recommends that a package of screening, prophylaxis, rapid ART initiation and intensified adherence interventions be offered to everyone living with HIV presenting with advanced disease.
WHO strongly recommends that rapid ART initiation should be offered to people living with HIV following confirmed diagnosis and clinical assessment. Rapid initiation of ART is defined as within seven days of HIV diagnosis. WHO further strongly recommends ART initiation on the same day as HIV diagnosis based on the person’s willingness and readiness to start ART immediately, unless there are clinical reasons to delay treatment. more
WHO recommends that a package of screening, prophylaxis, rapid ART initiation and intensified adherence interventions be offered to everyone living with HIV presenting with advanced disease.
WHO strongly recommends that rapid ART initiation should be offered to people living with HIV following confirmed diagnosis and clinical assessment. Rapid initiation of ART is defined as within seven days of HIV diagnosis. WHO further strongly recommends ART initiation on the same day as HIV diagnosis based on the person’s willingness and readiness to start ART immediately, unless there are clinical reasons to delay treatment. more
Consolidated Guidelines on person-centred HIV patient monitoring and case surveillance
World Health Organization
(2017)
C_WHO
Guidelines
June 2017
HIV strategic information for impact
HIV & opportunistic infection treatment: Spotlight on access gaps
MSF Médecins sans Frontières
(2019)
C2
Médecins sans Frontières access campaign
Issue Brief
Accessed: 28.11.2019
China and Eurasia Forum Quarterly, Volume 6, No. 3 (2008) p. 101-128 © Central Asia-Caucasus Institute & Silk Road Studies Program
ISSN: 1653-4212
The Responsibility of the Security Council in the Maintenance of International Peace and Security: HIV/AIDS and International Peacekeeping Operations
UNAIDS (Joint United Nations Programme on HIVAIDS)
(2011)
C2
UNAIDS and DPKO non paper | 2011
HIV and AIDS in places of detention - A toolkit for policymakers, programme managers, prison officers and health care providers in prison settings
World Health Organization; United Nations office on drugs and crime (Vienna)
(2008)
C_WHO
Introduction to HIV, AIDS and Sexually Transmitted Infection Surveillance - Overview of the HIV/AIDS Epidemic with an Introduction to Public Health Surveillance
United States Department of Health and Human Services; Centers for Disease Control and Prevention (HHS-CDC); Global AIDS Program (GAP); et al.
United States Department of Health and Human Services; Centers for Disease Control and Prevention (HHS-CDC); Global AIDS Program (GAP); et al.
(2011)
C2
Participant Manual
February 2011
Edition 3.0
Clinical Aspects od HIV/AIDS
R. Bucciardini; V. Fragola; P. De Castro
Istivto Svpreriore di Santità; Tigrey Health Bureau; Casa
(2015)
C2
Toolkit 3
The first chapter provides an overview of gender and domestic violence in the HIV and AIDS discourse and their interconnect-
edness. It analyses literature regarding gender and HIV transmission, do
...
mestic violence, and HIV and AIDS. It then discusses how gender roles impact the effects of AIDS.
The second chapter outlines implications of these findings for policy and practice. This section provides a definition for mainstreaming and deals with various aspects of mainstreaming HIV, AIDS and gender.
more
HIV/AIDS in Tajikistan
U. Laukamm-Josten; L. Khotenashvili; B. Akkazieva; et al.
World Health Organization (Europe)
(2014)
C_WHO
Mid-term review of The National AIDS Programme 2011-15
October 2013
Catalysing the HIV response for adolescents
Unicef; UNAIDS
(2018)
In eastern and southern Africa
#EndAdolescentAIDS
July 2018
- A global call to action
- Case studies
- Blogs
- Next steps
Young people and the law in Asia and the Pacific: a review of laws and policies affecting young people's access to sexual and reproductive health and HIV services
UNESCO Office Bangkok and Regional Bureau for Education in Asia and the Pacific
United Nations Educational, Scientific and Cultural Education; UNFPA; UNAIDS; UNDP; Youth Lead
(2013)
C2
Guidelines for HIV and AIDS diagnosis and treatment
Ministry of Health
(2009)
C2
(Published with Decision No. 3003/QðBYT dated 19/8/2009 of the Minister of Health)
UNAIDS/99.31E (English original, June 1999)
1st revision, April 2000
Natural History of HIV Infection
Dr. F. Amond
KZN Provincial ARV; Training NRM School of Medicine; University of Kwa-Zulu Natal
(2019)
C2
Accessed: 03.09.2019
Assecced: 03.09.2019
Meeting of national HIV programme managers of Eastern European, Central Asian and non-EU/EEA countries
World Health Organization (Europe)
(2018)
C_WHO
Meeting report, 25-26 September 2017 Copenhagen, Denmark
Midterm performance evaluation of USAID’S Central Asia HIV program
United States Agency for International Development; D. Lowe, D. Hales; B. Herstad; B. Pick; A. Bolotbaeva; G. Jonboboeva
USAID (From the American People)
(2018)
C2
October 2018
This publication was produced at the request of the United States Agency for International Development. It was prepared independently by David Lowe, David Hales, Britt Herstad, Billy Pick, Aisuluu Bolotbaeva, and Gulgun Jonboboeva.
