Promoting People's Health to Enhance Social-economic Development
This content is from the Advance Chapters of the NEW Where There Is No Doctor
Towards a Healthier Botswana
The limitation of a single sector approach. HNP Discussion Paper
Antimicrobial Resistance and our Food Systems - Challenges and Solutions
Front. Public Health, 04 June 2021 | https://doi.org/10.3389/fpubh.2021.618234
Pathogens . 2021 Nov 16;10(11):1493.doi: 10.3390/pathogens10111493
.Chronic manifestations of Chagas disease present as disabling and life-threatening condi-tions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mech...anisms underlying Trypanosoma cruzi’s infection and the host-parasite interactions that follow, prompt diagnosis and treatment remain a challenge, particu-larly in developing countries and also in those where the disease is considered non-endemic. This review intends to present an up-to-date review of the parasite’s life cycle, genetic diversity, virulence factors, and infective mechanisms, as well as the epidemiology, clinical presentation, diagnosis, and treatment options of the main chronic complications of Chagas disease.
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