Despite a historical association with poor tolerability, a comprehensive review on safety of antileishmanial chemotherapies is lacking. We carried out an update of a previous systematic review of all published clinical trials in visceral leishmaniasis (VL) from 1980 to 2019 to document any reported ...serious adverse events (SAEs).
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CEPI is seeking to raise $3.5 billion to implement CEPI’s next 5-year plan. To mitigate the immediate threat of COVID-19 variants, it is activating key elements of this plan now—and seeking to mobilise a portion of this $3.5 billion in 2021. We ...have already launched R&D programmes to initiate development of next-generation vaccines against COVID-19 variants and we are planning studies to answer critical scientific questions related to the durability of immunity, effectiveness of mixed-vaccine regimens, and vaccine effectiveness in vulnerable populations such as pregnant women. We are also bringing forward our plans to develop vaccines that could protect against multiple COVID-19 variants and other coronavirus specie
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The guidance in this publication consists of generic definitions and methodologies for the characterization of extreme weather and climate events. This publication contribute to ensuring consistent ...exchange of information that underpins the WMO State of the Climate Reports, Climate Watches, climate change studies and other emerging applications.
The purpose of the present guidelines is not to change the practice at the national level. Instead, it provides guidance for generic definitions, which are useful in contributing to WMO State of the Climate reports, climate watches, climate change studies and other emerging applications, including the recently adopted methodology for cataloguing hazardous events (WMO-CHE). These applications require regional and/or international exchange of information on extreme events.
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Today, more children than ever before are displaced within their own countries. Their harrowing stories of displacement are unfolding every day, and with increasing frequency. At the end of 2019, approximately 45.7 million people were internally dis...placed by conflict and violence (Fig. 1.1). Nearly half – 19 million – were estimated to be children. And millions more are displaced every year by natural disasters.
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This report addresses the future of basic education, ICT use in deprived locations, and the use of ICTs in primary school learning in 2020 and 2025, especially in deprived contexts. It draws on rese...arch evidence from the literature, the authors’ experiences of ICT use in education initiatives, interviews with practitioners and academics, a workshop, and consultations with Save the Children staff from many different countries, mostly conducted in August 2017
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The current effort on fighting COVID-19 cannot conceal the fact that climatic and geological hazards affect Latin-America and the Caribbean every year. At a time when countries of the region are act...ively responding to the pandemic, they also need to prepare for and implement actions to mitigate the potential impacts of other recurrent hazards. For instance, countries like Guatemala and El Salvador have been recently hit by tropical storm Amanda and, as the Caribbean region faces its annual hurricane season, countries are enhancing climate-hazard preparedness. Many countries are bracing for a two-tier crisis as they grapple with complicated logistics, limited resources and scant supplies.
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The Pharmaceutical Forum of the Americas (PFA) has previously published guidelines and organised campaigns for community pharmacists on the prevention, detection and control of arbovirus infections ...in 2018 with a grant from the FIP Foundation for Pharmacy Education and Research. Building on that expertise, FIP joined efforts with the PFA and is now publishing its first-ever handbook to support pharmacists in the
area of vector-borne diseases. As the integration of the regional forums in FIP advances, such collaborative projects are tangible results of an increasingly regionally informed and regionally targeted work by FIP.
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How to respond to, mitigate, and prevent risks to children’s protection and well-being is a profound, if unanswered, question. Practitioners agree that it is necessary to develop or strengthen pro...tective factors at multiple levels, such as the family, community, and national levels.
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Speech of the President of Caritas Internationalis to the FAO regarding food loss and responses from Caritas
This curriculum will help you, and your community, understand the science of the virus that causes COVID-19 and other viruses like it. It will help you to figure out how this virus is impacting or a...ffecting you or may impact you in the future. It will help you to understand the actions that you can take to keep yourself and your community safe.
It is available in 15 languages. Download for free at the website
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It describes and analyzes the theoretical-practical incidences of misinformation, disinformation, and malinformation, including but not limited to the Information Science framework. ...Besides, it aims to outline an understanding of these three concepts based on 16 arrangements interconnected according to their intentionality.
Conclusions: We highlight that the complexity that permeates the various fields in the present situation is due to the difficulty of reaching a consensus on the semantic definition of the concepts of information, misinformation, and its disambiguations since these concepts have various properties.
Also available in: Portuguese
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The 2013 RMIS is a nationally representative, household-based survey that provides data on malaria indicators, which are used to assess the progress of a malaria control program. The primary objective of the 2013 Rwanda Malaria Indicator Survey (2013 RMIS) was to provide up-to date information on th...e prevention of malaria to policymakers, planners, and researchers.
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The GCF aims to support developing countries in achieving a paradigm shift to low-emission and climate-resilient pathways. This is achieved by funding innovative and transformative lowemission (miti...gation) and climate-resilient (adaptation) projects and programmes developed by the public and private sectors to contribute to the implementation of national climate change priorities in developing countries. While it is relatively easy to tell what a mitigation project or programme is (i.e. its contribution to the reduction of greenhouse gases in the atmosphere, and/or whether it increases the capacity of an ecosystem to absorb them), the blurred line between a general development project and an adaptation project has been a contentious issue in the international climate finance debate. The relevant question is not whether a project is (also) a development project, but whether the project contributes to adaptation (i.e. what the adaptation/additionality argument is).
This toolkit helps governments and project developers understand how to fulfil the Green Climate Fund’s requirements when developing a fully-fledged funding proposal.
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Safe disposal of children’s feces is as essential as the safe disposal of adults’ feces. Th is brief provides an overview of the available data on child feces disposal in Burkina Faso and concludes with ideas to strengthen safe disposal practice...s, based on emerging good practice. Th e Joint Monitoring Programme for Water Supply and Sanitation (JMP) tracks progress toward the Millennium Development Goal 7 target to halve, by 2015, the proportion of people without sustainable access to safe drinking water and basic sanitation. Th e JMP standardized defi nition for an improved sanitation facility is one that hygienically separates human excreta from human contact.
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The Kenya Strategic AIDS Framework IV prioritises key populations for interventions