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This Tuberculosis guide has been developed jointly by Médecins Sans Frontières and Partners In Health. It aims at providing useful information to the clinicians and health staff for the comprehensive management of tuberculosis. Forms of susceptible and resistant tuberculosis, tuberculosis in child ... more
Promotion of the quality of clinical care through the identification, promotion and standardization of appropriate procedures, equipment and materials, particularly at district hospital level.
A guide for field health workers
Second Edition AIDS Medicines and diagnostics services July 2015
These guidelines provide recommendations for the non-pharmacological aspects of infection prevention and control for acute respiratory diseases (ARD) in health care. Administrative and infection controls, including early detection, isolation and reporting, and establishment of infection control infr ... more
A technical guide for sputum smear microscopy, initiated by the International Union against Tuberculosis, is designed to be an easy to use reference standard for the collection, storage and transport of sputum specimens and for the examination of sputum smears by direct microscopy. This edition incl ... more
The manual provides suggestions for implementing the checklist, understanding that different practice settings will adapt it to their own circumstances. The implementation manual is designed to help ensure that surgical teams are able to implement the checklist consistently. By following a few cri ... more

Laboratory diagnosis of Buruli ulcer

Portaels, F- World Health Organization WHO (2014) C_WHO
A manual for health care providers. This manual provides expert guidance on the laboratory techniques and procedures used in the diagnosis of Buruli ulcer, a disease caused by Mycobacterium ulcerans. Aimed at laboratory technicians and scientists working on this disease, the manual details the exac ... more
4th edition The WHO Laboratory Biosafety Manual (LBM) has been in broad use at all levels of clinical and public health laboratories, and other biomedical sectors globally, serving as a de facto global standard that presents best practices and sets trends in biosafety. LBM encouraged countries t ... more
The Ministry of Health of Saudi Arabia has developed the guidelines to meet the urgent need for up -to-date information and evidence-based recommendations
Ebola Virus Disease Outbreak Response Plan in West Africa July to December 2014. Annex 1
Ebola Virus Disease Outbreak Response Plan in West Africa. Annex 2
of highly contagious viruses (of the Ebola or Marburg type) in the context of an epidemic outbreak in West Africa
CDC course for volunteers going to Africa. Please find out mor infos on the CDC website
This document provides guidelines on the establisment of early surveillance actions to be carried out in countries where no case of Ebola virus disease has been reported. An alert system should be in place at the following sites: major land border crossing with already affected countries; capital ... more
Interim Recommendation published 19 September 2014. These recommendations reflect current understanding of Ebola virus disease (EVD) and are intended for national laboratory staff performing diagnostic testing to detect Ebola virus.
Steps on how to safely collect oral swabs (saliva) from deceased patients suspected to be infected with Ebola: before entering patient’s room, how to put on and remove personal protective equipment (PPE), how to collect oral swab from deceased patient and how to prepare VTM collection tube for tra ... more
PLoS One. 2012; 7(4): e29656. Published online 2012 Apr 20. doi: 10.1371/journal.pone.0029656
Community Care Centres (CCCs) are small facilities (10 beds maximum), located within the community and run by community health workers. CCCs provide isolation facilities for Ebola patients in order to prevent further transmission of the virus within their households and communities. People with Ebol ... more
Interim emergency guidelines
Morbidity and Mortality Weekly Report (MMWR) Early Release Vol. 64 ; 1 May 2015
PQDx 0183‐060‐00 WHO PQ Public Report October/2016, version 5.0
A new version is published in 2014
A Practical Guide.
Revised National Tuberculosis Control Programme
Annex to Selection and use of Ebola in vitro diagnostic assays
English version
Interim guidelines developed by CDC for healthcare providers in the United States caring for infants born to mothers who while pregnant traveled to or resided in an area with Zika virus transmission. These guidelines include recommendations for the evaluation, testing, and management of infants with ... more
Updated 6 September 2016. This guidance has been developed to provide advice on the prevention of potential sexual transmission of Zika virus. The primary transmission route of Zika virus is via the Aedes mosquito. However, sexual transmission of Zika virus may also be possible, with limited evidenc ... more
The aim of this handbook is to provide network members and other laboratories involved in the diagnosis of tuberculosis, with an agreed list of key diagnostic methods and their protocols in various areas of TB diagnosis, ranging from microbiological diagnosis of active TB to the diagnosis of latent ... more
Working document from an informal consultation of experts. A Protocol for risk assessment at the field level. The purpose of document is to provide guidance on the methodology to be used for assessing, at field level, the yellow fever virus circulation in areas at risk, and is primarily intended fo ... more
The Lancet Global Health 2016 Published Online August 30, 2016 http://dx.doi.org/10.1016/S2214-109X(16)30175-9
July 2016
2nd edition
This manual describes some of the strategic, managerial, financial, technical and scientific aspects to be considered in establishing a national EQA programme for clinical laboratories and other testing services at all health care levels
The purpose of this document is to provide interim guidance to laboratories and stakeholders involved in laboratory testing for Middle East respiratory syndrome coronavirus (MERS-CoV).
3rd edition
This resource consists of technical guidelines for District Medical Officers, counselors and laboratory technicians for second-line antiretroviral therapy drugs, operational guidelines for pilot roll-out in two centres and laboratory guidelines for viral-load testing and standard operating procedure ... more
Interim Guidance
Interim Technical Note

Scaling-Up Access to HIV Viral Load Testing (Botwana)

Mine, M. MASA, Ministry of Health, Gabarone, Botswana (2016) C2
Viral Load Scale-up and Decentralized Testing Experience in Botswana. This AIDS 2016 presentation highlights how Botswana’s decentralized testing model provides an example of how “taking the services closer to the people, rather than people coming to the services” can increase access, when s ... more
Third Edition: Revised October 2012
Policy framework.
User manual.
Policy statement.
Manual for Early Implementation
This is a basic form for reporting individual cases of plague. It asks for information regarding patient history and the course of the illness. In addition, it offers space for laboratory results, the case status, and epidemiological information.
Information note.
This information note provides a strategic overview of key implementation considerations for diagnostic integration using these devices, and is primarily intended for use by national laboratory services and TB, HIV, and hepatitis programme managers.
It may also be of inte ... more
(updated December 2014).
Training for staff working at DR-TB management centres. Training modules
Guidelines for Handling Temperature Sensitive Vaccines and Pharmaceuticals
Federal Bureau of Prisons Clinical Practice Guidelines January 1010