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EPI 2: First-line anti-epileptic medication for management of acute convulsive seizures, when intravenous access is available [2015]

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: In adults with acute convulsive seizures, where intravenous access is available, which first-line anti- epileptic medication should be used to abort seizures when compared to comparator?
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EPI 5: Anti-epileptic medicines for medication resistant convulsive epilepsy. [New 2015]

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: For adults and children with medication-resistant convulsive epilepsy, which anti-epileptic medications produce benefits and/or harm in the specified outcomes when compared to a placebo or a comparator?
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EPI 4: Antiepileptic medications for adults and children with HIV

World Health Organization WHO (2015) C_WHO
Scoping Question: For adults and children living with HIV, which antiepileptic medications (such as phenobarbital, phenytoin, carbamazepine or valproic acid) produce benefits and/or harms when compared to a placebo or controls?
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EPI 3: Anti-epileptic medications for management of established status epilepticus [Updated 2015]

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: In adults with established status epilepticus (i.e., seizures persisting after the first-line treatment with benzodiazepines [or benzodiazepines-resistant status epilepticus]), which anti-epileptic medications are associated with cessation of seizures and reduced adverse effects)? ... more
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Psychosocial interventions for the management of cannabis dependence [Updated 2015]

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: Which psychosocial interventions are effective in the management of cannabis dependence?
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Psychosocial interventions for the management of psychostimulant dependence (2015)

World Health Organization WHO mhGAP; WHO (2015) C_WHO
SCOPING QUESTION:Which psychosocial interventions are effective in the treatment of psychostimulant dependence for adults and young people?
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Supervised dosing with a long acting opioid medication for the management of prescription opioid dependence (New 2015)

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: In the management of prescription opioid dependence, does supervised dosing with a long-acting opioid medication result in less opioid use and related harms than non-prescription, detoxification or usual care?
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Role of depot antipsychotic medication in long-term antipsychotic treatment

World Health Organization WHO (2015) C_WHO
Q5.SCOPING QUESTION: In individuals with psychotic disorders (including schizophrenia) who require long-term antipsychotic treatment, what is the safety and role of depot antipsychotic medication?
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Comparative effectiveness of different formats of psychological treatments for depressive disorder
recommended

World Health Organization WHO WHO (2015) C_WHO
Q8.SCOPING QUESTION: In adults and older adolescents with depressive disorder, what is the comparative effectiveness of different formats of psychological treatments?
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CH 4: Antidepressants among adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective

World Health Organization (2015) C_WHO
(2015) Scoping question: Are antidepressants (specifically, tricyclic antidepressants and selective serotonin reuptake inhibitors) effective and safe in adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective?
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CH 5: Effective strategies for detecting maltreatment of children and youth within the context of mental health and developmental assessment.

World Health Organization (2015) C_WHO
(New 2015) Scoping question: Within the context of mental health and developmental assessment of children and youth, what are the effective strategies for detecting maltreatment?
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CH 1: Caregiver skills training for the management of developmental disorders

World Health Organization (2015) C_WHO
(Updated 2015) Scoping question: What is the effectiveness of caregiver skills training in the management of children and adolescents with developmental disorders?
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EPI 1: Antiepileptic medications for management of acute convulsive seizures when no intravenous access is available

World Health Organization WHO (2015) C_WHO
[Updated 2015] Scoping Question: In adults with acute convulsive seizures in first-level care or in the community (when no IV access is available), which antiepileptic medications produce benefits and/or harm when compared to comparator?
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CH 3: Psychosocial interventions, treatment of emotional disorders.

World Health Organization (2015) C_WHO
[Updated 2015] Scoping question: What is the effectiveness of psychosocial interventions, including caregiver skills training, for emotional disorders in children and adolescents?
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CH 2: Psychosocial interventions for treatment of behavioural disorders.

World Health Organization (2015) C_WHO
[Updated 2015] SCOPING QUESTION: What is the effectiveness of psychosocial interventions (including caregiver skills training) for behavioural disorders in children and adolescents?
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School-based interventions in reducing deaths from suicide and suicide attempts among young people

mhGAP; World Health Organization (2015) C_WHO
(New 2015) Scoping question: In school students aged 14-­‐‑15 years, are school-­‐‑based interventions effective in reducing deaths from suicide and suicide attempts compared to care-­‐‑as-­‐‑usual?
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Risk factors of Cholera mortality

Global Task Force On Cholera Control (GTFCC) (2022) CC
To better adapt current case management practices and address excess mortality in otherwise treatable cases will require better knowledge of the demographic characteristics of the patients and comorbidities which can make severe dehydration harder to tolerate physiologically. With this in mind, a ... more
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Antipsychotics and mood stabilizers (lithium, valproate, or carbamazepine) for maintenance treatment of bipolar disorder

World Health Organization WHO (2018) C_WHO
Q8. SCOPING QUESTION: In people with bipolar disorders who require maintenance treatment, are a) antipsychotics or b) mood stabilizers (lithium, valproate or carbamazepine) effective and safe?
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Pharmacological interventions in adolescents with psychotic disorders
recommended

World Health Organization World Health Organization (2015) C_WHO
Q15. SCOPING QUESTION: Is pharmacological intervention effective and safe for treatment of psychotic disorders in adolescents (including schizophrenia and bipolar disorder)?