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National Tuberculosis and Leprosy control Program
3rd edition.
Guidelines for treatment of drug-susceptible tuberculosisand patient care 2017 Update
Guidelines for treatment of drug-susceptible tuberculosis and patient care Uptsate 2017
Aлгоритм лабораторной диагностики и мониторинга лечения туберкулеза легких и туберкулеза с лекарственной устойчивостью на основе применения современных быстрых ... more
Policy Guidance.
Accessed November 2017
Interim policy guidance.
End TB. Accessed in November 2017.
Lessons from the STEP-TB Project. Accessed November 2017.
Antimicrobial Resistance and Infection Control 2014,3 :31
Version 1.0, 2014-11-21 Introduction: This document lists TB indicators that can be derived from the recording and reporting tools defined in Definitions and reporting framework for tuberculosis – 2013 revision (WHO/HTM/TB/2013.2). Geneva, World Health Organization; 2013. (http://www.who.int/t ... more
(updated December 2014).
The END TB strategy
Report: A survey conducted among the 27 high MDR-TB burden countries. March – July 2015 Stop TB Partnership in collaboration with Medecins Sans Frontieres (MSF). Accessed November 2017.
Progress in diagnosis: Akey in overcoming the MDR-TB crisis. The expanse-TV project progress and impact brief.
PLOS ONE | DOI:10.1371/journal.pone.0133869 July 28, 2015, p.1-16
Information note Accessed November 2017.
Accessed November 2017

Prevalence of drug-resistant tuberculosis in Nigeria: A systematic review and metaanalysis

C. C. Onyedum, I. Alobu, K. N. Ukwaja PLOS One; O. Neyrolles (Institut de Pharmacologie et de Biologoie Structurale) (2017) CC
PLoS ONE 12(7): e0180996. https://doi.org/10.1371/journal.pone.0180996
Fact sheet -Updated November 2015
National Guidelines for HIV & AIDS Care and Treatment (5th Edition)
Accessed November 2017

Training Package on XPERT MTB/RIF

USAID; WHO; FIND; et al. global laboratory initiative (2017) C_WHO
The modules (1-12) are based on materials originally developed by FIND, KNCV and Cepheid, and are in PowerPoint format for country customization. Depending on the audience, modules may be selected and adapted according to need (e.g. basic users, supervisors, clinicians). Topics covered include: Over ... more
13280–13285 / PNAS / September 9, 2008 / vol. 105 / no. 36
HIV/TB Research Meeting; March 3, 2013
Improving the management of childhood tuberculosis within national tuberculosis programmes: research priorities based on a literature review WHO/HTM/TB/2007.381, 07.02

Controlled clinical trails in Tuberculosis

A. Jindani, A. Nunn, D. A. Enarson International Union Against Tuberculosis and Lung Disease (2004)
A Guide For Multicentre Trials in High-Burden Countries
Lancet Respir Med 2017; 5: 291–360Vol, 5 April 2017
Int. J. Mol. Sci. 2017, 18, 341, 1 - 10
54th directing council; 67th session of the regional Committee of WHO for the Americas CD54/11, Rev. 1, 2 October 2015, Original: Spanish
Copenhagen, Denmark, 24–25 August 2017
Tuberculosis MDR-TB & XDR-TB The 2008 Report

Review of the national tuberculosis programme in Belarus

P. de Colombani World Health Organization Europe (2016) C_WHO
8–18 December 2015
Medicina (Kaunas) 2013;49(7):335-40
Protocol clinic naţional PCN- 123
Eur Respir J. 2014 April ; 43(4): 1132–1141. doi:10.1183/09031936.00203613.
Epidemiologisches Bulletin; 22. August 2016 / Nr. 33 ;DOI 10.17886/EpiBull-2016-050
Comunicat de presă Accessed December 2017

Tuberculoza pulmonară (Rezumat)

Dr. O. Nicolaescu emcb (Educatie medicala continua) (2014) C2
Rezumat. Definiţie. Epidemiologie. Etiologie. Ciclul de transmitere al tuberculozei. Patogenie si imunitate. Leziuni morfologice în tuberculoză.Modul PNEUMOLOGIE 1 mai 2013 – 30 aprilie 2014]Creditat prin decizia CMR nr. 6653/21.12.2012
Western Pac Surveill Response J. 2014 Oct-Dec; 5(4): 34–46. Published online 2014 Dec 18. doi: [10.5365/WPSAR.2014.5.4.007]
15. Euro Surveill. 2017;22(47):pii=17-00103
. MSF Essential Drugs Guidelines دليل عملي موجه للأطباء والصيادلة والممرضين والمساعدين الطبيين
The WHO South-East Asia (‎SEA)‎ Region bears a high burden of tuberculosis (‎TB)‎ and MDR-TB. In 2015, the Region accounted for nearly 200 000 or 35% of the global estimated new RR/MDR-TB cases eligible for treatment. Extensively drug-resistant TB (‎XDRTB)‎ has also been reported from s ... more
Updated May 2017
This document is meant to respond to the questions:
■ What health interventions should the child receive and when should s/he receive it?
■ What health behaviours should a mother/caregiver practise (or not practise)?
National Tuberculosis Programme and Senior Paediatricians
This guideline was first developed in 2007 but further updated in 2012 and 2016 to ensure the use of the latest evidence-based international recommendations on childhood TB. The guidelines will fill the gaps in a systematic approach to T ... more
INT J TUBERC LUNG DIS 22(2):197–205 http://dx.doi.org/10.5588/ijtld.17.0245
A large meta-analysis of observational studies that provided the basis for the recent makeover of global recommendations for multidrug-resistant tuberculosis (MDR-TB) treatment shows that newer and repurposed drugs produced better outcomes and fewer deaths than older treatments. The meta-analysis ... more
Public health Panoram, Vol.2 Issue 1 March 2016
The International Journal of Tuberculosis and Lung Disease 21(5) DOI: 10.5588/ijtld.16.0518

Field Guide for the Management of Drug-Resistant Tuberculosis

A. Piubello The International Union Against Tuberculosis and Lung Disease (2018)
A practical tool to help health workers in the clinical and operational management of multidrug-resistant tuberculosis with special focus on the introduction, implementation and management of the nine-month treatment regimen.
2nd edition. The practical aspects of TB patient care from the onset of symptoms to the completion of treatment are covered in this guide
This document contains: The systematic reviews and GRADE assessments used at the Index-TB Guideline Panel in July 2015; The Evidence to Decision tables that record the Panel’s assessment and recommendations from this meeting
The Guidelines for the Diagnosis, Treatment and Prevention of Leprosy provide state-of-the-art knowledge and evidence on leprosy diagnosis, treatment and prevention based on a public health approach in endemic countries. The target audience of this document includes policy-makers in leprosy or infec ... more
This document contains a series of desk reviews for the eight ENGAGE-TB priority countries supported by the Global Fund (DRC, Kenya, Indonesia, Mozambique, Myanmar, Nigeria, Pakistan and Tanzania). The document provides a situation assessment and gap analysis about the state of community based TB ac ... more
This report presents an overview of the transition process in Azerbaijan, some sustainability aspects and challenges stemming from donor withdrawal from TB-related activities, along with recommendations on how to overcome transition-related difficulties and ensure sustainability.
The present Consolidated guidelines include a comprehensive set of WHO recommendations for the treatment and care of DR-TB, derived from these WHO guidelines documents. The consolidated guidelines include policy recommendations on treatment regimens for isoniazid-resistant TB (Hr-TB) and MDR/RR-TB, ... more
Как и руководство 2006 года, настоящий документ предназначен для специалистов, занимающихся разработкой государственных программ по борьбе с туберкулезом, педиатр ... more

Tuberculosis and HIV

UNAIDS (2019) C2
Accessed: 05.10.2019

South African National TB Guidelines - Children

Medicines Information Centre; SPES Bona; National HIV & TB Health Care Worker Hotline (2019) C2
Accessed: 08.10.2019 Based on the National Guidelines for the Management of Tuberculosis in Children 2013, Department of Health, South Africa.
July 2019 Policy brief HIV Treatment
HIV Treatment - Interim Guidance
Frontiers in Pediatrics | www.frontiersin.org 1 April 2019 | Volume 7 | Article 159
The aim of the people-centred framework is to help countries to develop fully prioritized and budgeted NSPs based on a culture of making full use of the available data, which are aligned with national planning cycles and which provide the basis for a robust national response that can accelerate prog ... more

Guideline Treatment of tuberculosis in patients with HIV co-infection

Department of Health; Queensland Government (2019) C2
Version 3.0 Accessed: 24.11.2019

Xpert MTB/RIF for people living with HIV

World Health Organization (2014) C_WHO
Technical Note on Antimicrobial Resistance This document reflects UNICEF’s response to the growing global threat of AMR to child survival, growth and development. It identifies UNICEF’s AMR-specific and AMR-sensitive actions in reducing infections, promoting access to and optimal use of antimic ... more
Research Article PLOS ONE | DOI:10.1371/journal.pone.0164619 October 13, 2016
HIV i-Base July 2018
Médecins sans Frontières access campaign Issue Brief Accessed: 28.11.2019

Transition to new antiretrovirals in HIV programmes

World Health Organization (2017) C_WHO
HIV Treatment Policy Brief July 2017
Technical Update HIV Treatment July 2017
Le défi des pays en voie de développement est la disponibilité de méthodes de diagnostic rapide et précis pour le management de la tuberculose. Des techniques moléculaires offrent cet avantage et nous avons utilisé le test GeneXpert MTB/RIF dans le diagnostic de la tuberculose extra-pulmonair ... more
Stop TB Partnership
Tuberculosis treatment failure results in increased risk of morbidity, drug resistance, transmission and mortality. There are few data about tuberculosis treatment outcomes in Burkina Faso. The current study investigated the factors associated with tuberculosis treatment failure in the central east ... more
The consolidated guidelines are complemented by an operational handbook which is designed to assist with implementation of the WHO recommendations by Member States, technical partners and others who are involved in the management of patients with DR-TB. The WHO Operational Handbook on Tuberculosis, ... more
Meeting Report 27-29 October 2020 The overall goal of the meeting was to discuss recent changes in treatment regimens and diagnostics for drug-resistant TB and to determine how these impact on the definition of XDR-TB, with a view to revising this definition. The pre-existing definition of XDR-TB w ... more
2nd edition. Children with TB comprise about 10-12% of the total TB cases diagnosed in the country. This burden is likely to be higher given the challenges in diagnosing TB in children. The symptoms of TB in children mimic those of other childhood diseases. Children do not readily expectorate and th ... more
The 2020 recommendations for the programmatic management of TB preventive treatment are the first to be released under the rubric of WHO consolidated TB guidelines (Module 1 – Prevention). The WHO consolidated TB guidelines will gradually group all TB recommendations and will be complemented by ma ... more
100 test methods for 100 active pharmaceutical ingredients For existing Minilab projects that want to replace old manuals or initiatives that want to start new projects, the new "Minilab Edition 2020" can be obtained at the preferential price of 50 € from our logistic partner Technologie Transfer ... more
13 May 2021 To avoid a reversal of progress from the adverse impacts of the COVID-19 pandemic, new knowledge and lessons from successful programmatic innovations are urgently needed to improve TB prevention and care. Experience can provide evidence for innovative approaches and strategies to mainta ... more