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1
This algorithm is addressed to laboratories with established capacity(molecular, antigenic and/orserological) to detect dengue (DENV), Zika (ZIKV), and chikungunya(CHIKV) as part of the differential diagnosis for arborviruses. A BSL2 containment level is required to handle suspected samples.
The National Guidelines for HIV-1 Viral Load Laboratory Testing support plans to scale up viral load (VL) testing to reach the 90-90-90 targets in India. This phased scale-up includes the setup of 70 additional VL testing laboratories nationally. Th ... more
Second Edition AIDS Medicines and diagnostics services July 2015
This document aims to present an algorithm for deciding whom to test and provide guidance on the laboratory tests for Zika virus infection diagnosis in order to support clinical diagnostic and case reporting through surveillance among EU Member Stat ... more
Information note.
This information note provides a strategic overview of key implementation considerations for diagnostic integration using these devices, and is primarily intended for use by national laboratory services and TB, HIV, and hepati ... more
Ethiopia Antimicrobial Resistance Surveillance Plan
OBJETIVO DE LA GUÍA Describir los lineamientos técnicos de la vigilancia de tuberculosis por el laboratorio, así como los procesos de obtención, recolección, procesamiento, transporte y conservación de muestras, y las funciones que se realizan y articulan por todos los integra ... more
Cholera is a transmissible diarrhoeal infection caused by Vibrio cholerae. Endemic and/or epidemic in over 40 countries (mainly in Africa and Asia), cholera continues to be a major global public health issue. The World Health Organization (WHO) estimates that the number of cases reported worldwid ... more
5th edition
Many critical questions remain about the effectiveness of COVID-19 vaccines in real-world settings. These questions can only be answered in post-introduction vaccine effectiveness studies.This guidance document outlines an approach to leverage existing surveillance systems for Severe Acute Respirato ... more
Website last accessed on 04.06.2023
3rd Edition – July 2017 www.msfaccess.org

Training Package on XPERT MTB/RIF

USAID; WHO; FIND; et al. global laboratory initiative (2017) C_WHO
The modules (1-12) are based on materials originally developed by FIND, KNCV and Cepheid, and are in PowerPoint format for country customization. Depending on the audience, modules may be selected and adapted according to need (e.g. basic users, supervisors, clinicians). Topics covered include: Over ... more

Module de formation sur XPERT MTB/RIF

USAID; WHO; FIND; et al. global laboratory initiative (2017) C_WHO

Pacote de formação sobre o Xpert MTB/RIF

USAID; WHO; FIND; et al. global laboratory initiative (2017) C_WHO
The modules (1-12) are based on materials originally developed by FIND, KNCV and Cepheid, and are in PowerPoint format for country customization. Depending on the audience, modules may be selected and adapted according to need (e.g. basic users, supervisors, clinicians). Topics covered include: Over ... more
Комплект учебных материалов по Xpert MTB/RIF The modules (1-12) are based on materials originally developed by FIND, KNCV and Cepheid, and are in PowerPoint format for country customization. Depending on the audience, modules may be selected and adapted according to nee ... more
Iniciativa Global de Laboratorio – Entrenamiento en Xpert MTB/RIF Accessed December 2017 Por favor descargue los 12 módulos todos
This guide includes information relevant for tuberculosis (TB) program and laboratory managers, as well as Ministry of Health officials across disease programs interested in establishing integrated solutions for specimen referral. Though TB-focused ... more
October 2018
Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information. COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv
SARS-COV-2 antigen rapid diagnostic tests are an alternative option for diagnosing active SARS-CoV-2 infection through detection of viral proteins. Rapid antigen tests revolutionize the response to COVID-19 by providing accurate test results in 10 to 20 minutes instead of days, allowing tests to be ... more
ASLM strives to keep laboratory networks in Africa connected and informed of diagnostic tools, techniques, procedures and advancements related to COVID-19 testing with interactive training and information sessions using the Extended Community Health ... more
The NOAA Physical Sciences Laboratory (PSL) conducts research to improve observations, understanding, modeling and predictions of weather, water and climate extremes, and their related impacts.
Persons with acute respiratory illness with sudden onset of at least one of the following: cough, sore throat, shortness of breath or fever [≥ 38°C (measured) or history of fever (subjective)] irrespective of admission status AND In the 14 days prior to onset of symptoms, met at least one of the ... more
Quick reference guide
Prequalification of Male Circumcision Devices PQMC_007 v1 16 December 2011
The trematodes Fasciola hepatica (also known as the common liver fluke or the sheep liver fluke) and Fasciola gigantica are large liver flukes (F. hepatica: up to 30 mm by 15 mm; F. gigantica: up to 75 mm by 15 mm), which are primarily found in domestic and wild ruminants (their main definitive host ... more
Accessed 3rd of October 2015
Hep B Help colates a number of Hepatitis B fact sheet and other resources for patient education. Accessed 13th of November 2015.
User manual.
ПРИЛОЖЕНИЕ ДЛЯ СОСТАВЛЕНИЯ БЮДЖЕТА. РУКОВОДСТВО ПОЛЬЗОВАТЕЛЯ.
FAST FACTS FROM THE 2013-14 ZAMBIA DEMOGRAPHIC AND HEALTH SURVEY
he Framework sets the requirements for facilities handling High Consequence Agents and Toxins (HCATs) and guides the implementation of laboratory biosafety and biosecurity practices associated with the design, commissioning, routine operation safe a ... more
Laboratory monitoring & evaluation tool Xpert Pre-installation Checklist Accessed December 2017
User Guide. This Laboratory Assessment Tool (LAT) is specifically designed to assess capacities of existing laboratories which have implemented or aim to implement SARS-CoV-2 testing. It addresses both core capacities of a ... more
The speed of developing diagnostics for SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19), has been quite remarkable. Diagnostics have focused on nucleic acid amplification testing (NAAT) to identify infected individuals in acute-phase disease for timely implementation of mitiga ... more
This document outlines minimum requirements of laboratory testing for COVID-19 and link laboratory testing with surveillance and contact tracing to guide the outbreak response by national health aut ... more
Laboratory Safety Handbook. Global edition Las pruebas de cultivo y sensibilidad a fármacos son necesarias especialmente para los pacientes con riesgo de tuberculosis resistente a los medicamentos y para vigilar su respuesta al tratamiento. Si b ... more
The WHO BioHub Biosafety & Biosecurity: criteria and operational modalities sets out the requirements to which laboratories wishing to receive biological materials as part of this international exchange system should abide, to ensure safe and secure operations. These provisions are in accordance wit ... more
The meeting was held from 26 to 27 March 2018 to review and discuss the following topics: Advances and challenges in the use of fTLC, and new approaches to detecting mycolactone using monoclonal antibodies (mAbs). The status of development of rapid diagnostic tests (RDTs) targeting the MUL ... more

Tobacco product regulation

World Health Organization; Together lets beat Tobacco (2018) C_WHO
Building laboratory testing capacity
DPDx - Laboratory Identification of Parasites of Public Health Concern Trypanosoma cruzi, is a parasitic protozoan that is the causative agent of Chagas disease (American trypanosomiasis). Currently, six distinct lineages of T. cruzi are classified ... more
When is laboratory testing for Zika Virus infection reasonable? Testing algorithm for patients with and without symptoms.
African Journal of Laboratory Medicine | Vol 7, No 2 | a796 | 06 December 2018
African Journal of Laboratory Medicine | Vol 7, No 2 | a770 | 06 December 2018
The microbiology laboratory database software. WHONET is a desktop Windows application for the management and analysis of microbiology laboratory data with a particular focus on antimicrobial resis ... more
Since the World Health Organization (WHO) launched the Global Antimicrobial Resistance Surveillance System (GLASS) in 2015, there has been rapidly growing awareness among many African countries that they need to be doing more to combat antimicrobial resistance (AMR). The Africa Centres fo ... more
Limited coverage of laboratory services and long turnaround times from real-time reverse transcription-polymerase chain reaction (rRT-PCR) for the detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been insufficient to mee ... more
Protocol for laboratory diagnosis of COVID_19, in the framework of the health emergency
This training toolkit by the European Laboratory Initiative for TB, HIV and Viral Hepatitis provides a unique combination of practical guidance and expert advice on the interpretation of selected WHO-endorsed tests for drug-resistant tuberculosis (D ... more
To meet the need for laboratory diagnosis to be integrated in community care, the new 2022 Update describes point-of-care tests that can be performed both in district laboratories and peripheral healthcare facilities by non-specialist staff. Also in ... more
This online training is based on the Global Laboratory Initiative’s “Guide for providing technical support to TB laboratories in low- and middle-income countries”. This guide is intended to familiarize those who are providing technical assista ... more

Diagnostics Catalog August 2018

Global Drug Facility World Health Organization WHO, Stop TB (2018) C_WHO
Stop TB`s GDF provides a wide range of diagnostic equipment and laboratory supplies in its Diagnostics Catalog
Practical guide for doctors, nurses,laboratory technicians, medical auxiliaries,water and sanitation specialists and logisticians
The latest update (28 January 2021) includes the following addition and revision: biosafety aspects for working with antigen-detecting rapid diagnostic test; handling new variants of SARS-CoV-2 in the laboratory; updated assay decon ... more
The latest update (28 January 2021) includes the following addition and revision: biosafety aspects for working with antigen-detecting rapid diagnostic test; handling new variants of SARS-CoV-2 in the laboratory; updated assay decon ... more
How does environmental health services work with epidemiology and laboratory professionals to protect public health? Learn how environmental health services answer how and why a disease occurs, recommend actions to stop outbreaks and prevent future ... more
The objective of the study was the validation and implementation of GeneXpert MTB/RIF for routine use in the rapid detection of tuberculosis and sensitivity to rifampicin in clinical samples; for this, 1592 respiratory samples were collected and analyzed in the ... more
This manual is to assist health care providers and laboratory scientists to diagnose mycobacterium ulcerans disease (Buruli ulcer). The manual aims to achieve a better understanding of the clinical presentation and its diagnosis. The methods describ ... more
This manual is designed primarily to assist managers of national malaria programmes and national reference laboratory responsible for quality assurance of malaria microscopy control. The information is also applicable to non-governmental organizatio ... more
Department of Technical Support Services, Division of Laboratory Services, Ministry of Health
The Government of the Democratic Republic of the Congo announced today that preliminary laboratory results indicate a cluster of cases of Ebola virus in North Kivu province. The announcement was issued little more than a week after the Ministry of H ... more
This document provides countries with recommendations for structuring a public health entomology laboratory network. The document will help countries to identify their areas of need and determine how the entomology network can be strengthened, espec ... more
In this unit we will learn about COVID-19 and Testing - the role of the laboratory in the pandemic. Jesuit Worldwide Learning invites you to learn facts and test your knowledge on the ongoing pandemic caused by Coronavirus (COVID 19) through a fun- ... more
Practical guide for doctors, nurses,laboratory technicians, medical auxiliaries,water and sanitation specialists and logisticians. Online version
This publication aims to provide updated guidance on the specific use of yellow fever laboratory assays in the context of surveillance to be used across the Global Yellow Fever Laboratory Network fo ... more

Management of a Measles Epidemic

Corinne Danet, and Florence Fermon Médecins Sans Frontières (2013) C1
Practical guide for doctors, nurses, laboratory technicians, medical auxiliaries and logisticians
This resource consists of technical guidelines for District Medical Officers, counselors and laboratory technicians for second-line antiretroviral therapy drugs, operational guidelines for pilot roll-out in two centres and ... more
Prepared as an outcome of ICMR Expert Group on Immunophenotyping of Hematolymphoid Neoplasms | Coordinated by Division of Non Communicable Diseases | This document addresses on various issue related to good quality practices in laboratory work up of ... more
School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Shanghai, China PLOS ONE | www.plosone.org 1, May 2013 | Volume 8 | Issue 5 | e64915
This is a case-ascertained prospective investigation of all identified health care contacts working in a health care facility in which a laboratory confirmed 2019-nCoV infected patient (see 2.2 Study population) receives care. Note that this study c ... more
The household transmission investigation is a case-ascertained prospective study of all identified household contacts of a laboratory confirmed 2019-nCoV infection (see 2.2 Study population). It is intended to provide rapid and early information on ... more
Outline • Welcome and objectives • Microbiology, epidemiology and clinical presentation • Surveillance for imported cases including case definitions • Laboratory diagnosis • Infection prevention and hospital readiness • Patient ... more
This study addresses part of the Terms of Reference for a scoping report ‘An analysis of approaches to laboratory capacity strengthening for drug resistant infections in low and middle income countries’. It has been produced as a separate report ... more
Interim guidance, 6 October 2021 Direct detection of SARS-CoV-2 viral proteins (antigens) in nasal swabs and other respiratory secretions using lateral flow immunoassays (also known as rapid diagnostic tests, RDTs) offers a faster and less expensive method to test for SARS-CoV-2 than the reference ... more
Genomic sequencing has been an essential tool in generating virological data, driving the laboratory response, and better understanding the dispersal and evolutionary patterns of SARS-CoV-2. In addition to the characterization of the global circulat ... more
Following review of evidence and advice from the Technical Advisory Group (TAG) on Tuberculosis (TB) Diagnostics and Laboratory Strengthening, the World Health Organization (WHO) announces that current WHO recommendations for the use of interferon- ... more
This document aims to provide interim guidance for microbiology and virology experts, other laboratory professionals, laboratory managers, infectious disease programme managers, public health profes ... more
As of 14 December 2021, a total of 19 laboratory-confirmed human rabies cases has been reported in South Africa for 2021. The cases are from Eastern Cape, KwaZuluNatal and Limpopo provinces. In addition, four probable rabies cases were reported from ... more
Africa CDC Institute of Pathogen Genomics (IPG) was launched in November 2019 and operates under the Division of Laboratory Systems and Networks. IPG coordinate the implementation of molecular diagnostics, pathogen genomics and bioinformatics in Na ... more
based on the WHO Bench Aids for the diagnosis of intestinal parasites; Tutor’s Guide: perform specific laboratory techniques; identify intestinal parasites by genus and species; quantify helminth eggs in faeces by Kato-Katz procedure.
The occurrence of a case of wild polio in a previously polio free area as presently in Syria, whether through importation, laboratory accident, or mutation of vaccine virus (VDPV), should be considered a public health emergency, that requires a rapi ... more
The 6th edition of the essential medicine list has been developed based on the 5th edition list of essential medicines, the National Standard Treatment Guidelines and Protocols 2013, list of laboratory commodities and List of Consumables used in pub ... more
Ebola interventions: The intervention to combat Ebola aims to stop human-to-human transmission. The package is composed of five elements necessary to control the spread of the disease: care to patients, contact monitoring, safe burials, laboratory ... more
A survey was conducted in countries in all six WHO regions and focused on the building blocks that are considered prerequisites to combat antimicrobial resistance: a comprehensive national plan, laboratory capacity to undertake surveillance for resi ... more
The main objective of this self learning programme is to understand the purpose of biostatistics through realistic cases and to acquire basic biostatistics skills that can be applied to your work. The target audiences of this training are medical and biomedical students, ... more
This Rapid Advice Guideline updates the Interim Guidance on the “Assessment of infants with microcephaly in the context of Zika virus” published in February 2016 (WHO/ZIKV/MOC/16.3). The recommendations provides guidance on the screening, clinical assessment, neuroimaging, ... more
The overall objective of this implementation plan is to define the strategy for implementation of the Xpert MTB/RIF test for rapid detection of TB and rifampicin (RIF) resistance in Tanzania, within the context of the National Tuberculosis and Leprosy Programme (NTLP) strategic plan and other nation ... more