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Management of covid-19: a practical guideline formaternal and newborn health care providers inSub-Saharan Africa

B. N. Ezenwa, I. B. Fajolu, O. R. Akinajo, et al. The Journal of Maternal-Fetal & Neonatal Medicine (2020) CC

COVID-19 is a pandemic that is currently ravaging the world. Infection rate is steadily increasingin Sub-Saharan Africa. Pregnant women and their infants may suffer severe illnesses due to theirlower immunity. This guideline prepares and equips clinicians working in the maternal and new-born section... more

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Treatment of Leprosy

Lockwod DN. The International Textbook of Leprosy (2018) CC

This chapter discusses the antibacterial treatment of leprosy infections. Antibiotic treatment is a key component of leprosy treatment, as it is vital to prevent the progression of the infection. Treatment with rifampin and other antibiotics is highly effective and cures 98% of patients with the ... more

WHO guideline on preventive chemotherapy for public health control of strongyloidiasis
recommended

World Health Organization WHO (2024) C_WHO

Human strongyloidiasis is a chronic parasitic disease caused by infection with Strongyloides stercoralis, a soil-transmitted helminth that is estimated to infect 300–600 million people worldwide. This neglected tropical disease (NTD) is endemic globally, predominately in the South-East Asia, Afric... more

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Nepal Improving antibiotic use for UTIs in Nepal – Examples from the field

ReAct (2018) C2

This small scale project aimed to optimize antibiotic prescriptions for Urinary Tract Infections (UTI) at Okhaldhunga Community Hospital in Nepal. A review of 18 months data from urine cultures taken in the hospital was completed in 2017. Presentations about antibiotic resistance, the local bacteria... more

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Polio

Dattani, S.; F. Spooner, S. Ochmann and M. Roser Our World in Data (2022) CC

Here you can download different charts about cases by world region, prevalence rates, and progress towards polio eradication and much more. Polio is an infectious disease that is caused and transmitted by the poliovirus. Most infections do not lead to any symptoms, but—among the unvaccinated—... more

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Mitigating the impact of COVID-19 on countries affected by HIV, tuberculosis and malaria

Global fund (2020) CC

While many of the countries hit by the COVID-19 in the first few months of the year are now beginning to relax lockdown measures as infection and death rates fall, in the regions most affected by HIV, TB and malaria, such as Africa, South Asia and Latin America, the pandemic continues to accelerate.... more

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Every child alive: The urgent need to end newborn deaths

UNICEF (2018)

Globally, in low-income countries, the average newborn mortality rate is 27 deaths per 1,000 births, the report says. In high-income countries, that rate is 3 deaths per 1,000. Newborns from the riskiest places to give birth are up to 50 times more likely to die than those from the safest places.... more

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Situation Analysis and Recommendation: Antibiotic Use and Resistance in Tanzania

Aboud S., R. Mdegela Global Antibiotic Resistance Partnership—Tanzania Working Group (2015) C2

Antibiotics and other antimicrobial agents are invaluable life savers, particularly in resource-limited countries where infectious diseases are abundant. Both uncomplicated and severe infections are potentially curable as long as the aetiological agents are susceptible to the ... more

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Guidance on COVID-19 for the care of older people and people living in long-term care facilities, other non-acute care facilities and home care

World Health Organization WHO (2020) C_WHO

In response to the COVID-19 outbreak, this guidance provides information on infection and prevention control (IPC) for older people, their friends and families, carers, and healthcare providers. Anyone who manages, works, volunteers or provides care at any type of facilities where older people recei... more

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Emergency Triage Assessment and Treatment (ETAT) Module

National Newborn Health Program (NNHP), Ministry of Health and Family Welfare Bangladesh (2019) CC

Over a period of two decades, under-5 mortality rate in Bangladesh has declined by 66% from 133 per 1000 live births in 1993-94 to 45 per 1000 live births in 2017-18. The country reached the MDG-4 goal in the reduction of child mortality on time. However, the comparison of neonatal and under-5 morta... more

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National Action Plan for the Containment and Prevention of Antimicrobial Resistance

Republic of Kenya, Ministry of Health (2021) CC

Antimicrobial resistance (AMR) is a global threat that requires urgent collaborative action within and among countries. As a result of the worldwide reports of the increasing rates of AMR to hospital and community-acquired infections and in the agricultural sector, the Global Action Plan on AMR was... more

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WHO guideline for the treatment of visceral leishmaniasis in HIV co-infected patients in East Africa and South-East Asia

World Health Organzation WHO WHO Neglected Tropical Diseases Department (2022) C_WHO

The leishmaniases are a group of diseases caused by Leishmania spp., which occur in cutaneous, mucocutaneous and visceral forms. They are neglected tropical diseases (NTDs), which disproportionately affect marginalized populations who have limited access to health care. HIV co-infected patients with... more

Guide to eliminate Leprosy as a Public Health Problem. African Edition

World Health Organization WHO (2000) C_WHO

Leprosy will be eliminated when we detect all patients and cure them by using multidrug therapy (MDT). Elimination means bringing the disease burden down to a very low level. This will lead to a reduction in the source of infection, so that leprosy is likely to disappear naturally as it already h... more

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Management of Buruli ulcer–HIV coinfection

World Health Organization WHO (2020) C_WHO

Technical Update Areas of Africa endemic for Buruli ulcer (BU), caused by Mycobacterium ulcerans, also have a high prevalence of human immunodeficiency virus (HIV), with adult prevalence rates between 1% and 5% (Maps). However, there is limited information on the prevalence of BU–HIV coinfection.... more

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Global antimicrobial resistance and use surveillance system (‎GLASS)‎ report: 2022

World Health Organisation (WHO) (2022) C_WHO

The WHO Global Antimicrobial Resistance and Use Surveillance System (GLASS) was launched in 2015 to foster AMR surveillance and inform strategies to contain AMR. The system started with surveillance of AMR in bacteria causing common human infections and has expanded its scope to include surveillance... more

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Pre-referral treatment with rectal artesunate of children with suspected severe malaria: a field guide

World Health Organization WHO (2023) C_WHO

Prompt, effective antimalarial treatment, and supportive care can substantially reduce the rate of mortality from severe malaria. However, many children in malaria-endemic countries do not have access to health facilities or a qualified health care provider and do not receive the necessary care in a... more

Tuberculosis in Brazil: the impact of the COVID-19 pandemic

Fernandes Maia, C.M.; Barbosa Martelli, D. R.; Mendes L. da Silveira, D. M.; et al. Sociedade Brasileira de Pneumologia e Tisiologia (2022) CC

J Bras Pneumol. 2022;48(2):e20220082 The spread of Severe Acute Respiratory Syndrome - Coronavirus 2 (SARS-CoV-2) continues to progress, causing damage in several countries of the world due to its rapid transmissibility and significant mortality rates, despite government measures to contain its tra... more

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Optimized Supportive Care for Ebola Virus Disease
recommended

World Health Organization WHO (2019) C_WHO

Clinical management standard operating procedures. Ebola virus disease (EVD) is a life-threatening multisystem illness associated with fever and gastrointestinal (GI) symptoms that frequently leads to hypovolaemia, metabolic acidosis, hypoglycaemia, and multi-organ failure. The prolonged 2013–201... more

Chagas Disease: From Discovery to a Worldwide Health Problem

Lidani, K.; Andrade, F.; Bavia, L. et al. Frontiers Public Health (2019) CC

Carlos Chagas discovered American trypanosomiasis, also named Chagas disease (CD) in his honor, just over a century ago. He described the clinical aspects of the disease, characterized by its etiological agent (Trypanosoma cruzi) and identified its insect vector. Initially, CD occurred only in Latin... more

Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

WHO guideline on preventive chemotherapy for public health control of strongyloidiasis ﻿ recommended

Optimized Supportive Care for Ebola Virus Disease recommended

WHO guideline on preventive chemotherapy for public health control of strongyloidiasis
recommended

Optimized Supportive Care for Ebola Virus Disease
recommended