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This document was prepared in response to a need to review and potentially update the current recommendations for the antibiotic treatment of both inpatient and outpatient management of severe acute malnutrition (SAM). The current recommendations (Table 1) are based on guidelines published in 2013 i ... more
These guidelines aim to guide all health care providers in Myanmar, accommodating the situation of different settings in the context of progressive decentralization of HIV services. Notable changes from the previous edition include:
• diagnosis of HIV
• update on the initiation of ART
... more
In 2016 CRS leveraged the robust infrastructure of its large, multi-sectoral orphans and vulnerable children (OVC) program in Nigeria by expanding the program's core mandate to include community childhood TB casefinding, with a focus on highly vulnerable children and their caregivers
Background: Evidence based treatment interventions for young people with first-episode psychosis (FEP) and trauma histories is lacking. Although case formulation (CF) has been widely regarded in cognitive behavioural therapy manuals as beneficial, there is limited empirical research examining how cl ... more
The Hand Hygiene Self-Assessment Framework is a systematic tool with which to obtain a situation analysis of hand hygiene promotion and practices within an individual health-care facility.
Q5.SCOPING QUESTION: In individuals with psychotic disorders (including schizophrenia) who require long-term antipsychotic treatment, what is the safety and role of depot antipsychotic medication?

Treating Opioid Addiction in Criminal Justice Settings

National Institute on Drug Abuse (2017) C2
A guide to help you create an Action Plan specific for your health-care facility
This publication is intended for professionals training or practicing in mental health and not for the general public. The opinions expressed are those of the authors and do not necessarily represent the views of the Editor or IACAPAP. This publication seeks to describe the best treatments and pra ... more
Report of the 23rd WHO Expert Committee on the selection and use of essential medicines This executive summary reports the recommendations made by the Expert Committee for the 2021 update of the WHO Model List of Essential Medicines (EML) and the Model List of Essential Medicine for Children (EMLc) ... more
MEDBOX Issue Brief No.2. The main route of transmission of the Sars-CoV-2 virus are small respiratory droplets. Therefore, thoroughly cleaning of hands with either alcohol-based hand rub or soap and water is one of the corner stones of basic protective measures against COVID-19 for everyone. A part ... more

Guidelines for the Management of Tuberculosis in children

Department: Health Republic of South Africa (2013) C2
Health

Providing differentiated delivery to children and adolescents

A. Grimsrud; D.Walker; W. Ameyan; S. Brusamento Unicef; World Health Organization; Pata Pata Pata; IAS (2019) C_WHO
Child Survival Working Group Accessed: 18.10.2019

Annex 3. Dosages of ARV drugs

World Health Organization (2019) C_WHO
Accessed: 19.10.2019
Supplement Article www.jaids.com J Acquir Immune Defic Syndr  Volume 78, Supplement 1, August 15, 2018

A Global Research Agenda for Pediatric HIV

M. Penazzato; C. Irvine; M. Vicari; et al Journal of Acquired Immune Deficiency Syndromes (JAIDS); Ovid (2018) CC
Supplement Article www.jaids.com J Acquir Immune Defic Syndr  Volume 78, Supplement 1, August 15, 2018

Tuberculosis and HIV co-infection in children

E. Venturini; A. Turkova; E. Chiappini; et al. BMC Infectious Diseases; BioMed Central; PubMed.gov (2014) CC
Venturini et al. BMC Infectious Diseases 2014, 14(Suppl 1):S5 http://www.biomedcentral.com/1471-2334/14/S1/S5
Plan Benin used the Integrated Management for Child Illnesses (IMCI) framework in creating the project "Collaborative Approach to Community based Malaria Prevention.” The project targeted 20 pilot villages in the communes of Aplahoué and Djakotomey, with the goal of reducing maternal and infant m ... more

Global Fund Financing of HIV - WHO/UNAIDs Annual Meeting with Manufacturers and Stakeholders

The Global Fund; World Health Organization; et al. (2016) C_WHO
8-11 March 2016
WHO Annual Meeting with Pharmaceutical Companies and Stakeholders 08 March 2016, Geneva 2015-06-03 - Board presentation - v32.pptx
Research Article PLOS ONE | DOI:10.1371/journal.pone.0164619 October 13, 2016
Accessed: 26.11.2019
HIV i-Base July 2018
Médecins sans Frontières access campaign Issue Brief Accessed: 28.11.2019
Technical Update HIV Treatment July 2017

Introduction to ART

i-base (2018) C2
May 2018 HIV i-Base ISSN 1475-2077 www.i-Base.info Watch for out-of-date information First questions You and your doctor Resistance and adherence Treatment choices
www.i-Base.info Accessed: 28.11.2019

Guidelines for the managment of epilepsy in India

Indian Epilepsy Society Ministry of Health & Family Welfare, India (2007) C1
30.03.2015
WHO recommends member states provide universal access to public hand hygiene stations and making their use obligatory on entering and leaving any public or private commercial building and any public transport facility. It is also recommended that healthcare facilities improve access to and practice ... more
Orientations provisoires 1er avril 2020 Les États Membres doivent améliorer les pratiques d’hygiène des mains de manière ambitieuse afin d’aider à prévenir la transmission du virus de la COVID-19 : 1. en fournissant un accès universel à des postes publics d’hygiène des mains et ... more
Current evidence indicates that the COVID-19 virus is transmitted through respiratory droplets or contact. Contact transmission occurs when contaminated hands touch the mucosa of the mouth, nose, or eyes; the virus can also be transferred from one surface to another by contaminated hands, which fac ... more
In December 2019 a novel coronavirus (2019-nCoV) was identified as the causative agent of a severe acute respiratory illness among people exposed in a seafood market in Wuhan, China; • Human-to-human transmission has been documented, including in healthcare workers, and aerosol-generating procedur ... more
L’ hygiène des mains est la mesure la plus efficace pour réduire la propagation des infections dans le cadre de stratégies multimodales, y compris l’accès à des fournitures appropriées. Les présentes orientations concernent donc tous les pays ... more
This article is part four in a series of explainers on vaccine development and distribution Available in different languages
This article is part two in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. This article focuses on the ingredients in a vaccine and the three clinical trial phases. Part three outlines the nex ... more
Preferred product characteristics” (PPCs) are key tools to incentivize and guide the development of urgently needed health products. The PPC published here describes the characteristics of new types of insecticide-treated nets (ITNs) to control malaria transmission in areas with insecticide-resist ... more
August 2020. Essential diagnostic products areconsidered an integral part of UHC, they are an indispensable element for delivery ofservices andare also a requirement for qualitycare. Despite this realization, a review of the UHC pilot in September 2019 es ... more
August 2020. In December 2018, the President launched the UHC pilot covering four strategically selected counties-Isiolo, Kisumu, Machakos and Nyeri. It isplanned that by the year 2022, all persons in Kenya will be able to use the essential services they need for their health ... more
Two test methods on dexamethasone tablets and injections
23 March 2021 The meeting addressed the last key area, that is, determining the best method or combination of diagnostic methods for a control programme for S. stercoralis infections in humans. Dr Montresor’s presentation highlighted that while there is currently no “gold standard” for the ... more
Nurses play a critical role in patient care, detecting potential problems, and advocating for a culture of safety. NSO and our insurance carrier partner, CNA, designed this self-assessment checklist based on significant topics from our Nurse Claim Report to help nurses enhance patient safety and min ... more
7 August 2021
Cet article fait partie d’une série d’explications à propos de la mise au point et de la distribution des vaccins. Available in English, French, Spanish, Arabic, Chinese and Russian

Extemporaneous Dosage Forms: Oral Liquids

Nguyen, T. The Australian College of Pharmacy (2019) CC
After completing this activity, pharmacists should be able to: 1. List populations for which the compounding of an oral liquid may be necessary 2. Outline necessary considerations that should be made by the pharmacist to ensure product stability 3. Describe methods used in the compounding of liqu ... more
Revision Bulletin ESPNF
This collection of posters are intended for health care workers, biomedical engineers and staff of health facilities in charge of caring, cleaning, decontaminating and sterilizing respiratory medical equipment in hospitals and health facilities. They include checklists to ensure the optimal infectio ... more
European Journal of Biomedical and Pharmaceutical Sciences, vol.3 (2016) 1, 192-206 This review shows that if all sub areas of pharmaceutical waste management can efficiently work back to back environmental pollution and dangers to human health can reduce significantly.
Bilevel or two-level Positive Airway Pressure (BiPAP). Continuous Positive Airway Pressure (CPAP) During non-invasive ventilation and between patients Always read and follow the instructions and recommendations of the manufacturer`s manual Consumables associated with oxygen delivery are genera ... more
During ventilation and between patients Always read and follow the instructions and recommendations of the manufacturer`s manual Consumables associated with oxygen delivery are generally intended as single use devices, and should be treated as infectious material and disposed of accordingly. Dispo ... more
During monitoring and between patients Always read and follow the instructions and recommendations of the manufacturer`s manual The device must be cleaned and disinfected after each individual use and, at minimum weekly, prior to use on another patient.
During non-invasive ventilation and between patients Always read and follow the instructions and recommendations of the manufacturer`s manual Consumables associated with oxygen delivery are generally intended as single use devices, should be treated as infectious material and disposed of according ... more
Consumables associated with oxygen delivery are generally intended as single use devices. They should be treated as infectious1 material and disposed of accordingly. Disposal of patient interface, tubing, water bag and water chamber, for example, should be done as per facility standard operating pro ... more
Lecture 9 Developing countries regional anesthesia lecture series
The world agreed to achieve 17 Sustainable Development Goals by 2030. Nine planetary boundaries set an upper limit to Earth system impacts of human activity in the long run. Conventional efforts to achieve the 14 socio-economic goals will raise pressure on planetary boundaries, moving the world away ... more
N Engl J Med 2022; 386:911-922, DOI: 10.1056/NEJMoa2104535 Four months of antituberculosis treatment was noninferior to 6 months of treatment in children with drug-susceptible, nonsevere, smear-negative tuberculosis (SHINE Study)
11 April 2022
The Committee discussed the implications for preparedness for smallpox-like events reflected by the ongoing COVID-19 pandemic. The Committee noted how quickly diagnostics and vaccines could be developed and deployed when resources and political will were abundant. This rapidity was also due to the f ... more
During the COVID-19 health crisis, community pharmacists had an enhanced role in supporting health-care systems that were overburdened by managing seriously ill patients. This study was undertaken to determine the patterns of community supply of antiviral and antibacterial agents from community phar ... more
Minimizing risk of developing antibiotic resistance and aquatic ecotoxicity in the environment resulting from the manufacturing of human antibiotic. The Standard, facilitated by BSI Standards Limited (BSI), provides clear guidance to manufacturers in the global antibiotic supply chain to ensure t ... more
The new treatment recommendations that extend the 2018 treat all recommendation for adults with chronic HCV infection to include adolescents and children down to 3 years, and to align the existing recommended pangenotypic direct-acting antiviral (DAA) regimens (SOF/DCV, SOF/VEL and G/P) for adults, ... more
Cryptococcal disease, particularly cryptococcal meningitis is a significant cause of morbidity and mortality among people living with HIV with advanced HIV disease. It is estimated that it is responsible for nearly 19% of AIDS-related mortality, second only to tuberculosis. Rapid screening, diagnosi ... more

HIV prevention 2025 road map

UNAIDS World Health Organization WHO (2022) C_WHO
Getting on track to end AIDS as a public health threat by 2030. This new Road Map charts a way forward for country-level actions to achieve an ambitious set of HIV prevention targets by 2025. Those targets emerged from the 2021 Political Declaration on HIV and AIDS, which the United Nations General ... more

La prévention du VIH pour 2025 — Feuille de route

UNAIDS World Health Organization WHO (2022) C_WHO
Cette nouvelle feuille de route trace la voie à suivre pour les actions à mener au niveau national afin d’atteindre un ensemble ambitieux d’objectifs de prévention du VIH d’ici 2025. Ces objectifs sont issus de la Déclaration politique 2021 sur le VIH et le sida, que l’Assemblée génér ... more
Front Chem. 2021; 9: 622286. Published online 2021 Mar 12. doi: 10.3389/fchem.2021.622286
Over 6 million people worldwide are infected with Trypanosoma cruzi, the protozoan that causes Chagas disease (CD). T. cruzi is transmitted by triatomine insects, congenitally, through uncontrolled blood donations and organ transplants, and via consumption of food or drink contaminated by triatomi ... more
The WHO Pharmaceuticals Newsletter provides you with the latest information on the safety of medicinal products and regulatory actions taken by authorities around the world. In addition, this edition includes summary and recommendations from the virtual meeting of the members of the WHO Programme f ... more
Smallpox eradication was certified in 1980. Mpox has been endemic in Central and West African countries since it was first detected in 1958 . It is a zoonosis; cases are often found close to tropical rainforests where various animals carry the orthopoxvirus that causes the disease. In endemic countr ... more
The Malawian government recently introduced cost-covering consultation fees for self-referral patients in tertiary public hospitals. Previously, patients received medicines free of charge in government-owned health facilities, but must pay elsewhere. Before the government implements a payment policy ... more
Asthma can be a serious disease, but if you understand the disease and take the right medication to control it, you should have no problems or symptoms due to your asthma, even when you are pregnant. To be free from asthma attacks, you should also check your lung function and use an action plan ... more
Bonchial asthma is the most common chronic respiratory disease in the world. In Kenya, it has been estimated that about 7.5% of the Kenyan population, nearly 4 million people, are currently living with asthma. Many cases tend to be underdiagnosed and undertreated which leads to high levels of morbid ... more
This document defines the framework for Malawi’s National HIV Programs. Considering public health benefits and risks, as well as funding and resource implications, deviations from these guidelines are not supported by the Ministry of Health.
The Practical Approach to Emergencies in the Pregnant Mother, Newborn infant and Child. Provder Manual
A manual for physicians and other senior health workers. This fourth revision of the manual reflects recent clinical experience and research findings in diarrhoea case management. Compared to earlier versions, it includes revised guidelines on the management of children with acute diarrhoea using th ... more
Guide pratique d’utilisation à l'usage des médecins, pharmaciens, infirmiers et auxiliaires de santé.

Desk-guide for diagnosis and management of TB in children - Africa Edition

Graham, S.M.et al. International Union Against Tuberculosis and Lung Disease (2016) C1
3rd edition
• provide scientific information on the safety, efficacy, and quality control/ quality assurance of widely used medicinal plants, in order to facilitate their appropriate use in Member States; • provide models to assist Member States in developing their own mono- graphs or formularies for these ... more
Practical guide intended for physicians, pharmacists, nurses and medical auxiliaries. This guide is not a dictionary of pharmacological agents. It is a practical manual intended for health professionals, physicians, pharmacists, nurses and health auxiliaries invoved in curative care and drug managem ... more
Interagency Guidelines - This revised Interagency List of Essential Medicines for Reproductive Health presents the current international consensus on rational selection of essential reproductive health medicines. The list is intended to support decisions regarding the production, quality assurance ... more
WHO Model Formulary for children based on the Second Model List of Essential Medicines for Children 2009. In 2007, the World Health Assembly passed a Resolution titled ‘Better Medicines for Children’. This resolution recognized the need for research and development into medicines for children, ... more
The 7th edition of the Orange Guide provides practical guidance to health workers on the front line of TB control. It includes sections on HIV, MDR-TB and a review of the recommended treatment regimens
4th edition. This is fourth edition of Treatment of tuberculosis: guidelines, adhering fully to the new WHO process for evidence-based guidelines. Several important recommendations are being promoted in this new edition
This Handbook, an updated edition of the Management of Severe Malaria, provides new and revised practical guidance on the diagnosis and management of severe malaria.
1.HIV infections – drug therapy. 2.Anti-HIV agents – adverse effects. 3.Anti-retroviral agents. 4.Benzoxazines – adverse effects. 5.Pregnancy. 6.Disease transmission, Vertical - prevention and control. 7.Treatment outcome. I.World Health Organization