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Desk-guide for diagnosis and management of TB in children - Africa Edition

Graham, S.M.et al. International Union Against Tuberculosis and Lung Disease (2016) C1
3rd edition
International Journal of Infectious Diseases 80 (2019) 10–15 journal homepage: www.elsevier.com/locate/ijid
Following review of the latest evidence, WHO recommends that TB-LAMP can be used as a replacement for microscopy for the diagnosis of pulmonary TB in adults with signs and symptoms of ... more
Joining efforts to control two trelated global epidemics.
BMJ,Dodd PJ, et al. Thorax 2017;72:559–575. doi:10.1136/thoraxjnl-2016-209421
Integrated Management of Adolescent and Adult Illness (IMAI) July 2008
2nd edition
The Compendium of data and evidence-related tools for use in TB planning and programming was developed as a companion document to the People-centred framework for tuberculosis programme planning and prioritization – user guide, pu ... more
In the framework of the United Nations Sustainable Development Goals Issue-based Coalition on Health and Well-being for All at All Ages in Europe and Central Asia
A compendium of TB REACH case studies, lessons learned and a monitoring and evaluation framework. Accessed November 2017.

People living with HIV

M. Smelyanskaya, J. Duncan; C. Daniels, et al. Stop TB Partnership; The Focus Group Consulting (2017) C1
Key populations brief Accessed November 2017
Annex 1: Measuring progress towards targets Annex 2: Modelling the impact of the 90-(90)-90 strategy Annex 3: Investment packages by country setting Annex 4: Country strategies Annex 5: Strategic frameworks for research and development for new tools Annex 6 : Estimating the cost of the 90-(90)- ... more
TB policies in 24 Countries A survey of prevention, testing and treatment policies and practices Лечение туберкулеза в 24 странах Исследование диагностической и клинической пра ... more
Towards a world free of tuberculosis
Evidence from two pilot projects in India.
For Children and their Families October 2015
TB policies in 29 Countries A survey of prevention, testing and treatment policies and practices
The present Consolidated guidelines include a comprehensive set of WHO recommendations for the treatment and care of DR-TB, derived from these WHO guidelines documents. The consolidated guidelines include policy recommendations on treatment regimens ... more
6 de diciembre del 2010
Interim policy guidance.
Исследование этого года основано на предыдущем отчете. В нем отслеживается утверждение последних стратегий, руководств и методов в пяти сферах: диагностика и иссл ... more
Цель этого документа – повысить уровень осознания актуальности приоритетных направлений научных исследований по проблеме ТБ/ВИЧ (то есть по тем направлениям, кот ... more
В основе настоящих руководящих принципов лежит структура организации мероприятий в соответствии с тремя задачами: • создание и укрепление механизмов комплексно ... more

Training Package on XPERT MTB/RIF

USAID; WHO; FIND; et al. global laboratory initiative (2017) C_WHO
The modules (1-12) are based on materials originally developed by FIND, KNCV and Cepheid, and are in PowerPoint format for country customization. Depending on the audience, modules may be selected and adapted according to need (e.g. basic users, supervisors, clinicians). Topics covered include: Over ... more
The practical guidance in the operational handbook aims to inform the development or revision of national policies and related implementation guidance on the management of TB in children and adolescents under programmatic circumstances and at differ ... more

Tuberculosis - A manual for medical students

N. Ait-Khaled, D. Enarson World Health Organization; International Union Against Tuberculosis and Lung Disease (1999) C_WHO
WHO/CDS/TB/99.272
HIV/TB workplace policy and Implementation Strategy
The update of the ESTC was conducted as a joint endeavour with ERS, consulting experts from international societies and organisations, national TB programmes, civil society and affected communities. The second edition of the ESTC includes 21 standar ... more
Rev Panam Salud Publica. 2021;45:e74. Some characteristics of patients and healthcare providers influence treatment success in MDR-TB cases. Physicians’ and nurses’ knowledge about MDR-TB must ... more
This rapid communication outlines the main outcomes of a WHO convened Guideline Development Group (GDG) meeting, held in May-June 2021 on the topic of the management of TB in children and adolescents. The rapid communication aims to inform staff fr ... more
A review of available evidence (2016). 28-29 June 2016; Geneva, Switzerland The END TB strategy.
WHO/HTM/TB/2012.9
Improving the management of childhood tuberculosis within national tuberculosis programmes: research priorities based on a literature review WHO/HTM/TB/2007.381, 07.02
The new WHO recommendations for the treatment of isoniazid-resistant, rifampicin-susceptible TB are based upon a review of evidence from patients treated with such regimens by a Guideline Development Group in conformity with WHO requirements for evi ... more
2nd edition. T The Compendium has been developed as a clear and concise instrument to facilitate the understanding and planning of delivery of high-quality care for everybody affected by TB. It incorporates all recent policy guidance from WHO; foll ... more
Myanmar is one of the world’s 22 high tuberculosis (TB) burden countries, and supporting TB control in Myanmar is a global priority. This report reflects the findings, discussions, conclusions and ... more
National Tuberculosis Programme and Senior Paediatricians
This guideline was first developed in 2007 but further updated in 2012 and 2016 to ensure the use of the latest evidence-based international recommendations on childhood TB. The guidelin ... more
TB remains one of the world’s deadliest infectious diseases, second only to COVID-19, and drug-resistant TB strains are still a major concern. In the fight against ... more
The review’s objectives are to review progress in TB control with emphasis on DOTS strategy implementation, summarize the experience, lessons learnt and methods of work and to make recommendations for international donors, technical agencies and t ... more
13 May 2021 To avoid a reversal of progress from the adverse impacts of the COVID-19 pandemic, new knowledge and lessons from successful programmatic innovations are urgently needed to improve TB prevention and care. Experience can provide evidence ... more
The consolidated guidelines are complemented by an operational handbook which is designed to assist with implementation of the WHO recommendations by Member States, technical partners and others who are involved in the management of patients with DR-TB ... more
6 July 2021. Three new nucleic acid amplification test (NAAT) classes are endorsed by WHO and included. The latest operational handbook includes the new classes recommended by WHO. It aims at facilitating the implementation of the WHO recommendations by the Member States, technical partners, and ot ... more
The Global Strategy for Tuberculosis Research and Innovation will support the efforts of governments and other stakeholders to accelerate TB research and innovation, and improve equitable access to the benefits of research. Availabl in Arabic, Chin ... more
Meeting Report 27-29 October 2020 The overall goal of the meeting was to discuss recent changes in treatment regimens and diagnostics for drug-resistant TB and to determine how these impact on the definition of XDR- ... more
The Updated guidelines on Management of tuberculosis in children and adolescents include new recommendations that cover diagnostic approaches for TB, shorter treatment for children with non-severe drug-susceptible ... more
The overall objective of this implementation plan is to define the strategy for implementation of the Xpert MTB/RIF test for rapid detection of TB and rifampicin (RIF) resistance in Tanzania, within the context of the National Tuberculosis and Lepro ... more
Zoonotic tuberculosis (TB) is a form of TB in people predominantly caused by the bacterial species, Mycobacterium bovis, which belongs to the M. tuberculosis complex. The implications of z ... more
Training for staff working at DR-TB management centres. Training modules
Outstanding child and adolescent TB priorities include the need to: find the missing children with active TB and link them to TB care; prevent ... more
This report has been developed, based on data provided by the TB & ORD surveillance system from across Rwanda. It provides a comprehensive picture of the occurrence and management of TB & ORD and Le ... more
Tuberculosis continues to represent a severe public health problem in the Region of the Americas, even more so in the case of indigenous peoples, whose TB incidence is much higher than that of the general population. To achieve tuberculosis control ... more
These updates include shorter novel 6-month all-oral regimens for the treatment of multidrug- and rifampicin-resistant TB (MDR/RR-TB), with or without additional resistance to fluoroquinolones (pre- ... more
The roadmap describes the actions needed to achieve the three development goals for TB vaccines set by the WHO: 1. A safe, effective and affordable TB vaccine for adolescents and adults. 2. An ... more
The Practical manual on laboratory strengthening, 2022 update provides practical guidance on implementation of WHO recommendations and best practices for TB laboratory strengthening. It is an updated version of the GLI Practical Guide to Laboratory ... more
This guidance is intended for use in developing standalone TB strategic plans, or TB interventions as part of multidisease or health sector plans. It describes key considerations and steps for strat ... more
Version 1.0, 2014-11-21 Introduction: This document lists TB indicators that can be derived from the recording and reporting tools defined in Definitions and reporting framework for tuberculosis – 2013 revision (WHO/HTM/ ... more
The goal of this addendum is to help management and staff 
minimize the risk of TB transmission at facilities in resource limited settings in which a.) HIV-infected persons receive diagnosis, care, treatment, 
and/or support, and b.) there is a ... more
2nd edition. Like the original, this second edition of the guidance aims to inform the revision of existing national guidelines and standards for managing Tuberculosis (TB), many of which include guidance on children. It includes recommendations, b ... more
This report presents an overview of the transition process in Azerbaijan, some sustainability aspects and challenges stemming from donor withdrawal from TB-related activities, along with recommendations on how to overcome transition-related difficu ... more
Este documento presenta modelos de algoritmos que permiten investigar por métodos bacteriológicos a los pacientes para el diagnóstico de tuberculosis (TB), TB asociada al Virus de Inmunodeficienc ... more
This publication is an updated version of the Management of Tuberculosis and HIV Coinfection clinical protocol released in 2007 by the WHO Regional Office for Europe. It is intended for all health care workers involved in preventing, diagnosing, treating and caring for people living with ... more
The manual is written for clinicians working at the district hospital (first-level referral care) who diagnose and manage sick adolescents and adults in resource constrained settings. It aims to support clinical reasoning, and to provide an effective clinical approach and protocols for the managemen ... more
We systematically reviewed Medline as well as the references of published review articles for relevant studies of adherence to multidrug treatment of both drug-susceptible and drug-resistant TB through February 3, 2018. We included randomized contro ... more
Chapter 105
This Tuberculosis guide has been developed jointly by Médecins Sans Frontières and Partners In Health. It aims at providing useful information to the clinicians and health staff for the comprehensive management of tuberculosis. Forms of susceptible and resistant tuberculosis, tuberculosis in child ... more
Sixth edition 2007
180 Biomédica 2018;38:180-8
4th edition. This is fourth edition of Treatment of tuberculosis: guidelines, adhering fully to the new WHO process for evidence-based guidelines. Several important recommendations are being promoted in this new edition
2nd edition
Summary of current WHO recommendations and guidance on programmatic approaches
6 July 2021. The “WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection 2021 update” is the latest document replacing the one issued in 2020. Three new nucleic acid amplification test (NAAT) classes are endorsed by WHO and included in the ... more
Interim policy guidance
Sixth Edition
This Tuberculosis guide has been developed jointly by Médecins Sans Frontières and Partners In Health. It aims at providing useful information to the clinicians and health staff for the comprehensive management of tuberculosis. Forms of susceptible and resistant tuberculosis, tuberculosis in child ... more
National Tuberclosis and Leprosy Programme (NTLP)
3rd edition
Tropical Medicine and International Health volume 21 no 1 pp 101-107 january 2016
UGANDA NATIONAL TUBERCULOSIS AND LEPROSY CONTROL PROGRAMME
Guidelines for treatment of drug-susceptible tuberculosis and patient care Update 2017

Drug-Resistant tuberculosis

E.G. Brown Jr, D.S. Dooley, K. Smith Curry International Tuberculosis Center, State of California, California Health & Human Service Agency, Department of Public Health (2016) C1
A survival guide for clinicans. 3rd edition.
Policy and Manual
Version: 24 April 2018