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This algorithm is addressed to laboratories with established capacity(molecular, antigenic and/orserological) to detect dengue (DENV), Zika (ZIKV), and chikungunya(CHIKV) as part of the differential diagnosis for arborviruses. A BSL2 containment level is required to handle suspected samples.
WHO Factsheet. 14 March 2016
Bulletin of the World Health Organization; http://dx.doi.org/10.2471/BLT.16.176677

Philippines: Leptospirosis Guidelines

Manolito L. Chua, Marissa M. Alejandria Philippine Society for Microbiology and Infectious Diseases (2010) C1
Information leaflets can be downloaded free of charge from http://www.lgl.bayern.de/gesundheit/infektionsschutz/asylbewerber_gesundheit/index.htm under the section "Asylbewerber und Gesundheit". Also available in following language versions: Arabic, Bulgarian, German, French, Greek, Italian, Croati ... more
Interim Technical Note
PLoS Pathogens | www.plospathogens.org 1 February 2012 | Volume 8 | Issue 2 | e100246
BMC Infectious Diseases 2012, 12:352/1471-2334/12/352
This is an updated introductory two-page document that defines AIDS vaccines and reviews key developments in the field.
The five hepatitis viruses have different epidemiological profiles, and their impact, duration, and transmission route also vary. The most common transmission routes contributing to the spread of hepatitis are exposure to infected blood via blood transfusion or unsafe injection practices, consumptio ... more

Introduction to Ebola disease: Managing infectious hazards

Formenty, Pierre World Health Organization (WHO) (2018) C_WHO
Emergency WASH in Health Facilities in Conflict Affected Locations 756 health workers trained on disease surveillance and outbreak response. Around 142 health workers trained on integrated health (WASH and Nutrition) response. 405 health facilities are equipped with functional incinerators. Qual ... more
Enfrentando la enfermedad de Alzheimer en los países en desarrollo. Rev Neuropsiquiatr 80 (2), 2017 (P. 105-110) Recibido: 03/02/2017 Aceptado: 12/06/2017

Factsheet about tick-borne encephalitis (TBE)

European Centre for Disease Prevention and Control (2019) C2
Accessed: 11.03.2019
Int J Health Geogr. 2002; 1: 5. Published online 2002 Dec 20. doi: 10.1186/1476-072X-1-5 PMCID: PMC149400 PMID: 12537588
Fact Sheet, May 2018. Nipah virus (NiV) is a zoonotic virus (it is transmitted from animals to humans) and can also be transmitted through contaminated food or directly between people. In infected people, it causes a range of illnesses from asymptomatic (subclinical) infection to acute respiratory ... more
The aims of these guidelines are to provide guidance to health-care providers (i.e. the end-users of these guidelines: physicians, nurses, pharmacists and caregivers) on the adequate relief of pain associated with cancer. They also assist policy-makers, programme managers and public health personnel ... more

Pathophysiology of the human immunodeficiency virus

N. R. Calles; D. Evans; D.L. Terlonge Baylor International Pediatric AIDS Initiative (BIPAI) (2019) C2
Accessed: 03.09.2019

Лечение и уход в связи с ВИЧ/СПИДом в Беларуси

J. D. Lundgren D. Raben; И. Ерамова, В. Ильенкова, Всемирная организация здравоохранения (World Health Organization Europe); Centre for Health & Infectious Disease Research (2014) C_WHO
Отчет оценочной миссии Январь 2014 г
Analytical report
Product:BDFACSCountTM InstrumentSystemwithFACSCountTM ControlKitandBD FACSCountTM CD4ReagentKit(AbsoluteandPercentageCD4+Counts) Number: PQDx 0133-045-00 0133-045-00 WHO PQDx PR June/2016, version 2.0
PQDx 0197-045-00 WHO PQDx PR March /2016, version 2.0

Factors associated with hepatitis C seropositivity in people living with HIV

V. M. Kuehlkamp; I. J. C. Schneider; M. F. Biudes; et al. PAHO (Pan American Health Organization; World Health Organization); Iris (Institutional Repository); Rev Panam Salud Publica (2014) C2
Investigación original / Original research Rev Panam Salud Publica 35(1), 2014
Rutstein SE et al. Journal of the International AIDS Society 2017, 20:21579 http://www.jiasociety.org/index.php/jias/article/view/21579 | http://dx.doi.org/10.7448/IAS.20.1.21579
Policy Brief. WHO recommends that pregnant women receive testing for HIV, syphilis and hepatitis B (HBSAg) at least once during pregnancy, preferably in the first trimester. Dual HIV/syphilis rapid diagnostic tests (RDTs) can be used as the first test for pregnant women as part of antenatal care ( ... more

HIV Pipeline 2018

i-base (2018) C2
htb supplement: 2018 Vol 19:(1) New drugs in development July 2018 www.i-Base.info
Standard Treatment Guidelines
The World Health Organization (WHO) has recommended a universal antiretroviral therapy (ART) for all HIVinfected children before the age of two since 2010, but this implies an early identification of these infants. We described the Prevention of Mother-to-Child HIV Transmission (PMTCT) cascade, the ... more
Accessed: 27.03.2020
Interium guidance, 25 June 2021Timely and accurate diagnostic testing is an essential tool in preventing and controlling the spread of COVID-19. This document describes recommendations for national testing strategies and the use of PCR and rapid antigen tests in different transmission scenarios of t ... more
The following protocol has been designed to investigate the extent of infection, as determined by seropositivity in the general population, in any country in which COVID-19 virus infection has been reported. Each country may need to tailor some aspects of this protocol to align with public health, l ... more
Научная справка 8 апреля 2020 г. В ответ на растущую пандемию COVID-19 и нехватку ресурсов и реагентов для молекулярного тестирования, многие производители диагностич ... more
Nota científica 24 de abril de 2020 El desarrollo de inmunidad a un patógeno por infección natural es un proceso de varias etapas que suele producirse a lo largo de una o dos semanas. El organismo responde a una infección vírica de forma inmediata a través de una respuesta innata no específ ... more
Document d’information scientifique 24 avril 2020 Le développement d’une immunité face à un agent pathogène à la suite d’une infection naturelle comporte plusieurs étapes et prend généralement une à deux semaines. Une infection virale entraîne immédiatement une réponse immunit ... more
The speed of developing diagnostics for SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19), has been quite remarkable. Diagnostics have focused on nucleic acid amplification testing (NAAT) to identify infected individuals in acute-phase disease for timely implementation of mitiga ... more
Breastfeeding is the cornerstone of infant and young child survival, nutrition and development and maternal health. The World Health Organization recommends exclusive breastfeeding for the first 6 months of life, followed by continued breastfeeding with appropriate complementary foods for up to 2 ye ... more
The number of confirmed COVID-19 cases detected and reported in each country is influenced by many factors including limited access and/or utilization of healthcare and COVID-19 testing, limited surveillance, lack of knowledge amongst the population about when to seek testing, an asymptomatic pres ... more
Available in Arabic, Chinese, English, French, Portuguese and Spanish https://apps.who.int/iris/handle/10665/334254
This module is part of the WHO series The Immunological Basis for Immunization, which was initially developed in 1993 as a set of eight modules, comprising one module on general immunology and seven modules each devoted to one of the vaccines recommended for the Expanded Programme on Immunization, i ... more
16 Dec. 2020 This document provides guidance to Ministries of Health (MOHs), laboratory personnel and implementing partners in African Union Member States on the application of rapid antigen tests to COVID-19 testing. The guidance serves as reference for policymakers, laboratory leads, implementing ... more
These WHO interim recommendations on the use of the Pfizer – BioNTech BNT162b2 vaccine against Covid-19 were developed on the basis of advice issued by the Strategic Advisory Group of Experts on Immunization (SAGE) and the evidence summary included in the background document referenced below. fir ... more
The objectives of pertussis surveillance are to:hmonitor disease burden and the impact of the pertussis vaccination programme, with a special focus on understanding the morbidity and mortality in children < 5 years of agehgenerate data to inform vaccine schedule and delivery strategy decisions to optimize the impact of ... more
These WHO interim recommendations on the use of the Astra Zeneca – Oxford University AZD1222 vaccine against Covid-19 were developed on the basis of advice issued by the Strategic Advisory Group of Experts on Immunization (SAGE) and the evidence summary included in the background document referenc ... more
February 2021. Improving our response to the ongoing COVID-19 pandemic in Africa requires regularly updated information, constant innovation, and considerable support towards research and development (R&D) for priorities that respond to the African realities. Shaping the research agenda and stimula ... more
1 March 2021 This article is part of a series of explainers on vaccine development and distribution. Learn more about vaccines – from how they work and how they’re made to ensuring safety and equitable access – in WHO’s Vaccines Explained series.
An overview of COVID-19 Vaccine AstraZeneca and why it is authorised in the EU. Available in 22 languages 18 Febr. 2021
21 августа 2020 г. В этом документе представлены рекомендации для лиц, принимающих решения, работников общественного здравоохранения и специалистов в области педиа ... more
21 August 2020 This guidance provides specific considerations for the use of non-medical masks, also known as fabric masks, by children as a means for source control in the context of the current COVID-19 pandemic. It also advises on the use of medical masks for children under certain conditions.
This document provides interim guidance on the prevention, identification and management of health worker infection in the context of COVID-19. It is intended for occupational health departments, infection prevention and control departments or focal points, health facility administrators and public ... more
The guide explains how vaccines work and answers your common questions as well as providing up-to-date information on the current approved COVID-19 vaccinations in the UK. This guide was written in January 2021 and updated in March 2021 and is accurate at the time of publishing. Information will b ... more
6 June 2022 These WHO interim recommendations on the use of the Janssen Ad26.COV2.S (COVID-19) vaccine were developed on the basis of advice issued by the Strategic Advisory Group of Experts on Immunization (SAGE) and the evidence summary included in the background document referenced below. Th ... more
26 March 2021 Slideset updated regularly to include the latest data on the evolution and duration of COVID-19 symptoms and prevalence and duration of natural immunity.
These are standing orders for eligible nurses and healthcare professionals to administer the Moderna COVID-19 vaccine to persons 18 years of age and older
BMJ 2020; 370 doi: https://doi.org/10.1136/bmj.m3379 Rapid Recommendation and visual graph. This is the fifth version (update 4) of the living guideline (BMJ 2020;370:m3379). When citing this article, please consider adding the update number and date of access for clarity. The publication of the RE ... more
This quick guide offers basic information about COVID-19, the Sinovac-CoronaVac COVID-19 vaccine and what to expect following vaccination: ...
interim guidance, 19 July 2021 (arabic version)
Issue Brief no. 16. 20 Sept 2021. Many studies have shown the effectiveness of vaccination against COVID-19 and that it protects against severe illness. A high vaccination rate is needed to combat the pandemic worldwide. Due to misinformation and myths, there is still a great hesitancy to vaccina ... more
Internews and Maharat collected and analyzed 433 rumors about COVID-19 circulating on social media between January 5, 2021and January 31, 2021. This bulletin highlights community perceptions and criticisms about different topics
These WHO interim recommendations for use of the BBV152 COVAXIN vaccine were developed on the basis of advice issued by the Strategic Advisory Group of Experts on Immunization (SAGE) and the evidence summary included in the background document and annexes referenced below. This document has been ... more
These WHO interim recommendations for use of the COVID-19 vaccine BIBP produced by Sinopharm were developed on the basis of advice issued by the Strategic Advisory Group of Experts on Immunization (SAGE) and the evidence summary included in the background document and annexes referenced below. Th ... more
Illustrated by A. Scheffler and contribution by G. Medley
WHO is working with Viamo, a global social enterprise improving lives via mobile, to provide WHO’s COVID-19 information, including vaccines, to the hardest to reach populations, in their languages, through the mobile phones they own. This includes people with simple phones (feature phones) or with ... more
Natural immunity against COVID-19 Scientific report 10 May 2021
17 Febr. 2022. As part of the “Strategy to Achieve Global COVID-19 Vaccination by mid-2022”, global targets of 40% population coverage by end of 2021 and 70% coverage by June 2022 have been set by the World Health Organization (WHO), to successfully prevent severe illness and deaths, minimize so ... more
Hendra virus (HeV) continues to pose a serious public health concern as spillover events occur sporadically. Terminally ill horses can exhibit a range of clinical signs including frothy nasal discharge, ataxia or forebrain signs. Early signs, if detected, can include depression, inappetence, colic o ... more
The Committee discussed the implications for preparedness for smallpox-like events reflected by the ongoing COVID-19 pandemic. The Committee noted how quickly diagnostics and vaccines could be developed and deployed when resources and political will were abundant. This rapidity was also due to the f ... more
first issued 18 August 2022
Der BAGSO-Ratgeber informiert kompakt und verständlich zu Impfungen für Erwachsene ab 60 Jahren. Er gibt Antworten auf zwölf häufig gestellte Fragen, u.a. für wen welche Impfungen besonders wichtig sind, wo man sich beraten lassen kann und ob die Kosten von der Krankenkasse übernommen werden. ... more
Testing Guidance and Interpretation of Results for Healthcare providers
Testing Guidance and Interpretation of Results for Healthcare Providers Dengue and Zika Virus
To support its R&D activities on Chagas disease, DNDi launched the Chagas Clinical Research Platform (CCRP). The platform brings together partners, experts, and stakeholders to provide support for evaluation and development of new treatments for Chagas disease. The patient-centred platform aims to f ... more
Information on Chikungunya Fever
The development of this target product profile (TPP) was led by the WHO Department of Control of Neglected Tropical Diseases (NTD) following standard WHO guidance for TPP development. In order to identify and prioritize diagnostic needs, a WHO NTD Diagnostics Technical Advisory Group (DTAG) was form ... more
Localized cutaneous leishmaniasis and its evolving forms (diffuse cutaneous leishmaniasis, mucosal leishmaniasis and cutaneous leishmaniasis recidivans), together with the sequela of visceral leishmaniasis (post-kala-azar dermal leishmaniasis), account for about one million cases of dermal leishmani ... more
UNICEF, WHO Whole of Syria Nutrition, Cluster, the Global Nutrition Cluster, the IFE Core Group, and partners call for ALL involved in the response to the earthquakes in Syria to protect, promote, and support the feeding and care of infants and young children, their caregivers, especially pregnant, ... more
• Leptospirosis is a disease that is caused by spirochete bacteria in the genus Leptospira. There are 10 pathogenic species, and more than 250 pathogenic serovars. • While leptospirosis occurs worldwide, it is more common in tropical or sub-tropical climates.
Rabies has an enormous impact on both agriculture and conservation biology, but its greatest burden is undeniably on public health. As such, routine methods for rapid risk assessment after human exposures to rabies as well as applications for laboratory-based surveillance, production of biologicals ... more