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Cholera is an acute diarrhoeal disease caused by the ingestion of food or water contaminated with the bacterium V.
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(2015)
C2
The international community sits at the tipping pointof a post-‐antibiotic era, where common bacterial infections are no longer treatable with the antibiotic armamentarium that exists. In South Africa, t
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he identification of the first case of pan-‐resistant Klebsiella pneumoniae(Brink et al, J Clin Microbiol. 2013;51(1):369-‐72) marks a watershed moment and highlights ourtip of the antibiotic resistance ‘iceberg’ in this country. Multi-‐drug resistant (MDR)-‐bacterial infections, predominantly in Gram-‐negative bacteria such as Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosaand Acinetobacter baumanniiare now commonplace in South African hospitals. Whilst a number of expensive new antibiotics for Gram-‐positive bacterial infections have been manufactured recently (some of which are licenced for usein South Africa), no new antibiotics active against Gram-‐negative infections are expected in the next 10-‐15years. Hence what we have now, needs conserving
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Formularies are lists of antibiotics that are suggested for certain healthcare settings. In developing a recommended formulary, countries should consider the needs of patients and facilities where they receive care. For example, clinicians in rural
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or primary health centers may need wide access to first-line antibiotics (e.g., penicillin, ampicillin, TMP-SMX), but last resort antibiotics such as carbapenems or colistin might be limited to tertiary care hospitals. Efforts to create antibiotic formularies may be linked to efforts within countries to create or update essential medicine lists (EML).
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Why are experts concerned about COVID-19 and antibiotics? And what can you do about it? Learn about antibiotics and COVID-19 from WHO’s Dr Hanan Balkhy in Science in 5
Antibiotics – What Is Resistance?
recommended
German Agency for Quality in Medicine (ÄZQ)
(2012)
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Patient information on resistance to antibiotics. English version. Also available in: Arabic, French, German, Russian, Turkish, Spanish. For other versions go to: http://www.patienten-information.de/kurzinformationen/arzneimittel-und-impfungen/resis
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tenzen-gegen-antibiotika
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Antibiotics have been a critical public health tool since the discovery of Penicillin in 1928, saving the lives of millions of people around the world. In developing country like ours, where the burden of treatable disease is very high and access to
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health facilities and laboratories is difficult, antibiotics have long acted as miracle drugs. Today, however, the emergence of drug
resistance in bacteria is reversing the miracles of the past eighty years, with drug choices for the treatment of many bacterial infections becoming increasingly limited, expensive, and in some cases, nonexistent. Diseases previously regarded as relatively easy to manage are much harder to treat as doctors must use “last-resort” drugs that are more costly, take longer to work
and are often unavailable or unaffordable in developing countries. Moreover, regular prescription of antibiotics, random treatment, over the counter sales, inadequate dosage, inclusion of antibiotics in animal feeds and agriculture has contributed equally to emergence of antibiotics resistance as silent epidemic within the country.
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The Core Elements of Outpatient Antibiotic Stewardship provides a framework for antibiotic stewardship for outpatient clinicians and facilities that routinely provide antibiotic treatment. This report augments existing guidance for other clinical settings. In 2014 and 2015, respectively, CDC release
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d the Core Elements of Hospital Antibiotic Stewardship Programs and the Core Elements of Antibiotic Stewardship for Nursing Homes. Antibiotic stewardship is the effort to measure and improve how antibiotics are prescribed by clinicians and used by patients. Improving antibiotic prescribing involves implementing effective strategies to modify prescribing practices to align them with evidence-based recommendations for diagnosis and management.
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Patient information on treatment with antibiotics. English version. Also available in: Arabic, German, French, Russian, Spanish, Turkish. For other language versions go to: http://www.patienten-information.de/kurzinformationen/arzneimittel-und-impfu
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ngen/antibiotika
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Antibiotics only fight infections caused by bacteria. Like all drugs, they can be harmful and should only be used when necessary. Taking antibiotics when you have a virus can do more harm than good:
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you will still feel sick and the antibiotic could give you a skin rash, diarrhea, a yeast infection, or worse.
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The toolkit offers advice on how national public health authorities could engage with primary care prescribers so as to promote appropriate and responsible use of antibiotics. The toolkit contains template materials and some suggest
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ed key messages for health professionals, ideas for awareness raising activities, and suggested tactics for getting the messages across to both primary care providers and patients regarding prudent use of antibiotics.
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It is estimated that around 2 billion people worldwide do not have access to essential medicines. Access to medicines in the Eastern Mediterranean Region varies among countries, depending on their income level and allocation of domestic resources to medicine and vaccine procurement. Access to safe a
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nd effective antibiotics remains a major challenge, especially for low- and middleincome countries. Barriers to access include high prices for new products, weak regulatory systems, substandard and falsified antibiotics, shortages of essential antimicrobials and inefficient procurement and supply management systems.
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Nosocomial infections, or hospital-acquired infec-tions (HAI), are among the most significant causesof morbidity and mortality in healthcare settingsthroughout the world.Prevention of HAIs iscentral to providing high quality and safe health-care, even in settings with limited resources.Transmi
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ssion of infectious agents between patientsby health workers and irrational use of antibioticsare two important preventable factors involved inmany HAIs.
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verall strategy and objective of the European Antibiotic Awareness Day The overall objective of the European Antibiotic Awareness Day is to support national activities aimed at raising awareness concerning the proper use of antibiotics so as to mai
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ntain the efficacy of antibiotics and avoid the emergence of resistant bacteria. To this aim, ECDC has decided to produce basic campaign communication materials that communicators in EU Member States can use in devising and implementing national campaigns. At the same time, a dedicated website will be launched in July 2008. These materials aim to provide a visual identity to the campaigns across the EU member states and make the messages more recognisable and consistent, thus memorable to the target audience. The choice of supporting visuals responds to the need of making the messages accessible to parents and young people, who represent the main target for the 2008 campaign.
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The era of effective antibiotics is coming to a close. In just a few generations, many “miracle medicines”have been beaten into ineffectiveness by the bacteria they were intended to eradicate. Bacteria quickly adapt to t
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he presence of antibacterial agents in order to survive. The misuse of antibiotics,which is an international problem, only exacerbates the steady evolution of resistance. In August 2010, the journal Lancet Infectious Diseases posed the question "Is this the end of antibiotics?" documentingthe rapid spread of multidrug-resistant bacteriaand predicting that 10 years remain in the useful life of many agents.
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This video explains what antibiotics and the microbiome are, how they work, and side effects that patients may experience. It also provides helpful questions for patients and their families to ask their health care providers when they have been pres
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cribed antibiotics.
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Antibiotics are important medicines for the treatment of bacterial infections in humans and animals. Since their introduction in the 1940’s antibiotics have saved countless lives and has made many
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medical techniques possible or safer.
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Control of pollution from antibiotic manufacturing is a key part of safeguarding the longevity of antibiotics for all. Pollution contributes to antibiotic resistance and potentially undermines the effectiveness of medicines. High levels of
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antibiotics in water bodies downstream of manufacturing sites have been widely documented. Currently, antibiotic pollution from manufacturing is largely unregulated and quality assurance criteria typically do not address environmental emissions.
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Swahili Version of Administration of parenteral antibiotics.Translation and voice over thanks to Alex Mureithi and Zawadi Machibya and their colleagues at the BBC Swahili Service.
This film shows how to give
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antibiotics correctly during pregnancy. It explains the “6 rights” of drug administration – the right drug, the right patient, the right dose, the right time, the right route, and the right paperwork.
The film is for use in health worker training
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Somali version of Administration of Parenteral antibiotics
Xanuunka inta uurka lagu jiro iyo gaar ahaan dhalmada ka danbaysa ama dhicisku waa arrinta muhuumka ah ee sababta xadiga jirada iyo dhimashada.
Filimkan wuxuu muujinayaa maareeynta ist
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icmaalka wanaagsan ee duraha jeermis dilaha ee loogu talogalay shaqaalaha caafimaadka iyo sida cad ee uu u xoojin lahaa lixda saxda ah ee maareeynta daawada.
Translation thanks to Aidarus Khalif and Fouzia Ismail and Abdirahman Dahir Aden at the Somaliland Nursing and midwifery Association (SLNMA).
Video also available in English, French and Swahili at: http://www.medicalaidfilms.org/film/how-to-give-intravenous-antibiotics-in-pregnancy/
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