In Kenya, the bacterial infections that contribute most to human disease are often those in which re-‐sistance is most evident. Examples are multidrug-‐resistant enteric bacterial pathogens such as typhoid, ... diarrhoeagenic Escherichia coli and invasive non-‐typhi salmonella, penicillin-‐resistant Streptococcus pneu-‐moniae, vancomycin-‐resistant enterococci, methicillin-‐resistant Staphylococcus aureus and multidrug-‐re-‐sistant Mycobacterium tuberculosis. Resistance to medicines commonly used to treat malaria is of particu-‐lar concern, as is the emerging resistance to anti-‐HIV drugs. Often, more expensive medicines are required to treat these infections, and this becomes a major challenge in resource-‐poor settings.
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Antimicrobial resistance (AMR) is an increasing worldwide public health problem with
important implications for the European Union (EU). When antibiotics become
ineffective, bacterial infections l...ead to increased morbidity, use of healthcare,
mortality and cost. Globally, estimates suggest that AMR leads to 700 000 deaths
per annum. For the EU, the European Centre for Disease Prevention and Control
(ECDC) has estimated that AMR currently causes 25 000 deaths annually and losses of
at least EUR 1.5 billion per annum in extra healthcare costs and productivity.
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Resistance happens when germs (bacteria and fungi) defeat the drugs designed to kill them. Any antibiotic use—in people, animals, or crops—can lead to ...>resistance. Resistant germs are a One Health problem—they can spread between people, animals, and the environment.
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A patient leaflet for primary care prescribers to hand out to patients: it explains to patients what antibiotic resistance is and why appropriate use of a...ntibiotics is important.
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The aim of the Toolbox is to provide inspiration and guidance on what can be done to address the pressing issue, based on scientific evidence and experiences gathered from those working in the field across the globe. The Toolbox is built on what has been done in the past in a variety of settings and... is aligned with ongoing and current initiatives. Throughout the Toolbox, a narrative text guides the user on how to work with the problem, combining practical advice with examples from the field, and providing links to external resources. Many resources can be adapted and implemented in a variety of contexts.
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Take Action on Antimicrobial Resistance. For Farmers
Take Action on Antimicrobial Resistance. For Veterinarians and Veterinarian students
Designed for healthcare professionals, this six-week course will inform you about – and empower you to provide – safe, high-quality antibiotic use. You’ll interact with colleagues globally, to understand what ...t medbox">antibiotic resistance means – and why the World Economic Forum has placed it alongside terrorism and climate change on its global risk register. You can also join the course in Spanish, Chinese, or Russian.
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The systematic surveillance of antibiotic use and antibiotic re-sistance prevalence in humans an...d animals is imperative for managingbacterial infectious disease (JPIAMR, 2019;WHO, 2015). Many low-income countries currently face substantial challenges in building national surveillance systems due to a lack of infrastructure and resources,resulting in a shortage of systematic data (FAO/OIE/WHO, 2018)
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A short movie about the history and the current status of antibiotics from the four week online course: Antibiotic Resistance: the silent tsunami, ...produced by ReAct and Uppsala University, Sweden.
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The infectious disease burden in India is among the highest in the world. A large amount of antibiot-ics are consumed in fighting infections, some of them saving lives, but every use adding to antibiotic...span> resistance in bacteria. Antibiotic use is increasing steadily (table 1), particularly certain antibiotic classes (beta-lactam antibacterials), most notably in the more prosperous states. Resistance follows in lock-step.
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Stenotrophomonas maltophiliais a nonfermenting Gram-negative rod that is ubiquitous in nature (predominantly occurring in aquatic environments and on plants). Biochemically, it iscatalase positive and oxidase negative, and it produces acid frommaltose (hence the name“maltophilia”). Due to it...s chargedcell wall surface and biofilm production, it may attach to and survive on abiotic surfaces in clinical settings (eg, central venouscatheters, disinfectant and hand-washing solutions, solutions for hemodialysis, endoscopes, inspiration/expiration circuits of ventilators, nebulizers, tap water, and showerheads).
Health Services Research and Managerial Epidemiology Volume 6: 1-9ªThe Author(s) 2019
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The Global Antibiotic Resistance Partnership (GARP) aims to address the challenge of antibiotic resista...nce by developing actionable Policy Proposals in Vietnam and four other low- and middle-income countries: China, India, Kenya and South Africa. GARP will develop the evidence base for Policy action on antibiotic resistance and identify policy opportunities where research, advocacy and information have the best chance of slowing the development and spread of resistance.
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The Global Antibiotic Resistance Partnership (GARP)-Mozambique team, in partnership with the Center for Disease Dynamics, Economics & Policy (CDDEP), has produced this report as part of a solid com-...mitment to develop actionable policy proposals to tackle antibiotic resistance and improve appropriate antibiotic access. It is the result of a thorough review of published and unpublished data on antibiotic resistance and a long internal consultation effort that engaged academic scientists, health professionals and other stakeholders within Mozambique.
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South Africa has faced many challenges over the past two decades, accomplishing profound positive changes in the social structure and government of the nation. This has not yet fully translated into better health for the population, however, particularly the poorest segment. In fact, the p...opulation has lost ground since the 1990s in virtually all important health indicators, leaving South Africa with a high burden of infectious disease.
August 2011, Vol. 101, No. 8 SAMJ
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At the Society's 2014 Annual Conference, Professor Laura Piddock was awarded the Society's Marjory Stephenson Prize. Her is her prize lecture, in which she talks about the mechanisms underlying antimicrobial resistance
An Action Framework and annexe to Immunization Agenda 2030 (Draft version)
27 January 2021
This paper focuses on the Sustainable Development Goals related to poverty, economic growth, inequality, health, food production and the environment. It presents concrete examples of the underlying and complex aspects of antibiotic ...ibute-to-highlight medbox">resistance and its impacts across different Sustainable Development Goals. The aim of this paper is to inform and stimulate discussions on how to further advance the implementation of 2030 Agenda for Sustainable Development, the Global Action Plan on Antimicrobial Resistance, National Action plans on Antimicrobial Resistance, as well as work within all sectors that affect and are affected by antibiotic resistance
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BMJ Global Health Vol.4 (2019 no.4
The Drug Resistance Index (DRI) is proposed as measure of antibiotic effectiveness in a given country, by combining, in a single metric the use of various ...lass="attribute-to-highlight medbox">antibiotic groups and the resistance proportions of several pathogens.It is a complicated measure that gives results that cannot be understood by common knowledge and logic. The DRI conveys a wrong message.
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