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PLOS ONE | https://doi.org/10.1371/journal.pone.0210937 February 5, 2019
Guidelines on post-exposure prophylaxis for HIV and the use of co-trimoxazole prophylaxis for HIV-related infections among adults, adolescents, and children: recommendations for a public health approach : December 2014 supplement to the 2013 Consoli ... more
1PEP GUIDELINES | 2019 EDITION. The prevalence of both HIV and Hepatitis B is high in South Africa therefore there is a significant risk of acquiring these infections following exposure to infected material. Studies suggest that post- exposure prophylaxis (PEP) with highly active antiretroviral trea ... more
Cochrane Database of Systematic Reviews 2021, Issue 2. Art. No.: CD009593. DOI: 10.1002/14651858.CD009593.pub5.
The Adult Standard Treatment Guidelines and Essential Medicines List for Hospital Level provide a platform for transparency to enable equitable access to safe, effective, and affordable treatment options at hospital level taking into consideration the changing clinical needs of our population and th ... more
Epidemiology Chagas disease (American trypanosomiasis) is caused by the protozoan parasite Trypanosoma cruzi, and transmitted to humans by infected triatomine bugs, and less commonly by transfusion, organ transplant, from mother to infant, and in rare instances, by ingestion of contaminated food or ... more
Adolescence, defined as the period between 10 and 19 years of age, is a developmental stage during which many psychosocial and mental health challenges emerge. There is a well-established link between mental health and HIV outcomes. Adolescents and young a ... more
Adolescence, defined as the period between 10 and 19 years of age, is a developmental stage during which many psychosocial and mental health challenges emerge (1). Studies show that 34.6% of all mental health disorders begin by 14 years of age and 62.5% by 25 years (2). More broadly, adolescents ar ... more
The purpose of the guideline is to provide evidence-based recommendations on nonsurgical interventions for chronic primary LBP (CPLBP) in adults, including older people, that can be delivered in primary and community care settings to improve CPLBP-r ... more
The purpose of the guideline is to provide evidence-based recommendations on nonsurgical interventions for chronic primary LBP (CPLBP) in adults, including older people, that can be delivered in primary and community care settings to improve CPLBP-r ... more
Clinical guideline, Methods, Evidence and Recommendations In this guideline the following is covered: information needs of people with chronic hep titis B and their carers; where children, young people and adults with chronic hepatitis B a- shoul ... more
Chronic Non Communicable Diseases. Case Management Desk Guide
Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa. These guidelines update the recommendations that were first released i ... more
The new guidelines provide public health guidance on pharmacological agents for managing hyperglycaemia in type 1 and type 2 diabetes for use in primary health-care in low-resource settings. These guidelines update the recommendations for managing hyperglycaemia in the WHO Package of Essential NCD I ... more
Best practice guidelines are systematically developed statements designed to assist nurses working in partnership with persons and their families to make decisions about health care and services (Field & Lohr, 1990). This nursing Best Practice Guideline (BPG) is intended to replace the RNAO BPGs Scr ... more
15 January 2021
Cryptococcal disease, particularly cryptococcal meningitis is a significant cause of morbidity and mortality among people living with HIV with advanced HIV disease. It is estimated that it is responsible for nearly 19% of AIDS-related mortality, second only to tuberculosis. Rapid screening, diagnosi ... more
Diabetes mellitus (hereafter referred to as diabetes) is a chronic, progressive disease characterized by elevated blood glucose levels. Diabetes can lead to complications such as cardiovascular disease (CVD) and premature death, and can damage eyes, kidneys and nerves. Globally, more than 400 millio ... more
Asthma, hay fever and eczema are three common chronic conditions. There have been no recent multi-country data on the burden of these three conditions in adults; the aims of this study are to fill this evidence gap. The Global Asthma Network Phase ... more
Asthma is one of the most common non-communicable diseases globally. This study aimed to assess asthma medicine use, management plan availability, and disease control in childhood, adolescence, and adulthood across different country settings.
This document defines the framework for Malawi’s National HIV Programs. Considering public health benefits and risks, as well as funding and resource implications, deviations from these guidelines are not supported by the Ministry of Health.
2nd edition
National Guidelines on Nutrition, Care, Support, and Treatment (NCST) for Adolescents and Adults These guidelines are intended to: • Establish a consistent set of nutrition interventions and recommendations aimed at managing and preventing und ... more
Adults and adolescents 12+ years. Asthma medication options: Adjust treatment up and down for individual patient needs
Individual psychological help for adults impaired by distress in communities exposed to adversity. The manual describes a scalable psychological intervention called Problem Management Plus (PM+) for adult ... more
PSYCHOLOGICAL HELP FOR ADULTS IN COMMUNITIES EXPOSED TO ADVERSITY
SCOPING QUESTION: In adults with acute convulsive seizures, where intravenous access is available, which first-line anti- epileptic medication should be used to abort seizures when compared to comparator?
SCOPING QUESTION: For adults and children with medication-resistant convulsive epilepsy, which anti-epileptic medications produce benefits and/or harm in the specified outcomes when compared to a placebo or a comparator?
SCOPING QUESTION: In adults with established status epilepticus (i.e., seizures persisting after the first-line treatment with benzodiazepines [or benzodiazepines-resistant status epilepticus]), which anti-epileptic medications are associated with c ... more

Communicating with adolescents

Mental Health First Aid (Australia) (2019) C2
Guidelines for adults on how to communicate with adolescents about mental health problems and other sensitive topics Accessed: 31.03.2019
Q8.SCOPING QUESTION: In adults and older adolescents with depressive disorder, what is the comparative effectiveness of different formats of psychological treatments?
Group psychological help for adults impaired by distress in communities exposed to adversity With this manual, the World Health Organization (WHO) is responding to requests from colleagues around the world for a group version of the manual Problem ... more
96 million American adults - more than 1 - 3 - have prediabetes
Diabetes Burdens: 10.5% adults around the world are currently loving with diabetes.
Music therapy can help traumatized children and adults to stabilize and to create a safe space for the expression of feelings and thoughts. In a 1 day international symposium on Friday May 26, presenting lectures and workshops, we’ll highlight the ... more
How can parents and other adults help children and teens living with undiagnosed, untreated PTSD find the help they need? An understanding of the symptoms of PTSD is a good place to start. Some of the symptoms in children and teens are the same as t ... more
[Updated 2015] Scoping Question: In adults with acute convulsive seizures in first-level care or in the community (when no IV access is available), which antiepileptic medications produce benefits and/or harm when compared to comparator?
Module 12: Adolescents and young adults July 2018 Module 12: Adolescents and young adults. This module is for people who are interested in providing PrEP services to older adolescents and yo ... more
This leaflet provides support and advice for adults who are recovering from COVID-19. It can be used by individuals after hospitalization from the illness and those in the community who did not need hospitalization. The leaflet can complement care r ... more
A group-based stress managment course for adults. Self-Help Plus (SH+) is WHO’s 5-session stress management course for large groups of up to 30 people. It is delivered by supervised, non-specialist facilitators who complete a short training cours ... more
Guidelines for care of older adults with SARS CoV-2/COVID-19
Key facts - An estimated 1.28 billion adults aged 30–79 years worldwide have hypertension, most (two-thirds) living in low- and middle-income countries - An estimated 46% of adults with hyperten ... more
Q 2: How long should treatment with antidepressants continue in adults with depressive episode/disorder?
Guidelines for the Management of Urine Incontinence in Adults
TB treatment for children is fundamentally the same as for adults, with a combination of TB drugs needing to be taken for a number of months. TB treatment for children consists of an intensive phase followed by a continuation phase. The purpose of t ... more
Much of our knowledge about PTSD is based on studies of adults. As evidenced by the birth of new scientific disciplines (e.g., developmental translational neuroscience), it is clear that what we learn from research involving ... more
Assessment of the quality of institutional care for adults with psychosocial and intellectual disabilities in the WHO European Region. The specific objectives of the project were to address gaps in knowledge about the number and characteristics of ... more
Q7. SCOPING QUESTION: In adults with moderate-severe depressive disorder, what is the effectiveness and safety of antidepressant medication (ADM) in comparison with psychological treatment? The WHO mhGAP programme’s existing guidelines recommen ... more
Q14. SCOPING QUESTION: In adults with psychotic disorders (including schizophrenia), what is the comparative effectiveness and safety of second-generation antipsychotic medications?
The guidelines are to be used to guide the management of adults with lower respiratory tract infection (LRTI). As will be seen in the following text, this diagnosis, and the other clinical syndromes within this grouping, can be difficult to make acc ... more
The Rehabilitation self-management leaflet provides basic exercises and advice for adults who have been severely unwell and admitted to the hospital with COVID-19. The leaflet assist in self-rehabilitation and recovery management, addressing specifi ... more
The Rehabilitation self-management leaflet provides basic exercises and advice for adults who have been severely unwell and admitted to the hospital with COVID-19. The leaflet assist in self-rehabilitation and recovery management, addressing specifi ... more
The Rehabilitation self-management leaflet provides basic exercises and advice for adults who have been severely unwell and admitted to the hospital with COVID-19. The leaflet assist in self-rehabilitation and recovery management, addressing specifi ... more
Consensual Recommendation for treatment of COVID-19 in older adults
Key facts - A healthy diet helps to protect against malnutrition in all its forms, as well as noncommunicable diseases (NCDs), including diabetes, heart disease, stroke and cancer. - Unhealthy diet and lack of physical activity are leading global risks to health. - Healthy dietary practices start ... more
Bronchial asthma is the most frequent chronic respiratory disease in both adults and children. The prevalence and burden of asthma vary considerably between different regions of the world. Information on asthma in Africa is fragmentary and relativel ... more
SCOPING QUESTION:Which psychosocial interventions are effective in the treatment of psychostimulant dependence for adults and young people?
A workshop methodology for children, young people and adults The “Tree of Life” is a psychosocial support tool based on narrative practices that is designed to help participants accept the hardships of their past and identify the strengths that ... more
Advice on physical activity should be encouraged as part of treatment for adults with depressive episode/disorder with inactive lifestyles. In moderate and severe depression, this intervention should be considered as adjunct to antidepressants or br ... more
Accessed July 4, 2019 Around one in four adults has at least one mental health need at any time, and in the next 20 years the number of British people expected to suffer from dementia will grow by 40 per cent. Even though you might not be working i ... more
Safe disposal of children’s feces is as essential as the safe disposal of adults’ feces. Th is brief provides an overview of the available data on child feces disposal in Burkina Faso and concludes with ideas to strengthen safe disposal practice ... more
One booklet is called "Heart-to-Heart with My Child." Published for Rohingya adults and children, it conveys key child protection messages in accessible terms in both Rohingya and in English. The messages are illustrated with embroideries made by Ro ... more
According to WHO, around 22% of adults in conflict settings have mental health conditions. This is almost triple to non-conflict settings. There is no generally accepted estimate for children but it is clear that children who are refugees, IDPs or ... more
The new treatment recommendations that extend the 2018 treat all recommendation for adults with chronic HCV infection to include adolescents and children down to 3 years, and to align the existing recommended pangenotypic direct-acting antiviral (DA ... more
Diabetes is a significant public health issue that affects approximately one in 10 adults globally, with type 2 diabetes accounting for 90–95% of cases. This chronic condition causes considerable morbidity and mortality and is growing in impact, w ... more
Diabetes is a significant public health issue that affects approximately one in 10 adults globally, with type 2 diabetes accounting for 90–95% of cases. This chronic condition causes considerable morbidity and mortality and is growing in impact, w ... more
The following information provides guidance to health care providers attending to the medical needs of HIV-infected adults (including pregnant women) or children displaced from disaster areas who have not yet secured HIV care in the areas where they ... more
This guide summarises The Union's experience in developing approaches to integrated TB-HIV care for adults in resource-limited settings. It is recommended for health professionals at the implementation level and national programme staff in charge of ... more
Somali version of How Babies are made This is a film aimed at early teens and young adults. It describes what puberty is and how babies are made using a mixture of animation and expert advice as well as from young men and women in Nairobi. Tra ... more
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectiou ... more
This guideline covers diagnosing, monitoring and managing asthma in adults, young people and children. It aims to improve the accuracy of diagnosis, help people to control their asthma and reduce the risk of asthma attacks. It does not cover managin ... more

Addressing childhood trauma in a developmental context

Gregorowski, C. & Seedat, S. Journal of Child and Adolescent Mental Health (2013) CC
Traditionally, understanding of the psychiatric and psychological effects of trauma have been developed from studies with adults and then applied to trauma-exposed children with some modifications. While this is an important step to understanding th ... more
Q 4: Is behavioural activation better (more effective than/as safe as) than treatment as usual in adults with depressive episode/disorder?brief, structured psychological treatment in non-specialist health care settings better (more effective than/as ... more
The number of general health staff skilled in psychological treatment for depression is limited, and learning psychological treatments tends to require considerable training and supervision. Relaxation may be a relatively simple form of psychological treatment. It has been frequently studied in rese ... more
Q6: Is advice on physical activity better (more effective than/as safe as) than treatment as usual in adults with depressive episode/disorder with inactive lifestyles
Is your child’s ear hurting? It could be an ear infection. Children are more likely than adults to get ear infections. Talk to your child’s doctor about the best treatment. Some ear infections, such as middle ear infections, need antibiotic trea ... more
This module takes you through the NICE coronavirus disease (COVID-19) rapid guideline: critical care in adults, providing resources to support their recommendations and patient scenarios to demonstrate key learning points. Learning outcomes Afte ... more
This report provides an overview of the progress in the roll-out of COVID-19 vaccines in adults (aged 18 years and above) across EU/EEA Member States. It presents the number of vaccine doses distributed by manufacturers to each Member State for the ... more
SARS-CoV-2 infections among children and adolescents cause less severe illness and fewer deaths compared to adults. While a less severe course of infection is a positive outcome, there are concerns that mild symptoms may have led to less testing, re ... more
SARS-CoV-2 infections among children and adolescents cause less severe illness and fewer deaths compared to adults. While a less severe course of infection is a positive outcome, there are concerns that mild symptoms may have led to less testing, re ... more
SARS-CoV-2 infections among children and adolescents cause less severe illness and fewer deaths compared to adults. While a less severe course of infection is a positive outcome, there are concerns that mild symptoms may have led to less testing, re ... more
This training guide applies a participatory approach, reflecting the considerable evidence that adults learn best by practicing and reflecting on their experiences. It thus emphasizes exercises to improve skills in counseling that support clients to ... more
Many of the countries in the European Region receiving refugees from Ukraine are already offering vaccination services to children and adults. This is important to mitigate the risk of COVID-19 transmission among people travelling or living in close ... more
For 100 cases among which 60 cases of children ≥ 5 years old and 40 cases of children < 5 years old and adults. The new Pneumonia kit 2020 is specially designed to provide sufficient child-size antibiotics to treat pneumonia, targeting children ... more
Diabetes is a major public health problem in the Americas and worldwide, demanding special attention and integrated response. It is estimated that more than 62 million adults are living with diabetes in the Americas. The projections show that diabet ... more
PEN-Plus is an integrated care delivery strategy focused on alleviating the noncommunicable disease (NCD) burden among the poorest children and young adults by increasing the accessibility and quality of chronic care services for severe NCDs – suc ... more
PEN-Plus is an integrated care delivery strategy focused on alleviating the noncommunicable disease (NCD) burden among the poorest children and young adults by increasing the accessibility and quality of chronic care services for severe NCDs—such ... more
On average across 34 countries, more than half of all adults surveyed (56%) say climate change has already had a severe effect in the area where they live. More than seven in ten (71%), including a majority in every single country, expect climate ch ... more
Almost all populations are consuming too much sodium. The global mean intake of adults is 4310 mg/day sodium (equivalent to 10.78 g/day salt). This is more than double the World Health Organization recommendation for ... more
Diabetes is a major public health problem in the Americas and worldwide, demanding special attention and integrated response. It is estimated that more than 62 million adults are living with diabetes in the Americas. The projections show that diabet ... more
This guide can be used to train medical officers to ensure BP is measured for all adults visiting the OPD, treat all patients with high BP, initiate treatment as per protocol, counsel patients for follow-up, refer patients to local care, and report ... more
Asthma is the most common noncommunicable disease in children, and among the most common in adults. According to the most recent estimates from the Global Asthma Network Phase I study, around one in 10 children and ... more
Chapter 10 of Pediatric Surgery: This chapter provides an overview of some of the challenges when providing anaesthesia care for children in Africa. The chapter reviews the cardiac, respiratory, and renal differences of children in comparison to adults ... more
The INEE Minimum Standards Handbook is the only global tool that articulates the minimum level of educational quality and access in emergencies through to recovery. The Minimum Standards express a commitment that all individuals—children, youth and adult ... more
A handy desk reference tool for primary level health workers. The Adolescent Job Aid is a handy desk reference tool for health workers (trained and registered doctors, nurses and clinical officers) who provide services to children, adolescents and adults ... more
In the area of nutrition and HIV, children deserve special attention because of their additional needs to ensure growth and development and their dependency on adults for adequate care. It was therefore proposed to first develop guidelines for chil ... more