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Five years after a global commitment to Fast-Track the HIV response and end AIDS by 2030, the world is off track. A promise to build on the momentum created in the first decade of the twenty-first century by front-loading investment and accelerating HIV service provision has been fulfilled by too fe
...
w countries
more
Effective antibiotics are essential for childrens’ survival
Five years after a global commitment to Fast-Track the HIV response and end AIDS by 2030, the world is off track. A promise to build on the momentum created in the first decade of the twenty-first century by front-loading investment and accelerating HIV service provision has been fulfilled by too fe
...
w countries.
more
AMCC, a Non-Governmental Organization (NGO) association governed by the law of 1901, the French branch of the INCTR (International Network for Treatment and Research on Cancer) mainly oriented towards women's and children's cancers, aims to strength
...
en the fight against cancer in low- and middle-income countries through training, education, teaching, research with support for therapeutic care.
more
Government of Nepal has an obligation to ensure availability of affordable and high quality basic health care services to its population
Cystic echinococcosis (CE) is a well-known neglected parasitic disease. However, evidence supporting the four current treatment modalities is inadequate, and treatment options remain controversial.
...
The aim of this work is to analyse the available data to answer clinical questions regarding medical treatment of CE.
more
WHO Treatment Guidelines for Drug-Resistant Tuberculosis, 2016 Update
recommended
Dennis Falzon, Elizabeth Harausz, Ernesto Jaramillo et al.
World Health Organization (WHO)
(2016)
C_WHO
Accessed Febr. 6, 2020
Despite being a curable and preventable disease, tuberculosis (TB) remains as one of the major challenges for health systems, globally. Every year, TB affects more than 10 million people and kills more than 1.4 million people. WHO’s Digital Health for the End TB Strategy – an Agenda for Action o
...
utlines a conceptual framework in which advantageously positioned digital health solutions are matched to the most urgent needs of TB programmes. Video-supported treatment is a component of one of the four core functions of this framework, the Patient Care domain, and primarily supports the first pillar of the End TB Strategy. This quick guide provides information on the solutions available for asynchronous modes of video communication and how these can be of use to TB programmes.
more
The link between cholera in pregnancy and negative childbirth outcomes has been observed since the
19th century, but there is currently no clear understanding of the extent nor the mechanisms to inform
treatment guidelines. The recommendations in
...
this Interim Technical Note are based on current
knowledge, including documented experiences of treating pregnant women with cholera during
epidemics.
more
Diarrhoea Treatment Guidelines
recommended
Including new recommendations for the use of ORS and zinc Supplementation for Clinic-Based Healthcare Workers
Standard treatment guidelines
recommended
A rapid situation analysis in three districts
A Training Curriculum for Multidisciplinary Healthcare Teams. This innovative training package aims to empower multidisciplinary health workers to have the confidence and skills to provide comprehensive, youth-friendly HIV services that support adolescents’ healthy development, psychosocial well b
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eing, retention, adherence, sexual and reproductive health, and eventual transition to adult HIV services.
more
Adolescent HIV Care and Treatment: A Training Curriculum for Health Workers - Participant Manual
T. Colton; V. Allread; E. Abrams; et al.
ICAP Columbia University (Mailman School of Public Health)
(2012)
C2
National Antiretroviral Treatment Guidelines for Adults, Adolescents and Children
Elly T. Katabira,Moses R. Kamya, Israel Kalyesubula, Alice Namale
Federal Ministry of Health, Uganda
(2009)
C1
Accessed Febr. 6, 2020
Lessons from the STEP-TB Project.
Accessed November 2017.
2006-2008 programme report
Antiretroviral treatment outcomes from a nurse-driven, community-supported HIV/AIDS treatment programme in rural Lesotho: observational cohort assessment at two years
Cohen, R., Sharonann, L., Bygrave, H., et al
Journal of the International AIDS Society (JIAS)
(2009)
CC
Defending Rights
Breaking Barriers
Reaching People with HIV Services
Global Aids Update 2019
Paediatric - HIV Care and Treatment
USAID; Pata; South to South Zoe life; et al.
(2019)
C2
Accessed: 08.10.2019
Accessed Febr. 6, 2020
Accessed Febr. 6, 2020
Accessed Febr. 6, 2020
Accessed Febr. 6, 2020
Accessed Febr. 6, 2020
accessed Febr. 6, 2020
Accessed Febr. 6, 2020
Accessed Febr. 6, 2020
Accessed Febr. 6, 2020
Adolescent HIV Care and Treatment: A Training Curriculum for Health Workers - Trainer Manual (Introduction Section 1-3)
T. Colton; V. Allread; E. Abrams; et al.
ICAP Columbia University (Mailman School of Public Health)
(2012)
C2
Trainer Manual Introduction (Section 1-3)
The product of all this work is the Standard Treatment Guideline and Essential Medicines List of Common Medical Conditions in the Kingdom of Swaziland. These systematically developed statements are designed to assist practitioners in making decision
...
s about appropriate treatment for specific clinical conditions. They are meant to reflect expert consensus based on a review of current and published scientific evidence of acceptable approaches to diagnosis, man-agement, or prevention of specific conditions.It is enlightening to note that section A of the document contains the STG, and effort has been made to have the conditions commonly encountered in Swaziland classified according to systems. Written in simple, clear language, each section consists of a short definition followed by common symptoms and signs of the disease or condition and then management (pharmacological and nonpharmacological)
more
4 April 2020
This interim guidance on oxygen sources and distribution strategies for COVID-19 treatment has been adapted from WHO and UNICEF’s technical specifications and guidance for oxygen therapy devices, which is part of the WHO medical devi
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ce technical series. This guidance is intended for health facility administrators, clinical decision-makers, procurement officers, planning officers, biomedical engineers, infrastructure engineers and policy-makers. It describes how to quantify oxygen demand, identify oxygen sources that are available, and select appropriate surge sources to best respond to COVID-19 patients’ needs, especially in low-and-middle income countries.
more
This update of the Guidelines for poison control, entitled Guidelines for establishing a poison centre, reflects the development of the role of poison centres in public health and the sound management of chemicals, described in section 1, and the op
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portunities provided by new technology. Assessments carried out under the IHR show
continuing gaps in capacity for managing chemicals (2). In particular, many countries still lack access to poison
centre services (3). There is therefore demand for updated guidance.
more
The Adult Standard Treatment Guidelines and Essential Medicines List for Hospital Level provide a platform for transparency to enable equitable access to safe, effective, and affordable treatment op
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tions at hospital level taking into consideration the changing clinical needs of our population and the pragmatic implications of the introducing a new health technology.
more
The results of the SHINE trial have been published in the NEJM today. SHINE looked at whether treatment for children with minimal TB could be reduced from 6 months to 4 months. It found that the four month
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treatment was as good as the standard six months treatment for children with minimal TB
more
N Engl J Med 2022; 386:911-922, DOI: 10.1056/NEJMoa2104535
Four months of antituberculosis treatment was noninferior to 6 months of treatment in children with drug-susceptible, nonsevere, smear-neg
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ative tuberculosis (SHINE Study)
more
Standard Treatment Guidelines and Essential Medicines List for South Africa : Primary Healthcare Level 2020 edition
the Essential Drugs Programme, the PHCAdult Hospital Level Expert review Committee, the National Essential Medicines List Committee
National Department of Health South Africa
(2020)
CC
The PHC STGs and EML should be used by healthcare workers providing care at clinics, community health centres, and gateway clinics at hospitals.
Pharmaceutical and Therapeutics Committees (PTCs) are responsible for ensuring the availability of medicines listed in the PHC EML at those facilities, as
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well as at higher levels of care.
more
In Paraguay, 1.8% of the population are indigenous people. The Maká community
29 mainly live in urbanized areas in the Central Region. This study focuses on the epidemiology
30 of tuberculosis (TB) among indigenous Maká and the non-indigenous people living in the
31 Central Region, the biggest
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metropolitan area of the Paraguay.
more
The leishmaniases are a group of diseases caused by Leishmania spp., which occur in cutaneous, mucocutaneous and visceral forms. They are neglected tropical diseases (NTDs), which disproportionately affect marginalized populations who have limited access to health care. HIV co-infected patients with
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Leishmania infection are highly infectious to sandflies, and an increase in the coinfection rate in an endemic area is likely to increase the effective infective reservoir.
more
Updated recommendations on treatment of adolescents and children with chronic HCV infection
recommended
The new treatment recommendations that extend the 2018 treat all recommendation for adults with chronic HCV infection to include adolescents and children down to 3 years, and to align the existing recommended pangenotypic direct-acting antiviral (DA
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A) regimens (SOF/DCV, SOF/VEL and G/P) for adults, to those for adolescents and children. This alignment is expected to simplify procurement, promote access to treatment among children in low- and middle-income countries and contribute to global efforts to eliminate the disease
more
These guidelines provide updated evidence-based recommendations on the priority HCV-related topics from the 2018 WHO Guidelines for the care and treatment of persons diagnosed with chronic hepatitis C infection and the 2017 WHO Guidelines on hepatit
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is B and C testing. These priority areas are:
direct-acting antiviral (DAA) treatment of adolescents and children ages ≥3 years of age
simplified HCV service delivery (decentralization, integration and task sharing)
HCV diagnostics – use of point-of-care (POC) HCV ribonucleic acid (RNA) assays and reflex HCV RNA testing.
These guidelines also update existing chapters without new recommendations, such as the inclusion of new manufacturers’ protocols on the use of dried blood spot (DBS) for HCV RNA testing and new data to inform the limit of detection for HCV RNA assays as a test of cure, in addition to their use for diagnosis.
more
Snakebite is an acute life threatening time limiting medical emergency. It is a preventable public
health hazard often faced by rural population in tropical and subtropical countries with heavy
rainfall and humid climate.
Approximately 80% of the 463 million adults worldwide with diabetes live in low-income and middle-income countries (LMICs). A major obstacle to designing evidence-based policies to improve diabetes outcomes in LMICs is the scarce availability of nationally representative data on the current patterns
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of treatment coverage. The objectives of this study were to estimate the proportion of adults with diabetes in LMICs who receive coverage of recommended pharmacological and non-pharmacological diabetes treatment; and to describe country-level and individual-level characteristics that are associated with treatment.
more
The "Primary Healthcare Standard Treatment Guidelines and Essential Medicines List" by the South African National Department of Health provides evidence-based guidelines for diagnosing and managing common medical conditions at the primary healthcare
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level. This document includes treatment protocols for various health issues, such as infections, chronic diseases, maternal and child health, mental health, and emergency care. It aims to standardize care, promote rational medicine use, and ensure equitable access to essential medications across South Africa. The guidelines emphasize prevention, accurate diagnosis, and efficient treatment strategies to improve patient outcomes.
more
Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence
World Health Organization
(2009)
C_WHO
To provide a foundation for the strategic policy and programme development needed to ensure the sustainable implementation of effective interventions for reducing the global burden of PPH
The Manual for Participants is primarily meant for the participants of a 3 and a half day training course in Emergency Triage, Assessment and Treatment.
Training Manual
New edition
This technical brief presents the current options for safe storage and point of use water treatment. It is intended to help field staff working in a variety of locations to decide upon the most appropriate course of action for providing safe water f
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or the communities in which they work. The effectiveness of household water treatment options now and in the future rely to a huge extent on user compliance; it is critical that users are involved in the decision making process, and are aware of the purpose, how to use, maintain and manage their household water options. The brief therefore details relevant hygiene promotion steps for the different treatment options.
more
Cervical intraepithelial neoplasia (CIN) is a premalignant lesion that may exist at any one of three stages: CIN1, CIN2, or CIN3. If left untreated, CIN2 or CIN3 (collectively referred to as CIN2+) can progress to cervical cancer. Instead of screening and diagnosis by the standard sequence of cytolo
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gy, colposcopy, biopsy, and histological confirmation of CIN, an alternative method is to use a ‘screen-and-treat’ approach in which the treatment decision is based on a screening test and treatment is provided soon or, ideally, immediately after a positive screening test. This guideline provides recommendations for strategies for a screen-and-treat programme
more
Global update on HIV treatment 2013: Results, impact and opportunities
World Health Organization; UNICEF; UNAIDS
(2013)
Chapter 1 provides new data on the latest developments in the global treatment effort, highlighting positive trends as well as aspects that require improvement. Chapter 2 summarizes the impact of the scale-up in reducing AIDS-related mortality and n
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ew HIV infections. Chapter 3 examines the sequence of steps in the continuum of care from HIV diagnosis to successful provision of ART services and outlines key supportive innovations. Chapter 4 discusses the implications and anticipated impact of the new "Consolidated guidelines on the use of ARV drugs for treating and preventing HIV infection
more
Accessed at March 2014
The objectives of these WHO guidelines are to provide updated evidence- based recommendations for the treatment of persons with hepatitis C infection using, where possible, all DAA-only combinations. The guidelines also provide recommendations on th
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e preferred regimens based on a patient’s HCV genotype and clinical history, and assess the appropriateness of continued use of certain medicines. This document also includes existing recommendations on screening for HCV infection and care of persons infected with HCV that were first issued in 2014
more
Revised WHO classification and treatment of childhood pneumonia at health facilities
World Health Organization
(2014)
The revised guidelines present two major changes to existing guidelines: (A) there are now just 2 categories of pneumonia instead of 3 (“pneumonia” which is treated at home with oral amoxicillin and “severe pneumonia” which requires injectable antibiotics) and (B) oral amoxicillin replaces o
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ral cotrimoxazole as first line treatment, preferably in 250mg dispersible tablet form, twice daily for five days which can be reduced to three days in low HIV settings.
more
Fourth Edition
Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection
recommended
The recommendations in these guidelines promote the use of simple, non-invasive diagnostic tests to assess the stage of liver disease and eligibility for treatment; prioritize treatment for those wi
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th most advanced liver disease and at greatest risk of mortality; and recommend the preferred use of nucleos(t)ide analogues with a high barrier to drug resistance (tenofovir and entecavir, and entecavir in children aged 2–11 years) for first- and second-line treatment. Recommendations for the treatment of HBV/HIV-coinfected persons are based on the WHO 2013 Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection, which will be updated in 2015.
more
Skin and mucosal conditions are extremely common in all children and adults in particular in HIV-infected adults and children and are one of the commonest daily management problems faced by health care workers caring for patients with HIV infection
Expert opinion of the European Tuberculosis Laboratory Initiative core group members for the WHO European Region.
Aлгоритм лабораторной диагностики и мониторинга лечения туберкулеза легких и туберкулеза с лекарственной устойчивостью на основе применения современных быстрых
...
молекулярных методов.
Экспертное заключение членов основной группы Европейской лабораторной инициативы, подготовленное для Европейского региона ВОЗ.
more
WHO/CDS/TB/2002.300
Pathak et al. (2016), PeerJ, DOI 10.7717/peerj.1738; 1-14
Adherence to Treatment for HIV A Training Curriculum for Counselors - Participant Manual
F. Saini; Dr. V. R. Kandula; G. Venugopal
Engender Health Society (Improving Women's Health Worldwide); CII Confederation of Indian Industry; Population Foundation of India; et al.
(2006)
C2
An in-depth analysis of the health-seeking behaviour of patients and health system response in seven countries of the Eastern Mediterranean Region