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The occurrence of a high percentage of couterfeit medicines on the global medicines market is often attributed to a lack of effective regulation and a weak enforcement capacity. This review, while focusing on counterfeit medicines and medical devices in developing countries, will present information ... more

Laboratory diagnosis of Buruli ulcer

Portaels, F- World Health Organization WHO (2014) C_WHO
A manual for health care providers. This manual provides expert guidance on the laboratory techniques and procedures used in the diagnosis of Buruli ulcer, a disease caused by Mycobacterium ulcerans. Aimed at laboratory technicians and scientists working on this disease, the manual details the exac ... more
Plos Neglected Tropical Diseases 8(11): e3229 (20 November 2014)
Baseado no livro Preparación y respuesta ante la eventual introducción del virus chikungunya en las américas
Global Health Science and Practice. First published online November 12, 2015
Interim guidance for entomologists. This document describes selected sampling methods that can be used to conduct surveillance of Aedes mosquitoes, pupae and oviposition. It is intended for qualified entomologists at national and sub-national level who are responsible for the surveillance of local ... more
This Training module on malaria elimination has been developed by WHO to support health professionals in planning, managing, monitoring and evaluating malaria elimination programmes
Methodological field approaches for scientists with a basic background in entomology to prepare and implement a yellow fever entomological assessment during outbreaks
SOP- Quality Assurance of Malaria Diagnostic Tests
Bulletin of the World Health Organization; http://dx.doi.org/10.2471/BLT.16.176677
Cochrane Database Syst Rev. 2016 Jul 1; (6): 1–61 -Published online 2016 July 1
2nd edition
With the increase in frequency of disasters, there is a need to improve early warning systems (EWS) for EA to reduce the risks faced by children and their families. As a consequence, the term early warning, early action (EWEA) has become increasingly common among those responding to slow-onset disas ... more
"Achieving, maintaining and improving accuracy, timeliness and reliability are major challenges for health laboratories. Countries worldwide committed themselves to build national capacities for the detection of, and response to, public health events of international concern when they decided to eng ... more
3rd Edition. Vol.1
Lymphatic filariasis is a vector-borne neglected tropical disease that causes damage of the lymphatic system and can lead to lymphoedema (elephantiasis) and hydrocele in infected individuals. The global baseline estimate of persons affected by lymphatic filariasis is 25 million men with hydrocele an ... more
WHO/CDS/CSR/EDC/99.2 Plague Manual Epidemiology, Distribution, Surveillance and Control
Statement Impact of migration on infectious diseases in Europe | August 2007 | 1-7
BMC Infectious Diseases 2012, 12:352/1471-2334/12/352
treat TB Description of Research Outputs, 2009 - 2014
This manual is intended to enable WASH practitioners who work in Mozambique to contribute to the reduction of WASH-preventable NTDs.
Mem Inst Oswaldo Cruz , Rio de Janeiro, Vol. 110 (3): 377-386, May 2015
The main objective of the 2014-15 RDHS was to obtain current information on demographic and health indicators, including family planning; maternal mortality; infant and child mortality; nutrition status of mothers and children; prenatal care, delivery, and postnatal care; childhood diseases; and ped ... more
Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa. These guidelines update the recommendations that were first released i ... more
Since 2000, concerted efforts by national programmes, supported by public–private partnerships, nongovernmental organizations, donors and academia under the auspices and coordination of the World Health Organization (WHO), have produced important achievements in the control of human African trypan ... more
(African Development Bank policy research document 1)
The report examines financing in the battle against malaria, focusing on the role of foreign aid. It analyzes whether or not a disease such as malaria can be controlled or eliminated in Africa without health aid. It also presents a theoretic ... more
Review of International, Regional and National Policies and Legal Frameworks that Promote Migrants and Mobile Populations' Access to Health and Malaria Services in the Greater Mekong Subregion (Cambodia, Lao People's Democratic Republic, Myanmar, Thailand and Viet Nam)
Migrants and mobile popul ... more
The skin of a patient is the first and most visible structure of the body that any health-care worker encounters during the course of an examination. To the patient, it is also highly visible, and any disease that affects it is noticeable and will have an impact on personal and social well-being. Th ... more
Recent efforts to fight malaria in the Greater Mekong Subregion (GMS) have yielded impressive results. According to the latest WHO estimates, the six GMS countries cut their malaria case incidence by an estimated 54% between 2012 and 2015. Malaria death rates fell by 84% over the same period.
I ... more
A nationwide survey of a representative sample of health facilities across public health services in all states and regions of Myanmar has been undertaken since 2014 to track Reproductive Health Commodity Security (RHCS) indicators, such as the availability of reproductive health (RH) commodities; t ... more
The objective of this paper is to summarise and critically review the available data about onchocerciasis in Mozambique, in order to report epidemiological and clinical aspects related to the disease and identify gaps in knowledge. The paper is intended to raise awareness of the existence and import ... more
PLoS ONE 13(8): e0202499. https://doi.org/10.1371/journal.pone.0202499 This was a school-based cross-sectional study conducted in 2015 among 305 school children aged 7–16 years from two primary schools located in Ilemela and Magu Districts, north-western Tanzania. Single stool and urine samples w ... more
The new WHO Guidelines on Sanitation and Health summarize the evidence on the effectiveness of a range of sanitation interventions and provide a comprehensive framework for health-protecting sanitation, covering policy and governance measures, implementation of sanitation technologies, systems and b ... more
Since the beginning of December a significant increase in the incidence of new cases has been observed particularly along the corridor towards the large urban center of Butembo (health zones of Butembo and Katwa) and beyond in the zone of Kayna health center located about 150 km from Goma. In additi ... more
Report for WHO Meningitis guideline revision Dr Thomas Waite, April 2014 Field Epidemiology Services, Public Health England; UK
The primary audience for this guidance is persons working directly in vector-borne disease prevention and control, including programme managers, researchers and field workers. A brief technical background is provided for the benefit of persons without expertise in vector-borne diseases; readers ... more
Afr J Psychiatry 2011;14:200-207
The updated List of Essential Diagnostics contains 46 general tests that can be used for routine patient care as well as for the detection and diagnosis of a wide array of disease conditions, and 69 tests intended for the detection, diagnosis and monitoring of specific diseases. The List is divid ... more
The idea to the ANDEMIA online course manual is based on the challenge that resources for sending ANDEMIA students to a variety of face to face courses is limited not only due to financial but also time constraints. Online course provide a good basis for the students, Master, PhD and Post Docs to pr ... more
En la presente guía de capacitación se explica cómo reconocer los signos y los síntomas de las enfermedades tropicales desatendidas de la piel a partir de sus características visibles. También contiene información sobre cómo diagnosticar y tratar los problemas frecuentes de la piel que puede ... more
Este guia de treinamento explica como identificar os sinais e sintomas das doenças tropicais negligenciadas da pele por meio de suas características visíveis. Contém ainda informações sobre métodos de diagnóstico e manejo de problemas cutâneos comuns que os profissionais de saúde da linha ... more
Esta guía está enfocada en emitir recomendaciones para el diagnóstico y el tratamiento de la enfermedad de Chagas, como infección por Trypanosoma cruzi, agente protozoario de una parasitosis sistémica. Metodología: La presente guía de práctica clínica fue confeccionada siguiendo los método ... more
This document focuses on making recommendations for the diagnosis and treatment of Chagas disease, an infection caused by Trypanosoma cruzi, the protozoan agent of a systemic parasitic disease. Methodology: These clinical practice guidelines were prepared following the WHO handbook for guideline dev ... more
During the past five decades, the incidence of dengue has increased 30-fold. Some 50–100 million new infections are estimated to occur annually in more than 100 endemic countries, with a documented further spread to previously unaffected areas; every year hundreds of thousands of severe cases ari ... more
Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 19, No. 9, September 2013
Dieses Kurzdossier konzentriert sich besonders auf den Zusammenhang zwischen zwei übertragbaren tropischen Armutserkrankungen – dem Wurmbefall des Darms durch Geohelminthen wie Spul-, Peitschen- und Hakenwürmer sowie der Schistosomiasis (Bilharziose). Es zeigt Möglichkeiten zu deren Bekämpf ... more
Constituting the second part of the World Drug Report 2022, the present booklet contains an overview of the global demand for and supply of drugs. The first chapter of the booklet begins with the latest estimates of the number of people who use drugs, the distribution of those users by type of drug ... more

New generations free of HIV, syphilis, hepatitis B and Chagas disease in the Americas 2018

M. Alonso González; M. B. Mello; L. Sereno; et al. Pan American Health Organization; World Health Organization (Americas); Unicef (2019) C_WHO
- EMTCT Plus
This FY 2017 Malaria Operational Plan presents a detailed implementation plan for Senegal, based on the strategies of PMI and the National Malaria Control Program (NMCP) strategy. It was developed in consultation with the NMCP and with the participation of national and international partners involve ... more
The World Health Organization (WHO) recommends the use of insecticide-treated nets (ITNs) and intermittent preventive treatment in pregnancy (IPTp) as a cost-effective intervention for the prevention of malaria during pregnancy in endemic areas. This study was conducted to investigate: (1) the exten ... more
Évaluation du programme burkinabé dans les districts de Kaya et de Zorgho Objectif. L’objectif central de cette thèse est d’évaluer, dans des conditions réelles d’implantation, les effets du programme burkinabé de prise en charge communautaire du paludisme sur le recours aux soins de ... more
This National Action Plan addresses actions needed to be taken in order to combat antimicrobial resistance (AMR) in the country. It is obligatory to raise awareness of antimicrobial resistance and promote behavioral change through public communication programmes that targets human, animal and plant ... more
Confronted with the important issue of patient safety, in 2002 the Fifty-fifth World Health Assembly adopted a resolution urging countries to pay the closest possible attention to the problem and to strengthen safety and monitoring systems. In May 2004, the Fifty-seventh World Health Assembly approv ... more
The Ghanaian Cabinet approved the antimicrobial resistance (AMR)Policy and Implementation plan(hereafter referred to as the national action plan or NAP)in December 2017, whilst the country case study was in progress. This has set in motion the implementation phase for Ghana, which is a long awaited ... more
Methicillin-resistant Staphylococcus aureus(MRSA) strainsor multidrug-resistant S.aureus, initially described in 1960s,emerged in the last decade as a cause of nosocomial infections responsible for rapidly progressive, potential fatal diseases including life-threatening pneumonia, necrotizing fascii ... more

Situation Analysis and Recommendation: Antibiotic Use and Resistance in Tanzania

Aboud S., R. Mdegela Global Antibiotic Resistance Partnership—Tanzania Working Group (2015) C2
Antibiotics and other antimicrobial agents are invaluable life savers, particularly in resource-limited countries where infectious diseases are abundant. Both uncomplicated and severe infections are potentially curable as long as the aetiological agents are susceptible to the ... more
The leishmaniases are a group of diseases caused by Leishmania spp., which occur in cutaneous, mucocutaneous and visceral forms. They are neglected tropical diseases (NTDs), which disproportionately affect marginalized populations who have limited access to health care. HIV co-infected patients with ... more
A Situational Assessment and Five-YearAction Plan for the Africa CDC Strengthening Regional Public Health Institutions and Capacity for Surveillance and Response Program
Handbook 2
La enfermedad de Chagas es el resultado de la infección por elTrypanosoma cruzi. En Colombia, zona endémica para la enfermedad, existe al menos un millón de personas infectadas y tres millones en riesgo. Por lo anterior, el Ministerio de la Protección Social avaló la creación de una Guía de a ... more
In the Region of the Americas, the leishmaniases are a group of diseases caused by various species of Leishmania, which cause a set of clinical syndromes in infected humans that can involve the skin, mucosa, and visceral organs. The spectrum of clinical disease is varied and depends on the interacti ... more
El manual detalla los procedimientos más apropiados para el diagnóstico de los enteroparásitos descritos en nuestro medio y se espera que sea una ayuda inmediata para el personal técnico y profesional de los laboratorios locales, intermedios y regionales de la Red Nacional de Laboratorios en Sal ... more
Training Modules for climate change and Health - WHO
Lancet Infect Dis 2022; 22: 222–4
Drug registration in Kenya started in 1982; the process mainly involves an evaluation committee at the Kenya Pharmacy and Poisons Board (PPB) that aims to approve products based on quality, safety and efficacy.
The emergence and transmission of zoonotic diseases are driven by complex interactions between health, environmental, and socio-political systems. Human movement is considered a significant and increasing factor in these processes, yet forced migration remains an understudied area of zoonotic res ... more
In 2015, 5.9 million children under age five died (1). The major causes of child deaths globally are pneumonia, prematurity, intrapartum-related complications, neonatal sepsis, congenital anomalies, diarrhoea, injuries and malaria (2). Most of these diseases and conditions are at least partially cau ... more
Brucellosis is widespread in both humans and livestock in many developing countries. The authors have performed a series of epidemiological studies on brucellosis in agro-pastoral areas in Tanzania since 2015, with the aim of the disease control. Previously, the potential of a community-based brucel ... more
Proc Natl Acad Sci U S A v.110(21); 2013 May 21 PMC3666729 ; A systematic review was conducted by a multidisciplinary team to analyze qualitatively best available scientific evidence on the effect of agricultural intensification and environmental changes on the risk of zoonoses for which there are ... more
The arrival and rapid spread of the mosquito-borne viral disease Chikungunya across the Americas is one of the most significant public health developments of recent years, preceding and mirroring the subsequent spread of Zika. Globalization in trade and travel can lead to the importation of these vi ... more
Mortality due to enteric infections is projected to increase because of global warming; however, the different temperature sensitivities of major enteric pathogens have not yet been considered in projections on a global scale. We aimed to project global temperature-attributable enteric infection mor ... more
Published: November 24, 2020 https://doi.org/10.1371/journal.pbio.3000938 Climate change is expected to have complex effects on infectious diseases, causing some to increase, others to decrease, and many to shift their distributions. There have been several important advances in understanding the ... more
WHO Technical Series 971
A systematic analysis for the Global Burden of Disease Study 2019. The Lancet Vol.399 Issue 10341 p.2129-2154 Human resources for health (HRH) include a range of occupations that aim to promote or improve human health. The UN Sustainable Development Goals (SDGs) and the WHO Health Workforce 2030 s ... more
Glob Heart . 2020 Oct 13;15(1):69. doi: 10.5334/gh.891.