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Dyslipidemia, chronic inflammation, and subclinical atherosclerosis in children and adolescents infected with HIV: The PositHIVe Health Study

L. R. Augustemak de Lima; E. L. Petroski; Y. M. F. Moreno; et al. PLOS ONE (2018) CC

Research Article PLOS ONE | https://doi.org/10.1371/journal.pone.0190785 January 10, 2018

Screening for cardiovascular disease risk and subsequent management in low and middle income countries: challenges and opportunities

Bovet, P.; Chiolero, A.; Paccaud, F. et al. Public Health Reviews (2015) CC

Background: Cardiovascular disease (CVD), mainly heart attack and stroke, is the leading cause of premature mortality in low and middle income countries (LMICs). Identifying and managing individuals at high risk of CVD is an important strategy to prevent and control CVD, in addition to multisector ... al population-based interventions to reduce CVD risk factors in the entire population. Methods: We describe key public health considerations in identifying and managing individuals at high risk of CVD in LMICs. Results: A main objective of any strategy to identify individuals at high CVD risk is to maximize the number of CVD events averted while minimizing the numbers of individuals needing treatment. Scores estimating the total risk of CVD (e.g. ten-year risk of fatal and non-fatal CVD) are available for LMICs, and are based on the main CVD risk factors (history of CVD, age, sex, tobacco use, blood pressure, blood cholesterol and diabetes status). Opportunistic screening of CVD risk factors enables identification of persons with high CVD risk, but this strategy can be widely applied in low resource settings only if cost effective interventions are used (e.g. the WHO Package of Essential NCD interventions for primary health care in low resource settings package) and if treatment (generally for years) can be sustained, including continued availability ofaffordable medications and funding mechanisms that allow people to purchase medications without impoverishing them (e.g. universal access to health care). Thisalso emphasises the need to re-orient health systems in LMICs towards chronic diseases management. Conclusion: The large burden of CVD in LMICs and the fact that persons with high CVD can be identified and managed along cost-effective interventions mean that health systems need to be structured in a way that encourages patient registration, opportunistic screening of CVD risk factors, efficient procedures for the management of chronic conditions (e.g. task sharing) and provision of affordable treatment for those with high CVD risk. The focus needs to be in primary care because that is where most of the population can access health care and because CVD programmes can be run effectively at this level. more

The contribution of female community health volunteers (FCHVs) to maternity care in Nepal: a qualitative study

Panday, S., P. Bissell , E.van Teijlingen, et al. (2017) CC

BMC Health Services Research (2017) 17:623 DOI 10.1186/s12913-017-2567-7

Knowing your status: then and now - Realizing the potential of HIV self-testing

Karin Hatzold; E. Corbett; H. Ingold; et al. Unitaid (Innovation in Global Health); World Health Organization (WHO); HIV Self-Testing Africa Initiative (2018) C2

30th World AIDS Day Report STAR Initiative, Unitaid and World Health Organization December 2018

Management of bipolar disorder in the intercontinental region: an international, multicenter, non-interventional, cross-sectional study in real-life conditions

Samalin, L.; E. Vieta, T. Ahmed Okasha, et al. (2016) CC

Sci Rep. 2016; 6: 25920. Published online 2016 May 16. doi: 10.1038/srep25920

Fertilizing Crops to Improve Human Health: A Scientific Review

IPNI, IFA International Plant Nutrition Institute, International Fertilizer Industry Association (2012) C1

- The Role of Plant Nutrition in Supporting Food Security - Micronutrient Malnutrition: Causes, Prevalence, Consequences and Interventions - Fertilizer Application and Nutraceutical Content in Health-Functional Foods - Plant Nutrition and Health Risks Associated with Plant Diseases - Human Heal ... more

The impact of climate change on mental health and emotional wellbeing: current evidence and implications for policy and practice

Lawrence, E.; R. Thompson, G. Fontana, et al. (2021) CC

Empowering Frontline Primary Healthcare Workers in a Global Health Partnership Training of Trainers Intervention to Strengthen the Prevention and Control of Cardiovascular Disease in Mozambique

Harris. P.; Juga, E.; Bay, N. et al. Global Heart (2022) CC

Unpreparedness of health professionals to address non-communicable diseases (NCD) at peripheral health facilities is a critical health system challenge in Mozambique. To address this weakness and decentralize NCD care, training of the primary care workforce is needed. We describe our experience in t ... more

Cardiovascular diseases in Africa in the twenty-first century: Gaps and priorities going forward

Minja, N.W.; Nakagaayi, D.; Aliku, T. et al. Frontiers in Cardiovascular Medicine (2022) CC

In 2015, the United Nations set important targets to reduce premature cardiovascular disease (CVD) deaths by 33% by 2030. Africa disproportionately bears the brunt of CVD burden and has one of the highest risks of dying from non-communicable diseases (NCDs) worldwide. There is currently an epide ... miological transition on the continent, where NCDs is projected to outpace communicable diseases within the current decade. Unchecked increases in CVD risk factors have contributed to the growing burden of three major CVDs—hypertension, cardiomyopathies, and atherosclerotic diseasesleading to devastating rates of stroke and heart failure. The highest age standardized disability-adjusted life years (DALYs) due to hypertensive heart disease (HHD) were recorded in Africa. The contributory causes of heart failure are changing—whilst HHD and cardiomyopathies still dominate, ischemic heart disease is rapidly becoming a significant contributor, whilst rheumatic heart disease (RHD) has shown a gradual decline. In a continent where health systems are traditionally geared toward addressing communicable diseases, several gaps exist to adequately meet the growing demand imposed by CVDs. Among these, high-quality research to inform interventions, underfunded health systems with high out-of-pocket costs, limited accessibility and affordability of essential medicines, CVD preventive services, and skill shortages. Overall, the African continent progress toward a third reduction in premature mortality come 2030 is lagging behind. More can be done in the arena of effective policy implementation for risk factor reduction and CVD prevention, increasing health financing and focusing on strengthening primary health care services for prevention and treatment of CVDs, whilst ensuring availability and affordability of quality medicines. Further, investing in systematic country data collection and research outputs will improve the accuracy of the burden of disease data and inform policy adoption on interventions. This review summarizes the current CVD burden, important gaps in cardiovascular medicine in Africa, and further highlights priority areas where efforts could be intensified in the next decade with potential to improve the current rate of progress toward achieving a 33% reduction in CVD mortality. more

Quality of care for children with severe disease in the Democratic Republic of the Congo

Clarke-Deelder, E., G. Shapira, H. Samaha, et al. (2019) CC

BMC Public Health (2019) 19:1608 https://doi.org/10.1186/s12889-019-7853-3

Technologies of trust in epidemic response: openness, reflexivity and accountability during the 2014–2016 Ebola outbreak in West Africa

Molly J Ryan, Tamara Giles-Vernick, Janice E Graham British Medical Journal (2019) CC

BMJ Glob Health 2019;4:e001272. doi:10.1136/bmjgh-2018-001272 Trust is an essential component of successful cooperative endeavours. The global health response to the 2014–2016 West Africa Ebola outbreak confronted historically tenuous regional relationships of trust. Challenging sociopolitical co ... more

Improving medicines access and use for child health: a guide to developing interventions

Ross-Degnan, D., Vialle-Valentin, C., and Briggs, J. USAID, SIAPS (Systems for Improved Access to Pharmaceuticals and Services) (2015) C1

Submitted to the US Agency for International Development by the Systems for Improved Access to Pharmaceuticals and Services (SIAPS) Program. This manual provides a framework to identify problems and design interventions to improve access to and use of medicines for children. It is a resource for ... more

Guía de intervención mhGAP para los trastornos mentales, neurológicos y por consumo de sustancias en el nivel de atención de salud no especializada Versión 2.0
recommended

World Health Organization WHO PAHO (2017) C_WHO

Las directrices actualizadas del mhGAP, la retroalimentación de información y la evaluación de la versión 1.0 de la GI-mhGAP por los usuarios han permitido la revisión y elaboración de esta versión actualizada de la guía. En el año 2015, se llevó a cabo y se publicó una actualización ... more

Buruli ulcer : diagnosis of Mycobacterium ulcerans disease : a manual for health care providers

F. Portaels; Johnson, P.; Meyers, W. World Health Organization WHO (2001) CC

This manual is to assist health care providers and laboratory scientists to diagnose mycobacterium ulcerans disease (Buruli ulcer). The manual aims to achieve a better understanding of the clinical presentation and its diagnosis. The methods described are tailored to various levels of care and avail ... more

Social determinants approaches to public health: from concept to practice

Erik Blas, Johannes Sommerfeld and Anand Sivasankara Kurup World Health Organization WHO (2011) C_WHO

La enfermedad de Chagas en El Salvador, evolución histórica y desafíos para el control

Organización Panamericana de la Salud OPS (2010) C2

[Presentación] El presente libro, elaborado por integrantes de múltiples generaciones de técnicos e investigadores salvadoreños dedicados a la enfermedad de Chagas, refleja claramente su actual situación epidemiológica, la evolución hist� ... more

Making Implementation Science Work for Children and Adolescents Living With HIV

D. Mark; E. Geng; S. Vorkorper; et al. JAIDS Journal of Acquired Immune Deficiency Syndromes; Ovid (2018) C2

Supplement Article www.jaids.com J Acquir Immune Defic Syndr Volume 78, Supplement 1, August 15, 2018

Tracking infectious diseases in a warming world

Murray, C.A.; L.E. Escobar, R. Lowe et al. British Medical Journal (2020) CC

BMJ 2020; 371 doi: https://doi.org/10.1136/bmj.m3086 Using infectious diseases sensitive to climate as indicators of climate change helps stimulate and inform public health responses

Guia de atención integral de Niñas y Adolescentes embarazadas menores de 15 años - Misiones

UNICEF (2019) C_UNICEF

El presente documento tiene la finalidad de ordenar la atención de las niñas y adolescentes embarazadas menores de 15 años de la provincia de Misiones y de integrar el abordaje de los diversos actores que tienen responsabilidad en esta población específica: salud, educación, desarrollo social ... more