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Annex 3. Dosages of ARV drugs

World Health Organization (2019) C_WHO
Accessed: 19.10.2019

Harm Reduction save lives - HIV and people who inject Drugs

UNAIDS (Joint United Nations Programme on HIVAIDS) (2017) C2
Research Article PLOS ONE | https://doi.org/10.1371/journal.pone.0189770 January 2, 2018

Guideline: Adherence to antiretroviral therapy in adolescents and young adults (expanded version)

L. Fairlie; L. Jankelowitz; H. Ronald; et al. Southern African HIV Clinicians Society; Right to Care (Training Health Seriously) (2017) C2
Recommendations, resources and references A publication of the Southern African HIV Clinicians Society
HIV Treatment
The objectives of these guidelines are to provide recommendations outlining a public health approach to managing people presenting with advanced HIV disease, and to provide guidance on the timing of initiation of antiretroviral therapy (ART) for all ... more
July 2014
BMJ,Dodd PJ, et al. Thorax 2017;72:559–575. doi:10.1136/thoraxjnl-2016-209421
1st edition
Prepared by NGOs: “Legalife-Ukraine”, “Insight”, “Positive Women”, and “Svitanok” For the submission to the 66th CEDAW Session Geneva, Switzerland 13 February 2017 - 03 March 2017

HIV stigma and associated factors among antiretroviral treatment clients in Jimma town, Southwest Ethiopia

N. N. Fido; M. Aman; Z. Brihnu HIVAIDS - Research and Palliative Care; Dovepress; PMC (US National Library of Medicine National Institutes of Health) (2016) CC
HIV/AIDS - Research and Palliative Care 2016:8 183–193

HIV and young people who inject drugs

A. Armstrong; J. Baer; R. Baggaley; et al. UNAIDS; World Health Organization; UNFPA; et al. (2015) C_WHO
Technical Brief

Implementing Comprehensive HIV and HCV Programmes with People Who Inject Drugs

UNAIDS, UNODC (United Nations Office on Drugs and Crime); World Health Organization; et al. (2017) C2
Practical Guidance for collaborative interventions
Thirty-three years after its discovery, the Human Immunodeficiency Virus (HIV), responsible for the AIDS pandemic, remains a major public health problem despite advanced researches providing better diagnostic and therapeutic tools. The virus targets especially CD4+ T cells, leading to deficiency of ... more
100 test methods for 100 active pharmaceutical ingredients For existing Minilab projects that want to replace old manuals or initiatives that want to start new projects, the new "Minilab Edition 2020" can be obtained at the preferential price of 50 € from our logistic partner Technologie Transfer ... more
Guidelines for treatment of drug-susceptible tuberculosis and patient care Uptsate 2017
HIV Treatment - Interim Guidance
HIV treatment Policy brief July 2017 WHO/HIV/2017.18
Kan M et al. Journal of the International AIDS Society 2018, 21(S5):e25139 http://onlinelibrary.wiley.com/doi/10.1002/jia2.25139/full | https://doi.org/10.1002/jia2.25139
BMC Public Health (2016) 16:766 DOI 10.1186/s12889-016-3455-5
Au Burkina Faso, les personnes vivant avec le VIH (PvVIH) ont régulièrement recours à des substances naturelles pour traiter certaines infections opportunistes. C’est ainsi que le suc des feuilles fraîches de Mitracarpus scaber Zucc. ex Schult. & Schult. f. (Rubiaceae) et de Senna alata (L.) R ... more
The following information provides guidance to health care providers attending to the medical needs of HIV-infected adults (including pregnant women) or children displaced from disaster areas who have not yet secured HIV care in the areas where they have relocated. (*) - HHS Panel on ... more
Clinical Infectious Diseases 1586 - 1594 • CID 2016:62 (15 June) • HIV/AIDS
A Systematic Review and Meta-analysis Clinical Infectious Diseases® 2016;62(12):1586–94
The guidelines are aimed at clinical professionals directly involved with and responsible for the care of adults with HIV infection, and at community advocates responsible for promoting the best interests and care of HIV-positive adults. They should be read in conjunction with other published BHIVA ... more
These guidelines provide new and updated recommendations on the use of point-of-care testing in children under 18 months of age and point-of-care tests to monitor treatment in people living with HIV; the treatment monitoring algorithm; and timing of antire ... more
The END TB Strategy Интеграция совместного оказания услуг в связи с ТБ и ВИЧ во всеобъемлющий пакет помощи для потребителей инъекционных наркотиков

Do no Harm - Health, Human Rights and people who use drugs

UNAIDS (Joint United Nations Programme on HIVAIDS) (2019) C2
Accessed: 07.11.2019
Avec l’essor des traitements antirétroviraux (TAR) à base de dolutégravir (DTG) pour soigner les personnes vivant avec le VIH dans le monde, il est important d’estimer la vitesse à laquelle la résistance acquise au DTG apparaît dans les populations sous TAR. Bien que la résistance au DT ... more
PLOS ONE | https://doi.org/10.1371/journal.pone.0192068 March 9, 2018
HIV, viral hepatitis and STI epidemics, particularly among people who inject drugs and other key populations, continue to be fuelled by laws and policies criminalizing sex work; drug use or possession; diverse forms of gender expression and sexualit ... more
This technical report summarizes the discussions on the status of programmatic transition to tenofovir, lamivudine and dolutegravir (TLD) in low– and middle- income countries, addressing the best practices and major challenges faced by HIV programmes. The latest data on safety and efficacy of do ... more
Accessed on 04.04.2023 The Drugs for Neglected Diseases initiative (DNDi) is an international non-profit organization that discovers, develops, and delivers safe, effective, and affordable treatments for the most neglected patients
Made under Section 5 (c) of the Tanzania Food, Drugs and Cosmetics Act, 2003 | Second Edition
Advance copy.

North Macedonia

L. Savikj European Monitoring Centre for Drugs and Drug Addiction (2013) C2
A summary of the national drug situation
The PHC STGs and EML should be used by healthcare workers providing care at clinics, community health centres, and gateway clinics at hospitals. Pharmaceutical and Therapeutics Committees (PTCs) are responsible for ensuring the availability of medicines listed in the PHC EML at those facilities, as ... more
World Drug Report 2018 -2-

EMCDDA Monographs

T. Rhodes; D. Hedrich European Monitoring Centre for Drugs and Drug Addiction (2010) C2
Harm reduction: evidence, impacts and challenges -10-
Accessed: 22.03.2019

Country overview: Tajikistan

European Monitoring Centre for Drugs and Drug Addiction (2015) C2

Country overview: Kyrgyzstan

European Monitoring Centre for Drugs and Drug Addiction (2015) C2

HIV testing and counselling in prisons and other closed settings

UNODC (United Nations of Drugs and Crime); UNAIDS; World Health Organization; United Nations office on drugs and crime (Vienna) (2009) C_WHO
Technical Paper

HIV prevention, treatment and care in prisons and other closed settings: a comprehensive package of interventions

World Health Organization; UNODC (United Nations Office on Drugs and Crime); UNAIDS; et al. (2013) C_WHO
Policy Brief

HIV and young people who sell sex

UNAIDS, UNODC (United Nations Office on Drugs and Crime); World Health Organization; MSMGF; et al. (2015) C_WHO
Technical Brief

Advocacy Guide: HIV/AIDS Prevention among injecting drug users

A. Ball; M. Beg; G. Weiler; et al. World Health Organization; UNAIDS; United Nations on Drugs and Crime (2004) C_WHO
These policy guidelines provide a strategic approach and new recommendations for integrated TB and HIV services for patients suffering from substance-abuse addiction. The key recommendations fall under three main categories: joint planning, key interventions, and overcoming barriers.

Good governance for prison health in 21st century

World Health Organization (Europe); UNODC (United Nations Office on Drugs and Crime) (2013) C_WHO
A policy brief on the organization of prison health
Chapter 1 provides new data on the latest developments in the global treatment effort, highlighting positive trends as well as aspects that require improvement. Chapter 2 summarizes the impact of the scale-up in reducing AIDS-related mortality and new HIV infections. Chapter 3 examines the sequence ... more
The report provides a brief introduction to patents and licences and their effect on the market for antiretroviral (ARV) medicines. It gives an overview of the patent landscape with respect to a select number of ARV medicines in developing countries ... more
Drugs, Diagnostics, Vaccines, Preventive Technologies, Research toward a cure, and immune-based and gene therapies in development
The World Health Organization (WHO) has recommended a universal antiretroviral therapy (ART) for all HIVinfected children before the age of two since 2010, but this implies an early identification of these infants. We described the Prevention of Mot ... more
Co-trimoxazole is a fixed-dose combination of two antimicrobial drugs (sulfamethoxazole and trimethoprim) that covers a variety of bacterial, fungal and protozoan infections. Co-trimoxazole preventive therapy is a feasible, well tolerated and inexpe ... more
Drugs and medical supplies are dispensed at the cutting edge level of the interface between the public health system and the people. Availability or lack of it brings either credit or discredit to the public health system. The primary reason for hol ... more
. MSF Essential Drugs Guidelines دليل عملي موجه للأطباء والصيادلة والممرضين والمساعدين الطبيين
Version 10.1_5 October 2020 These Guidelines are available in different formats: As a paper booklet, a PDF, a mobile app, and now also as a website. The 2019 version of the Guidelines introduces a new drug-drug interaction panel and now consists of six main sections, including a general overview ... more

Policy Analysis and Advocacy Decision Model for HIV-Related Services

B. Pick; D. Wolfe; D. Burrows; F. Hariga; et al. USAID (From the American People); REPFAR; EURASIAN Harm Reduction Network; Health Policy Project (2012) C2
People Who Inject Drugs In addition, the following individuals of our external expert advisory committee made instrumental contributions to the initial design and content of the document: Billy Pick, USAID; Daniel Wolfe, Open Society Foundations; ... more
People living with HIV depend on life-saving antiretroviral therapy (ART) and access to ART must be maintained during periods of travel restrictions and lockdowns resulting from the COVID-19 pandemic. The Information note on HIV and COVID-19 address ... more

HIV Pipeline 2018

i-base (2018) C2
htb supplement: 2018 Vol 19:(1) New drugs in development July 2018 www.i-Base.info
Demographic and socioeconomic data Progress towards HIV testing and treatment cascade targets by 2025 (2023) Health sector cascade (2023) Estimated number of people newly infected with HIV
These guidelines aim to guide all health care providers in Myanmar, accommodating the situation of different settings in the context of progressive decentralization of HIV services. Notable changes from the previous edition include:
• diagnosis of HIV
• update on the initiation of ART
... more
These guidelines provide new and updated recommendations on the use of point-of-care testing in children under 18 months of age and point-of-care tests to monitor treatment in people living with HIV; the treatment monitoring algorithm; and timing of antire ... more
July 2021. This publication brings together important clinical and programmatic updates produced by WHO since 2016 and provides comprehensive, evidence-informed recommendations and good practice statements within a public health, rights-based and person-centred approach. These guidelines bring in ... more
Resumen para Equipos de Salud Edición 2021-2022 Las presentes recomendaciones se encuentran dirigidas a los miembros del equipo de salud que asisten niñas, niños y adolescentes (NNyA) que viven con VIH. También se dirigen a los responsables jurisdiccionales que participan en el proceso de gesti ... more
Early-warning indicators to prevent stock-outs and overstocking of antiretroviral, antituberculosis and antimalaria medicines.

Double Trouble: Injection Drug Use and Sexual Behaviour

Bhattacharya A, et al. India HIVAIDS Alliance; Hridaya Harm Reduction in India (2015) C1
Findings from a cross-sectional qualitative study of HIV vulnerabilities among People Who Inject Drugs and their sex partners in Bihar and Manipur, India. The study is one of the first qualitative comparative studies to seek an in-depth understandin ... more
10 years after the UN general assembly special session on drugs
This guide presents new knowledge and guidelines on the provision of care to persons living with HIV/AIDS, in accordance with the last guidelines of the World Health Organization (WHO) published in 2006 and adapted to the Rwandan national context. It thus responds to the need by the Ministry of Heal ... more
Dolutegravir HIV drug resistance (HIVDR) data from Africa remain sparse. We reviewed HIVDR results of Malawians on dolutegravir-based antiretroviral therapy (November 2020– September 2021). Of 6462 eligible clients, 33 samples were submitted to S ... more
Journal of the International AIDS Society 2017, 20(Suppl 4):21644
National AIDS Programme in Myanmar has made significant progress in scaling up antiretroviral treatment (ART) services and recognizes the importance of differentiated care for pe ... more
This policy brief describes key HIV viral load thresholds and the available viral load testing approaches for monitoring how well antiretroviral therapy is working for people living with HIV. It provides clarification for and elaborates upon the cur ... more
TB heroes Hello, my name is Nurse X My job is to promote integrated HIV and TB prevention, care, treatment and support. This ensures that we, and my team of health care service providers treat everyone who is living with HIV and TB to have all the antire ... more
The uneven distribution of HIV risks and burdens across populations is a well-substantiated fact, though seldom publicly acknowledged. Gay men and other men who have sex with men, people who inject drugs, sex workers, and transgender women are 24, ... more
Reporting period: January 2014 – December 2014
The human immunodeficiency virus (HIV) epidemic in Myanmar is concentrated among men who have sex with men (MSM), people who inject drugs (PWID) and female sex workers (FSW). HIV prevalence in th ... more
Patients with retreatment tuberculosis (TB) represent those who have been treated previously for onemonth ormorewith anti-TB drugs and who have been diagnosed once again with the disease.These patientsmainly include relapses, treatment after fai ... more
The duration of breastfeeding and support from health services to improve feeding practices among mothers living with HIV
This operational guidance, developed by WHO, UNICEF and ENN, outlines the duration of breastfeeding and support from health services to improve infant feeding practices amon ... more
In 2014, GHS/NACP, with support from UNICEF and other partners, conducted a situation analysis on paediatric HIV care and treatment in Ghana. The purpose of this analysis was to identify the gaps within the current delivery of paediatric HIV care and support system and develop a road map for effecti ... more
Journal of the International AIDS Society 2016, 19:20926
There is a growing interest in the potential contribution the private sector can make towards increasing access to antiretroviral therapy (ART) in low‐ and middle‐income settings. Thi ... more
In Vietnam, most of the examination and treatment facilities are facing with of spread of bacteria resistant to many antibiotics. The level and speed of drug resistance are increasing, at alarming level. The burden of drug resistance is increasing due to the increasing cost of treatment, prolonged t ... more
1PEP GUIDELINES | 2019 EDITION. The prevalence of both HIV and Hepatitis B is high in South Africa therefore there is a significant risk of acquiring these infections following exposure to infected material. Studies suggest that post- exposure prophylaxis (PEP) with highly active ... more
A case study from Albania June 2016 EHRN is grateful to all who contributed to this document, especially (in alphabetical order): Alena Alba, Program Officer, Eastern Europe and Central Asia Team, Asia, Europe, Latin America and the Caribbean Department, The Global Fund to Fight AIDS, Tuberc ... more
The main aim of these guidelines is to enable the central units of national TB and HIV/AIDS programmes to support districts to plan, coordinate and implement collaborative TB/HIV activities. These guidelines reinforce current medical understanding, that highly active ... more
The handbook on supply chain management for HIV/AIDS commodities was written to assist program managers to plan and implement day–to-day management of all drugs and medical supplies for an HIV/AIDS program. Many of the suggest ... more
Alternative Thematic Report on implementation of the Convention on Elimination of all Forms of discrimination against Women on the issues related to women living with HIV from the affected groups (women – former prisoners, women using injected drugs ... more
This implementation brief addresses integration of HIV testing services into family planning (FP) services. It is intended as a practical resource for national health programmes seeking to introduce or scale up HIV testing and linkage to HIV prevention, sexually transmitted infection, and ... more
Global and Regional Data 1 December 2021; The 90–90–90 targets were missed, but not by much. At the end of 2020, 84% of people living with HIV knew their HIV status, 87% of people living with HIV who knew their HIV status were accessing antiretroviral ... more
UNAIDS is calling on governments to ensure that the right to health is realized by all by prioritizing public investments in health. At least half of the world’s population cannot access essential health services. Every two minutes a woman dies while giving birth. Among the people being left behin ... more
Time has seen management for Cystic Fibrosis (CF) advance drastically, most recently in the development of the disease-modifying triple combination therapy ivacaftor/tezacaftor/elexacaftor. There is currently limited evidence regarding both the global epidemiology of CF and access to this transforma ... more
Multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) increasingly occur in resource-constrained settings. In the context of a national response to MDR- and XDR-TB, health workers in TB clinics (in district hospitals and some accredited health centres) wil ... more
Barriers to HIV Services and Treatment for Persons with Disabilities in Zambia The 80-page report documents the obstacles faced by people with disabilities in both the community and healthcare settings. These include pervasive stigma and discrimination, lack of access to inclusive HIV prevention ed ... more
The mandate of the National Tuberculosis Control Programme is to provide leadership and stewardship to accelerate intense and coordinated efforts to reduce the adult TB burden of 290 per 100,000 population recently established in the 2013 National TB Prevalence Survey. Other key challenges are low T ... more
The present Consolidated guidelines include a comprehensive set of WHO recommendations for the treatment and care of DR-TB, derived from these WHO guidelines documents. The consolidated guidelines include policy recommendations on treatment regimens for isoniazid-resistant TB (Hr-TB) and MDR/RR-TB, ... more
Antimicrobial resistance (AMR) is an important public health concern shared by developed and developing countries. In developing countries the burden of infectious diseases is greater and exacerbated by limited access to, and availability and affordability of, antimicrobials required to treat infect ... more
Spread of resistance to antimicrobial agents (AMR) does not know national borders and has reached dimensions, which require immediate actions at the national, regional and global levels. Antibiotic resistance is a natural biological response to improper use of antimicrobial agents (AMA); increasing ... more