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Antimicrobial resistance (AMR) has emerged as a leading cause of death in the African region, surpassing fatalities from malaria, HIV, and TB. In response to this critical threat, the region has adopted the AMR Global Action Plan and the ... Union Framework for Antimicrobial Resistance Control 2020 – 2025, which is tailored to meet the specific needs of African nations through a coordinated approach. While most countries in the region have developed and prioritized National Action Plans (NAPs) to tackle AMR, the overall response remains inadequate given the magnitude of the threat, which endangers human, animal, environmental, aquatic, and plant health.
Africa bears a significant burden of infectious diseases, accounting for approximately 95% of malaria deaths, 70% of people living with HIV, and 25% of TB deaths globally. In 2019, AMR was linked to approximately 55,000 deaths from HIV, 30,000 from malaria, and 255,000 overall. Major drivers of AMR in the region include the overuse and misuse of antimicrobials in human and food systems, migration, suboptimal vaccination rates, and environmental contamination from hospital and pharmaceutical effluents. Additionally, there is a lack of access to quality-assured antimicrobials and diagnostics, compounded by inadequate knowledge about AMR. Unlike high-income countries, where indiscriminate antimicrobial use is the primary factor driving AMR, African countries face additional challenges, including a lack of access to clean and safe water, poor Water, Sanitation, and Hygiene (WASH) programs, inadequate infection prevention measures, and suboptimal vaccinations for preventable diseases. One in three hospitals in the region lacks clean, safe running water, and one in eight people defecate openly due to inadequate sanitation. Investments in WASH, infection prevention, and biosecurity could save approximately 700,000 lives annually.
Addressing AMR in Africa requires a comprehensive, multi-sectoral approach involving the entire society. Sustainable access to antimicrobials, including antibiotics, vaccines, and therapeutics, is crucial, as lack of access leads to more morbidity and mortality than AMR itself. Support for the region should focus on preventing infections, strengthening health and food systems, developing human resources, ensuring sustainable access to diagnostics and therapeutics, and investing in laboratory infrastructure to support surveillance and data generation.
Heart failure with a reduced ejection fraction (HFrEF) is a condition frequently encountered by healthcare professionals and, in order to achieve the best outcomes for patients, needs to be managed optimally. This guideline document is based on the European Society of Cardiology Guidelines for the t...
An estimated 59 000 people die from rabies each year. That’s one person every nine minutes of every day, 40% of whom are children living in Asia and Africa. As dog bites cause almost all human cases, we can prevent rabies deaths by increasing awar...
The Global Vaccine Action Plan (GVAP) 2011-2020, endorsed by Member States during the May 2012 World Health Assembly, has set ambitious targets to improve access to immunization and tackle vaccine-preventable diseases. This responsibility has been translated into firm commitments in February 2016, t...
Since May 2019, Confirmation of 4 new emergence of type 2 vaccine-derived poliovirus (VDPV2) in Bambari (2) and Bimbo (2) health districts without any genetic link between them and other known viruses ; Bambari Health District: CAF-RS4-BAM-19-058, onset of paralysis: May 02, 2019. 07 positive contac...
This bi-weekly brief details the latest developments in scientific knowledge and public health policy from around the world as well as updates to the COVID-19-related guidance from Africa CDC, WHO a...
“Guide to facilitate the implementation of the WHO/UNICEF “Guidance on developing a national deployment and vaccination plan for COVID-19 vaccines” for Africa
Risk of spill-over of EVD to Uganda has been categorised as very high. On 28 September 2018, WHO elevated the risk at the regional level which includes Uganda from ‘high’ to ‘very high’. Uganda has a very long and largely porous border with the DRC. High population movements across the borde...
The Regional strategy for measles control recommends that a second opportunity for measles immunization be provided to all children irrespective of their vaccination status or history of clinical measles. The preferred method of provision of a secon...
Pan African Medical Journal 2017;27:215. doi: 10.11604/pamj.2017.27.215.12994
Nature | Vol 600 | 2 December 2021 |
A quick reference guide for health authorities and health-care workers
Revised 2015
Guide pour augmenter la couverture et l'équité dans toutes les communautés de la Région africaine (2017)
Les programmes élargis de vaccination (PEV) sont responsables des vaccins et luttent contre les maladies évitables par la ..., dans le but de les éliminer, voire les éradiquer. La présence de systèmes de vaccination solides, aptes à apporter des vaccins à ceux qui en ont le plus besoin, jouera un rôle important dans la réalisation des objectifs de santé et d'équité aussi bien que des objectifs économiques de plusieurs buts de développement mondial. Ces buts comprennent les objectifs de développement durable (ODD) à l'horizon 2030, la Décennie de la vaccination (2011-2020), le programme pour réaliser la couverture universelle d'ici à 2030, le Plan d'action mondial pour les vaccins (2011-2020), les Stratégies et pratiques mondiales de vaccination systématique et le Plan stratégique régional pour la vaccination 2014-2020.
Les programmes élargis de vaccination (PEV) sont responsables des vaccins et luttent contre les maladies évitables par la ..., dans le but de les éliminer, voire les éradiquer. La présence de systèmes de vaccination solides, aptes à apporter des vaccins à ceux qui en ont le plus besoin, jouera un rôle important dans la réalisation des objectifs de santé et d'équité aussi bien que des objectifs économiques de plusieurs buts de développement mondial. Ces buts comprennent les objectifs de développement durable (ODD) à l'horizon 2030, la Décennie de la vaccination (2011-2020), le programme pour réaliser la couverture universelle d'ici à 2030, le Plan d'action mondial pour les vaccins (2011-2020), les Stratégies et pratiques mondiales de vaccination systématique et le Plan stratégique régional pour la vaccination 2014-2020.
Rabies is a global public health problem with important socioeconomic impacts. Human rabies is preventable; almost all cases are transmitted through the bite of a rabid dog. Elimination of human rabies is possible. Technical support and tools are available. This report covers:
- Why investment ...
- Why investment ...
This module introduces the “Vaccinator’s Manual”, a guideline for vaccinators. The aim of the manual is to update EPI guidelines to include all the changes since the third edition of the Vaccinators Manual (2008)
21 May 2021. he Practical Approach to Care Kit – PACK – is used by nurses, doctors and community health workers in their everyday work to care for patients at the clinic and in the community – PACK Adult, PACK Adolescent, PACK Child and PACK Community.
PACK Adult is also known as APC (Adult P...
