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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

RDC - Tanganyika : Enquête d'intentions - Sites d'Elya, de Kisalaba et de Kabembe (29 Octobre- 5 Novembre 2024)

International Organization for Migration IOM (2024) C2

Depuis fin 2016, des crises humanitaires consécutives liées aux conflits intercommunautaires et attaques des groupes armés secouent la province du Tanganyika en République Démocratique du Congo. Ce contexte a entraîné des déplacements importants de populations, dont certaines ont trouvé ref... more

Standards and recommendations for burns care in mass casualty incidents

World Health Organization WHO (2024) C_WHO

Caring for burns patients from the incident scene to definitive treatment can be a complex, resource-consuming process with the potential to overwhelm health system capacity.This document provides practical guidance for building capacity and capability for burns care from clinical, human resources a... more

Global update on implementation of preventive chemotherapy against neglected tropical diseases (‎NTDs)‎ in 2023 and status of donated medicines for NTDs in 2024

World Health Organization WHO (2024) C_WHO

760 WEEKLY EPIDEMIOLOGICAL RECORD, NOS. 51/52, 20 DECEMBER 2024, pp.760-769. In French and English

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Savoir pour Sauver
recommended

United Nations Children's Fund (UNICEF) (2010) C_UNICEF

Savoir pour Sauver rassemble des informations qui permettent de sauver la vie d’enfants, d’améliorer leur existence et de les protéger. Ces informations devraient être diffusées à grande échelle auprès des familles, des agents de santé, des enseignants, des associations de jeunes ou de f... more

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Management of Waste from Injection Activities at District Level
recommended

World Health Organization (2006) C_WHO

Guidelines for District Health Managers

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Essentials For Emergencies

World Health Organization (2004) C_WHO

The purpose of this booklet is to assist WHO and other Public Health workers in the field when an emergency occurs. The booklet provides technical hints on how to carry out a rapid health assessment, how to facilitate coordination, how departments in WHO can assist, etc. Standard formats for re... more

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Emergency Response Framework

World Health Organization (2013) C_WHO

The 2nd edition is publised in 2017.

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Nutrition Guidelines
recommended

Médecins sans Frontières (2006) C1

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Gender, Climate Change and Health

World Health Organization (WHO) (2014) C_WHO

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Evaluation of Humanitarian Action (EHA). Course Reference Manual

Margie Buchanan-Smith and John Cosgrave Channel Research; ALNAP (2010)

This manual is for the beginner/intermediate and advanced EHA courses run by Channel Research on behalf of ALNAP. It is supported by a course specific set of case studies and exercises and by a bibliography of evaluation references

Recommendations for management of common childhood conditions
recommended

World Health Organization (2012)

Evidence for technical update of pocket book recommendations. Newborn conditions, dysentery, pneumonia, oxygen use and delivery, common causes of fever, severe acute malnutrition and supportive care

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Crisis Standards of Care: A Toolkit for Indicators and Triggers

Dan Hanfling, John Hick, and Clare Stroud Dan Hanfling, John Hick, and Clare Stroud (2013)

(You need free registration to download the book) Disasters and public health emergencies can stress health care systems to the breaking point and disrupt delivery of vital medical services. During such crises, hospitals and long-term care facilities may be without power; trained staff, ambulances,... more

Communication for Behavioural Impact (COMBI)

UNIECF; WHO; FAO (2012)

A toolkit for behavioural and social communication in outbreak response

Missed: Polio Communications Quarterly Update – October 2012

United Nations Children’s Fund (UNICEF) UNICEF (2012)

With a focus on Pakistan and Nigeria’s most vulnerable communities, this report provides insight about the role that community push-back is playing in the transmission of the polio virus and how the Global Polio Eradication Initiative (GPEI) can mitigate these social risks to reach every missed ch... more

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Humanitarian Supply Management System SUMA

Pan American Health Organization (2000)

Manual Logistical Management of Humanitarian Supply The flood of relief supplies that arrive in the aftermath of large-scale disasters often poses serious logistic and management problems for national authorities. SUMA is a tool for the management of humanitarian relief supplies, from the time pled... more

Consolidated Humanitarian Health Guidelines

ECHO EU (2014)

These Guidelines comprise a General Guidelines document that provides the basic parameters of DG ECHO humanitarian health assistance, complemented by specific Technical Guidance in annex.

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Operational Guidelines For Community Care Centres

National AIDS Control Organisation, Ministry of Health &; Family Welfare , Government of India, (2007)

Communication for Behavioural Impact (COMBI) Toolkit

World Health Organization (2012)

This field workbook supports the implementation of the interagency (FAO, UNICEF, WHO) “Communication for Behavioural Impact (COMBI): A toolkit for behavioural and social communication in outbreak response”. It is a handheld guide and notebook for applying the WHO COMBI methodology in 7-steps, du... more

Élimination sans risques des déchets

Organisation Mondiale de la Santé OMS (1998)

Savoir pour Sauver recommended

Management of Waste from Injection Activities at District Level recommended

Nutrition Guidelines recommended

Recommendations for management of common childhood conditions recommended

Savoir pour Sauver
recommended

Management of Waste from Injection Activities at District Level
recommended

Nutrition Guidelines
recommended

Recommendations for management of common childhood conditions
recommended